Combinations and loads of bacteria affect the cytokine production by fetal membranes: An in vitro study

American Journal of Reproductive Immunology

Volumn 76, Issue 6, 2016, Pages 504-511

  Noda Nicolau, Nathalia Mayumi ^a,b   Polettini, Jossimara ^a,b   Peltier, Morgan R ^c   da Silva, Márcia Guimarães ^b   Menon, Ramkumar ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

^b SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^c WINTHROP UNIVERSITY HOSPITAL   (United States)

Author keywords

Gardnerella vaginalis; genital mycoplasmas; polybacterial infection

Indexed keywords

CASPASE RECRUITMENT DOMAIN PROTEIN 15; CASPASE RECRUITMENT DOMAIN PROTEIN 4; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1 RECEPTOR TYPE I; INTERLEUKIN 1 RECEPTOR TYPE II; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 8; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 1; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; CYTOKINE; IL10 PROTEIN, HUMAN;

ARTICLE; BACTERIAL LOAD; BACTERIUM COLONY; COLONY FORMING UNIT; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; FETUS; FETUS MEMBRANE; GARDNERELLA VAGINALIS; HUMAN; HUMAN TISSUE; IMMUNE RESPONSE; IN VITRO STUDY; INNATE IMMUNITY; MYCOPLASMA; MYCOPLASMA HOMINIS; NONHUMAN; PRIORITY JOURNAL; UREAPLASMA UREALYTICUM; COCULTURE; EMBRYO MEMBRANE; FEMALE; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HEAT; HOST PATHOGEN INTERACTION; IMMUNOLOGY; MICROBIOLOGY; PREGNANCY; REPEAT CESAREAN SECTION; TISSUE CULTURE TECHNIQUE;

CESAREAN SECTION, REPEAT; COCULTURE TECHNIQUES; CYTOKINES; EXTRAEMBRYONIC MEMBRANES; FEMALE; GARDNERELLA VAGINALIS; GENE EXPRESSION REGULATION; HOST-PATHOGEN INTERACTIONS; HOT TEMPERATURE; HUMANS; INTERLEUKIN-10; INTERLEUKIN-13; INTERLEUKIN-8; MYCOPLASMA HOMINIS; PREGNANCY; TISSUE CULTURE TECHNIQUES; UREAPLASMA UREALYTICUM;

EID: 84994823935     PISSN: 10467408     EISSN: 16000897     Source Type: Journal    
DOI: 10.1111/aji.12596     Document Type: Article

References (36)

1. Slattery MM, Geary M, Morrison JJ. Obstetric antecedents for preterm delivery. J Perinat Med. 2008;36:306–309.
2. Lo C, Hsu J, Hsieh C, Hsieh T, Hung T. Risk factors for spontaneous preterm delivery before 34 weeks of gestation among taiwanese women. Taiwan J Obstet Gynecol. 2007;46:389–394.
3. Donders GG, Van Calsteren K, Bellen G, et al. Predictive value for preterm birth of abnormal vaginal flora, bacterial vaginosis and aerobic vaginitis during the first trimester of pregnancy. BJOG. 2009;116:1315–1324.
4. Leitich H, Bodner-Adler B, Brunbauer M, Kaider A, Egarter C, Husslein P. Bacterial vaginosis as a risk factor for preterm delivery: a meta-analysis. Am J Obstet Gynecol. 2003;189:139–147.
5. Menon R. Oxidative stress damage as a detrimental factor in preterm birth pathology. Front Immunol. 2014;5:1–14.
6. Romero R, Espinoza J, Gonçalves LF, Kusanovic JP, Friel LA, Nien JK. Inflammation in preterm and term labour and delivery. Semin Fetal Neonatal Med 2006;11:317–326.
7. DiGiulio DB. Diversity of microbes in amniotic fluid. Semin Fetal Neonatal Med. 2012;17:2–11.
8. Capoccia R, Greub G, Baud D. Ureaplasma urealyticum, Mycoplasma hominis and adverse pregnancy outcomes. Curr Opin Infect Dis. 2013;26:231–240.
9. Abele-Horn M, Scholz M, Wolff C, Kolben M. High-density vaginal Ureaplasma urealyticum colonization as a risk factor for chorioamnionitis and preterm delivery. Acta Obstet Gynecol Scand. 2000;79:973–978.
10. Kacerovský M, Pavlovský M, Tosner J. Preterm premature rupture of the membranes and genital mycoplasmas. Acta Medica (Hradec Kralove). 2009;52:117–120.
11. Gerber S, Vial Y, Hohlfeld P, Witkin SS. Detection of Ureaplasma urealyticum in second-trimester amniotic fluid by polymerase chain reaction correlates with subsequent preterm labor and delivery. J Infect Dis. 2003;187:518–521.
12. Witt A, Berger A, Gruber CJ, et al. Increased intrauterine frequency of Ureaplasma urealyticum in women with preterm labor and preterm premature rupture of the membranes and subsequent cesarean delivery. Am J Obstet Gynecol. 2005;193:1663–1669.
13. Aaltone R, Jalava J, Laurikaine E, Kärkkäinen U, Alanen A. Cervical ureaplasma urealyticum colonization: comparison of PCR and culture for its detection and association with preterm birth. Scand J Infect Dis. 2002;34:35–40.
14. Harada K, Tanaka H, Komori S, et al. Vaginal infection with Ureaplasma urealyticum accounts for preterm delivery via induction of inflammatory responses. Microbiol Immunol. 2008;52:297–304.
15. Nguyen DP, Gerber S, Hohlfeld P, Sandrine G, Witkin SS. Mycoplasma hominis in mid-trimester amniotic fluid: relation to pregnancy outcome. J Perinat Med. 2005;32:323–326.
16. Larsen B, Hwang J. Mycoplasma, Ureaplasma, and adverse pregnancy outcomes: a fresh look. Infect Dis Obstet Gynecol. 2010;2010. pii: 521921.
17. Kwak D-W, Hwang H-S, Kwon J-Y, Park Y-W, Kim Y-H. Co-infection with vaginal Ureaplasma urealyticum and Mycoplasma hominis increases adverse pregnancy outcomes in patients with preterm labor or preterm premature rupture of membranes. J Matern Fetal Neonatal Med. 2013;7058:1–5.
18. Lamont RF, Taylor-Robinson D, Wigglesworth JS, Furr PM, Evans RT, Elder MG. The role of mycoplasmas, ureaplasmas and chlamydiae in the genital tract of women presenting in spontaneous early preterm labour. J Med Microbiol. 1987;24:253–257.
19. Romero R, Miranda J, Chaiworapongsa T, et al. A novel molecular microbiologic technique for the rapid diagnosis of microbial invasion of the amniotic cavity and intra-amniotic infection in preterm labor with intact membranes. Am J Reprod Immunol. 2014;71:330–358.
20. Zaga-Clavellina V, Martha RVM, Flores-Espinosa P. In vitro secretion profile of pro-inflammatory cytokines IL-1β, TNF-α, IL-6, and of Human Beta-Defensins (HBD)-1, HBD-2, and HBD-3 from human chorioamniotic membranes after selective stimulation with gardnerella vaginalis. Am J Reprod Immunol 2012;67(Il):34–43.
21. Menon R, Peltier MR, Eckardt J, Fortunato SJ. Diversity in cytokine response to bacteria associated with preterm birth by fetal membranes. Am J Obstet Gynecol 2009;201:306. e1–306.e6.
22. Hsu C, Meaddough E, Aversa K, et al. Dual roles of amniotic fluid nitric oxide and prostaglandin E2 in preterm labor with intra-amniotic infection. Am J Perinatol. 1998;15:683–687.
23. Sibley CD, Duan K, Fischer C, et al. Discerning the complexity of community interactions using a Drosophila model of polymicrobial infections. PLoS Pathog 2008;4:e1000184.
24. Hillier SL. Diagnostic microbiology of bacterial vaginosis. Am J Obstet Gynecol. 1993;169:455–459.
25. DiGiulio DB, Romero R, Amogan HP, et al. Microbial prevalence, diversity and abundance in amniotic fluid during preterm labor: a molecular and culture-based investigation. PLoS One. 2008;3:1–10.
26. Patterson JL, Stull-Lane A, Girerd PH, Jefferson KK. Analysis of adherence, biofilm formation and cytotoxicity suggests a greater virulence potential of Gardnerella vaginalis relative to other bacterial-vaginosis-associated anaerobes. Microbiology. 2010;156:392–399.
27. Menon R, Swan KF, Lyden TW, Rote NS, Fortunato SJ. Expression of inflammatory cytokines (interleukin-1 beta and interleukin-6) in amniochorionic membranes. Am J Obstet Gynecol. 1995;172:493–500.
28. Marconi C, De Andrade Ramos BR, Peraçoli JC, Donders GGG, Da Silva MG. Amniotic fluid Interleukin-1 Beta and Interleukin-6, but not Interleukin-8 correlate with microbial invasion of the amniotic cavity in preterm labor. Am J Reprod Immunol 2011;65:549–556.
29. Kim YM, Romero R, Chaiworapongsa T, et al. Toll-like receptor-2 and -4 in the chorioamniotic membranes in spontaneous labor at term and in preterm parturition that are associated with chorioamnionitis. Am J Obstet Gynecol. 2004;191:1346–1355.
30. Zaga-Clavellina V, Garcia-Lopez G, Flores-Herrera H, et al. In vitro secretion profiles of interleukin (IL)-1beta, IL-6, IL-8, IL-10, and TNF alpha after selective infection with Escherichia coli in human fetal membranes. Reprod Biol Endocrinol. 2007;5:46.
31. Basraon SK, Costantine MM, Saade G, Menon R. The effect of simvastatin on infection-induced inflammatory response of human fetal membranes. Am J Reprod Immunol. 2015;74:54–61.
32. Funderburg N, Lederman MM, Feng Z, Drage MG, Jadlowsky J, Harding CV, et al. Human -defensin-3 activates professional antigen-presenting cells via Toll-like receptors 1 and 2. Proc Natl Acad Sci U S A. 2007;104:18631–18635.
33. Bredeson S, Papaconstantinou J, Deford JH, Kechichian T. HMGB1 promotes a p38MAPK associated non-infectious inflammatory response pathway in human fetal membranes. PLoS One. 2014;9:1–18.
34. Park JS, Gamboni-robertson F, He Q, et al. High mobility group box 1 protein interacts with multiple Toll-like receptors. Am J Physiol Cell Physiol. 2006;290:917–924.
35. Romero-Rojas A, Ponce-Hernández C, Mendoza S, Reyes-Esparza J, Estrada-Parra S, Hadden J. Immunomodulatory properties of Mycoplasma pulmonis. II. Studies on the mechanisms of immunomodulation. Int Immunopharmacol. 2001;1:1689–1697.
36. Reisenberger K, Egarter C, Schiebel I, Obermair A, Kiss H, Lehner R. In vitro cytokine and prostaglandin production by amnion cells in the presence of bacteria. Am J Obstet Gynecol. 1997;176:981–984.