Physiological expression of ampkγ2RG Mutation causes Wolff-Parkinson-White syndrome and induces kidney injury in mice

Journal of Biological Chemistry

Volumn 291, Issue 45, 2016, Pages 23428-23439

  Yang, Xiaodong ^a   Mudgett, John ^a   Bou About, Ghina ^b   Champy, Marie France ^b   Jacobs, Hugues ^b   Monassier, Laurent ^b   Pavlovic, Guillaume ^b   Sorg, Tania ^b   Herault, Yann ^b   Petit Demoulière, Benoit ^b   Lu, Ku ^a   Feng, Wen ^a   Wang, Hongwu ^a   Ma, Li Jun ^a   Askew, Roger ^a   Erion, Mark D ^a   Kelley, David E ^a   Myers, Robert W ^a   Li, Cai ^a   Guan, Hong Ping ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL ORGANS; CELL DEATH; CHEMICAL ACTIVATION; HEART; METABOLISM; PATHOLOGY; PHYSIOLOGY;

AMP-ACTIVATED KINASE; CARDIAC DISORDERS; CARDIAC HYPERTROPHY; IMPAIRED RENAL FUNCTION; KIDNEY DYSFUNCTION; METABOLIC CHANGES; METABOLIC EFFECTS; PHYSIOLOGICAL LEVELS;

MAMMALS;

GLYCOGEN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE;

AMPK GAMMA 2 GENE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; FAT MASS; FATTY LIVER; GENE; GENE EXPRESSION; GENE MUTATION; GENE OVEREXPRESSION; INFLAMMATION; KIDNEY CYST; KIDNEY FUNCTION; KIDNEY INJURY; LIPID DIET; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; WOLFF PARKINSON WHITE SYNDROME; ANIMAL; C57BL MOUSE; DISEASE MODEL; GENE TARGETING; GENETICS; KIDNEY; KIDNEY FAILURE; METABOLISM; MUTATION; PATHOLOGY;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; APOPTOSIS; DISEASE MODELS, ANIMAL; GENE KNOCK-IN TECHNIQUES; INFLAMMATION; KIDNEY; MALE; MICE, INBRED C57BL; MUTATION; RENAL INSUFFICIENCY; WOLFF-PARKINSON-WHITE SYNDROME;

EID: 84994385898     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M116.738591     Document Type: Article

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