메뉴 건너뛰기




Volumn 14, Issue 12, 2016, Pages 1335-1347

Advanced heart failure: an appraisal of the potential of levosimendan in this end-stage scenario and some related ethical considerations

Author keywords

ethics; Heart failure; inodilator; kidney function; levosimendan; palliative care; quality of life

Indexed keywords

LEVOSIMENDAN; CARDIOTONIC AGENT; HYDRAZONE DERIVATIVE; PYRIDAZINE DERIVATIVE; SIMENDAN;

EID: 84996508850     PISSN: 14779072     EISSN: 17448344     Source Type: Journal    
DOI: 10.1080/14779072.2016.1247694     Document Type: Review
Times cited : (15)

References (112)
  • 1
    • 84985960368 scopus 로고    scopus 로고
    • Medical resource use and expenditure in patients with chronic heart failure: a population-based analysis of 88 195 patients
    • Apr
    • Farré N, Vela E, Clèries M, et al. Medical resource use and expenditure in patients with chronic heart failure:a population-based analysis of 88 195 patients. Eur J Heart Fail. 2016;18:1132–1140. published online 2016 Apr25. DOI:10.1002/ejhf.549
    • (2016) Eur J Heart Fail , vol.18 , pp. 1132-1140
    • Farré, N.1    Vela, E.2    Clèries, M.3
  • 3
    • 77955937856 scopus 로고    scopus 로고
    • Quality of life in chronic disease: a comparison between patients with heart failure and patients with aphasia after stroke
    • Franzén-Dahlin A, Karlsson MR, Mejhert M, et al. Quality of life in chronic disease:a comparison between patients with heart failure and patients with aphasia after stroke. J Clin Nurs. 2010;19:1855–1860.
    • (2010) J Clin Nurs , vol.19 , pp. 1855-1860
    • Franzén-Dahlin, A.1    Karlsson, M.R.2    Mejhert, M.3
  • 4
    • 84958636447 scopus 로고    scopus 로고
    • Sleep-disordered breathing in heart failure
    • Pearse SG, Cowie MR., Sleep-disordered breathing in heart failure. Eur J Heart Fail. 2016;18:353–361.
    • (2016) Eur J Heart Fail , vol.18 , pp. 353-361
    • Pearse, S.G.1    Cowie, M.R.2
  • 5
    • 84954400473 scopus 로고    scopus 로고
    • Depression and anxiety as predictors of mortality among heart failure patients: systematic review and meta-analysis
    • Sokoreli I, de Vries JJ, Pauws SC, et al. Depression and anxiety as predictors of mortality among heart failure patients:systematic review and meta-analysis. Heart Fail Rev. 2016;21:49–63.
    • (2016) Heart Fail Rev , vol.21 , pp. 49-63
    • Sokoreli, I.1    de Vries, J.J.2    Pauws, S.C.3
  • 6
    • 84959870921 scopus 로고    scopus 로고
    • Burdensome physical and depressive symptoms predict heart failure-specific health status over one year
    • Lum HD, Carey EP, Fairclough D, et al. Burdensome physical and depressive symptoms predict heart failure-specific health status over one year. J Pain Symptom Manage. 2016;51:963–970.
    • (2016) J Pain Symptom Manage , vol.51 , pp. 963-970
    • Lum, H.D.1    Carey, E.P.2    Fairclough, D.3
  • 7
    • 84882269003 scopus 로고    scopus 로고
    • The CHARMS study: cardiac patients’ experiences of sexual problems following cardiac rehabilitation
    • Byrne M, Doherty S, Murphy AW, et al. The CHARMS study:cardiac patients’ experiences of sexual problems following cardiac rehabilitation. Eur J Cardiovasc Nurs. 2013;12:558–566.
    • (2013) Eur J Cardiovasc Nurs , vol.12 , pp. 558-566
    • Byrne, M.1    Doherty, S.2    Murphy, A.W.3
  • 8
    • 84900528378 scopus 로고    scopus 로고
    • Sexuality of patients with chronic heart failure and their spouses and the need for information regarding sexuality
    • Driel AG, de Hosson MJ, Gamel C. Sexuality of patients with chronic heart failure and their spouses and the need for information regarding sexuality. Eur J Cardiovasc Nurs. 2014;13:227–234.
    • (2014) Eur J Cardiovasc Nurs , vol.13 , pp. 227-234
    • Driel, A.G.1    de Hosson, M.J.2    Gamel, C.3
  • 9
    • 84885038007 scopus 로고    scopus 로고
    • Preferences of heart failure patients in daily clinical practice: quality of life or longevity?
    • Kraai IH, Vermeulen KM, Luttik ML, et al. Preferences of heart failure patients in daily clinical practice:quality of life or longevity? Eur J Heart Fail. 2013;15:1113–1121.
    • (2013) Eur J Heart Fail , vol.15 , pp. 1113-1121
    • Kraai, I.H.1    Vermeulen, K.M.2    Luttik, M.L.3
  • 10
    • 85026151040 scopus 로고    scopus 로고
    • Intermittent positive inotrope infusion in the management of end-stage, low-output heart failure
    • Levine BS. Intermittent positive inotrope infusion in the management of end-stage, low-output heart failure. J Cardiovasc Nurs. 2000;14:76–93.
    • (2000) J Cardiovasc Nurs , vol.14 , pp. 76-93
    • Levine, B.S.1
  • 11
    • 77956269007 scopus 로고    scopus 로고
    • Inotropic therapy for end-stage heart failure patients
    • Toma M, Starling RC. Inotropic therapy for end-stage heart failure patients. Curr Treat Options Cardiovasc Med. 2010;12:409–419.
    • (2010) Curr Treat Options Cardiovasc Med , vol.12 , pp. 409-419
    • Toma, M.1    Starling, R.C.2
  • 12
    • 84928891158 scopus 로고    scopus 로고
    • A Bayesian network meta-analysis on the effect of inodilatory agents on mortality
    • Greco T, Calabrò MG, Covello RD, et al. A Bayesian network meta-analysis on the effect of inodilatory agents on mortality. Br J Anaesth. 2015;114:746–756.
    • (2015) Br J Anaesth , vol.114 , pp. 746-756
    • Greco, T.1    Calabrò, M.G.2    Covello, R.D.3
  • 13
    • 0031824977 scopus 로고    scopus 로고
    • Clinical definition and epidemiology of advanced heart failure
    • Adams KF, Zannad F. Clinical definition and epidemiology of advanced heart failure. Am Heart J. 1998;135:S204–S215.
    • (1998) Am Heart J , vol.135 , pp. S204-S215
    • Adams, K.F.1    Zannad, F.2
  • 14
    • 34248226980 scopus 로고    scopus 로고
    • Advanced chronic heart failure: a position statement from the study group of advanced heart failure of the heart failure association of the European society of cardiology
    • Metra M, Ponikowski P, Dickstein K, et al. Advanced chronic heart failure:a position statement from the study group of advanced heart failure of the heart failure association of the European society of cardiology. Eur J Heart Fail. 2007;9:684–694.• Guideline statement.
    • (2007) Eur J Heart Fail , vol.9 , pp. 684-694
    • Metra, M.1    Ponikowski, P.2    Dickstein, K.3
  • 15
    • 84901196872 scopus 로고    scopus 로고
    • Repetitive use of levosimendan for treatment of chronic advanced heart failure: clinical evidence, practical considerations, and perspectives: an expert panel consensus
    • Nieminen MS, Altenberger J, Ben-Gal T, et al. Repetitive use of levosimendan for treatment of chronic advanced heart failure:clinical evidence, practical considerations, and perspectives:an expert panel consensus. Int J Cardiol. 2014;174:360–367.• Systematic review.
    • (2014) Int J Cardiol , vol.174 , pp. 360-367
    • Nieminen, M.S.1    Altenberger, J.2    Ben-Gal, T.3
  • 16
    • 84871208411 scopus 로고    scopus 로고
    • Quality of life and survival in patients with heart failure
    • Hoekstra T, Jaarsma T, van Veldhuisen DJ, et al. Quality of life and survival in patients with heart failure. Eur J Heart Fail. 2013;15:94–102.
    • (2013) Eur J Heart Fail , vol.15 , pp. 94-102
    • Hoekstra, T.1    Jaarsma, T.2    van Veldhuisen, D.J.3
  • 18
    • 84866089011 scopus 로고    scopus 로고
    • The registry of the international society for heart and lung transplantation: 29th official adult heart transplant report-2012
    • Stehlik J, Edwards LB, Kucheryavaya AY, et al. The registry of the international society for heart and lung transplantation:29th official adult heart transplant report-2012. J Heart Lung Transplant. 2012;31:1052–1064.
    • (2012) J Heart Lung Transplant , vol.31 , pp. 1052-1064
    • Stehlik, J.1    Edwards, L.B.2    Kucheryavaya, A.Y.3
  • 19
    • 0035892018 scopus 로고    scopus 로고
    • Long-term use of a left ventricular assist device for end-stage heart failure
    • Rose EA, Gelijns AC, Moskowitz AJ, et al. Long-term use of a left ventricular assist device for end-stage heart failure. N Engl J Med. 2001;345:1435–1443.
    • (2001) N Engl J Med , vol.345 , pp. 1435-1443
    • Rose, E.A.1    Gelijns, A.C.2    Moskowitz, A.J.3
  • 20
    • 84944067756 scopus 로고    scopus 로고
    • Risk assessment and comparative effectiveness of left ventricular assist device and medical management in ambulatory heart failure patients: results from the ROADMAP study
    • Estep JD, Starling RC, Horstmanshof DA, et al. Risk assessment and comparative effectiveness of left ventricular assist device and medical management in ambulatory heart failure patients:results from the ROADMAP study. J Am Coll Cardiol. 2015;66:1747–1761.
    • (2015) J Am Coll Cardiol , vol.66 , pp. 1747-1761
    • Estep, J.D.1    Starling, R.C.2    Horstmanshof, D.A.3
  • 21
    • 34547759704 scopus 로고    scopus 로고
    • Chronic mechanical circulatory support for inotrope-dependent heart failure patients who are not transplant candidates: results of the INTrEPID trial
    • Rogers JG, Butler J, Lansman SL, et al. Chronic mechanical circulatory support for inotrope-dependent heart failure patients who are not transplant candidates:results of the INTrEPID trial. J Am Coll Cardiol. 2007;50:741–747.
    • (2007) J Am Coll Cardiol , vol.50 , pp. 741-747
    • Rogers, J.G.1    Butler, J.2    Lansman, S.L.3
  • 22
    • 84961727444 scopus 로고    scopus 로고
    • Levosimendan meta-analyses: is there a pattern in the effect on mortality?
    • Pollesello P, Parissis J, Kivikko M, et al. Levosimendan meta-analyses:is there a pattern in the effect on mortality? Int J Cardiol. 2016;209:77–83.
    • (2016) Int J Cardiol , vol.209 , pp. 77-83
    • Pollesello, P.1    Parissis, J.2    Kivikko, M.3
  • 23
    • 1642441317 scopus 로고    scopus 로고
    • The effects of levosimendan and OR-1896 on isolated hearts, myocyte-sized preparations and phosphodiesterase enzymes of the guinea pig
    • Szilágyi S, Pollesello P, Levijoki J, et al. The effects of levosimendan and OR-1896 on isolated hearts, myocyte-sized preparations and phosphodiesterase enzymes of the guinea pig. Eur J Pharmacol. 2004;486:67–74.
    • (2004) Eur J Pharmacol , vol.486 , pp. 67-74
    • Szilágyi, S.1    Pollesello, P.2    Levijoki, J.3
  • 24
    • 0030608872 scopus 로고    scopus 로고
    • Levosimendan, a novel Ca2+ sensitizer, activates the glibenclamide-sensitive K+ channel in rat arterial myocytes
    • Yokoshiki H, Katsube Y, Sunagawa M, et al. Levosimendan, a novel Ca2+ sensitizer, activates the glibenclamide-sensitive K+ channel in rat arterial myocytes. Eur J Pharmacol. 1997;333:249–259.
    • (1997) Eur J Pharmacol , vol.333 , pp. 249-259
    • Yokoshiki, H.1    Katsube, Y.2    Sunagawa, M.3
  • 25
    • 3843094875 scopus 로고    scopus 로고
    • Potassium-specific effects of levosimendan on heart mitochondria
    • Kopustinskiene DM, Pollesello P, Saris NE. Potassium-specific effects of levosimendan on heart mitochondria. Biochem Pharmacol. 2004;68:807–812.
    • (2004) Biochem Pharmacol , vol.68 , pp. 807-812
    • Kopustinskiene, D.M.1    Pollesello, P.2    Saris, N.E.3
  • 26
    • 0037142946 scopus 로고    scopus 로고
    • Efficacy and safety of intravenous levosimendan compared with dobutamine in severe low-output heart failure (the LIDO study): a randomized double-blind trial
    • Follath F, Cleland JG, Just H, et al. Efficacy and safety of intravenous levosimendan compared with dobutamine in severe low-output heart failure (the LIDO study):a randomized double-blind trial. Lancet. 2002;360:196–202.
    • (2002) Lancet , vol.360 , pp. 196-202
    • Follath, F.1    Cleland, J.G.2    Just, H.3
  • 27
    • 0034739460 scopus 로고    scopus 로고
    • Acute hemodynamic and clinical effects of levosimendan in patients with severe heart failure
    • Slawsky MT, Colucci WS, Gottlieb SS, et al. Acute hemodynamic and clinical effects of levosimendan in patients with severe heart failure. Circulation. 2000;102:2222–2227.
    • (2000) Circulation , vol.102 , pp. 2222-2227
    • Slawsky, M.T.1    Colucci, W.S.2    Gottlieb, S.S.3
  • 28
    • 84877960102 scopus 로고    scopus 로고
    • Effect of levosimendan on the short-term clinical course of patients with acutely decompensated heart failure
    • Packer M, Colucci W, Fisher L, et al. Effect of levosimendan on the short-term clinical course of patients with acutely decompensated heart failure. JACC Heart Fail. 2013;1:103–112.
    • (2013) JACC Heart Fail , vol.1 , pp. 103-112
    • Packer, M.1    Colucci, W.2    Fisher, L.3
  • 29
    • 34247857479 scopus 로고    scopus 로고
    • Levosimendan vs dobutamine for patients with acute decompensated heart failure: the SURVIVE randomized trial
    • Mebazaa A, Nieminen MS, Packer M, et al. Levosimendan vs dobutamine for patients with acute decompensated heart failure:the SURVIVE randomized trial. JAMA. 2007;297:1883–1891.
    • (2007) JAMA , vol.297 , pp. 1883-1891
    • Mebazaa, A.1    Nieminen, M.S.2    Packer, M.3
  • 30
    • 0034669441 scopus 로고    scopus 로고
    • Hemodynamic and neurohumoral effects of continuous infusion of levosimendan in patients with congestive heart failure
    • Nieminen MS, Akkila J, Hasenfuss G, et al. Hemodynamic and neurohumoral effects of continuous infusion of levosimendan in patients with congestive heart failure. J Am Coll Cardiol. 2000;36:1903–1912.
    • (2000) J Am Coll Cardiol , vol.36 , pp. 1903-1912
    • Nieminen, M.S.1    Akkila, J.2    Hasenfuss, G.3
  • 31
    • 33846082231 scopus 로고    scopus 로고
    • Duration of the hemodynamic action of a 24-h infusion of levosimendan in patients with congestive heart failure
    • Lilleberg J, Laine M, Palkama T, et al. Duration of the hemodynamic action of a 24-h infusion of levosimendan in patients with congestive heart failure. Eur J Heart Fail. 2007;9:75–82.
    • (2007) Eur J Heart Fail , vol.9 , pp. 75-82
    • Lilleberg, J.1    Laine, M.2    Palkama, T.3
  • 32
    • 84941621522 scopus 로고    scopus 로고
    • The patient perspective: quality of life in advanced heart failure with frequent hospitalisations
    • Nieminen MS, Dickstein K, Fonseca C, et al. The patient perspective:quality of life in advanced heart failure with frequent hospitalisations. Int J Cardiol. 2015;191:256–264.•• International consensus on quality of life and trade-off.
    • (2015) Int J Cardiol , vol.191 , pp. 256-264
    • Nieminen, M.S.1    Dickstein, K.2    Fonseca, C.3
  • 33
    • 0037422531 scopus 로고    scopus 로고
    • Sustained hemodynamic effects of intravenous levosimendan
    • Kivikko M, Lehtonen L, Colucci WS. Sustained hemodynamic effects of intravenous levosimendan. Circulation. 2003;107:81–86.
    • (2003) Circulation , vol.107 , pp. 81-86
    • Kivikko, M.1    Lehtonen, L.2    Colucci, W.S.3
  • 34
    • 65549133015 scopus 로고    scopus 로고
    • Levosimendan vs. dobutamine: outcomes for acute heart failure patients on beta-blockers in SURVIVE
    • Mebazaa A, Nieminen MS, Filippatos GS, et al. Levosimendan vs. dobutamine:outcomes for acute heart failure patients on beta-blockers in SURVIVE. Eur J Heart Fail. 2009;11:304–311.
    • (2009) Eur J Heart Fail , vol.11 , pp. 304-311
    • Mebazaa, A.1    Nieminen, M.S.2    Filippatos, G.S.3
  • 35
    • 77950251147 scopus 로고    scopus 로고
    • Intravenous levosimendan vs. dobutamine in acute decompensated heart failure patients on beta-blockers
    • Apr
    • Bergh CH, Andersson B, Dahlström U, et al. Intravenous levosimendan vs. dobutamine in acute decompensated heart failure patients on beta-blockers. Eur J Heart Fail. 2010 Apr;12(4):404–410.
    • (2010) Eur J Heart Fail , vol.12 , Issue.4 , pp. 404-410
    • Bergh, C.H.1    Andersson, B.2    Dahlström, U.3
  • 36
    • 0031976338 scopus 로고    scopus 로고
    • Effects of a new calcium sensitizer, levosimendan, on hemodynamic, coronary blood flow and myocardial substrate utilization early after coronary artery bypass grafting
    • Lilleberg J, Nieminen MS, Akkila J, et al. Effects of a new calcium sensitizer, levosimendan, on hemodynamic, coronary blood flow and myocardial substrate utilization early after coronary artery bypass grafting. Eur Heart J. 1998;19:660–668.
    • (1998) Eur Heart J , vol.19 , pp. 660-668
    • Lilleberg, J.1    Nieminen, M.S.2    Akkila, J.3
  • 37
    • 0033696857 scopus 로고    scopus 로고
    • Myocardial efficiency during levosimendan infusion in congestive heart failure
    • Ukkonen H, Saraste M, Akkila J, et al. Myocardial efficiency during levosimendan infusion in congestive heart failure. Clin Pharmacol Ther. 2000;68:522–531.
    • (2000) Clin Pharmacol Ther , vol.68 , pp. 522-531
    • Ukkonen, H.1    Saraste, M.2    Akkila, J.3
  • 38
    • 0042092537 scopus 로고    scopus 로고
    • Clinical use of inotropic therapy for heart failure: looking backward or forward? Part I: inotropic infusions during hospitalization
    • Stevenson LW. Clinical use of inotropic therapy for heart failure:looking backward or forward? Part I:inotropic infusions during hospitalization. Circulation. 2003;108:367–372.
    • (2003) Circulation , vol.108 , pp. 367-372
    • Stevenson, L.W.1
  • 39
    • 0041663591 scopus 로고    scopus 로고
    • Clinical use of inotropic therapy for heart failure: looking backward or forward? Part II: chronic inotropic therapy
    • Stevenson LW. Clinical use of inotropic therapy for heart failure:looking backward or forward? Part II:chronic inotropic therapy. Circulation. 2003;108:492–497.
    • (2003) Circulation , vol.108 , pp. 492-497
    • Stevenson, L.W.1
  • 40
    • 2342505687 scopus 로고    scopus 로고
    • Effects of levosimendan on circulating pro-inflammatory cytokines and soluble apoptosis mediators in patients with decompensated advanced heart failure
    • Parissis JT, Adamopoulos S, Antoniades C, et al. Effects of levosimendan on circulating pro-inflammatory cytokines and soluble apoptosis mediators in patients with decompensated advanced heart failure. Am J Cardiol. 2004;93:1309–1312.
    • (2004) Am J Cardiol , vol.93 , pp. 1309-1312
    • Parissis, J.T.1    Adamopoulos, S.2    Antoniades, C.3
  • 41
    • 84856185198 scopus 로고    scopus 로고
    • Effects of levosimendan on mortality and hospitalization. A meta-analysis of randomized controlled studies
    • Landoni G, Biondi-Zoccai G, Greco M, et al. Effects of levosimendan on mortality and hospitalization. A meta-analysis of randomized controlled studies. Crit Care Med. 2012;40:634–646.
    • (2012) Crit Care Med , vol.40 , pp. 634-646
    • Landoni, G.1    Biondi-Zoccai, G.2    Greco, M.3
  • 42
    • 84981715657 scopus 로고    scopus 로고
    • ESC guidelines for the diagnosis and treatment of acute and chronic heart failure: the task force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC). Developed with the special contribution of the Heart Failure Association (HFA) of the ESC
    • Ponikowski P, Voors AA, Anker SD, et al. ESC guidelines for the diagnosis and treatment of acute and chronic heart failure:the task force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC). Developed with the special contribution of the Heart Failure Association (HFA) of the ESC. Eur J Heart Fail. 2016;18:891–975.
    • (2016) Eur J Heart Fail , vol.18 , pp. 891-975
    • Ponikowski, P.1    Voors, A.A.2    Anker, S.D.3
  • 43
    • 84905702826 scopus 로고    scopus 로고
    • Efficacy and safety of the pulsed infusions of levosimendan in outpatients with advanced heart failure (LevoRep) study: a multicentre randomized trial
    • Altenberger J, Parissis JT, Costard-Jaeckle A, et al. Efficacy and safety of the pulsed infusions of levosimendan in outpatients with advanced heart failure (LevoRep) study:a multicentre randomized trial. Eur J Heart Fail. 2014;16:898–906.
    • (2014) Eur J Heart Fail , vol.16 , pp. 898-906
    • Altenberger, J.1    Parissis, J.T.2    Costard-Jaeckle, A.3
  • 44
    • 20044366544 scopus 로고    scopus 로고
    • Efficacy and safety of intermittent, long-term, concomitant dobutamine and levosimendan infusions in severe heart failure refractory to dobutamine alone
    • Nanas JN, Papazoglou P, Tsagalou EP, et al. Efficacy and safety of intermittent, long-term, concomitant dobutamine and levosimendan infusions in severe heart failure refractory to dobutamine alone. Am J Cardiol. 2005;95:768–771.
    • (2005) Am J Cardiol , vol.95 , pp. 768-771
    • Nanas, J.N.1    Papazoglou, P.2    Tsagalou, E.P.3
  • 45
    • 84865449305 scopus 로고    scopus 로고
    • Comparison of three different regimens of intermittent inotrope infusions for end stage heart failure
    • Bonios MJ, Terrovitis JV, Drakos SG, et al. Comparison of three different regimens of intermittent inotrope infusions for end stage heart failure. Int J Cardiol. 2012;159:225–229.
    • (2012) Int J Cardiol , vol.159 , pp. 225-229
    • Bonios, M.J.1    Terrovitis, J.V.2    Drakos, S.G.3
  • 46
    • 33845228706 scopus 로고    scopus 로고
    • Effects of serial levosimendan infusions on left ventricular performance and plasma biomarkers of myocardial injury and neurohormonal and immune activation in patients with advanced heart failure
    • Parissis JT, Adamopoulos S, Farmakis D, et al. Effects of serial levosimendan infusions on left ventricular performance and plasma biomarkers of myocardial injury and neurohormonal and immune activation in patients with advanced heart failure. Heart. 2006;92:1768–1772.
    • (2006) Heart , vol.92 , pp. 1768-1772
    • Parissis, J.T.1    Adamopoulos, S.2    Farmakis, D.3
  • 47
    • 34548448464 scopus 로고    scopus 로고
    • A 6-month follow-up of intermittent levosimendan administration effect on systolic function, specific activity questionnaire, and arrhythmia in advanced heart failure
    • Mavrogeni S, Giamouzis G, Papadopoulou E, et al. A 6-month follow-up of intermittent levosimendan administration effect on systolic function, specific activity questionnaire, and arrhythmia in advanced heart failure. J Card Fail. 2007;13:556–559.
    • (2007) J Card Fail , vol.13 , pp. 556-559
    • Mavrogeni, S.1    Giamouzis, G.2    Papadopoulou, E.3
  • 48
    • 67749122523 scopus 로고    scopus 로고
    • Assessment of quality of life using three different activity questionnaires in heart failure patients after monthly, intermittent administration of levosimendan during a six-month period
    • Papadopoulou EF, Mavrogeni SI, Dritsas A, et al. Assessment of quality of life using three different activity questionnaires in heart failure patients after monthly, intermittent administration of levosimendan during a six-month period. Hell J Cardiol. 2009;50:269–274.
    • (2009) Hell J Cardiol , vol.50 , pp. 269-274
    • Papadopoulou, E.F.1    Mavrogeni, S.I.2    Dritsas, A.3
  • 49
    • 58149180214 scopus 로고    scopus 로고
    • Repetitive dosing of intravenous levosimendan improves pulmonary hemodynamics in patients with pulmonary hypertension: results of a pilot study
    • Kleber FX, Bollmann T, Borst MM, et al. Repetitive dosing of intravenous levosimendan improves pulmonary hemodynamics in patients with pulmonary hypertension:results of a pilot study. J Clin Pharmacol. 2009;49:109–115.
    • (2009) J Clin Pharmacol , vol.49 , pp. 109-115
    • Kleber, F.X.1    Bollmann, T.2    Borst, M.M.3
  • 50
    • 84870059570 scopus 로고    scopus 로고
    • Intermittent levosimendan infusions in advanced heart failure: favorable effects on left ventricular function, neurohormonal balance, and one-year survival
    • Malfatto G, Della Rosa F, Villani A, et al. Intermittent levosimendan infusions in advanced heart failure:favorable effects on left ventricular function, neurohormonal balance, and one-year survival. J Cardiovasc Pharmacol. 2012;60:450–455.
    • (2012) J Cardiovasc Pharmacol , vol.60 , pp. 450-455
    • Malfatto, G.1    Della Rosa, F.2    Villani, A.3
  • 51
    • 33847787867 scopus 로고    scopus 로고
    • Levosimendan and prostaglandin E1 for uptitration of beta-blockade in patients with refractory, advanced chronic heart failure
    • Berger R, Moertl D, Huelsmann M, et al. Levosimendan and prostaglandin E1 for uptitration of beta-blockade in patients with refractory, advanced chronic heart failure. Eur J Heart Fail. 2007;9:202–208.
    • (2007) Eur J Heart Fail , vol.9 , pp. 202-208
    • Berger, R.1    Moertl, D.2    Huelsmann, M.3
  • 52
    • 43049179359 scopus 로고    scopus 로고
    • Repeated infusions of levosimendan: well tolerated and improves functional capacity in decompensated heart failure—a single-centre experience
    • Parle NM, Thomas MD, Dembo L, et al. Repeated infusions of levosimendan:well tolerated and improves functional capacity in decompensated heart failure—a single-centre experience. Heart Lung Circ. 2008;17:206–210.
    • (2008) Heart Lung Circ , vol.17 , pp. 206-210
    • Parle, N.M.1    Thomas, M.D.2    Dembo, L.3
  • 53
    • 84902796549 scopus 로고    scopus 로고
    • Intermittent levosimendan improves mid-term survival in chronic heart failure patients: meta-analysis of randomized trials
    • Silvetti S, Greco T, Di Prima AL, et al. Intermittent levosimendan improves mid-term survival in chronic heart failure patients:meta-analysis of randomized trials. Clin Res Cardiol. 2014;103:505–513.
    • (2014) Clin Res Cardiol , vol.103 , pp. 505-513
    • Silvetti, S.1    Greco, T.2    Di Prima, A.L.3
  • 54
    • 84862519619 scopus 로고    scopus 로고
    • Dobutamine for patients with severe heart failure: a systematic review and metaanalysis of randomized controlled trials
    • Tacon CL, McCaffrey J, Delaney A. Dobutamine for patients with severe heart failure:a systematic review and metaanalysis of randomized controlled trials. Intensive Care Med. 2012;38:359–367.
    • (2012) Intensive Care Med , vol.38 , pp. 359-367
    • Tacon, C.L.1    McCaffrey, J.2    Delaney, A.3
  • 55
    • 0028351475 scopus 로고
    • Evaluation of the effect of phosphodiesterase inhibitors on mortality in chronic heart failure patients. A meta-analysis
    • Nony P, Boissel JP, Lievre M, et al. Evaluation of the effect of phosphodiesterase inhibitors on mortality in chronic heart failure patients. A meta-analysis. Eur J Clin Pharmacol. 1994;46:191–196.
    • (1994) Eur J Clin Pharmacol , vol.46 , pp. 191-196
    • Nony, P.1    Boissel, J.P.2    Lievre, M.3
  • 56
    • 84958240784 scopus 로고    scopus 로고
    • Long-term intravenous inotropes in low-output terminal heart failure?
    • von Scheidt W, Pauschinger M, Ertl G. Long-term intravenous inotropes in low-output terminal heart failure? Clin Res Cardiol. 2016;105:471–481.
    • (2016) Clin Res Cardiol , vol.105 , pp. 471-481
    • von Scheidt, W.1    Pauschinger, M.2    Ertl, G.3
  • 58
    • 77954159820 scopus 로고    scopus 로고
    • Cardio-renal syndromes: report from the consensus conference of the acute dialysis quality initiative
    • Ronco C, McCullough P, Anker SD, et al. Cardio-renal syndromes:report from the consensus conference of the acute dialysis quality initiative. Eur Heart J. 2010;31:703–711.•• Excellent consensus opinion.
    • (2010) Eur Heart J , vol.31 , pp. 703-711
    • Ronco, C.1    McCullough, P.2    Anker, S.D.3
  • 59
    • 84941939248 scopus 로고    scopus 로고
    • The kidney in heart failure: an update
    • Damman K, Testani JM. The kidney in heart failure:an update. Eur Heart J. 2015;36:1437–1444.
    • (2015) Eur Heart J , vol.36 , pp. 1437-1444
    • Damman, K.1    Testani, J.M.2
  • 60
    • 84929698818 scopus 로고    scopus 로고
    • What physicians need to know about renal function in outpatients with heart failure
    • Waldum-Grevbo B. What physicians need to know about renal function in outpatients with heart failure. Cardiology. 2015;131:130–138.
    • (2015) Cardiology , vol.131 , pp. 130-138
    • Waldum-Grevbo, B.1
  • 61
    • 84866124993 scopus 로고    scopus 로고
    • The role of the kidney in heart failure
    • Metra M, Cotter G, Gheorghiade M, et al. The role of the kidney in heart failure. Eur Heart J. 2012;33:2135–2142.
    • (2012) Eur Heart J , vol.33 , pp. 2135-2142
    • Metra, M.1    Cotter, G.2    Gheorghiade, M.3
  • 62
    • 84864477617 scopus 로고    scopus 로고
    • ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: the task force for the diagnosis and treatment of acute and chronic heart failure 2012 of the European society of cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC
    • McMurray JJ, Adamopoulos S, Anker SD, et al. ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2012:the task force for the diagnosis and treatment of acute and chronic heart failure 2012 of the European society of cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC. Eur J Heart Fail. 2012;14:803–869.
    • (2012) Eur J Heart Fail , vol.14 , pp. 803-869
    • McMurray, J.J.1    Adamopoulos, S.2    Anker, S.D.3
  • 63
    • 36849013485 scopus 로고    scopus 로고
    • Levosimendan improves renal function in patients with acute decompensated heart failure: comparison with dobutamine
    • Yilmaz MB, Yalta K, Yontar C, et al. Levosimendan improves renal function in patients with acute decompensated heart failure:comparison with dobutamine. Cardiovasc Drugs Ther. 2007;21:431–435.
    • (2007) Cardiovasc Drugs Ther , vol.21 , pp. 431-435
    • Yilmaz, M.B.1    Yalta, K.2    Yontar, C.3
  • 64
    • 84875767706 scopus 로고    scopus 로고
    • Effect of levosimendan on estimated glomerular filtration rate in hospitalized patients with decompensated heart failure and renal dysfunction
    • Hou ZQ, Sun ZX, Su CY, et al. Effect of levosimendan on estimated glomerular filtration rate in hospitalized patients with decompensated heart failure and renal dysfunction. Cardiovasc Ther. 2013;31:108–114.
    • (2013) Cardiovasc Ther , vol.31 , pp. 108-114
    • Hou, Z.Q.1    Sun, Z.X.2    Su, C.Y.3
  • 65
    • 84922263005 scopus 로고    scopus 로고
    • Effects of levosimendan on markers of kidney function in patients with acutely decompensated heart failure and renal impairment
    • Jan
    • Rafouli-Stergiou P, Parissis JT, Farmakis D, et al. Effects of levosimendan on markers of kidney function in patients with acutely decompensated heart failure and renal impairment. J Cardiovasc Med (Hagerstown). 2015. published online 2015 Jan31. DOI:10.2459/JCM.0000000000000244
    • (2015) J Cardiovasc Med (Hagerstown)
    • Rafouli-Stergiou, P.1    Parissis, J.T.2    Farmakis, D.3
  • 66
    • 84866142081 scopus 로고    scopus 로고
    • Effect of levosimendan in patients with severe systolic heart failure and worsening renal function
    • Zorlu A, Yucel H, Yontar OC, et al. Effect of levosimendan in patients with severe systolic heart failure and worsening renal function. Arq Bras Cardiol. 2012;98:537–543.
    • (2012) Arq Bras Cardiol , vol.98 , pp. 537-543
    • Zorlu, A.1    Yucel, H.2    Yontar, O.C.3
  • 67
    • 85006356898 scopus 로고    scopus 로고
    • The effects of levosimendan on renal function early after heart transplantation: results from a pilot randomized trial
    • Knezevic I, Poglajen G, Hrovat E, et al. The effects of levosimendan on renal function early after heart transplantation:results from a pilot randomized trial. Clin Transplant. 2014;28:1105–1111.
    • (2014) Clin Transplant , vol.28 , pp. 1105-1111
    • Knezevic, I.1    Poglajen, G.2    Hrovat, E.3
  • 68
  • 69
    • 34547442389 scopus 로고    scopus 로고
    • Levosimendan improves renal function in patients with advanced chronic heart failure awaiting cardiac transplantation
    • Zemljic G, Bunc M, Yazdanbakhsh AP, et al. Levosimendan improves renal function in patients with advanced chronic heart failure awaiting cardiac transplantation. J Card Fail. 2007;13:417–421.
    • (2007) J Card Fail , vol.13 , pp. 417-421
    • Zemljic, G.1    Bunc, M.2    Yazdanbakhsh, A.P.3
  • 70
    • 59049083156 scopus 로고    scopus 로고
    • Comparative effects of levosimendan and dobutamine on right ventricular function in patients with biventricular heart failure
    • Yilmaz MB, Yontar C, Erdem A, et al. Comparative effects of levosimendan and dobutamine on right ventricular function in patients with biventricular heart failure. Heart Vessels. 2009;24:16–21.
    • (2009) Heart Vessels , vol.24 , pp. 16-21
    • Yilmaz, M.B.1    Yontar, C.2    Erdem, A.3
  • 71
    • 84996575043 scopus 로고    scopus 로고
    • Effects of Levosimendan on renal function and renal hemodynamic parameters in patients with acute heart failure
    • Caira C, Brasolin B, Maestrini V, et al. Effects of Levosimendan on renal function and renal hemodynamic parameters in patients with acute heart failure. Eur J Heart Fail Suppl. 2007;6:103.
    • (2007) Eur J Heart Fail Suppl , vol.6 , pp. 103
    • Caira, C.1    Brasolin, B.2    Maestrini, V.3
  • 72
    • 84896921309 scopus 로고    scopus 로고
    • Levosimendan improves renal function in acute decompensated heart failure: possible underlying mechanisms
    • Fedele F, Bruno N, Brasolin B, et al. Levosimendan improves renal function in acute decompensated heart failure:possible underlying mechanisms. Eur J Heart Fail. 2014;16:281–288.
    • (2014) Eur J Heart Fail , vol.16 , pp. 281-288
    • Fedele, F.1    Bruno, N.2    Brasolin, B.3
  • 73
    • 73349086240 scopus 로고    scopus 로고
    • Right ventricular function in myocardial infarction complicated by cardiogenic shock: improvement with levosimendan
    • Russ MA, Prondzinsky R, Carter JM, et al. Right ventricular function in myocardial infarction complicated by cardiogenic shock:improvement with levosimendan. Crit Care Med. 2009;37:3017–3023.
    • (2009) Crit Care Med , vol.37 , pp. 3017-3023
    • Russ, M.A.1    Prondzinsky, R.2    Carter, J.M.3
  • 74
    • 33751160138 scopus 로고    scopus 로고
    • Effects of levosimendan on right ventricular function in patients with advanced heart failure
    • Parissis JT, Paraskevaidis I, Bistola V, et al. Effects of levosimendan on right ventricular function in patients with advanced heart failure. Am J Cardiol. 2006;98:1489–1492.
    • (2006) Am J Cardiol , vol.98 , pp. 1489-1492
    • Parissis, J.T.1    Paraskevaidis, I.2    Bistola, V.3
  • 75
    • 51349149595 scopus 로고    scopus 로고
    • Safety and effectiveness of levosimendan in patients with predominant right heart failure
    • Poelzl G, Zwick RH, Grander W, et al. Safety and effectiveness of levosimendan in patients with predominant right heart failure. Herz. 2008;33:368–373.
    • (2008) Herz , vol.33 , pp. 368-373
    • Poelzl, G.1    Zwick, R.H.2    Grander, W.3
  • 76
    • 40849111905 scopus 로고    scopus 로고
    • Cardiorenal interactions—insights from the ESCAPE trial
    • Nohria A, Hasselblad V, Stebbins A, et al. Cardiorenal interactions—insights from the ESCAPE trial. J Am Coll Cardiol. 2007;51:1268–1274.
    • (2007) J Am Coll Cardiol , vol.51 , pp. 1268-1274
    • Nohria, A.1    Hasselblad, V.2    Stebbins, A.3
  • 77
    • 84960116977 scopus 로고    scopus 로고
    • Repeated or intermittent levosimendan treatment in advanced heart failure: an updated meta-analysis
    • Silvetti S, Nieminen MS. Repeated or intermittent levosimendan treatment in advanced heart failure:an updated meta-analysis. Int J Cardiol. 2016;202:138–143.
    • (2016) Int J Cardiol , vol.202 , pp. 138-143
    • Silvetti, S.1    Nieminen, M.S.2
  • 78
    • 34548594207 scopus 로고    scopus 로고
    • Effects of levosimendan on QoL and emotional stress in advanced heart failure patients
    • Parissis JT, Papadopoulos C, Nikolaou M, et al. Effects of levosimendan on QoL and emotional stress in advanced heart failure patients. Cardiovasc Drugs Ther. 2007;21:263–268.
    • (2007) Cardiovasc Drugs Ther , vol.21 , pp. 263-268
    • Parissis, J.T.1    Papadopoulos, C.2    Nikolaou, M.3
  • 79
    • 80053992114 scopus 로고    scopus 로고
    • Cost-effectiveness of levosimendan in patients with acute heart failure
    • Fedele F, Bruno N, Brasolin B, et al. Cost-effectiveness of levosimendan in patients with acute heart failure. J Cardiovasc Pharmacol. 2011;58:363–366.
    • (2011) J Cardiovasc Pharmacol , vol.58 , pp. 363-366
    • Fedele, F.1    Bruno, N.2    Brasolin, B.3
  • 80
    • 84873718959 scopus 로고    scopus 로고
    • Economic evaluation of levosimendan versus dobutamine for the treatment of acute heart failure in Italy
    • Lucioni C, D’Ambrosi A, Mazzi S, et al. Economic evaluation of levosimendan versus dobutamine for the treatment of acute heart failure in Italy. Adv Ther. 2012;29:1037–1050.
    • (2012) Adv Ther , vol.29 , pp. 1037-1050
    • Lucioni, C.1    D’Ambrosi, A.2    Mazzi, S.3
  • 81
    • 56349153125 scopus 로고    scopus 로고
    • Oral levosimendan in patients with severe chronic heart failure –the PERSIST study
    • Nieminen MS, Cleland JG, Eha J, et al. Oral levosimendan in patients with severe chronic heart failure –the PERSIST study. Eur J Heart Fail. 2008;10:1246–1254.
    • (2008) Eur J Heart Fail , vol.10 , pp. 1246-1254
    • Nieminen, M.S.1    Cleland, J.G.2    Eha, J.3
  • 82
    • 28744446343 scopus 로고    scopus 로고
    • guideline update for the diagnosis and management of chronic heart failure in the adult: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Update the 2001 Guidelines for the Evaluation and Management of Heart Failure): developed in collaboration with the American College of Chest Physicians and the International Society for Heart and Lung Transplantation: endorsed by the Heart Rhythm Society
    • Hunt SA, Abraham WT, Mh C, et al.; ACC/AHA. guideline update for the diagnosis and management of chronic heart failure in the adult:a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Update the 2001 Guidelines for the Evaluation and Management of Heart Failure):developed in collaboration with the American College of Chest Physicians and the International Society for Heart and Lung Transplantation:endorsed by the Heart Rhythm Society. Circulation. 2005;112:e154–e235.• Guideline.
    • (2005) Circulation , vol.112 , pp. e154-e235
    • Hunt, S.A.1    Abraham, W.T.2    Mh, C.3
  • 83
    • 84982764321 scopus 로고    scopus 로고
    • A retrospective population based cohort study of access to specialist palliative care in the last year of life: who is still missing out a decade on?
    • Rosenwax L, Spilsbury K, McNamara BA, et al. A retrospective population based cohort study of access to specialist palliative care in the last year of life:who is still missing out a decade on? BMC Palliat Care. 2016;15:46.
    • (2016) BMC Palliat Care , vol.15 , pp. 46
    • Rosenwax, L.1    Spilsbury, K.2    McNamara, B.A.3
  • 84
    • 84980343461 scopus 로고    scopus 로고
    • Quality of end-of-life care provided to patients with different serious illnesses
    • Wachterman MW, Pilver C, Smith D, et al. Quality of end-of-life care provided to patients with different serious illnesses. JAMA Intern Med. 2016;176:1095–1102.
    • (2016) JAMA Intern Med , vol.176 , pp. 1095-1102
    • Wachterman, M.W.1    Pilver, C.2    Smith, D.3
  • 85
    • 84964324454 scopus 로고    scopus 로고
    • Palliative care in patients with heart failure
    • McIlvennan CK, Allen LA. Palliative care in patients with heart failure. Br Med J. 2016;353:i1010.
    • (2016) Br Med J , vol.353 , pp. i1010
    • McIlvennan, C.K.1    Allen, L.A.2
  • 86
    • 84973550299 scopus 로고    scopus 로고
    • Impact of advance care planning on the care of patients with heart failure: study protocol for a randomized controlled trial
    • Malhotra C, Sim DK, Jaufeerally F, et al. Impact of advance care planning on the care of patients with heart failure:study protocol for a randomized controlled trial. Trials. 2016;17:285.
    • (2016) Trials , vol.17 , pp. 285
    • Malhotra, C.1    Sim, D.K.2    Jaufeerally, F.3
  • 87
    • 84968807212 scopus 로고    scopus 로고
    • Compassionate deactivation of ventricular assist devices in pediatric patients
    • Hollander SA, Axelrod DM, Bernstein D, et al. Compassionate deactivation of ventricular assist devices in pediatric patients. J Heart Lung Transplant. 2016;35:564–567.
    • (2016) J Heart Lung Transplant , vol.35 , pp. 564-567
    • Hollander, S.A.1    Axelrod, D.M.2    Bernstein, D.3
  • 88
    • 85011592584 scopus 로고    scopus 로고
    • How does uncertainty shape patient experience in advanced illness? A secondary analysis of qualitative data
    • Apr
    • Etkind SN, Bristowe K, Bailey K, et al. How does uncertainty shape patient experience in advanced illness? A secondary analysis of qualitative data. Palliat Med. 2016. published online 2016 Apr29. DOI:10.1177/0269216316647610
    • (2016) Palliat Med
    • Etkind, S.N.1    Bristowe, K.2    Bailey, K.3
  • 89
    • 84963985262 scopus 로고    scopus 로고
    • Integrating care across disciplines
    • Blachman NL, Blaum CS. Integrating care across disciplines. Clin Geriatr Med. 2016;32:373–383.
    • (2016) Clin Geriatr Med , vol.32 , pp. 373-383
    • Blachman, N.L.1    Blaum, C.S.2
  • 90
    • 84963812614 scopus 로고    scopus 로고
    • Mortality in a cohort of complex patients with chronic illnesses and multimorbidity: a descriptive longitudinal study
    • Martín-Lesende I, Recalde E, Viviane-Wunderling P, et al. Mortality in a cohort of complex patients with chronic illnesses and multimorbidity:a descriptive longitudinal study. BMC Palliat Care. 2016;15:42.
    • (2016) BMC Palliat Care , vol.15 , pp. 42
    • Martín-Lesende, I.1    Recalde, E.2    Viviane-Wunderling, P.3
  • 91
    • 84991396055 scopus 로고    scopus 로고
    • High satisfaction and low decisional conflict with advance care planning among chronically ill patients with advanced chronic obstructive pulmonary disease or heart failure using an online decision aid_ a pilot study
    • Apr
    • Van Scoy LJ, Green MJ, Dimmock AE, et al. High satisfaction and low decisional conflict with advance care planning among chronically ill patients with advanced chronic obstructive pulmonary disease or heart failure using an online decision aid_ a pilot study. Chronic Illn. 2016;12:227–235. published online 2016 Apr6. DOI:10.1177/1742395316633511
    • (2016) Chronic Illn , vol.12 , pp. 227-235
    • Van Scoy, L.J.1    Green, M.J.2    Dimmock, A.E.3
  • 92
    • 84963825498 scopus 로고    scopus 로고
    • Barriers and facilitators to scaling up outpatient palliative care
    • Bekelman DB, Rabin BA, Nowels CT, et al. Barriers and facilitators to scaling up outpatient palliative care. J Palliat Med. 2016;19:456–459.
    • (2016) J Palliat Med , vol.19 , pp. 456-459
    • Bekelman, D.B.1    Rabin, B.A.2    Nowels, C.T.3
  • 93
    • 84961711918 scopus 로고    scopus 로고
    • Effects of a transitional palliative care model on patients with end-stage heart failure: a randomized controlled trial
    • Wong FK, Ng AY, Lee PH, et al. Effects of a transitional palliative care model on patients with end-stage heart failure:a randomized controlled trial. Heart. 2016;102:1100–1108.
    • (2016) Heart , vol.102 , pp. 1100-1108
    • Wong, F.K.1    Ng, A.Y.2    Lee, P.H.3
  • 94
    • 84959314493 scopus 로고    scopus 로고
    • ‘Who is on your health-care team?’ Asking individuals with heart failure about care team membership and roles
    • Feb
    • LaDonna KA, Bates J, Tait GR, et al. ‘Who is on your health-care team?’ Asking individuals with heart failure about care team membership and roles. Health Expect. 2016. published online 29Feb 2016. DOI:10.1111/hex.12447
    • (2016) Health Expect
    • LaDonna, K.A.1    Bates, J.2    Tait, G.R.3
  • 95
    • 84973320548 scopus 로고    scopus 로고
    • Phase 2 randomised controlled trial and feasibility study of future care planning in patients with advanced heart disease
    • Denvir MA, Cudmore S, Highet G, et al. Phase 2 randomised controlled trial and feasibility study of future care planning in patients with advanced heart disease. Sci Rep. 2016;6:24619.
    • (2016) Sci Rep , vol.6 , pp. 24619
    • Denvir, M.A.1    Cudmore, S.2    Highet, G.3
  • 96
    • 84982811697 scopus 로고    scopus 로고
    • Building consensus for provision of breathlessness rehabilitation for patients with chronic obstructive pulmonary disease and chronic heart failure
    • Man WD, Chowdhury F, Taylor RS, et al. Building consensus for provision of breathlessness rehabilitation for patients with chronic obstructive pulmonary disease and chronic heart failure. Chron Respir Dis. 2016;13:229–239.
    • (2016) Chron Respir Dis , vol.13 , pp. 229-239
    • Man, W.D.1    Chowdhury, F.2    Taylor, R.S.3
  • 97
    • 73949098138 scopus 로고    scopus 로고
    • Palliative care in the treatment of advanced heart failure
    • Adler ED, Goldfinger JZ, Kalman J, et al. Palliative care in the treatment of advanced heart failure. Circulation. 2009;120:2597–2606.
    • (2009) Circulation , vol.120 , pp. 2597-2606
    • Adler, E.D.1    Goldfinger, J.Z.2    Kalman, J.3
  • 98
    • 84859739692 scopus 로고    scopus 로고
    • Decision making in advanced heart failure: a scientific statement from the American Heart Association
    • Allen LA, Stevenson LW, Grady KL, et al. Decision making in advanced heart failure:a scientific statement from the American Heart Association. Circulation. 2012;125:1928–1952.
    • (2012) Circulation , vol.125 , pp. 1928-1952
    • Allen, L.A.1    Stevenson, L.W.2    Grady, K.L.3
  • 100
    • 84875617415 scopus 로고    scopus 로고
    • Patients’ family satisfaction with needs met at the medical intensive care unit
    • Khalaila R. Patients’ family satisfaction with needs met at the medical intensive care unit. J Adv Nurs. 2013;69:1172–1182.
    • (2013) J Adv Nurs , vol.69 , pp. 1172-1182
    • Khalaila, R.1
  • 101
    • 84922008960 scopus 로고    scopus 로고
    • The changing role of palliative care in the ICU
    • Aslakson RA, Curtis JR, Nelson JE. The changing role of palliative care in the ICU. Crit Care Med. 2014;42:2418–2428.
    • (2014) Crit Care Med , vol.42 , pp. 2418-2428
    • Aslakson, R.A.1    Curtis, J.R.2    Nelson, J.E.3
  • 102
    • 62449339299 scopus 로고    scopus 로고
    • Health care costs in the last week of life: associations with end-of-life conversations
    • Zhang B, Wright AA, Huskamp HA, et al. Health care costs in the last week of life:associations with end-of-life conversations. Arch Intern Med. 2009;169:480–488.
    • (2009) Arch Intern Med , vol.169 , pp. 480-488
    • Zhang, B.1    Wright, A.A.2    Huskamp, H.A.3
  • 103
    • 84877055893 scopus 로고    scopus 로고
    • [Definitions, decision-making and documentation in end of life situations in the intensive care unit]
    • German
    • Friesenecker B, Fruhwald S, Hasibeder W, et al. [Definitions, decision-making and documentation in end of life situations in the intensive care unit]. Anästhesiol Intensivmed Notfallmed Schmerzther. 2013;48:216–223. German.
    • (2013) Anästhesiol Intensivmed Notfallmed Schmerzther , vol.48 , pp. 216-223
    • Friesenecker, B.1    Fruhwald, S.2    Hasibeder, W.3
  • 104
    • 0037716612 scopus 로고    scopus 로고
    • The use of opioids and sedatives at the end of life
    • Sykes N, Thorns A. The use of opioids and sedatives at the end of life. Lancet Oncol. 2003;4:312–318.
    • (2003) Lancet Oncol , vol.4 , pp. 312-318
    • Sykes, N.1    Thorns, A.2
  • 105
    • 84964632088 scopus 로고    scopus 로고
    • Is regular systemic opioid analgesia associated with shorter survival in adult patients with cancer? A systematic literature review
    • Boland JW, Ziegler L, Boland EG, et al. Is regular systemic opioid analgesia associated with shorter survival in adult patients with cancer? A systematic literature review. Pain. 2015;156:2152–2163.
    • (2015) Pain , vol.156 , pp. 2152-2163
    • Boland, J.W.1    Ziegler, L.2    Boland, E.G.3
  • 106
    • 84867201246 scopus 로고    scopus 로고
    • Investigating pain in heart failure patients: the pain assessment, incidence, and nature in heart failure (PAIN-HF) study
    • Goodlin SJ, Wingate S, Albert NM, et al. Investigating pain in heart failure patients:the pain assessment, incidence, and nature in heart failure (PAIN-HF) study. J Card Fail. 2012;18:776–783.
    • (2012) J Card Fail , vol.18 , pp. 776-783
    • Goodlin, S.J.1    Wingate, S.2    Albert, N.M.3
  • 107
    • 84908372248 scopus 로고    scopus 로고
    • The palliative care in heart failure trial: rationale and design
    • Mentz J, Tulsky JA, Granger BB, et al. The palliative care in heart failure trial:rationale and design. Am Heart J. 2014;168:645–651.
    • (2014) Am Heart J , vol.168 , pp. 645-651
    • Mentz, J.1    Tulsky, J.A.2    Granger, B.B.3
  • 108
    • 84958599913 scopus 로고    scopus 로고
    • Application of transformational leadership principles in the development and integration of palliative care within an advanced heart failure program
    • George S, Leasure AR. Application of transformational leadership principles in the development and integration of palliative care within an advanced heart failure program. Dimens Crit Care Nurs. 2016;35:59–65.
    • (2016) Dimens Crit Care Nurs , vol.35 , pp. 59-65
    • George, S.1    Leasure, A.R.2
  • 109
    • 84979781521 scopus 로고    scopus 로고
    • Symptom clusters and quality of life among patients with advanced heart failure
    • Yu DS, Chan HY, Leung DY, et al. Symptom clusters and quality of life among patients with advanced heart failure. J Geriatr Cardiol. 2016;13:408–414.
    • (2016) J Geriatr Cardiol , vol.13 , pp. 408-414
    • Yu, D.S.1    Chan, H.Y.2    Leung, D.Y.3
  • 110
    • 84977277196 scopus 로고    scopus 로고
    • Randomized, controlled trial of an advance care planning video decision support tool for patients with advanced heart failure
    • El-Jawahri A, Paasche-Orlow MK, Matlock D, et al. Randomized, controlled trial of an advance care planning video decision support tool for patients with advanced heart failure. Circulation. 2016;134:52–60.
    • (2016) Circulation , vol.134 , pp. 52-60
    • El-Jawahri, A.1    Paasche-Orlow, M.K.2    Matlock, D.3
  • 111
    • 85029223416 scopus 로고    scopus 로고
    • Quality of life in patients receiving telemedicine enhanced chronic heart failure disease management: a meta-analysis
    • Jul
    • Knox L, Rahman RJ, Beedie C. Quality of life in patients receiving telemedicine enhanced chronic heart failure disease management:a meta-analysis. J Telemed Telecare. 2016. published online 2016 Jul22. pii:1357633X16660418.
    • (2016) J Telemed Telecare
    • Knox, L.1    Rahman, R.J.2    Beedie, C.3
  • 112
    • 84977261234 scopus 로고    scopus 로고
    • Telerehabilitation in heart failure patients: the evidence and the pitfalls
    • Piotrowicz E, Piepoli MF, Jaarsma T, et al. Telerehabilitation in heart failure patients:the evidence and the pitfalls. Int J Cardiol. 2016;220:408–413.
    • (2016) Int J Cardiol , vol.220 , pp. 408-413
    • Piotrowicz, E.1    Piepoli, M.F.2    Jaarsma, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.