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Volumn 7, Issue 40, 2016, Pages 66202-66211

Metformin use improves survival of diabetic liver cancer patients: Systematic review and meta-analysis

Author keywords

Diabetes mellitus; Liver cancer; Meta analysis; Metformin; Survival

Indexed keywords

METFORMIN; ANTIDIABETIC AGENT;

EID: 84994168630     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.11033     Document Type: Article
Times cited : (62)

References (53)
  • 1
    • 0035200712 scopus 로고    scopus 로고
    • Trends in survival of patients with hepatocellular carcinoma between 1977 and 1996 in the United States
    • El-Serag HB, Mason AC and Key C. Trends in survival of patients with hepatocellular carcinoma between 1977 and 1996 in the United States. Hepatology (Baltimore, Md). 2001; 33:62-65.
    • (2001) Hepatology (Baltimore, Md) , vol.33 , pp. 62-65
    • El-Serag, H.B.1    Mason, A.C.2    Key, C.3
  • 2
    • 20444494440 scopus 로고    scopus 로고
    • Therapy insight: Influence of type 2 diabetes on the development, treatment and outcomes of cancer
    • Richardson LC and Pollack LA. Therapy insight: Influence of type 2 diabetes on the development, treatment and outcomes of cancer. Nature clinical practice Oncology. 2005; 2:48-53.
    • (2005) Nature clinical practice Oncology , vol.2 , pp. 48-53
    • Richardson, L.C.1    Pollack, L.A.2
  • 3
    • 58049192725 scopus 로고    scopus 로고
    • Long-term all-cause mortality in cancer patients with preexisting diabetes mellitus: a systematic review and meta-analysis
    • Barone BB, Yeh HC, Snyder CF, Peairs KS, Stein KB, Derr RL, WolffAC and Brancati FL. Long-term all-cause mortality in cancer patients with preexisting diabetes mellitus: a systematic review and meta-analysis. Jama. 2008; 300:2754-2764.
    • (2008) Jama , vol.300 , pp. 2754-2764
    • Barone, B.B.1    Yeh, H.C.2    Snyder, C.F.3    Peairs, K.S.4    Stein, K.B.5    Derr, R.L.6    Wolff, A.C.7    Brancati, F.L.8
  • 6
    • 84957665963 scopus 로고    scopus 로고
    • Metformin may reduce oral cancer risk in patients with type 2 diabetes
    • Tseng CH. Metformin may reduce oral cancer risk in patients with type 2 diabetes. Oncotarget. 2016; 7:2000-2008 doi: 10.18632/oncotarget.6626.
    • (2016) Oncotarget , vol.7 , pp. 2000-2008
    • Tseng, C.H.1
  • 8
    • 84890016628 scopus 로고    scopus 로고
    • Metformin is associated with survival benefit in cancer patients with concurrent type 2 diabetes: a systematic review and metaanalysis
    • Yin M, Zhou J, Gorak EJ and Quddus F. Metformin is associated with survival benefit in cancer patients with concurrent type 2 diabetes: a systematic review and metaanalysis. The oncologist. 2013; 18:1248-1255.
    • (2013) The oncologist , vol.18 , pp. 1248-1255
    • Yin, M.1    Zhou, J.2    Gorak, E.J.3    Quddus, F.4
  • 9
    • 84959169777 scopus 로고    scopus 로고
    • Metformin Is Associated With Slightly Reduced Risk of Colorectal Cancer and Moderate Survival Benefits in Diabetes Mellitus: A Meta-Analysis
    • He XK, Su TT, Si JM and Sun LM. Metformin Is Associated With Slightly Reduced Risk of Colorectal Cancer and Moderate Survival Benefits in Diabetes Mellitus: A Meta-Analysis. Medicine. 2016; 95:e2749.
    • (2016) Medicine , vol.95
    • He, X.K.1    Su, T.T.2    Si, J.M.3    Sun, L.M.4
  • 11
    • 84946542679 scopus 로고    scopus 로고
    • Metformin Use Is Associated With Better Survival of Breast Cancer Patients With Diabetes: A Meta-Analysis
    • Xu H, Chen K, Jia X, Tian Y, Dai Y, Li D, Xie J, Tao M and Mao Y. Metformin Use Is Associated With Better Survival of Breast Cancer Patients With Diabetes: A Meta-Analysis. The oncologist. 2015; 20:1236-1244.
    • (2015) The oncologist , vol.20 , pp. 1236-1244
    • Xu, H.1    Chen, K.2    Jia, X.3    Tian, Y.4    Dai, Y.5    Li, D.6    Xie, J.7    Tao, M.8    Mao, Y.9
  • 13
    • 84876334434 scopus 로고    scopus 로고
    • Association of metformin use with cancer incidence and mortality: a metaanalysis
    • Zhang P, Li H, Tan X, Chen L and Wang S. Association of metformin use with cancer incidence and mortality: a metaanalysis. Cancer epidemiology. 2013; 37:207-218.
    • (2013) Cancer epidemiology , vol.37 , pp. 207-218
    • Zhang, P.1    Li, H.2    Tan, X.3    Chen, L.4    Wang, S.5
  • 15
    • 84878933932 scopus 로고    scopus 로고
    • Pharmacological activation of AMPK suppresses inflammatory response evoked by IL-6 signalling in mouse liver and in human hepatocytes
    • Nerstedt A, Cansby E, Amrutkar M, Smith U and Mahlapuu M. Pharmacological activation of AMPK suppresses inflammatory response evoked by IL-6 signalling in mouse liver and in human hepatocytes. Molecular and cellular endocrinology. 2013; 375:68-78.
    • (2013) Molecular and cellular endocrinology , vol.375 , pp. 68-78
    • Nerstedt, A.1    Cansby, E.2    Amrutkar, M.3    Smith, U.4    Mahlapuu, M.5
  • 16
    • 84946414610 scopus 로고    scopus 로고
    • Metformin: A Novel but Controversial Drug in Cancer Prevention and Treatment
    • Sui X, Xu Y, Wang X, Han W, Pan H and Xiao M. Metformin: A Novel but Controversial Drug in Cancer Prevention and Treatment. Molecular Pharmaceutics. 2015; 12:3783-3791.
    • (2015) Molecular Pharmaceutics , vol.12 , pp. 3783-3791
    • Sui, X.1    Xu, Y.2    Wang, X.3    Han, W.4    Pan, H.5    Xiao, M.6
  • 17
    • 84865131639 scopus 로고    scopus 로고
    • In vitro and in vivo antitumoral action of metformin on hepatocellular carcinoma
    • Qu Z, Zhang Y, Liao M, Chen Y, Zhao J and Pan Y. In vitro and in vivo antitumoral action of metformin on hepatocellular carcinoma. Hepatology research. 2012; 42:922-933.
    • (2012) Hepatology research , vol.42 , pp. 922-933
    • Qu, Z.1    Zhang, Y.2    Liao, M.3    Chen, Y.4    Zhao, J.5    Pan, Y.6
  • 18
    • 79954478103 scopus 로고    scopus 로고
    • Metformin associated with lower mortality in diabetic patients with early stage hepatocellular carcinoma after radiofrequency ablation
    • Chen TM, Lin CC, Huang PT and Wen CF. Metformin associated with lower mortality in diabetic patients with early stage hepatocellular carcinoma after radiofrequency ablation. Journal of gastroenterology and hepatology. 2011; 26:858-865.
    • (2011) Journal of gastroenterology and hepatology , vol.26 , pp. 858-865
    • Chen, T.M.1    Lin, C.C.2    Huang, P.T.3    Wen, C.F.4
  • 21
    • 84994148532 scopus 로고    scopus 로고
    • Metformin Use Reduces Intrahepatic Cholangiocarcinoma Risk in Patients With Diabetes but Does Not Improve Survival of Cholangiocarcinoma
    • Yang Z, Zhang X, Roberts LR and Chaiteerakij R. Metformin Use Reduces Intrahepatic Cholangiocarcinoma Risk in Patients With Diabetes but Does Not Improve Survival of Cholangiocarcinoma. Gastroenterology. 2015; 148:1029-1030.
    • (2015) Gastroenterology , vol.148 , pp. 1029-1030
    • Yang, Z.1    Zhang, X.2    Roberts, L.R.3    Chaiteerakij, R.4
  • 22
    • 84994172161 scopus 로고    scopus 로고
    • Metformin use improves survival of cholangiocarcinoma (CC) patients with type II diabetes (DM)
    • Chaiteerakij R, Baichoo E and Roberts LR. Metformin use improves survival of cholangiocarcinoma (CC) patients with type II diabetes (DM). Hepatology (Baltimore, Md). 2013; 58:331-332.
    • (2013) Hepatology (Baltimore, Md) , vol.58 , pp. 331-332
    • Chaiteerakij, R.1    Baichoo, E.2    Roberts, L.R.3
  • 24
    • 84859029647 scopus 로고    scopus 로고
    • Mortality after incident cancer in people with and without type 2 diabetes: impact of metformin on survival
    • Currie CJ, Poole CD, Jenkins-Jones S, Gale EA, Johnson JA and Morgan CL. Mortality after incident cancer in people with and without type 2 diabetes: impact of metformin on survival. Diabetes care. 2012; 35:299-304.
    • (2012) Diabetes care , vol.35 , pp. 299-304
    • Currie, C.J.1    Poole, C.D.2    Jenkins-Jones, S.3    Gale, E.A.4    Johnson, J.A.5    Morgan, C.L.6
  • 31
    • 84861127026 scopus 로고    scopus 로고
    • Metformin use is associated with better survival of diabetic patients with pancreatic cancer
    • Sadeghi N, Abbruzzese JL, Yeung SC, Hassan M and Li D. Metformin use is associated with better survival of diabetic patients with pancreatic cancer. Clinical cancer research. 2012; 18:2905-2912.
    • (2012) Clinical cancer research , vol.18 , pp. 2905-2912
    • Sadeghi, N.1    Abbruzzese, J.L.2    Yeung, S.C.3    Hassan, M.4    Li, D.5
  • 32
    • 84882273707 scopus 로고    scopus 로고
    • A cohort study of metformin exposure and survival in patients with stage I-III colorectal cancer
    • Spillane S, Bennett K, Sharp L and Barron TI. A cohort study of metformin exposure and survival in patients with stage I-III colorectal cancer. Cancer epidemiology, biomarkers & prevention. 2013; 22:1364-1373.
    • (2013) Cancer epidemiology, biomarkers & prevention , vol.22 , pp. 1364-1373
    • Spillane, S.1    Bennett, K.2    Sharp, L.3    Barron, T.I.4
  • 37
    • 84857640868 scopus 로고    scopus 로고
    • The insulin and insulin-like growth factor receptor family in neoplasia: an update
    • Pollak M. The insulin and insulin-like growth factor receptor family in neoplasia: an update. Nature reviews Cancer. 2012; 12:159-169.
    • (2012) Nature reviews Cancer , vol.12 , pp. 159-169
    • Pollak, M.1
  • 40
    • 84861197159 scopus 로고    scopus 로고
    • Hepatocellular carcinoma in non-alcoholic fatty liver disease: an emerging menace
    • Baffy G, Brunt EM and Caldwell SH. Hepatocellular carcinoma in non-alcoholic fatty liver disease: an emerging menace. Journal of hepatology. 2012; 56:1384-1391.
    • (2012) Journal of hepatology , vol.56 , pp. 1384-1391
    • Baffy, G.1    Brunt, E.M.2    Caldwell, S.H.3
  • 41
    • 84901301642 scopus 로고    scopus 로고
    • Diabetes mellitus and poorer prognosis in hepatocellular carcinoma: a systematic review and meta-analysis
    • Wang YG, Wang P, Wang B, Fu ZJ, Zhao WJ and Yan SL. Diabetes mellitus and poorer prognosis in hepatocellular carcinoma: a systematic review and meta-analysis. PloS one. 2014; 9:e95485.
    • (2014) PloS one , vol.9
    • Wang, Y.G.1    Wang, P.2    Wang, B.3    Fu, Z.J.4    Zhao, W.J.5    Yan, S.L.6
  • 42
    • 38149091762 scopus 로고    scopus 로고
    • Analysis of recurrence pattern and its influence on survival outcome after radiofrequency ablation of hepatocellular carcinoma
    • Ng KK, Poon RT, Lo CM, Yuen J, Tso WK and Fan ST. Analysis of recurrence pattern and its influence on survival outcome after radiofrequency ablation of hepatocellular carcinoma. Journal of gastrointestinal surgery. 2008; 12:183-191.
    • (2008) Journal of gastrointestinal surgery , vol.12 , pp. 183-191
    • Ng, K.K.1    Poon, R.T.2    Lo, C.M.3    Yuen, J.4    Tso, W.K.5    Fan, S.T.6
  • 43
    • 13844280344 scopus 로고    scopus 로고
    • Early-stage hepatocellular carcinoma in patients with cirrhosis: long-term results of percutaneous image-guided radiofrequency ablation
    • Lencioni R, Cioni D, Crocetti L, Franchini C, Pina CD, Lera J and Bartolozzi C. Early-stage hepatocellular carcinoma in patients with cirrhosis: long-term results of percutaneous image-guided radiofrequency ablation. Radiology. 2005; 234:961-967.
    • (2005) Radiology , vol.234 , pp. 961-967
    • Lencioni, R.1    Cioni, D.2    Crocetti, L.3    Franchini, C.4    Pina, C.D.5    Lera, J.6    Bartolozzi, C.7
  • 44
    • 37149005149 scopus 로고    scopus 로고
    • Initial treatment response is essential to improve survival in patients with hepatocellular carcinoma who underwent curative radiofrequency ablation therapy
    • Takahashi S, Kudo M, Chung H, Inoue T, Ishikawa E, Kitai S, Tatsumi C, Ueda T, Minami Y, Ueshima K and Haji S. Initial treatment response is essential to improve survival in patients with hepatocellular carcinoma who underwent curative radiofrequency ablation therapy. Oncology. 2007; 72:98-103.
    • (2007) Oncology , vol.72 , pp. 98-103
    • Takahashi, S.1    Kudo, M.2    Chung, H.3    Inoue, T.4    Ishikawa, E.5    Kitai, S.6    Tatsumi, C.7    Ueda, T.8    Minami, Y.9    Ueshima, K.10    Haji, S.11
  • 46
    • 77951818071 scopus 로고    scopus 로고
    • Diabetes, insulin use, and cancer risk: are observational studies part of the solution-or part of the problem?
    • Johnson JA and Gale EA. Diabetes, insulin use, and cancer risk: are observational studies part of the solution-or part of the problem? Diabetes. 2010; 59:1129-1131.
    • (2010) Diabetes , vol.59 , pp. 1129-1131
    • Johnson, J.A.1    Gale, E.A.2
  • 47
    • 84884500518 scopus 로고    scopus 로고
    • Diabetes treatments and cancer risk: the importance of considering aspects of drug exposure
    • Walker JJ, Johnson JA and Wild SH. Diabetes treatments and cancer risk: the importance of considering aspects of drug exposure. The lancet Diabetes & endocrinology. 2013; 1:132-139.
    • (2013) The lancet Diabetes & endocrinology , vol.1 , pp. 132-139
    • Walker, J.J.1    Johnson, J.A.2    Wild, S.H.3
  • 48
    • 77957661914 scopus 로고    scopus 로고
    • Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses
    • Stang A. Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. European journal of epidemiology. 2010; 25:603-605.
    • (2010) European journal of epidemiology , vol.25 , pp. 603-605
    • Stang, A.1
  • 49
    • 84979645289 scopus 로고    scopus 로고
    • Enhanced secondary analysis of survival data: reconstructing the data from published Kaplan-Meier survival curves
    • Guyot P, Ades AE, Ouwens MJ and Welton NJ. Enhanced secondary analysis of survival data: reconstructing the data from published Kaplan-Meier survival curves. BMC medical research methodology. 2012; 12:9.
    • (2012) BMC medical research methodology , vol.12 , pp. 9
    • Guyot, P.1    Ades, A.E.2    Ouwens, M.J.3    Welton, N.J.4
  • 51
    • 84959801619 scopus 로고
    • Statistical aspects of the analysis of data from retrospective studies of disease
    • Mantel N and Haenszel W. Statistical aspects of the analysis of data from retrospective studies of disease. Journal of the National Cancer Institute. 1959; 22:719-748.
    • (1959) Journal of the National Cancer Institute , vol.22 , pp. 719-748
    • Mantel, N.1    Haenszel, W.2
  • 53
    • 0028659004 scopus 로고
    • Operating characteristics of a rank correlation test for publication bias
    • Begg CB and Mazumdar M. Operating characteristics of a rank correlation test for publication bias. Biometrics. 1994; 50:1088-1101.
    • (1994) Biometrics , vol.50 , pp. 1088-1101
    • Begg, C.B.1    Mazumdar, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.