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Volumn 36, Issue 11, 2016, Pages 1955-1964

Hypothermia protects brain mitochondrial function from hypoxemia in a murine model of sepsis

Author keywords

hypothermia; Imaging; inflammation; microcirculation; microscopy

Indexed keywords

LIPOPOLYSACCHARIDE; OXYGEN; SODIUM CHLORIDE;

EID: 84994181303     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1177/0271678X15606457     Document Type: Article
Times cited : (25)

References (40)
  • 5
    • 0019932028 scopus 로고
    • Alterations of mitochondrial metabolism and protein concentrations in subacute septicemia
    • Tavakoli H and Mela L. Alterations of mitochondrial metabolism and protein concentrations in subacute septicemia. Infect Immun 1982; 38: 536-541.
    • (1982) Infect Immun , vol.38 , pp. 536-541
    • Tavakoli, H.1    Mela, L.2
  • 6
    • 0037142987 scopus 로고    scopus 로고
    • Association between mitochondrial dysfunction and severity and outcome of septic shock
    • Brealey D, Brand M, Hargreaves I, et al. Association between mitochondrial dysfunction and severity and outcome of septic shock. Lancet 2002; 360: 219-223.
    • (2002) Lancet , vol.360 , pp. 219-223
    • Brealey, D.1    Brand, M.2    Hargreaves, I.3
  • 7
    • 0031572226 scopus 로고    scopus 로고
    • Oxidative metabolism in rat hepatocytes and mitochondria during sepsis
    • Kantrow SP, Taylor DE, Carraway MS, et al. Oxidative metabolism in rat hepatocytes and mitochondria during sepsis. Arch Biochem Biophys 1997; 345: 278-288.
    • (1997) Arch Biochem Biophys , vol.345 , pp. 278-288
    • Kantrow, S.P.1    Taylor, D.E.2    Carraway, M.S.3
  • 8
    • 0015013684 scopus 로고
    • Defective oxidative metabolism of rat liver mitochondria in hemorrhagic and endotoxin shock
    • Mela L, Bacalzo LV and Miller LD. Defective oxidative metabolism of rat liver mitochondria in hemorrhagic and endotoxin shock. Am J Physiol 1971; 220: 571.
    • (1971) Am J Physiol , vol.220 , pp. 571
    • Mela, L.1    Bacalzo, L.V.2    Miller, L.D.3
  • 9
    • 0036174522 scopus 로고    scopus 로고
    • Endotoxininduced mitochondrial damage correlates with impaired respiratory activity
    • Crouser ED, Julian MW, Blaho DV, et al. Endotoxininduced mitochondrial damage correlates with impaired respiratory activity. Crit Care Med 2002; 30: 276-284.
    • (2002) Crit Care Med , vol.30 , pp. 276-284
    • Crouser, E.D.1    Julian, M.W.2    Blaho, D.V.3
  • 10
    • 0020512094 scopus 로고
    • Efficacy of glucocorticoids in preventing mitochondrial metabolic failure in endotoxemia
    • Mela L and Miller LD. Efficacy of glucocorticoids in preventing mitochondrial metabolic failure in endotoxemia. Circ Shock 1983; 10: 371-381.
    • (1983) Circ Shock , vol.10 , pp. 371-381
    • Mela, L.1    Miller, L.D.2
  • 11
    • 3142716777 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in sepsis
    • Brealey D and Singer M. Mitochondrial dysfunction in sepsis. Curr Infect Dis Rep 2003; 5: 365-371.
    • (2003) Curr Infect Dis Rep , vol.5 , pp. 365-371
    • Brealey, D.1    Singer, M.2
  • 12
    • 84874934644 scopus 로고    scopus 로고
    • Microcirculatory alterations in patients with severe sepsis: Impact of time of assessment and relationship with outcome
    • De Backer D, Donadello K, Sakr Y, et al. Microcirculatory alterations in patients with severe sepsis: impact of time of assessment and relationship with outcome. Crit Care Med 2013; 41: 791-799.
    • (2013) Crit Care Med , vol.41 , pp. 791-799
    • De Backer, D.1    Donadello, K.2    Sakr, Y.3
  • 13
    • 84891656914 scopus 로고    scopus 로고
    • Pathophysiology of microcirculatory dysfunction and the pathogenesis of septic shock
    • De Backer D, Cortes DO, Donadello K, et al. Pathophysiology of microcirculatory dysfunction and the pathogenesis of septic shock. Virulence 2014; 5: 73-79.
    • (2014) Virulence , vol.5 , pp. 73-79
    • De Backer, D.1    Cortes, D.O.2    Donadello, K.3
  • 14
    • 27144452656 scopus 로고    scopus 로고
    • Microvascular resuscitation as a therapeutic goal in severe sepsis
    • Bateman RM and Walley KR. Microvascular resuscitation as a therapeutic goal in severe sepsis. Crit Care 2005; 9: S27-S32.
    • (2005) Crit Care , vol.9 , pp. S27-S32
    • Bateman, R.M.1    Walley, K.R.2
  • 15
    • 0028053865 scopus 로고
    • Microvascular perfusion is impaired in a rat model of normotensive sepsis
    • Lam C, Tyml K, Martin C, et al. Microvascular perfusion is impaired in a rat model of normotensive sepsis. J Clin Invest 1994; 94: 2077-2083.
    • (1994) J Clin Invest , vol.94 , pp. 2077-2083
    • Lam, C.1    Tyml, K.2    Martin, C.3
  • 16
    • 27144483559 scopus 로고    scopus 로고
    • Microvascular dysfunction as a cause of organ dysfunction in severe sepsis
    • Vincent JL and De Backer D. Microvascular dysfunction as a cause of organ dysfunction in severe sepsis. Crit Care 2005; 9: S9-S12.
    • (2005) Crit Care , vol.9 , pp. S9-S12
    • Vincent, J.L.1    De Backer, D.2
  • 17
    • 0030049328 scopus 로고    scopus 로고
    • Skeletal muscle microvascular blood flow and oxygen transport in patients with severe sepsis
    • Neviere R, Mathieu D, Chagnon JL, et al. Skeletal muscle microvascular blood flow and oxygen transport in patients with severe sepsis. Am J Respir Crit Care Med 1996; 153: 191-195.
    • (1996) Am J Respir Crit Care Med , vol.153 , pp. 191-195
    • Neviere, R.1    Mathieu, D.2    Chagnon, J.L.3
  • 18
    • 0029957187 scopus 로고    scopus 로고
    • Microcirculatory changes in rat skeletal muscle in sepsis
    • Piper RD, Pitt-Hyde M, Li FY, et al. Microcirculatory changes in rat skeletal muscle in sepsis. Am J Respir Crit Care Med 1996; 154: 931-937.
    • (1996) Am J Respir Crit Care Med , vol.154 , pp. 931-937
    • Piper, R.D.1    Pitt-Hyde, M.2    Li, F.Y.3
  • 19
    • 0036079693 scopus 로고    scopus 로고
    • Effect of a maldistribution of microvascular blood flow on capillary O-2 extraction in sepsis
    • Ellis CG, Bateman RM, Sharpe MD, et al. Effect of a maldistribution of microvascular blood flow on capillary O-2 extraction in sepsis. Am J Physiol-Heart C 2002; 282: H156-H164.
    • (2002) Am J Physiol-Heart C , vol.282 , pp. H156-H164
    • Ellis, C.G.1    Bateman, R.M.2    Sharpe, M.D.3
  • 20
    • 0030997422 scopus 로고    scopus 로고
    • N-Acetylcysteine attenuates endotoxin-induced leukocyte endothelial cell adhesion and macromolecular leakage in vivo
    • Schmidt H, Schmidt W, Muller T, et al. N-Acetylcysteine attenuates endotoxin-induced leukocyte endothelial cell adhesion and macromolecular leakage in vivo. Crit Care Med 1997; 25: 858-863.
    • (1997) Crit Care Med , vol.25 , pp. 858-863
    • Schmidt, H.1    Schmidt, W.2    Muller, T.3
  • 21
    • 0032790876 scopus 로고    scopus 로고
    • Microcirculatory oxygenation and shunting in sepsis and shock
    • Ince C and Sinaasappel M. Microcirculatory oxygenation and shunting in sepsis and shock. Crit Care Med 1999; 27: 1369-1377.
    • (1999) Crit Care Med , vol.27 , pp. 1369-1377
    • Ince, C.1    Sinaasappel, M.2
  • 22
    • 0029746049 scopus 로고    scopus 로고
    • Heterogeneity of gut capillary transit times and impaired gut oxygen extraction in endotoxemic pigs
    • Humer MF, Phang PT, Friesen BP, et al. Heterogeneity of gut capillary transit times and impaired gut oxygen extraction in endotoxemic pigs. J Appl Physiol 1996; 81: 895-904.
    • (1996) J Appl Physiol , vol.81 , pp. 895-904
    • Humer, M.F.1    Phang, P.T.2    Friesen, B.P.3
  • 23
    • 0024673023 scopus 로고
    • Cerebral blood-flow is reduced in patients with sepsis syndrome
    • Bowton DL, Bertels NH, Prough DS, et al. Cerebral blood-flow is reduced in patients with sepsis syndrome. Crit Care Med 1989; 17: 399-403.
    • (1989) Crit Care Med , vol.17 , pp. 399-403
    • Bowton, D.L.1    Bertels, N.H.2    Prough, D.S.3
  • 24
    • 0025878179 scopus 로고
    • Cerebral-circulation and metabolism in patients with septic encephalopathy
    • Maekawa T, Fujii Y, Sadamitsu D, et al. Cerebral-circulation and metabolism in patients with septic encephalopathy. Am J Emerg Med 1991; 9: 139-143.
    • (1991) Am J Emerg Med , vol.9 , pp. 139-143
    • Maekawa, T.1    Fujii, Y.2    Sadamitsu, D.3
  • 25
    • 10644281080 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in septic shock and multiple organ dysfunction syndrome
    • Crouser ED. Mitochondrial dysfunction in septic shock and multiple organ dysfunction syndrome. Mitochondrion 2004; 4: 729-741.
    • (2004) Mitochondrion , vol.4 , pp. 729-741
    • Crouser, E.D.1
  • 26
    • 77954923610 scopus 로고    scopus 로고
    • Cerebral microcirculation is impaired during sepsis: An experimental study
    • R
    • Taccone FS, Su FH, Pierrakos C, et al. Cerebral microcirculation is impaired during sepsis: an experimental study. Crit Care 2010; 14: R:140.
    • (2010) Crit Care , vol.14 , pp. 140
    • Taccone, F.S.1    Su, F.H.2    Pierrakos, C.3
  • 27
    • 0030756558 scopus 로고    scopus 로고
    • Cerebral blood flow during experimental endotoxemia in volunteers
    • Pollard V, Prough DS, Deyo DJ, et al. Cerebral blood flow during experimental endotoxemia in volunteers. Crit Care Med 1997; 25: 1700-1706.
    • (1997) Crit Care Med , vol.25 , pp. 1700-1706
    • Pollard, V.1    Prough, D.S.2    Deyo, D.J.3
  • 28
    • 0021395815 scopus 로고
    • Cardiac-output and redistribution of organ blood-flow in hypermetabolic sepsis
    • Lang CH, Bagby GJ, Ferguson JL, et al. Cardiac-output and redistribution of organ blood-flow in hypermetabolic sepsis. Am J Physiol 1984; 246: R331-R337.
    • (1984) Am J Physiol , vol.246 , pp. R331-R337
    • Lang, C.H.1    Bagby, G.J.2    Ferguson, J.L.3
  • 29
    • 0041866144 scopus 로고    scopus 로고
    • Induced hypothermia in critical care medicine: A review
    • Bernard SA and Buist M. Induced hypothermia in critical care medicine: A review. Crit Care Med 2003; 31: 2041-2051.
    • (2003) Crit Care Med , vol.31 , pp. 2041-2051
    • Bernard, S.A.1    Buist, M.2
  • 30
    • 62849110915 scopus 로고    scopus 로고
    • Therapeutic hypothermia and controlled normothermia in the intensive care unit: Practical considerations, side effects, and cooling methods
    • Polderman KH and Herold I. Therapeutic hypothermia and controlled normothermia in the intensive care unit: Practical considerations, side effects, and cooling methods. Crit Care Med 2009; 37: 1101-1120.
    • (2009) Crit Care Med , vol.37 , pp. 1101-1120
    • Polderman, K.H.1    Herold, I.2
  • 31
    • 84888588214 scopus 로고    scopus 로고
    • Induced hypothermia in severe bacterial meningitis: A randomized clinical trial
    • Mourvillier B, Tubach F, van de Beek D, et al. Induced hypothermia in severe bacterial meningitis: A randomized clinical trial. J Am Med Assoc 2013; 310: 2174-2183.
    • (2013) J Am Med Assoc , vol.310 , pp. 2174-2183
    • Mourvillier, B.1    Tubach, F.2    Van De Beek, D.3
  • 33
    • 84994090139 scopus 로고    scopus 로고
    • In vivo imaging of flavoprotein fluorescence during hypoxia reveals the importance of direct arterial oxygen supply to cerebral cortex tissue
    • in press
    • Chisholm KI, Ida KK, Davies AL, et al. In vivo imaging of flavoprotein fluorescence during hypoxia reveals the importance of direct arterial oxygen supply to cerebral cortex tissue. Oxygen Transport to Tissue XXXVII (in press) 2015.
    • (2015) Oxygen Transport to Tissue XXXVII
    • Chisholm, K.I.1    Ida, K.K.2    Davies, A.L.3
  • 34
    • 3042640876 scopus 로고    scopus 로고
    • Flavoprotein autofluorescence imaging of neuronal activation in the cerebellar cortex in vivo
    • Reinert KC, Dunbar RL, Gao WC, et al. Flavoprotein autofluorescence imaging of neuronal activation in the cerebellar cortex in vivo. J Neurophysiol 2004; 92: 199-211.
    • (2004) J Neurophysiol , vol.92 , pp. 199-211
    • Reinert, K.C.1    Dunbar, R.L.2    Gao, W.C.3
  • 35
    • 35848953199 scopus 로고    scopus 로고
    • Flavoprotein autofluorescence imaging in the cerebellar cortex in vivo
    • Reinert KC, Gao WC, Chen G, et al. Flavoprotein autofluorescence imaging in the cerebellar cortex in vivo. J Neurosci Res 2007; 85: 3221-3232.
    • (2007) J Neurosci Res , vol.85 , pp. 3221-3232
    • Reinert, K.C.1    Gao, W.C.2    Chen, G.3
  • 36
    • 68049089963 scopus 로고    scopus 로고
    • Microcirculation and mitochondria in sepsis: Getting out of breath
    • Balestra GM, Legrand M and Ince C. Microcirculation and mitochondria in sepsis: getting out of breath. Curr Opin Anaesthesiol 2009; 22: 184-190.
    • (2009) Curr Opin Anaesthesiol , vol.22 , pp. 184-190
    • Balestra, G.M.1    Legrand, M.2    Ince, C.3
  • 37
    • 0014085989 scopus 로고
    • Flavoproteins of the mitochondrial respiratory chain
    • Chance B, Ernster L, Garland PB, et al. Flavoproteins of the mitochondrial respiratory chain. Proc Natl Acad Sci U S A 1967; 57: 1498-1505.
    • (1967) Proc Natl Acad Sci U S A , vol.57 , pp. 1498-1505
    • Chance, B.1    Ernster, L.2    Garland, P.B.3
  • 38
    • 78650903448 scopus 로고    scopus 로고
    • Twophoton NADH imaging exposes boundaries of oxygen diffusion in cortical vascular supply regions
    • Kasischke KA, Lambert EM, Panepento B, et al. Twophoton NADH imaging exposes boundaries of oxygen diffusion in cortical vascular supply regions. J Cereb Blood Flow Metab 2011; 31: 68-81.
    • (2011) J Cereb Blood Flow Metab , vol.31 , pp. 68-81
    • Kasischke, K.A.1    Lambert, E.M.2    Panepento, B.3
  • 40
    • 34447623219 scopus 로고    scopus 로고
    • Bench-To-bedside review: Potential strategies to protect or reverse mitochondrial dysfunction in sepsis-induced organ failure
    • Protti A and Singer M. Bench-To-bedside review: Potential strategies to protect or reverse mitochondrial dysfunction in sepsis-induced organ failure. Crit Care 2006; 10: 228.
    • (2006) Crit Care , vol.10 , pp. 228
    • Protti, A.1    Singer, M.2


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