Recording of hospitalizations for acute exacerbations of COPD in UK electronic health care records

Clinical Epidemiology

Volumn 8, Issue , 2016, Pages 771-782

  Rothnie, Kieran J ^a,b   Mullerova, Hana ^c   Thomas, Sara L ^b   Chandan, Joht S ^d   Smeeth, Liam ^b   Hurst, John R ^d   Davis, Kourtney ^c   Quint, Jennifer K ^a,b  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^c GLAXOSMITHKLINE   (United Kingdom)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Cause specific hospitalization; COPD; Hospitalization; Linked data; Validation

Indexed keywords

ADULT; AGED; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; DISEASE EXACERBATION; DYSPNEA; ELECTRONIC HEALTH RECORD; FEMALE; HEALTH CARE UTILIZATION; HOSPITAL DISCHARGE; HOSPITALIZATION; HUMAN; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; PREDICTIVE VALUE; PRIMARY MEDICAL CARE; SENSITIVITY ANALYSIS; SMOKING; UNITED KINGDOM;

EID: 84996490850     PISSN: None     EISSN: 11791349     Source Type: Journal    
DOI: 10.2147/clep.s117867     Document Type: Article

References (25)

1. Shahab L, Jarvis MJ, Britton J, West R. Prevalence, diagnosis and relation to tobacco dependence of chronic obstructive pulmonary disease in a nationally representative population sample. Thorax. 2006;61(12):1043-1047. doi: 10.1136/thx.2006.064410.
2. Invisible Lives. Chronic Obstructive Pulmonary Disease (COPD)—finding the missing millions. London, UK: British Lung Foundation; 2007.
3. Donaldson GC, Seemungal TAR, Bhowmik A, Wedzicha JA. Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease. Thorax. 2002;57(10):847-852. doi:10.1136/thorax.57.10.847.
4. Miravitlles M, Ferrer M, Pont A, et al. Effect of exacerbations on quality of life in patients with chronic obstructive pulmonary disease: a 2 year follow up study. Thorax. 2004;59(5):387-395. doi:10.1136/thx.2003.008730.
5. Schmidt SA, Johansen MB, Olsen M, et al. The impact of exacerbation frequency on mortality following acute exacerbations of COPD: a registry-based cohort study. BMJOpen. 2014;4(12):e006720. doi:10.1136/bmjopen-2014-006720.
6. Suissa S, Dell’Aniello S, Ernst P. Long-term natural history of chronic obstructive pulmonary disease: severe exacerbations and mortality. Thorax. 2012;67(11):957-963. doi:10.1136/thoraxjnl-2011-201518.
7. Groenewegen KH, Schols AM, Wouters EF. Mortality and mortality-related factors after hospitalization for acute exacerbation of COPD. Chest. 2003;124(2):459-467. doi: http://dx.doi.org/10.1378/chest.1242.459.
8. Healthcare commission. Clearing the Air: A national study of chronic obstructive pulmonary disease. Healthcare Commission; 2006.
9. van Staa TP, Dyson L, McCann G, et al. The opportunities and challenges of pragmatic point-of-care randomised trials using routinely collected electronic records: evaluations of two exemplar trials. Health Technol Assess. 2014;18(43). doi:10.3310/hta18430.
10. Herrett E, Thomas SL, Schoonen WM, Smeeth L, Hall AJ. Validation and validity of diagnoses in the general practice research database: a systematic review. Br J Clin Pharmacol. 2010;69(1):4-14. doi:10.1111/j.1365-2125.2009.03537.x.
11. Baker R, Tata LJ, Kendrick D, Orton E. Identification of incident poisoning, fracture and burn events using linked primary care, secondary care and mortality data from England: implications for research and surveillance. InjPrev. 2016;22(1):59-67. doi:10.1136/injuryprev-2015-041561.
12. Crooks CJ, Card TR, West J. Defining upper gastrointestinal bleeding from linked primary and secondary care data and the effect on occurrence and 28 day mortality. BMC Health Serv Res. 2012;12(1):1-9. doi:10.1186/1472-6963-12-392.
13. Herrett E, Shah AD, Boggon R, et al. Completeness and diagnostic validity of recording acute myocardial infarction events in primary care, hospital care, disease registry, and national mortality records: cohort study. BMJ. 2013;346. doi: 10.1136/bmj.f2350.
14. Postma DS, Roche N, Colice G, et al. Comparing the effectiveness of small-particle versus large-particle inhaled corticosteroid in COPD. Int JChron ObstructPulmonDis. 2014;9:1163-1186. doi:10.2147/COPD.S68289.
15. Punekar YS, Wurst K, Shukla A. Resource use and costs up to two years post diagnosis among newly diagnosed copd patients in the UK primary care setting: a retrospective cohort study. COPD. 2015;12(3):271-280. doi: 10.3109/15412555.2014.933953.
16. Dhamane AD, Moretz C, Zhou Y, et al. COPD exacerbation frequency and its association with health care resource utilization and costs. Int J Chron Obstruct Pulmon Dis. 2015;10:2609-2618. doi:10.2147/COPD.S90148.
17. Raluy-Callado M, Lambrelli D, MacLachlan S, Khalid JM. Epidemiology, severity, and treatment of chronic obstructive pulmonary disease in the United Kingdom by GOLD 2013. Int J Chron Obstruct Pulmon Dis. 2015;10:925-937.
18. Herrett E, Gallagher AM, Bhaskaran K, et al. Data Resource Profile: Clinical Practice Research Datalink (CPRD). Int J Epidemiol. 2015;44(3):827-836. doi: 10.1093/ije/dyv098.
19. Hospital Episodes Statistics, 2016. Available from: http://www.hsdc.gov.uk/hes.
20. Quint JK, Mullerova H, DiSantostefano RL, et al. Validation of chronic obstructive pulmonary disease recording in the Clinical Practice Research Datalink (CPRD-GOLD). BMJ Open. 2014;4(7):e005540. doi: 10.1136/bmjopen-2014-005540.
21. Rothnie KJ, Mullerova H, Hurst JR, et al. Validation of the recording of acute exacerbations of COPD in UK primary care electronic healthcare records. PLoS one. 2016;11(3):e0151357. doi:10.1371/journal.pone.0151357.
22. Mullerova H, Maselli DJ, Locantore N, et al. Hospitalized exacerbations of COPD: risk factors and outcomes in the ECLIPSE Cohort. Chest. 2015;147(4):999-1007. doi: http://dx.doi.org/10.1378/chest.14-0655.
23. Millett ER, Quint JK, De Stavola BL, Smeeth L, Thomas SL. Improved incidence estimates from linked vs. stand-alone electronic health records. J Clin Epidemiol. doi: http://dx.doi.org/10.1016/j.jclinepi.2016.01.005.
24. Meropol SB, Metlay JP Accuracy of pneumonia hospital admissions in a primary care electronic medical record database. Pharmacoepidemiol DrugSaf. 2012;21(6):659-665. doi: 10.1002/pds.3207.PubMedPMID: PMC3371176.
25. Hardelid P, Rait G, Gilbert R, Petersen I. Recording of influenza-like illness in UK primary care 1995-2013: cohort study. PLoS one. 2015; 10(9):e0138659. doi: 10.1371/journal.pone.0138659.