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Volumn 2015, Issue 1, 2015, Pages 8-13

Iron deficiency: New insights into diagnosis and treatment

Author keywords

[No Author keywords available]

Indexed keywords

IRON; FERRITIN; TRANSFERRIN;

EID: 84994823416     PISSN: 15204391     EISSN: 15204383     Source Type: Journal    
DOI: 10.1182/asheducation-2015.1.8     Document Type: Article
Times cited : (125)

References (41)
  • 1
    • 84894067309 scopus 로고    scopus 로고
    • A systematic analysis of global anemia burden from 1990 to 2010
    • Kassebaum NJ, Jasrasaria R, Naghavi M, et al. A systematic analysis of global anemia burden from 1990 to 2010. Blood. 2014;123(5):615-624.
    • (2014) Blood , vol.123 , Issue.5 , pp. 615-624
    • Kassebaum, N.J.1    Jasrasaria, R.2    Naghavi, M.3
  • 2
    • 77954249308 scopus 로고    scopus 로고
    • Two to tango: Regulation of Mammalian iron metabolism
    • Hentze MW, Muckenthaler MU, Galy B, Camaschella C. Two to tango: regulation of Mammalian iron metabolism. Cell. 2010;142(1):24-38.
    • (2010) Cell , vol.142 , Issue.1 , pp. 24-38
    • Hentze, M.W.1    Muckenthaler, M.U.2    Galy, B.3    Camaschella, C.4
  • 3
    • 79952483290 scopus 로고    scopus 로고
    • Iron deficiency in blood donors: Analysis of enrollment data from the REDS-II Donor Iron Status Evaluation (RISE) study
    • Cable RG, Glynn SA, Kiss JE, et al. Iron deficiency in blood donors: analysis of enrollment data from the REDS-II Donor Iron Status Evaluation (RISE) study. Transfusion. 2011;51(3):511-522.
    • (2011) Transfusion , vol.51 , Issue.3 , pp. 511-522
    • Cable, R.G.1    Glynn, S.A.2    Kiss, J.E.3
  • 5
    • 80052587883 scopus 로고    scopus 로고
    • Association of HFE and TMPRSS6 genetic variants with iron and erythrocyte parameters is only in part dependent on serum hepcidin concentrations
    • Traglia M, Girelli D, Biino G, et al. Association of HFE and TMPRSS6 genetic variants with iron and erythrocyte parameters is only in part dependent on serum hepcidin concentrations. J Med Genet. 2011;48(9): 629-634.
    • (2011) J Med Genet , vol.48 , Issue.9 , pp. 629-634
    • Traglia, M.1    Girelli, D.2    Biino, G.3
  • 6
    • 79959517566 scopus 로고    scopus 로고
    • Serum hepcidin: Reference ranges and biochemical correlates in the general population
    • Galesloot TE, Vermeulen SH, Geurts-Moespot AJ, et al. Serum hepcidin: reference ranges and biochemical correlates in the general population. Blood. 2011;117(25):e218-e225.
    • (2011) Blood , vol.117 , Issue.25 , pp. e218-e225
    • Galesloot, T.E.1    Vermeulen, S.H.2    Geurts-Moespot, A.J.3
  • 7
    • 84873361483 scopus 로고    scopus 로고
    • The IRP1-HIF-2alpha axis coordinates iron and oxygen sensing with erythropoiesis and iron absorption
    • Anderson SA, Nizzi CP, Chang YI, et al. The IRP1-HIF-2alpha axis coordinates iron and oxygen sensing with erythropoiesis and iron absorption. Cell Metab. 2013;17(2):282-290.
    • (2013) Cell Metab , vol.17 , Issue.2 , pp. 282-290
    • Anderson, S.A.1    Nizzi, C.P.2    Chang, Y.I.3
  • 8
    • 84873338684 scopus 로고    scopus 로고
    • Deletion of iron regulatory protein 1 causes polycythemia and pulmonary hypertension in mice through translational derepression of HIF2alpha
    • Ghosh MC, Zhang DL, Jeong SY, et al. Deletion of iron regulatory protein 1 causes polycythemia and pulmonary hypertension in mice through translational derepression of HIF2alpha. Cell Metab. 2013;17(2): 271-281.
    • (2013) Cell Metab , vol.17 , Issue.2 , pp. 271-281
    • Ghosh, M.C.1    Zhang, D.L.2    Jeong, S.Y.3
  • 9
    • 84923293373 scopus 로고    scopus 로고
    • The second transferrin receptor regulates red blood cell production in mice
    • Nai A, Lidonnici MR, Rausa M, et al. The second transferrin receptor regulates red blood cell production in mice. Blood. 2015;125(7):1170-1179.
    • (2015) Blood , vol.125 , Issue.7 , pp. 1170-1179
    • Nai, A.1    Lidonnici, M.R.2    Rausa, M.3
  • 10
    • 84903578007 scopus 로고    scopus 로고
    • Identification of erythroferrone as an erythroid regulator of iron metabolism
    • Kautz L, Jung G, Valore EV, Rivella S, Nemeth E, Ganz T. Identification of erythroferrone as an erythroid regulator of iron metabolism. Nat Genet. 2014;46(7):678-684.
    • (2014) Nat Genet , vol.46 , Issue.7 , pp. 678-684
    • Kautz, L.1    Jung, G.2    Valore, E.V.3    Rivella, S.4    Nemeth, E.5    Ganz, T.6
  • 11
    • 56449096622 scopus 로고    scopus 로고
    • The serine protease matriptase-2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin
    • Silvestri L, Pagani A, Nai A, De Domenico I, Kaplan J, Camaschella C. The serine protease matriptase-2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin. Cell Metabm. 2008;8(6):502-511.
    • (2008) Cell Metabm , vol.8 , Issue.6 , pp. 502-511
    • Silvestri, L.1    Pagani, A.2    Nai, A.3    De Domenico, I.4    Kaplan, J.5    Camaschella, C.6
  • 12
    • 84899746695 scopus 로고    scopus 로고
    • Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy
    • Mancias JD, Wang X, Gygi SP, Harper JW, Kimmelman AC. Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy. Nature. 2014;509(7498):105-109.
    • (2014) Nature , vol.509 , Issue.7498 , pp. 105-109
    • Mancias, J.D.1    Wang, X.2    Gygi, S.P.3    Harper, J.W.4    Kimmelman, A.C.5
  • 13
    • 84886902763 scopus 로고    scopus 로고
    • The gut in iron homeostasis: Role of HIF-2 under normal and pathological conditions
    • Mastrogiannaki M, Matak P, Peyssonnaux C. The gut in iron homeostasis: role of HIF-2 under normal and pathological conditions. Blood. 2013;122(6):885-892.
    • (2013) Blood , vol.122 , Issue.6 , pp. 885-892
    • Mastrogiannaki, M.1    Matak, P.2    Peyssonnaux, C.3
  • 14
    • 84928963582 scopus 로고    scopus 로고
    • Iron-deficiency anemia
    • Camaschella C. Iron-deficiency anemia. N Engl J Med. 2015;372(19): 1832-1843.
    • (2015) N Engl J Med , vol.372 , Issue.19 , pp. 1832-1843
    • Camaschella, C.1
  • 15
    • 84924990173 scopus 로고    scopus 로고
    • The prevalence of iron deficiency anaemia in patients undergoing bariatric surgery
    • Khanbhai M, Dubb S, Patel K, Ahmed A, Richards T. The prevalence of iron deficiency anaemia in patients undergoing bariatric surgery. Obes Res Clin Pract. 2015;9(1):45-49.
    • (2015) Obes Res Clin Pract , vol.9 , Issue.1 , pp. 45-49
    • Khanbhai, M.1    Dubb, S.2    Patel, K.3    Ahmed, A.4    Richards, T.5
  • 16
    • 84924431382 scopus 로고    scopus 로고
    • Trends and racial/ethnic disparities in gluten-sensitive problems in the United States: Findings from the National Health and Nutrition Examination Surveys from 1988 to 2012
    • Choung RS, Ditah IC, Nadeau AM, et al. Trends and racial/ethnic disparities in gluten-sensitive problems in the United States: findings from the National Health and Nutrition Examination Surveys from 1988 to 2012. Am J Gastroenterol. 2015;110(3):455-461.
    • (2015) Am J Gastroenterol , vol.110 , Issue.3 , pp. 455-461
    • Choung, R.S.1    Ditah, I.C.2    Nadeau, A.M.3
  • 17
    • 84893048572 scopus 로고    scopus 로고
    • How i treat unexplained refractory iron deficiency anemia
    • Hershko C, Camaschella C. How I treat unexplained refractory iron deficiency anemia. Blood. 2014;123(3):326-333.
    • (2014) Blood , vol.123 , Issue.3 , pp. 326-333
    • Hershko, C.1    Camaschella, C.2
  • 18
    • 84916928192 scopus 로고    scopus 로고
    • FIND-CKD: A randomized trial of intravenous ferric carboxymaltose versus oral iron in patients with chronic kidney disease and iron deficiency anaemia
    • Macdougall IC, Bock AH, Carrera F, et al. FIND-CKD: a randomized trial of intravenous ferric carboxymaltose versus oral iron in patients with chronic kidney disease and iron deficiency anaemia. Nephrol Dial Transplant. 2014;29(11):2075-2084.
    • (2014) Nephrol Dial Transplant , vol.29 , Issue.11 , pp. 2075-2084
    • Macdougall, I.C.1    Bock, A.H.2    Carrera, F.3
  • 19
    • 80052102921 scopus 로고    scopus 로고
    • Anemia and iron deficiency in heart failure: Mechanisms and therapeutic approaches
    • van Veldhuisen DJ, Anker SD, Ponikowski P, Macdougall IC. Anemia and iron deficiency in heart failure: mechanisms and therapeutic approaches. Nat Rev Cardiol. 2011;8(9):485-493.
    • (2011) Nat Rev Cardiol , vol.8 , Issue.9 , pp. 485-493
    • Van Veldhuisen, D.J.1    Anker, S.D.2    Ponikowski, P.3    Macdougall, I.C.4
  • 20
    • 42649118442 scopus 로고    scopus 로고
    • Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA)
    • Finberg KE, Heeney MM, Campagna DR, et al. Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA). Nat Genet. 2008;40(5):569-571.
    • (2008) Nat Genet , vol.40 , Issue.5 , pp. 569-571
    • Finberg, K.E.1    Heeney, M.M.2    Campagna, D.R.3
  • 21
    • 70350628958 scopus 로고    scopus 로고
    • Common variants in TMPRSS6 are associated with iron status and erythrocyte volume
    • Benyamin B, Ferreira MA, Willemsen G, et al. Common variants in TMPRSS6 are associated with iron status and erythrocyte volume. Nat Genet. 2009;41(11):1173-1175.
    • (2009) Nat Genet , vol.41 , Issue.11 , pp. 1173-1175
    • Benyamin, B.1    Ferreira, M.A.2    Willemsen, G.3
  • 22
    • 84923272209 scopus 로고    scopus 로고
    • Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis
    • Benyamin B, Esko T, Ried JS, et al. Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis. Nat Commun. 2014;5:4926.
    • (2014) Nat Commun , vol.5 , pp. 4926
    • Benyamin, B.1    Esko, T.2    Ried, J.S.3
  • 23
    • 84925955044 scopus 로고    scopus 로고
    • Inter-ethnic differences in genetic variants within the transmembrane protease, serine 6 (TMPRSS6) gene associated with iron status indicators: A systematic review with metaanalyses
    • Gichohi-Wainaina WN, Towers GW, Swinkels DW, Zimmermann MB, Feskens EJ, Melse-Boonstra A. Inter-ethnic differences in genetic variants within the transmembrane protease, serine 6 (TMPRSS6) gene associated with iron status indicators: a systematic review with metaanalyses. Genes Nutr. 2015;10(1):442.
    • (2015) Genes Nutr , vol.10 , Issue.1 , pp. 442
    • Gichohi-Wainaina, W.N.1    Towers, G.W.2    Swinkels, D.W.3    Zimmermann, M.B.4    Feskens, E.J.5    Melse-Boonstra, A.6
  • 24
    • 80054840413 scopus 로고    scopus 로고
    • TMPRSS6 rs855791 modulates hepcidin transcription in vitro and serum hepcidin levels in normal individuals
    • Nai A, Pagani A, Silvestri L, et al. TMPRSS6 rs855791 modulates hepcidin transcription in vitro and serum hepcidin levels in normal individuals. Blood. 2011;118(16):4459-4462.
    • (2011) Blood , vol.118 , Issue.16 , pp. 4459-4462
    • Nai, A.1    Pagani, A.2    Silvestri, L.3
  • 25
    • 84922380798 scopus 로고    scopus 로고
    • Laboratory and genetic assessment of iron deficiency in blood donors
    • Kiss JE. Laboratory and genetic assessment of iron deficiency in blood donors. Clin Lab Med. 2015;35(1):73-91.
    • (2015) Clin Lab Med , vol.35 , Issue.1 , pp. 73-91
    • Kiss, J.E.1
  • 26
    • 78649753411 scopus 로고    scopus 로고
    • Detection, evaluation, and management of iron-restricted erythropoiesis
    • Goodnough LT, Nemeth E, Ganz T. Detection, evaluation, and management of iron-restricted erythropoiesis. Blood. 2010;116(23):4754-4761.
    • (2010) Blood , vol.116 , Issue.23 , pp. 4754-4761
    • Goodnough, L.T.1    Nemeth, E.2    Ganz, T.3
  • 27
    • 84887024735 scopus 로고    scopus 로고
    • Involvement of proprotein convertase PCSK7 in the regulation of systemic iron homeostasis
    • Schwienbacher C, Serafin A, Zanon A, Pramstaller PP, Pichler I, Hicks AA. Involvement of proprotein convertase PCSK7 in the regulation of systemic iron homeostasis. Hepatology. 2013;58(5):1860-1861.
    • (2013) Hepatology , vol.58 , Issue.5 , pp. 1860-1861
    • Schwienbacher, C.1    Serafin, A.2    Zanon, A.3    Pramstaller, P.P.4    Pichler, I.5    Hicks, A.A.6
  • 28
    • 14744278436 scopus 로고    scopus 로고
    • Anemia of chronic disease
    • Weiss G, Goodnough LT. Anemia of chronic disease. N Engl J Med. 2005;352(10):1011-1023.
    • (2005) N Engl J Med , vol.352 , Issue.10 , pp. 1011-1023
    • Weiss, G.1    Goodnough, L.T.2
  • 29
    • 84907778662 scopus 로고    scopus 로고
    • Microcytic anemi
    • DeLoughery TG.Microcytic anemia. N Engl J Med. 2014;371(14):1324-1331
    • (2014) N Engl J Med , vol.371 , Issue.14 , pp. 1324-1331
    • DeLoughery, T.G.1
  • 30
    • 84878470675 scopus 로고    scopus 로고
    • Iron refractory iron deficiency anemia
    • De Falco L, Sanchez M, Silvestri L, et al. Iron refractory iron deficiency anemia. Haematologica. 2013;98(6):845-853.
    • (2013) Haematologica , vol.98 , Issue.6 , pp. 845-853
    • De Falco, L.1    Sanchez, M.2    Silvestri, L.3
  • 31
    • 84923699055 scopus 로고    scopus 로고
    • Ferrous sulfate supplementation causes significant gastrointestinal side-effects in adults: A systematic review and meta-analysis
    • Tolkien Z, Stecher L, Mander AP, Pereira Di, Powell JJ. Ferrous sulfate supplementation causes significant gastrointestinal side-effects in adults: a systematic review and meta-analysis. PloS One. 2015;10(2): e0117383.
    • (2015) PloS One , vol.10 , Issue.2 , pp. e0117383
    • Tolkien, Z.1    Stecher, L.2    Mander, A.P.3    Pereira, D.I.4    Powell, J.J.5
  • 32
    • 84901372196 scopus 로고    scopus 로고
    • Iron supplementation benefits physical performance in women of reproductive age: A systematic review and meta-analysis
    • Pasricha SR, Low M, Thompson J, Farrell A, De-Regil LM. Iron supplementation benefits physical performance in women of reproductive age: a systematic review and meta-analysis. J Nutr. 2014;144(6):906-914.
    • (2014) J Nutr , vol.144 , Issue.6 , pp. 906-914
    • Pasricha, S.R.1    Low, M.2    Thompson, J.3    Farrell, A.4    De-Regil, L.M.5
  • 33
    • 84887595383 scopus 로고    scopus 로고
    • Effect of daily iron supplementation on health in children aged 4-23 months: A systematic review and meta-analysis of randomised controlled trials
    • Pasricha SR, Hayes E, Kalumba K, Biggs BA. Effect of daily iron supplementation on health in children aged 4-23 months: a systematic review and meta-analysis of randomised controlled trials. Lancet Glob Health. 2013;1(2):e77-e86.
    • (2013) Lancet Glob Health , vol.1 , Issue.2 , pp. e77-e86
    • Pasricha, S.R.1    Hayes, E.2    Kalumba, K.3    Biggs, B.A.4
  • 34
    • 30444459334 scopus 로고    scopus 로고
    • Effects of routine prophylactic supplementation with iron and folic acid on admission to hospital and mortality in preschool children in a high malaria transmission setting: Community-based, randomised, placebo-controlled trial
    • Sazawal S, Black RE, Ramsan M, et al. Effects of routine prophylactic supplementation with iron and folic acid on admission to hospital and mortality in preschool children in a high malaria transmission setting: community-based, randomised, placebo-controlled trial. Lancet. 2006; 367(9505):133-143.
    • (2006) Lancet , vol.367 , Issue.9505 , pp. 133-143
    • Sazawal, S.1    Black, R.E.2    Ramsan, M.3
  • 35
    • 84922559695 scopus 로고    scopus 로고
    • Oral iron supplementation after blood donation: A randomized clinical trial
    • Kiss JE, Brambilla D, Glynn SA, et al. Oral iron supplementation after blood donation: a randomized clinical trial. JAMA. 2015;313(6):575-583.
    • (2015) JAMA , vol.313 , Issue.6 , pp. 575-583
    • Kiss, J.E.1    Brambilla, D.2    Glynn, S.A.3
  • 36
    • 84883779160 scopus 로고    scopus 로고
    • Safety and efficacy of intravenous iron therapy in reducing requirement for allogeneic blood transfusion: Systematic review and meta-analysis of randomised clinical trials
    • Litton E, Xiao J, Ho KM. Safety and efficacy of intravenous iron therapy in reducing requirement for allogeneic blood transfusion: systematic review and meta-analysis of randomised clinical trials. BMJ. 2013;347:f4822.
    • (2013) BMJ , vol.347 , pp. f4822
    • Litton, E.1    Xiao, J.2    Ho, K.M.3
  • 37
    • 79955045302 scopus 로고    scopus 로고
    • Clinical use of intravenous iron: Administration, efficacy, and safety
    • Auerbach M, Ballard H. Clinical use of intravenous iron: administration, efficacy, and safety. Hematology Am Soc Hematol Educ Program. 2010;2010:338-347.
    • (2010) Hematology Am Soc Hematol Educ Program , vol.2010 , pp. 338-347
    • Auerbach, M.1    Ballard, H.2
  • 39
    • 84937790511 scopus 로고    scopus 로고
    • PREVENTT: Preoperative intravenous iron to treat anaemia in major surgery: Study protocol for a randomised controlled trial
    • Richards T, Clevenger B, Keidan J, et al. PREVENTT: preoperative intravenous iron to treat anaemia in major surgery: study protocol for a randomised controlled trial. Trials. 2015;16:254.
    • (2015) Trials , vol.16 , pp. 254
    • Richards, T.1    Clevenger, B.2    Keidan, J.3
  • 40
    • 72449156527 scopus 로고    scopus 로고
    • Ferric carboxymaltose in patients with heart failure and iron deficiency
    • Anker SD, Comin Colet J, Filippatos G, et al. Ferric carboxymaltose in patients with heart failure and iron deficiency. N Engl J Med. 2009; 361(25):2436-2448.
    • (2009) N Engl J Med , vol.361 , Issue.25 , pp. 2436-2448
    • Anker, S.D.1    Comin Colet, J.2    Filippatos, G.3
  • 41
    • 84908459097 scopus 로고    scopus 로고
    • Hypersensitivity reactions to intravenous iron: Guidance for risk minimization and management
    • Rampton D, Folkersen J, Fishbane S, et al. Hypersensitivity reactions to intravenous iron: guidance for risk minimization and management. Haematologica. 2014;99(11):1671-1676.
    • (2014) Haematologica , vol.99 , Issue.11 , pp. 1671-1676
    • Rampton, D.1    Folkersen, J.2    Fishbane, S.3


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