Peptide amphiphile nanofiber hydrogel delivery of sonic hedgehog protein to the cavernous nerve to promote regeneration and prevent erectile dysfunction

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 13, Issue 1, 2017, Pages 95-101

  Choe, Shawn ^a   Bond, Christopher W ^b   Harrington, Daniel A ^c   Stupp, Samuel I ^d   McVary, Kevin T ^e   Podlasek, Carol A ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c RICE UNIVERSITY   (United States)

^d Northwestern University   (United States)

^e SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cavernous nerve injury (prostatectomy); Erectile dysfunction; Peptide amphiphile nanofiber hydrogel; Regeneration; Sonic hedgehog

Indexed keywords

AMPHIPHILES; CELL DEATH; CELL MEMBRANES; HYDROGELS; NANOFIBERS; PEPTIDES; PROTEINS; UROLOGY;

ERECTILE DYSFUNCTION; NERVE INJURIES; PEPTIDE AMPHIPHILES; REGENERATION; SONIC HEDGEHOGS;

NEURONS;

AMPHOPHILE; NANOFIBER; PEPTIDE; PROTEIN PATCHED 1; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; HYDROGEL; SMO PROTEIN, RAT;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CAVERNOUS NERVE; CELL SURFACE; CONTROLLED STUDY; CRUSH TRAUMA; DRUG DELIVERY SYSTEM; ERECTILE DYSFUNCTION; GLIA; HYDROGEL; NERVE; NERVE CELL; NERVE REGENERATION; NEUROPROTECTION; NONHUMAN; PROTEIN LOCALIZATION; RAT; ANIMAL; CHEMISTRY; DRUG EFFECTS; INNERVATION; MALE; METABOLISM; NERVE CRUSH; PENIS; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ANIMALS; ERECTILE DYSFUNCTION; HEDGEHOG PROTEINS; HYDROGELS; MALE; NANOFIBERS; NERVE CRUSH; NERVE REGENERATION; PENIS; PEPTIDES; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SMOOTHENED RECEPTOR;

EID: 84995872936     PISSN: 15499634     EISSN: 15499642     Source Type: Journal    
DOI: 10.1016/j.nano.2016.08.032     Document Type: Article

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