Ketamine versus aminophylline for acute asthma in children: A randomized, controlled trial

Annals of Thoracic Medicine

Volumn 11, Issue 4, 2016, Pages 283-288

  Tiwari, Abhimanyu ^a   Guglani, Vishal ^a   Jat, Kana Ram ^a,b  

^a GOVERNMENT MEDICAL COLLEGE AND HOSPITAL   (India)

^b ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Acute asthma; aminophylline; children; ketamine

Indexed keywords

AMINOPHYLLINE; KETAMINE;

ACUTE DISEASE; ARTICLE; ARTIFICIAL VENTILATION; ASTHMA; CARBON DIOXIDE TENSION; CHILD; CLINICAL ARTICLE; COMPARATIVE EFFECTIVENESS; CONTINUOUS INFUSION; CONTROLLED STUDY; DISEASE EXACERBATION; DRUG EFFICACY; DRUG SAFETY; FEMALE; HOSPITALIZATION; HUMAN; HYPERTENSION; INTERVENTION STUDY; MALE; OUTCOME ASSESSMENT; OXYGEN TENSION; PEDIATRIC RESPIRATORY ASSESSMENT MEASURE SCORE; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY TRACT DISEASE ASSESSMENT; TACHYCARDIA; TREATMENT RESPONSE; VOMITING;

EID: 84994151979     PISSN: 18171737     EISSN: 19983557     Source Type: Journal    
DOI: 10.4103/1817-1737.191874     Document Type: Article

References (21)

1. GINA Report, Global Strategy for Asthma Management and Prevention. Global Initiative for Asthma - GINA; 2015. Available from: http://www.ginasthma.org/gina-report-global-strategy-for-asthma-management-and-prevention/. [Last cited on 2016 Mar 27].
2. BTS-SIGN Asthma Guideline-2014. Available from: https://www.brit-thoracic.org.uk/document-library/clinical-information/asthma/btssign-asthma-guideline-2014/. [Last cited on 2016 Mar 27].
3. Expert Panel Report 3: Guidelines for the Diagnosis and Management of Asthma. Available from: http://www.nhlbi.nih.gov/files/docs/guidelines/asthgdln.pdf. [Last cited on 2016 Mar 27].
4. Howes MC. Ketamine for paediatric sedation/analgesia in the emergency department. Emerg Med J 2004;21:275-80.
5. Roback MG, Wathen JE, Bajaj L, Bothner JP. Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: A comparison of common parenteral drugs. Acad Emerg Med 2005;12:508-13.
6. Strube PJ, Hallam PL. Ketamine by continuous infusion in status asthmaticus. Anaesthesia 1986;41:1017-9.
7. Petrillo TM, Fortenberry JD, Linzer JF, Simon HK. Emergency department use of ketamine in pediatric status asthmaticus. J Asthma 2001;38:657-64.
8. Gateau O, Bourgain JL, Gaudy JH, Benveniste J. Effects of ketamine on isolated human bronchial preparations. Br J Anaesth 1989;63:692-5.
9. Youssef-Ahmed MZ, Silver P, Nimkoff L, Sagy M. Continuous infusion of ketamine in mechanically ventilated children with refractory bronchospasm. Intensive Care Med 1996;22:972-6.
10. Denmark TK, Crane HA, Brown L. Ketamine to avoid mechanical ventilation in severe pediatric asthma. J Emerg Med 2006;30:163-6.
11. Essayan DM. Cyclic nucleotide phosphodiesterases. J Allergy Clin Immunol 2001;108:671-80.
12. Mitra A, Bassler D, Goodman K, Lasserson TJ, Ducharme FM. Intravenous aminophylline for acute severe asthma in children over two years receiving inhaled bronchodilators. Cochrane Database Syst Rev 2005:CD001276.
13. Ducharme FM, Chalut D, Plotnick L, Savdie C, Kudirka D, Zhang X, et al. The Pediatric Respiratory Assessment Measure: A valid clinical score for assessing acute asthma severity from toddlers to teenagers. J Pediatr 2008;152:476-80, 480.e1.
14. Betts EK, Parkin CE. Use of ketamine in an asthmatic child: A case report. Anesth Analg 1971;50:420-1.
15. Fischer MM. Ketamine hydrochloride in severe bronchospasm. Anaesthesia 1977;32:771-2.
16. Rock MJ, Reyes de la Rocha S, L'Hommedieu CS, Truemper E. Use of ketamine in asthmatic children to treat respiratory failure refractory to conventional therapy. Crit Care Med 1986;14:514-6.
17. Allen JY, Macias CG. The efficacy of ketamine in pediatric emergency department patients who present with acute severe asthma. Ann Emerg Med 2005;46:43-50.
18. Howton JC, Rose J, Duffy S, Zoltanski T, Levitt MA. Randomized, double-blind, placebo-controlled trial of intravenous ketamine in acute asthma. Ann Emerg Med 1996;27:170-5.
19. Hemmingsen C, Nielsen PK, Odorico J. Ketamine in the treatment of bronchospasm during mechanical ventilation. Am J Emerg Med 1994;12:417-20.
20. Jat KR, Chawla D. Ketamine for management of acute exacerbations of asthma in children. In: The Cochrane Collaboration, editor. Cochrane Database of Systematic Reviews. Chichester, UK: John Wiley and Sons, Ltd; 2012. Available from: http://www.doi.wiley.com/10.1002/14651858.CD009293.pub2. [Last cited on 2016 Mar 26].
21. Goyal S, Agrawal A. Ketamine in status asthmaticus: A review. Indian J Crit Care Med 2013;17:154-61.