메뉴 건너뛰기




Volumn 55, Issue 1, 2017, Pages 159-170

Non-phosphorylated tau as a potential biomarker of Alzheimer's Disease: Analytical and diagnostic characterization

(19)  Lewczuk, Piotr a,k   Lelental, Natalia a   Lachmann, Ingolf b   Holzer, Max c   Flach, Katharina b   Brandner, Sebastian d   Engelborghs, Sebastiaan e,f   Teunissen, Charlotte E g   Zetterberg, Henrik h,i   Molinuevo, José Luis j   Mroczko, Barbara k   Blennow, Kaj h   Popp, Julius l   Parnetti, Lucilla m   Chiasserini, Davide m   Perret Liaudet, Armand n,o   Spitzer, Philipp a   Maler, Juan Manuel a   Kornhuber, Johannes a  


Author keywords

Biomarkers; cerebrospinal fluid; phosphorylation; tau

Indexed keywords

BIOLOGICAL MARKER; EPITOPE; IMMUNOGLOBULIN ANTIBODY; TAU PROTEIN; IMMUNOGLOBULIN G; MAPT PROTEIN, HUMAN;

EID: 84994577084     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-160448     Document Type: Article
Times cited : (28)

References (34)
  • 3
    • 77953759588 scopus 로고    scopus 로고
    • (2009) S3-Leitlinie "Demenzen". http://www.dggpp.de/documents/s3-leitlinie-demenz-kf.pdf.
    • (2009) S3-Leitlinie Demenzen
  • 8
    • 32544435900 scopus 로고    scopus 로고
    • Association between CSF biomarkers and incipient Alzheimer?s disease in patients with mild cognitive impairment: A follow-up study
    • Hansson O, Zetterberg H, Buchhave P, Londos E, Blennow K, Minthon L (2006) Association between CSF biomarkers and incipient Alzheimer?s disease in patients with mild cognitive impairment: A follow-up study. Lancet Neurol 5, 228-234.
    • (2006) Lancet Neurol , vol.5 , pp. 228-234
    • Hansson, O.1    Zetterberg, H.2    Buchhave, P.3    Londos, E.4    Blennow, K.5    Minthon, L.6
  • 9
    • 77949423619 scopus 로고    scopus 로고
    • Cerebrospinal fluid and plasma biomarkers in Alzheimer disease
    • Blennow K, Hampel H, Weiner M, Zetterberg H (2010) Cerebrospinal fluid and plasma biomarkers in Alzheimer disease. Nat Rev Neurol 6, 131-144.
    • (2010) Nat Rev Neurol , vol.6 , pp. 131-144
    • Blennow, K.1    Hampel, H.2    Weiner, M.3    Zetterberg, H.4
  • 10
    • 80051727106 scopus 로고    scopus 로고
    • Neurochemical dementia diagnostics in Alzheimer?s disease: Where are we now and where are we going?
    • Lewczuk P, Kornhuber J (2011) Neurochemical dementia diagnostics in Alzheimer?s disease: Where are we now and where are we going? Expert Rev Proteomics 8, 447-458.
    • (2011) Expert Rev Proteomics , vol.8 , pp. 447-458
    • Lewczuk, P.1    Kornhuber, J.2
  • 11
    • 84947248386 scopus 로고    scopus 로고
    • Amyloid cascade hypo thesis: Pathogenesis and therapeutic strategies in Alzheimer?s disease
    • Barage SH, Sonawane KD (2015) Amyloid cascade hypothesis: Pathogenesis and therapeutic strategies in Alzheimer?s disease. Neuropeptides 52, 1-18.
    • (2015) Neuropeptides , vol.52 , pp. 1-18
    • Barage, S.H.1    Sonawane, K.D.2
  • 12
    • 84922479199 scopus 로고    scopus 로고
    • Inconsistencies and controversies surrounding the amyloid hypothesis of Alzheimer?s disease
    • Morris GP, Clark IA, Vissel B (2014) Inconsistencies and controversies surrounding the amyloid hypothesis of Alzheimer?s disease. Acta Neuropathol Commun 2, 135.
    • (2014) Acta Neuropathol Commun , vol.2 , pp. 135
    • Morris, G.P.1    Clark, I.A.2    Vissel, B.3
  • 13
    • 84930538607 scopus 로고    scopus 로고
    • Tau immunotherapy for Alzheimer?s disease
    • Pedersen JT, Sigurdsson EM (2015) Tau immunotherapy for Alzheimer?s disease. Trends Mol Med 21, 394-402.
    • (2015) Trends Mol Med , vol.21 , pp. 394-402
    • Pedersen, J.T.1    Sigurdsson, E.M.2
  • 14
    • 0029686696 scopus 로고    scopus 로고
    • Evolution of the neuropathology of Alzheimer?s disease
    • Braak H, Braak E (1996) Evolution of the neuropathology of Alzheimer?s disease. Acta Neurol Scand Suppl 165, 3-12.
    • (1996) Acta Neurol Scand Suppl , vol.165 , pp. 3-12
    • Braak, H.1    Braak, E.2
  • 15
    • 0028090656 scopus 로고
    • Abnormally phosphorylated tau protein in Alzheimer?s disease: Heterogeneity of individual regional distribution and relationship to clinical severity
    • Holzer M, Holzapfel HP, Zedlick D, Bruckner MK, Arendt T (1994) Abnormally phosphorylated tau protein in Alzheimer?s disease: Heterogeneity of individual regional distribution and relationship to clinical severity. Neuroscience 63, 499-516.
    • (1994) Neuroscience , vol.63 , pp. 499-516
    • Holzer, M.1    Holzapfel, H.P.2    Zedlick, D.3    Bruckner, M.K.4    Arendt, T.5
  • 17
    • 33746049439 scopus 로고    scopus 로고
    • The German Competence Net Dementias: Standard operating procedures for the neurochemical dementia diagnostics
    • Lewczuk P, Kornhuber J, Wiltfang J (2006) The German Competence Net Dementias: Standard operating procedures for the neurochemical dementia diagnostics. J Neural Transm 113, 1075-1080.
    • (2006) J Neural Transm , vol.113 , pp. 1075-1080
    • Lewczuk, P.1    Kornhuber, J.2    Wiltfang, J.3
  • 18
    • 43249124363 scopus 로고    scopus 로고
    • Microtubule-Associated protein tau in development, degeneration and protection of neurons
    • Wang JZ, Liu F (2008) Microtubule-Associated protein tau in development, degeneration and protection of neurons. Prog Neurobiol 85, 148-175.
    • (2008) Prog Neurobiol , vol.85 , pp. 148-175
    • Wang, J.Z.1    Liu, F.2
  • 20
    • 61849088424 scopus 로고    scopus 로고
    • Tau phosphorylation: The therapeutic challenge for neurodegenerative disease
    • Hanger DP, Anderton BH, Noble W (2009) Tau phosphorylation: The therapeutic challenge for neurodegenerative disease. Trends Mol Med 15, 112-119.
    • (2009) Trends Mol Med , vol.15 , pp. 112-119
    • Hanger, D.P.1    Anderton, B.H.2    Noble, W.3
  • 23
    • 4344626089 scopus 로고    scopus 로고
    • Tau protein phosphorylated at threonine 181 in CSF as a neurochemical biomarker in Alzheimer?s disease: Original data and review of the literature
    • Lewczuk P, Esselmann H, Bibl M, Beck G, Maler JM, Otto M, Kornhuber J, Wiltfang J (2004) Tau protein phosphorylated at threonine 181 in CSF as a neurochemical biomarker in Alzheimer?s disease: Original data and review of the literature. J Mol Neurosci 23, 115-122.
    • (2004) J Mol Neurosci , vol.23 , pp. 115-122
    • Lewczuk, P.1    Esselmann, H.2    Bibl, M.3    Beck, G.4    Maler, J.M.5    Otto, M.6    Kornhuber, J.7    Wiltfang, J.8
  • 24
    • 84922797115 scopus 로고    scopus 로고
    • Clinical utility of cerebrospinal fluid biomarkers in the diagnosis of early Alzheimer?s disease
    • Blennow K, Dubois B, Fagan AM, Lewczuk P, de Leon MJ, Hampel H (2015) Clinical utility of cerebrospinal fluid biomarkers in the diagnosis of early Alzheimer?s disease. Alzheimers Dement 11, 58-69.
    • (2015) Alzheimers Dement , vol.11 , pp. 58-69
    • Blennow, K.1    Dubois, B.2    Fagan, A.M.3    Lewczuk, P.4    De Leon, M.J.5    Hampel, H.6
  • 29
    • 84868677556 scopus 로고    scopus 로고
    • Biochemistry and cell biology of tau protein in neurofibrillary degeneration
    • Mandelkow EM, Mandelkow E (2012) Biochemistry and cell biology of tau protein in neurofibrillary degeneration. Cold Spring Harb Perspect Med 2, a006247.
    • (2012) Cold Spring Harb Perspect Med , vol.2 , pp. a006247
    • Mandelkow, E.M.1    Mandelkow, E.2
  • 30
    • 84908700565 scopus 로고    scopus 로고
    • Amyloid-42/40 CSF concentration ratio in the diagnostics of Alzheimer?s Disease: Validation of two novel assays
    • Lewczuk P, Lelental N, Spitzer P, Maler JM, Kornhuber J (2015) Amyloid-42/40 CSF concentration ratio in the diagnostics of Alzheimer?s Disease: Validation of two novel assays. J Alzheimers Dis 43, 183-191.
    • (2015) J Alzheimers Dis , vol.43 , pp. 183-191
    • Lewczuk, P.1    Lelental, N.2    Spitzer, P.3    Maler, J.M.4    Kornhuber, J.5
  • 33
    • 69549102951 scopus 로고    scopus 로고
    • Neurochemical dementia diagnostics: A simple algorithm for interpretation of the CSF biomarkers
    • Lewczuk P, Zimmermann R, Wiltfang J, Kornhuber J (2009) Neurochemical dementia diagnostics: A simple algorithm for interpretation of the CSF biomarkers. J Neural Transm 116, 1163-1167.
    • (2009) J Neural Transm , vol.116 , pp. 1163-1167
    • Lewczuk, P.1    Zimmermann, R.2    Wiltfang, J.3    Kornhuber, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.