-
1
-
-
84878901004
-
Chemotherapy in metastatic renal cell carcinoma today? A systematic review
-
Buti S, Bersanelli M, Sikokis A, Maines F, Facchinetti F, Bria E, et al. Chemotherapy in metastatic renal cell carcinoma today? A systematic review. Anticancer Drugs 2013;24:535-54.
-
(2013)
Anticancer Drugs
, vol.24
, pp. 535-554
-
-
Buti, S.1
Bersanelli, M.2
Sikokis, A.3
Maines, F.4
Facchinetti, F.5
Bria, E.6
-
2
-
-
0028929682
-
Results of treatment of 255 patients with metastatic renal cell carcinoma who received high-dose recombinant interleukin-2 therapy
-
Fyfe G, Fisher RI, Rosenberg SA, Sznol M, Parkinson DR, Louie AC. Results of treatment of 255 patients with metastatic renal cell carcinoma who received high-dose recombinant interleukin-2 therapy. J Clin Oncol 1995; 13:688-96.
-
(1995)
J Clin Oncol
, vol.13
, pp. 688-696
-
-
Fyfe, G.1
Fisher, R.I.2
Rosenberg, S.A.3
Sznol, M.4
Parkinson, D.R.5
Louie, A.C.6
-
3
-
-
84899679988
-
Randomized phase III trial of temsirolimus versus sorafenib as second-line therapy after sunitinib in patients with metastatic renal cell carcinoma
-
Hutson TE, Escudier B, Esteban E, Bjarnason GA, Lim HY, Pittman KB, et al. Randomized phase III trial of temsirolimus versus sorafenib as second-line therapy after sunitinib in patients with metastatic renal cell carcinoma. J Clin Oncol 2014;32:760-7.
-
(2014)
J Clin Oncol
, vol.32
, pp. 760-767
-
-
Hutson, T.E.1
Escudier, B.2
Esteban, E.3
Bjarnason, G.A.4
Lim, H.Y.5
Pittman, K.B.6
-
4
-
-
77956227464
-
Phase 3 trial of everolimus for metastatic renal cell carcinoma: Final results and analysis of prognostic factors
-
Motzer RJ, Escudier B, Oudard S, Hutson TE, Porta C, Bracarda S, et al. Phase 3 trial of everolimus for metastatic renal cell carcinoma: final results and analysis of prognostic factors. Cancer 2010;116:4256-65.
-
(2010)
Cancer
, vol.116
, pp. 4256-4265
-
-
Motzer, R.J.1
Escudier, B.2
Oudard, S.3
Hutson, T.E.4
Porta, C.5
Bracarda, S.6
-
5
-
-
84896713052
-
Dovitinib versus sorafenib for third-line targeted treatment of patients with metastatic renal cell carcinoma: An open-label, randomised phase 3 trial
-
Motzer RJ, Porta C, Vogelzang NJ, Sternberg CN, Szczylik C, Zolnierek J, et al. Dovitinib versus sorafenib for third-line targeted treatment of patients with metastatic renal cell carcinoma: an open-label, randomised phase 3 trial. Lancet Oncol 2014;15:286-96.
-
(2014)
Lancet Oncol
, vol.15
, pp. 286-296
-
-
Motzer, R.J.1
Porta, C.2
Vogelzang, N.J.3
Sternberg, C.N.4
Szczylik, C.5
Zolnierek, J.6
-
6
-
-
84876974877
-
Axitinib versus sorafenib as second-line treatment for advanced renal cell carcinoma: Overall survival analysis and updated results from a randomised phase 3 trial
-
Motzer RJ, Escudier B, Tomczak P, Hutson TE, Michaelson MD, Negrier S, et al. Axitinib versus sorafenib as second-line treatment for advanced renal cell carcinoma: overall survival analysis and updated results from a randomised phase 3 trial. Lancet Oncol 2013;14:552-62.
-
(2013)
Lancet Oncol
, vol.14
, pp. 552-562
-
-
Motzer, R.J.1
Escudier, B.2
Tomczak, P.3
Hutson, T.E.4
Michaelson, M.D.5
Negrier, S.6
-
7
-
-
84890980389
-
Breathing new life into immunotherapy: Review of melanoma, lung and kidney cancer
-
Drake CG, Lipson EJ, Brahmer JR. Breathing new life into immunotherapy: review of melanoma, lung and kidney cancer. Nat Rev Clin Oncol 2014; 11:24-37.
-
(2014)
Nat Rev Clin Oncol
, vol.11
, pp. 24-37
-
-
Drake, C.G.1
Lipson, E.J.2
Brahmer, J.R.3
-
8
-
-
84979860405
-
PD-1 blockade in renal cell carcinoma: To equilibrium and beyond
-
Harshman LC, Drake CG, Choueiri TK. PD-1 blockade in renal cell carcinoma: to equilibrium and beyond. Cancer Immunol Res 2014;2: 1132-41.
-
(2014)
Cancer Immunol Res
, vol.2
, pp. 1132-1141
-
-
Harshman, L.C.1
Drake, C.G.2
Choueiri, T.K.3
-
9
-
-
84858766182
-
The blockade of immune checkpoints in cancer immunotherapy
-
Pardoll DM. The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer 2012;12:252-64.
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 252-264
-
-
Pardoll, D.M.1
-
10
-
-
77954899030
-
Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: Safety, clinical activity, pharmacodynamics, and immunologic correlates
-
Brahmer JR, Drake CG, Wollner I, Powderly JD, Picus J, Sharfman WH, et al. Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates. J Clin Oncol 2010;28:3167-75.
-
(2010)
J Clin Oncol
, vol.28
, pp. 3167-3175
-
-
Brahmer, J.R.1
Drake, C.G.2
Wollner, I.3
Powderly, J.D.4
Picus, J.5
Sharfman, W.H.6
-
11
-
-
84880706331
-
Survival, safety, and response duration results of nivolumab (Anti-PD-1; BMS-936558; ONO-4538) in a phase I trial in patients with previously treated metastatic renal cell carcinoma (mRCC): Long-term patient follow-up
-
Abstr nr 4514
-
Drake CG, McDermott DF, Sznol M, Choueiri TK, Kluger HM, Powderly JD, et al. Survival, safety, and response duration results of nivolumab (Anti-PD-1; BMS-936558; ONO-4538) in a phase I trial in patients with previously treated metastatic renal cell carcinoma (mRCC): Long-term patient follow-up. J Clin Oncol 2013;31(suppl). Abstr nr 4514.
-
(2013)
J Clin Oncol
, vol.31
-
-
Drake, C.G.1
McDermott, D.F.2
Sznol, M.3
Choueiri, T.K.4
Kluger, H.M.5
Powderly, J.D.6
-
12
-
-
84929572937
-
Nivolumab for metastatic renal cell carcinoma: Results of a randomized phase II trial
-
Motzer RJ, Rini BI, McDermott DF, Redman BG, Kuzel TM, Harrison MR, et al. Nivolumab for metastatic renal cell carcinoma: results of a randomized phase II trial. J Clin Oncol 2014;33:1430-7.
-
(2014)
J Clin Oncol
, vol.33
, pp. 1430-1437
-
-
Motzer, R.J.1
Rini, B.I.2
McDermott, D.F.3
Redman, B.G.4
Kuzel, T.M.5
Harrison, M.R.6
-
13
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian SL, Hodi FS, Brahmer JR, Gettinger SN, Smith DC, McDermott DF, et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med 2012;366:2443-54.
-
(2012)
N Engl J Med
, vol.366
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
Gettinger, S.N.4
Smith, D.C.5
McDermott, D.F.6
-
14
-
-
84898973055
-
Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab
-
Topalian SL, Sznol M, McDermott DF, Kluger HM, Carvajal RD, Sharfman WH, et al. Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab. J Clin Oncol 2014;32:1020-30.
-
(2014)
J Clin Oncol
, vol.32
, pp. 1020-1030
-
-
Topalian, S.L.1
Sznol, M.2
McDermott, D.F.3
Kluger, H.M.4
Carvajal, R.D.5
Sharfman, W.H.6
-
15
-
-
84929361060
-
Survival, durable response, and long-term safety in patients with previously treated advanced renal cell carcinoma receiving nivolumab
-
McDermott DF, Drake CG, Sznol M, Choueiri TK, Powderly JD, Smith DC, et al. Survival, durable response, and long-term safety in patients with previously treated advanced renal cell carcinoma receiving nivolumab. J Clin Oncol 2015;33:2013-20.
-
(2015)
J Clin Oncol
, vol.33
, pp. 2013-2020
-
-
McDermott, D.F.1
Drake, C.G.2
Sznol, M.3
Choueiri, T.K.4
Powderly, J.D.5
Smith, D.C.6
-
16
-
-
84946607195
-
Nivolumab versus everolimus in advanced renal-cell carcinoma
-
Motzer RJ, Escudier B, McDermott DF, George S, Hammers HJ, Srinivas S, et al. Nivolumab versus everolimus in advanced renal-cell carcinoma. N Engl J Med 2015;373:1803-13.
-
(2015)
N Engl J Med
, vol.373
, pp. 1803-1813
-
-
Motzer, R.J.1
Escudier, B.2
McDermott, D.F.3
George, S.4
Hammers, H.J.5
Srinivas, S.6
-
17
-
-
84864024223
-
Circulating biomarkers in advanced renal cell carcinoma: Clinical applications
-
Hernandez-Yanez M, Heymach JV, Zurita AJ. Circulating biomarkers in advanced renal cell carcinoma: clinical applications. Curr Oncol Rep 2012;14:221-9.
-
(2012)
Curr Oncol Rep
, vol.14
, pp. 221-229
-
-
Hernandez-Yanez, M.1
Heymach, J.V.2
Zurita, A.J.3
-
18
-
-
77958012775
-
Gene signature in melanoma associated with clinical activity: A potential clue to unlock cancer immunotherapy
-
Gajewski TF, Louahed J, Brichard VG. Gene signature in melanoma associated with clinical activity: a potential clue to unlock cancer immunotherapy. Cancer J 2010;16:399-403.
-
(2010)
Cancer J
, vol.16
, pp. 399-403
-
-
Gajewski, T.F.1
Louahed, J.2
Brichard, V.G.3
-
19
-
-
84886698315
-
Innate and adaptive immune cells in the tumor microenvironment
-
Gajewski TF, Schreiber H, Fu YX. Innate and adaptive immune cells in the tumor microenvironment. Nat Immunol 2013;14:1014-22.
-
(2013)
Nat Immunol
, vol.14
, pp. 1014-1022
-
-
Gajewski, T.F.1
Schreiber, H.2
Fu, Y.X.3
-
20
-
-
84903172686
-
Immune cells in the melanoma microenvironment hold information for prediction of the risk of recurrence and response to treatment
-
Camisaschi C, Vallacchi V, Castelli C, Rivoltini L, Rodolfo M. Immune cells in the melanoma microenvironment hold information for prediction of the risk of recurrence and response to treatment. Expert Rev Mol Diagn 2014;14:643-6.
-
(2014)
Expert Rev Mol Diagn
, vol.14
, pp. 643-646
-
-
Camisaschi, C.1
Vallacchi, V.2
Castelli, C.3
Rivoltini, L.4
Rodolfo, M.5
-
21
-
-
84862769116
-
An immune-active tumor microenvironment favors clinical response to ipilimumab
-
Ji RR, Chasalow SD, Wang L, Hamid O, Schmidt H, Cogswell J, et al. An immune-active tumor microenvironment favors clinical response to ipilimumab. Cancer Immunol Immunother 2012;61:1019-31.
-
(2012)
Cancer Immunol Immunother
, vol.61
, pp. 1019-1031
-
-
Ji, R.R.1
Chasalow, S.D.2
Wang, L.3
Hamid, O.4
Schmidt, H.5
Cogswell, J.6
-
22
-
-
84920956732
-
PD-1 blockade induces responses by inhibiting adaptive immune resistance
-
Tumeh PC, Harview CL, Yearley JH, Shintaku IP, Taylor EJ, Robert L, et al. PD-1 blockade induces responses by inhibiting adaptive immune resistance. Nature 2014;515:568-71.
-
(2014)
Nature
, vol.515
, pp. 568-571
-
-
Tumeh, P.C.1
Harview, C.L.2
Yearley, J.H.3
Shintaku, I.P.4
Taylor, E.J.5
Robert, L.6
-
23
-
-
77952337834
-
Preoperative CTLA-4 blockade: Tolerability and immune monitoring in the setting of a presurgical clinical trial
-
Carthon BC, Wolchok JD, Yuan J, Kamat A, Ng Tang DS, Sun J, et al. Preoperative CTLA-4 blockade: tolerability and immune monitoring in the setting of a presurgical clinical trial. Clin Cancer Res 2010;16:2861-71.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 2861-2871
-
-
Carthon, B.C.1
Wolchok, J.D.2
Yuan, J.3
Kamat, A.4
Ng Tang, D.S.5
Sun, J.6
-
24
-
-
84887017053
-
CXCR3/CCR5 pathways in metastatic melanoma patients treated with adoptive therapy and interleukin-2
-
Bedognetti D, Spivey TL, Zhao Y, Uccellini L, Tomei S, Dudley ME, et al. CXCR3/CCR5 pathways in metastatic melanoma patients treated with adoptive therapy and interleukin-2. Br J Cancer 2013;109:2412-23.
-
(2013)
Br J Cancer
, vol.109
, pp. 2412-2423
-
-
Bedognetti, D.1
Spivey, T.L.2
Zhao, Y.3
Uccellini, L.4
Tomei, S.5
Dudley, M.E.6
-
25
-
-
84907498833
-
Survival, response duration, and activity by BRAF mutation (MT) status of nivolumab (NIVO, anti-PD-1, BMS-936558, ONO-4538) and ipilimumab (IPI) concurrent therapy in advanced melanoma (MEL)
-
Abstr nr LBA9003
-
Sznol M, Kluger HM, Callahan MK, Postow MA, Gordon RA, Segel NH, et al. Survival, response duration, and activity by BRAF mutation (MT) status of nivolumab (NIVO, anti-PD-1, BMS-936558, ONO-4538) and ipilimumab (IPI) concurrent therapy in advanced melanoma (MEL). J Clin Oncol 2014;32(suppl). Abstr nr LBA9003.
-
(2014)
J Clin Oncol
, vol.32
-
-
Sznol, M.1
Kluger, H.M.2
Callahan, M.K.3
Postow, M.A.4
Gordon, R.A.5
Segel, N.H.6
-
26
-
-
12344280017
-
Summaries of affymetrix gene chip probe level data
-
Irizarry RA, Bolstad BM, Collin F, Cope LM, Hobbs B, Speed TP. Summaries of Affymetrix Gene Chip probe level data. Nucleic Acids Res 2003;31:e15.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. e15
-
-
Irizarry, R.A.1
Bolstad, B.M.2
Collin, F.3
Cope, L.M.4
Hobbs, B.5
Speed, T.P.6
-
27
-
-
29144535372
-
Evolving gene/transcript definitions significantly alter the interpretation of gene chip data
-
Dai M, Wang P, Boyd AD, Kostov G, Athey B, Jones EG, et al. Evolving gene/transcript definitions significantly alter the interpretation of Gene Chip data. Nucleic Acids Res 2005;33:e175.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. e175
-
-
Dai, M.1
Wang, P.2
Boyd, A.D.3
Kostov, G.4
Athey, B.5
Jones, E.G.6
-
29
-
-
0001072895
-
The use of confidence or fiducial limits illustrated in the case of the binomial
-
Clopper CJ, Pearson ES. The use of confidence or fiducial limits illustrated in the case of the binomial. Biometrika 1934;26:404-13.
-
(1934)
Biometrika
, vol.26
, pp. 404-413
-
-
Clopper, C.J.1
Pearson, E.S.2
-
30
-
-
0002429117
-
A confidence interval for the median survival time
-
Brookmeyer R, Crowley J. A confidence interval for the median survival time. Biometrics 1982;38:29-41.
-
(1982)
Biometrics
, vol.38
, pp. 29-41
-
-
Brookmeyer, R.1
Crowley, J.2
-
32
-
-
84995934015
-
Gene set enrichment analysis
-
Nikolsky Y, Bryant J editors. New York, NY: Humana Press
-
Tilford CA, Siemer NO. Gene set enrichment analysis. In: Nikolsky Y, Bryant J editors. Protein networks and pathways. New York, NY: Humana Press; 2009. p. 99-122.
-
(2009)
Protein Networks and Pathways
, pp. 99-122
-
-
Tilford, C.A.1
Siemer, N.O.2
-
33
-
-
21344446363
-
Immune response in silico (IRIS): Immune-specific genes identified from a compendium of microarray expression data
-
Abbas AR, Baldwin D, Ma Y, Ouyang W, Gurney A, Martin F, et al. Immune response in silico (IRIS): immune-specific genes identified from a compendium of microarray expression data. Genes Immun 2005;6: 319-31.
-
(2005)
Genes Immun
, vol.6
, pp. 319-331
-
-
Abbas, A.R.1
Baldwin, D.2
Ma, Y.3
Ouyang, W.4
Gurney, A.5
Martin, F.6
-
34
-
-
46749152178
-
A modular analysis framework for blood genomics studies: Application to systemic lupus erythematosus
-
Chaussabel D, Quinn C, Shen J, Patel P, Glaser C, Baldwin N, et al. A modular analysis framework for blood genomics studies: application to systemic lupus erythematosus. Immunity 2008;29:150-64.
-
(2008)
Immunity
, vol.29
, pp. 150-164
-
-
Chaussabel, D.1
Quinn, C.2
Shen, J.3
Patel, P.4
Glaser, C.5
Baldwin, N.6
-
35
-
-
33745587776
-
Favorable prognosis of renal cell carcinoma with increased expression of chemokines associated with a Th1-type immune response
-
Kondo T, Nakazawa H, Ito F, Hashimoto Y, Osaka Y, Futatsuyama K, et al. Favorable prognosis of renal cell carcinoma with increased expression of chemokines associated with a Th1-type immune response. Cancer Sci 2006;97:780-6.
-
(2006)
Cancer Sci
, vol.97
, pp. 780-786
-
-
Kondo, T.1
Nakazawa, H.2
Ito, F.3
Hashimoto, Y.4
Osaka, Y.5
Futatsuyama, K.6
-
36
-
-
0034793679
-
Sequential tumor biopsies in early phase clinical trials of anticancer agents for pharmacodynamic evaluation
-
Dowlati A, Haaga J, Remick SC, Spiro TP, Gerson SL, Liu L, et al. Sequential tumor biopsies in early phase clinical trials of anticancer agents for pharmacodynamic evaluation. Clin Cancer Res 2001;7:2971-6.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 2971-2976
-
-
Dowlati, A.1
Haaga, J.2
Remick, S.C.3
Spiro, T.P.4
Gerson, S.L.5
Liu, L.6
-
37
-
-
0033561638
-
Gene expression and production of the monokine induced by IFN-gamma (MIG), IFN-inducible T cell alpha chemoattractant (I-TAC), and IFNgamma-inducible protein-10 (IP-10) chemokines by human neutrophils
-
Gasperini S, Marchi M, Calzetti F, Laudanna C, Vicentini L, Olsen H, et al. Gene expression and production of the monokine induced by IFN-gamma (MIG), IFN-inducible T cell alpha chemoattractant (I-TAC), and IFNgamma-inducible protein-10 (IP-10) chemokines by human neutrophils. J Immunol 1999;162:4928-37.
-
(1999)
J Immunol
, vol.162
, pp. 4928-4937
-
-
Gasperini, S.1
Marchi, M.2
Calzetti, F.3
Laudanna, C.4
Vicentini, L.5
Olsen, H.6
-
38
-
-
0037307930
-
Blockade of programmed death-1 ligands on dendritic cells enhances T cell activation and cytokine production
-
Brown JA, Dorfman DM, Ma FR, Sullivan EL, Munoz O, Wood CR, et al. Blockade of programmed death-1 ligands on dendritic cells enhances T cell activation and cytokine production. J Immunol 2003; 170:1257-66.
-
(2003)
J Immunol
, vol.170
, pp. 1257-1266
-
-
Brown, J.A.1
Dorfman, D.M.2
Ma, F.R.3
Sullivan, E.L.4
Munoz, O.5
Wood, C.R.6
-
39
-
-
0242559053
-
Endothelial expression of PD-L1 and PD-L2 down-regulates CD8+T cell activation and cytolysis
-
Rodig N, Ryan T, Allen JA, Pang H, Grabie N, Chernova T, et al. Endothelial expression of PD-L1 and PD-L2 down-regulates CD8+T cell activation and cytolysis. Eur J Immunol 2003;33:3117-26.
-
(2003)
Eur J Immunol
, vol.33
, pp. 3117-3126
-
-
Rodig, N.1
Ryan, T.2
Allen, J.A.3
Pang, H.4
Grabie, N.5
Chernova, T.6
-
40
-
-
84867544962
-
PD-1 blockade enhances T-cell migration to tumors by elevating IFN-gamma inducible chemokines
-
Peng W, Liu C, Xu C, Lou Y, Chen J, Yang Y, et al. PD-1 blockade enhances T-cell migration to tumors by elevating IFN-gamma inducible chemokines. Cancer Res 2012;72:5209-18.
-
(2012)
Cancer Res
, vol.72
, pp. 5209-5218
-
-
Peng, W.1
Liu, C.2
Xu, C.3
Lou, Y.4
Chen, J.5
Yang, Y.6
-
41
-
-
84921456279
-
Combination therapy with anti-CTLA-4 and anti-PD-1 leads to distinct immunologic changes in vivo
-
Das R, Verma R, Sznol M, Boddupalli CS, Gettinger SN, Kluger H, et al. Combination therapy with anti-CTLA-4 and anti-PD-1 leads to distinct immunologic changes in vivo. J Immunol 2015;194:950-9.
-
(2015)
J Immunol
, vol.194
, pp. 950-959
-
-
Das, R.1
Verma, R.2
Sznol, M.3
Boddupalli, C.S.4
Gettinger, S.N.5
Kluger, H.6
|