-
1
-
-
84891790401
-
The NHGRI GWAS catalog, a curated resource of SNP-trait associations
-
Welter, D. et al. The NHGRI GWAS catalog, a curated resource of SNP-trait associations. Nucleic Acids Res. 42, D1001-D1006 (2014).
-
(2014)
Nucleic Acids Res.
, vol.42
, pp. D1001-D1006
-
-
Welter, D.1
-
2
-
-
42349112088
-
Genome-wide association studies for complex traits: Consensus, uncertainty and challenges
-
McCarthy, M. I. et al. Genome-wide association studies for complex traits: consensus, uncertainty and challenges. Nat. Rev. Genet. 9, 356-369 (2008).
-
(2008)
Nat. Rev. Genet.
, vol.9
, pp. 356-369
-
-
McCarthy, M.I.1
-
3
-
-
33646443682
-
Genome-wide association mapping in Arabidopsis identifies previously known flowering time and pathogen resistance genes
-
Aranzana, M. J. et al. Genome-wide association mapping in Arabidopsis identifies previously known flowering time and pathogen resistance genes. PLOS Genet. 1, e60 (2005).
-
(2005)
PLOS Genet.
, vol.1
, pp. e60
-
-
Aranzana, M.J.1
-
4
-
-
84871345504
-
The nature of confounding in genome-wide association studies
-
Vilhjalmsson, B. J., Nordborg, M. The nature of confounding in genome-wide association studies. Nat. Rev. Genet. 14, 1-2 (2013).
-
(2013)
Nat. Rev. Genet.
, vol.14
, pp. 1-2
-
-
Vilhjalmsson, B.J.1
Nordborg, M.2
-
5
-
-
31744440502
-
A unified mixed-model method for association mapping that accounts for multiple levels of relatedness
-
Yu, J. et al. A unified mixed-model method for association mapping that accounts for multiple levels of relatedness. Nat. Genet. 38, 203-208 (2006).
-
(2006)
Nat. Genet.
, vol.38
, pp. 203-208
-
-
Yu, J.1
-
6
-
-
45149105926
-
Efficient control of population structure in model organism association mapping
-
Kang, H. M. et al. Efficient control of population structure in model organism association mapping. Genetics 178, 1709-1723 (2008).
-
(2008)
Genetics
, vol.178
, pp. 1709-1723
-
-
Kang, H.M.1
-
7
-
-
77950301214
-
Variance component model to account for sample structure in genome-wide association studies
-
Kang, H. M. et al. Variance component model to account for sample structure in genome-wide association studies. Nat. Genet. 42, 348-354 (2010).
-
(2010)
Nat. Genet.
, vol.42
, pp. 348-354
-
-
Kang, H.M.1
-
8
-
-
77950299137
-
Mixed linear model approach adapted for genome-wide association studies
-
Zhang, Z. et al. Mixed linear model approach adapted for genome-wide association studies. Nat. Genet. 42, 355-360 (2010).
-
(2010)
Nat. Genet.
, vol.42
, pp. 355-360
-
-
Zhang, Z.1
-
9
-
-
80053372166
-
FaST linear mixed models for genome-wide association studies
-
Lippert, C. et al. FaST linear mixed models for genome-wide association studies. Nat. Methods 8, 833-835 (2011).
-
(2011)
Nat. Methods
, vol.8
, pp. 833-835
-
-
Lippert, C.1
-
10
-
-
84866946205
-
Rapid variance components-based method for whole-genome association analysis
-
Svishcheva, G. R., Axenovich, T. I., Belonogova, N. M., van Duijn, C. M., Aulchenko, Y. S. Rapid variance components-based method for whole-genome association analysis. Nat. Genet. 44, 1166-1170 (2012).
-
(2012)
Nat. Genet.
, vol.44
, pp. 1166-1170
-
-
Svishcheva, G.R.1
Axenovich, T.I.2
Belonogova, N.M.3
Van Duijn, C.M.4
Aulchenko, Y.S.5
-
11
-
-
84863003734
-
Genome-wide efficient mixed-model analysis for association studies
-
Zhou, X., Stephens, M. Genome-wide efficient mixed-model analysis for association studies. Nat. Genet. 44, 821-824 (2012).
-
(2012)
Nat. Genet.
, vol.44
, pp. 821-824
-
-
Zhou, X.1
Stephens, M.2
-
12
-
-
55849133422
-
Efficient methods to compute genomic predictions
-
VanRaden, P. M. Efficient methods to compute genomic predictions. J. Dairy Sci. 91, 4414-4423 (2008).
-
(2008)
J. Dairy Sci.
, vol.91
, pp. 4414-4423
-
-
VanRaden, P.M.1
-
13
-
-
84861988364
-
Improved linear mixed models for genome-wide association studies
-
Listgarten, J. et al. Improved linear mixed models for genome-wide association studies. Nat. Methods 9, 525-526 (2012).
-
(2012)
Nat. Methods
, vol.9
, pp. 525-526
-
-
Listgarten, J.1
-
14
-
-
84895801913
-
Advantages and pitfalls in the application of mixed-model association methods
-
Yang, J., Zaitlen, N. A., Goddard, M. E., Visscher, P. M., Price, A. L. Advantages and pitfalls in the application of mixed-model association methods. Nat. Genet. 46, 100-106 (2014).
-
(2014)
Nat. Genet.
, vol.46
, pp. 100-106
-
-
Yang, J.1
Zaitlen, N.A.2
Goddard, M.E.3
Visscher, P.M.4
Price, A.L.5
-
15
-
-
84862991434
-
An efficient multi-locus mixed-model approach for genomewide association studies in structured populations
-
Segura, V. et al. An efficient multi-locus mixed-model approach for genomewide association studies in structured populations. Nat. Genet. 44, 825-830 (2012).
-
(2012)
Nat. Genet.
, vol.44
, pp. 825-830
-
-
Segura, V.1
-
16
-
-
84872542418
-
A Lasso multi-marker mixed model for association mapping with population structure correction
-
Rakitsch, B., Lippert, C., Stegle, O., Borgwardt, K. A Lasso multi-marker mixed model for association mapping with population structure correction. Bioinformatics 29, 206-214 (2013).
-
(2013)
Bioinformatics
, vol.29
, pp. 206-214
-
-
Rakitsch, B.1
Lippert, C.2
Stegle, O.3
Borgwardt, K.4
-
17
-
-
84874783818
-
Polygenic modeling with Bayesian sparse linear mixed models
-
Zhou, X., Carbonetto, P., Stephens, M. Polygenic modeling with Bayesian sparse linear mixed models. PLoS Genet. 9, e1003264 (2013).
-
(2013)
PLoS Genet.
, vol.9
, pp. e1003264
-
-
Zhou, X.1
Carbonetto, P.2
Stephens, M.3
-
18
-
-
84924060689
-
Efficient Bayesian mixed-model analysis increases association power in large cohorts
-
Loh, P.-R. et al. Efficient Bayesian mixed-model analysis increases association power in large cohorts. Nat. Genet. 47, 284-290 (2015).
-
(2015)
Nat. Genet.
, vol.47
, pp. 284-290
-
-
Loh, P.-R.1
-
19
-
-
68249130288
-
Mapping in structured populations by resample model averaging
-
Valdar, W., Holmes, C. C., Mott, R., Flint, J. Mapping in structured populations by resample model averaging. Genetics 182, 1263-1277 (2009).
-
(2009)
Genetics
, vol.182
, pp. 1263-1277
-
-
Valdar, W.1
Holmes, C.C.2
Mott, R.3
Flint, J.4
-
20
-
-
84929130444
-
Testing for genetic associations in arbitrarily structured populations
-
Song, M., Hao, W., Storey, J. D. Testing for genetic associations in arbitrarily structured populations. Nat. Genet. 47, 550-554 (2015).
-
(2015)
Nat. Genet.
, vol.47
, pp. 550-554
-
-
Song, M.1
Hao, W.2
Storey, J.D.3
-
21
-
-
0027946344
-
Controlling the type i and type II errors in mapping quantitative trait loci
-
Jansen, R. C. Controlling the type I and type II errors in mapping quantitative trait loci. Genetics 138, 871-881 (1994).
-
(1994)
Genetics
, vol.138
, pp. 871-881
-
-
Jansen, R.C.1
-
22
-
-
44849141742
-
Hierarchical testing of variable importance
-
Meinshausen, N. Hierarchical testing of variable importance. Biometrika 95, 265-278 (2008).
-
(2008)
Biometrika
, vol.95
, pp. 265-278
-
-
Meinshausen, N.1
-
23
-
-
84969799996
-
Hierarchical testing in the high-dimensional setting with correlated variables
-
Mandozzi, J., Buhlmann, P. Hierarchical testing in the high-dimensional setting with correlated variables. J. Am. Stat. Assoc. 111, 331-343 (2016).
-
(2016)
J. Am. Stat. Assoc.
, vol.111
, pp. 331-343
-
-
Mandozzi, J.1
Buhlmann, P.2
-
24
-
-
85007210894
-
Assessing statistical significance in multivariable genome wide association analysis
-
Buzdugan, L. et al. Assessing statistical significance in multivariable genome wide association analysis. Bioinformatics 32, 1990-2000 (2016).
-
(2016)
Bioinformatics
, vol.32
, pp. 1990-2000
-
-
Buzdugan, L.1
-
25
-
-
85194972808
-
Regression shrinkage and selection via the LASSO
-
Tibshirani, R. J. Regression shrinkage and selection via the LASSO. J. R. Stat. Soc. Ser. B Methodol. 58, 267-288 (1996).
-
(1996)
J. R. Stat. Soc. Ser. B Methodol.
, vol.58
, pp. 267-288
-
-
Tibshirani, R.J.1
-
26
-
-
84856270364
-
Genome-wide patterns of genetic variation in worldwide Arabidopsis thaliana accessions from the RegMap panel
-
Horton, M. W. et al. Genome-wide patterns of genetic variation in worldwide Arabidopsis thaliana accessions from the RegMap panel. Nat. Genet. 44, 212-216 (2012).
-
(2012)
Nat. Genet.
, vol.44
, pp. 212-216
-
-
Horton, M.W.1
-
27
-
-
84994852722
-
Controlling the false discovery rate: A practical and powerful approach to multiple testing
-
Benjamini, Y., Hochberg, Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J. R. Stat. Soc. 57, 289-300 (1995).
-
(1995)
J. R. Stat. Soc.
, vol.57
, pp. 289-300
-
-
Benjamini, Y.1
Hochberg, Y.2
-
28
-
-
0000380147
-
Estimating the locations and the sizes of the effects of quantitative trait loci using flanking markers
-
Martnez, O., Curnow, R. N. Estimating the locations and the sizes of the effects of quantitative trait loci using flanking markers. Theor. Appl. Genet. 85, 480-488 (1992).
-
(1992)
Theor. Appl. Genet.
, vol.85
, pp. 480-488
-
-
Martnez, O.1
Curnow, R.N.2
-
29
-
-
84891372805
-
Genome-wide association study using cellular traits identifies a new regulator of root development in Arabidopsis
-
Meijon, M., Satbhai, S. B., Tsuchimatsu, T., Busch, W. Genome-wide association study using cellular traits identifies a new regulator of root development in Arabidopsis. Nat. Genet. 46, 77-81 (2014).
-
(2014)
Nat. Genet.
, vol.46
, pp. 77-81
-
-
Meijon, M.1
Satbhai, S.B.2
Tsuchimatsu, T.3
Busch, W.4
-
30
-
-
77950343795
-
Pepr2 is a second receptor for the Pep1 and Pep2 peptides and contributes to defense responses in Arabidopsis
-
Yamaguchi, Y., Huffaker, A., Bryan, A. C., Tax, F. E., Ryan, C. A. Pepr2 is a second receptor for the Pep1 and Pep2 peptides and contributes to defense responses in Arabidopsis. Plant Cell 22, 508-522 (2010).
-
(2010)
Plant Cell
, vol.22
, pp. 508-522
-
-
Yamaguchi, Y.1
Huffaker, A.2
Bryan, A.C.3
Tax, F.E.4
Ryan, C.A.5
-
31
-
-
75649122259
-
A high-resolution association mapping panel for the dissection of complex traits in mice
-
Bennett, B. J. et al. A high-resolution association mapping panel for the dissection of complex traits in mice. Genome Res. 20, 281-290 (2010).
-
(2010)
Genome Res.
, vol.20
, pp. 281-290
-
-
Bennett, B.J.1
-
32
-
-
80051684615
-
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
-
Sawcer, S. et al. Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature 476, 214-219 (2011).
-
(2011)
Nature
, vol.476
, pp. 214-219
-
-
Sawcer, S.1
-
33
-
-
67651108806
-
The genetics of quantitative traits: Challenges and prospects
-
Mackay, T. F. C., Stone, E. A., Ayroles, J. F. The genetics of quantitative traits: challenges and prospects. Nat. Rev. Genet. 10, 565-577 (2009).
-
(2009)
Nat. Rev. Genet.
, vol.10
, pp. 565-577
-
-
MacKay, T.F.C.1
Stone, E.A.2
Ayroles, J.F.3
-
34
-
-
80053384429
-
Whole-genome sequencing of multiple Arabidopsis thaliana populations
-
Cao, J. et al. Whole-genome sequencing of multiple Arabidopsis thaliana populations. Nat. Genet. 43, 956-963 (2011).
-
(2011)
Nat. Genet.
, vol.43
, pp. 956-963
-
-
Cao, J.1
-
35
-
-
0034957069
-
The distribution of the effects of genes affecting quantitative traits in livestock
-
Hayes, B., Goddard, M. E. The distribution of the effects of genes affecting quantitative traits in livestock. Genet. Sel. Evol. 33, 209 (2001).
-
(2001)
Genet. Sel. Evol.
, vol.33
, pp. 209
-
-
Hayes, B.1
Goddard, M.E.2
-
36
-
-
84858865636
-
The recombination landscape in Arabidopsis thaliana F2 populations
-
Salome, P. A. et al. The recombination landscape in Arabidopsis thaliana F2 populations. Heredity 108, 447-455 (2012).
-
(2012)
Heredity
, vol.108
, pp. 447-455
-
-
Salome, P.A.1
-
37
-
-
85136354327
-
Ridge regression and other kernels for genomic selection with R package rrBLUP
-
Endelman, J. B. Ridge regression and other kernels for genomic selection with R package rrBLUP. Plant Genome J. 4, 250 (2011).
-
(2011)
Plant Genome J.
, vol.4
, pp. 250
-
-
Endelman, J.B.1
-
38
-
-
78449299668
-
R/qtl: High-throughput multiple QTL mapping
-
Arends, D., Prins, P., Jansen, R. C., Broman, K. W. R/qtl: high-throughput multiple QTL mapping. Bioinformatics 26, 2990-2992 (2010).
-
(2010)
Bioinformatics
, vol.26
, pp. 2990-2992
-
-
Arends, D.1
Prins, P.2
Jansen, R.C.3
Broman, K.W.4
-
39
-
-
84867853254
-
Natural Arabidopsis brx loss-offunction alleles confer root adaptation to acidic soil
-
Gujas, B., Alonso-Blanco, C., Hardtke, C. S. Natural Arabidopsis brx loss-offunction alleles confer root adaptation to acidic soil. Curr. Biol. 22, 1962-1968 (2012).
-
(2012)
Curr. Biol.
, vol.22
, pp. 1962-1968
-
-
Gujas, B.1
Alonso-Blanco, C.2
Hardtke, C.S.3
|