High-sensitive cardiac troponin T (hs-cTnT) assay as serum biomarker to predict cardiac risk in myotonic dystrophy: A case-control study

Clinica Chimica Acta

Volumn 463, Issue , 2016, Pages 122-128

  Valaperta, Rea ^a   Gaeta, Maddalena ^b   Cardani, Rosanna ^a   Lombardi, Fortunata ^a   Rampoldi, Benedetta ^a   De Siena, Claudia ^a   Mori, Francesca ^a   Fossati, Barbara ^c   Gaia, Paola ^a   Ferraro, Ottavia Eleonora ^b   Villani, Simona ^b   Iachettini, Sara ^a   Piccoli, Marco ^a   Cirillo, Federica ^a   Pusineri, Enrico ^a   Meola, Giovanni ^a,c   Costa, Elena ^a  

^a IRCCS POLICLINICO SAN DONATO   (Italy)

^b UNIVERSITY OF PAVIA   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

Author keywords

Cardiac involvement; hs cTnI; hs cTnT; Myotonic dystrophy

Indexed keywords

AMINO TERMINAL PRO BRAIN NATRIURETIC PEPTIDE; BIOLOGICAL MARKER; CREATINE KINASE; MESSENGER RNA; TROPONIN T;

ADULT; ARTICLE; CARDIOVASCULAR RISK; CASE CONTROL STUDY; CLINICAL FEATURE; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE DURATION; FEMALE; HEART EJECTION FRACTION; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MYOTONIC DYSTROPHY; ONSET AGE; PREDICTION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; QRS INTERVAL; RISK ASSESSMENT; RISK FACTOR; SENSITIVITY ANALYSIS; BLOOD; COMPLICATION; HEART DISEASES; MIDDLE AGED;

ADULT; BIOMARKERS; CASE-CONTROL STUDIES; FEMALE; HEART DISEASES; HUMANS; MALE; MIDDLE AGED; MYOTONIC DYSTROPHY; RISK FACTORS; TROPONIN T;

EID: 84993993198     PISSN: 00098981     EISSN: 18733492     Source Type: Journal    
DOI: 10.1016/j.cca.2016.10.026     Document Type: Article

References (29)

1. [1] Meola, G., Sansone, V., Marinou, K., Cotelli, M., Moxley, R.T. III, Thornton, C.A., et al. Proximal myotonic myopathy: a syndrome with a favourable prognosis?. J. Neurol. Sci. 193 (2002), 89–96.
2. [2] Flachenecker, P., Schneider, C., Cursiefen, S., Ricker, K., Toyka, K.V., Reiners, K., Assessment of cardiovascular autonomic function in myotonic dystrophy type 2 (DM2/PROMM). Neuromuscul. Disord. 13 (2003), 289–293.
3. [3] Day, J.W., Roelofs, R., Leroy, B., Pech, I., Benzow, K., Ranum, L.P., Clinical and genetic characteristics of a five-generation family with a novel form of myotonic dystrophy (DM2). Neuromuscul. Disord. 9 (1999), 19–27.
4. [4] Moxley, R.T., Meola, G., Udd, B., Ricker, K., Report of the 84th ENMC workshop: PROMM (proximal myotonic myopathy) and other myotonic dystrophy-like syndromes: 2nd workshop. 13–15th October, 2000. Loosdrecht, The Netherlands. Neuromuscul. Disord. 12 (2002), 306–317.
5. [5] Thygesen, K., Alpert, J.S., White, H.D., Joint ESC/ACCF/AHA/WHF Task Force for the Redefinition of Myocardial Infarction, Jaffe, A.S., Apple, F.S., et al. Universal definition of myocardial infarction. Circulation 116 (2007), 2634–2653.
6. [6] Thygesen, K., Mair, J., Katus, H., Plebani, M., Venge, P., Collinson, P., et al. Recommendations for the use of cardiac troponin measurement in acute cardiac care. Eur. Heart J. 31 (2010), 2197–2204.
7. [7] Adams, J.E., Abendschein, D.R., Jaffe, A.S., Biochemical markers of myocardial injury. Is MB creatine kinase the choice for the 1990s?. Circulation 88 (1993), 750–763.
8. [8] Apple, F.S., Simpson, P.A., Murakami, M.M., Defining the serum 99th percentile in a normal reference population measured by a high-sensitivity cardiac troponin I assay. Clin. Biochem. 43:12 (Aug 2010), 1034–1036.
9. [9] Thygesen, K., Mair, J., Jaffe, A.S., Simoons, M.L., Chaitman, B.R., White, H.D., et al. Third universal definition of myocardial infarction. Eur. Heart J. 33 (2012), 2551–2567.
10. [10] Newby, L.K., Jesse, R.L., Babb, J.D., Christenson, R.H., De Fer, T.M., Diamond, G.A., et al. ACCF 2012 expert consensus document on practical clinical considerations in the interpretation of troponin elevations: a report of the American College of Cardiology Foundation task force on Clinical Expert Consensus Documents. J. Am. Coll. Cardiol. 60 (2012), 2427–2463.
11. [11] Sato, Y., Taniguchi, R., Nagai, K., Makiyama, T., Okada, H., Yamada, T., et al. Measurements of cardiac troponin T in patients with hypertrophic cardiomyopathy. Heart 89 (2003), 659–660.
12. [12] Jaffe, A.S., Vasile, V.C., Milone, M., Saenger, A.K., Olson, K.N., Apple, F.S., Diseased skeletal muscle: a noncardiac source of increased circulating concentrations of cardiac troponin T. J. Am. Coll. Cardiol. 58 (2011), 1819–1824.
13. [13] Rittoo, D., Jones, A., Lecky, B., Neithercut, D., Elevation of cardiac troponin T, but not cardiac troponin I, in patients with neuromuscular diseases: implications for the diagnosis of myocardial infarction. J. Am. Coll. Cardiol. 63 (2014), 2411–2420.
14. [14] Valaperta, R., Sansone, V., Lombardi, F., Verdelli, C., Colombo, A., Valisi, M., et al. Identification and characterization of DM1 patients by a new diagnostic certified assay: neuromuscular and cardiac assessments. Biomed. Res. Int, 2013, 10.1155/2013/958510.
15. [15] Cardani, R., Mancinelli, E., Sansone, V., Rotondo, G., Meola, G., Biomolecular identification of (CCTG)n mutation in myotonic dystrophy type 2 (DM2) by FISH on muscle biopsy. Eur. J. Histochem. 48 (2004), 437–442.
16. [16] Giannitsis, E., Kurz, K., Hallermayer, K., Jarausch, J., Jarausch, J., Jaffe, A.S., Katus, H.A., Analytical validation of a high-sensitivity cardiac troponin T assay. Clin. Chem. 56 (2010), 254–261.
17. [17] Krintus, M., Kozinski, M., Boudry, P., Capell, N.E., Köller, U., Lackner, K., et al. European multicenter analytical evaluation of the Abbott ARCHITECT STAT high sensitive troponin I immunoassay. Clin. Chem. Lab. Med. 52 (2014), 1657–1665.
18. [18] Collinson, P.O., Gaze, D., Goodacre, S., The clinical and diagnostic performance characteristics of the high sensitivity Abbott cardiac troponin I assay. Clin. Biochem. 48 (2015), 275–281.
19. [19] Yeo, K.T., Wu, A.H., Apple, F.S., Kroll, M.H., Christenson, R.H., Lewandrowski, K.B., et al. Multicenter evaluation of the roche NT-proBNP assay and comparison to the biosite triage BNP assay. Clin. Chim. Acta 338 (2003), 107–115.
20. [20] International Federation of Clinical Chemistry (IFCC) and Laboratory Medicine, Schumann, G., Aoki, R., Ferrero, C.A., Ehlers, G., Férard, G., et al. IFCC primary reference procedures for the measurement of catalytic activity concentrations of enzymes at 37° C. Clin. Chem. Lab. Med. 44 (2006), 1146–1155.
21. [21] Lang, R.M., Bierig, M., Devereux, R.B., Flachskampf, F.A., Foster, E., Pellikka, P.A., et al. ASE committee recommendations. Recommendations for chamber quantification: a report from the American Society of Echocardiography's guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology. J. Am. Soc. Echocardiogr. 18 (2005), 1440–1463.
22. [22] Meola, G., MRI of tibialis anterior as “surrogate measure” in myotonic dystrophy type 1. Can. J. Neurol. Sci. 38:1 (Jan 2011), 10–11.
23. [23] Philips, Anne V., Timchenko, Lubov T., Cooper, Thomas A., Disruption of splicing regulated by a cug-binding protein in motonic dystrophy. Science 280 (1998), 737–741.
24. [24] Botta, A., Rinaldi, F., Catalli, C., Vergani, L., Bonifazi, E., Romeo, V., et al. The CTG repeat expansion size correlates with the splicing defects observed in muscles from myotonic dystrophy type 1 patients. J. Med. Genet. 45 (2008), 639–646.
25. [25] Yadava, R.S., Frenzel-McCardell, C.D., Yu, Q., Srinivasan, V., Tucker, A.L., Puymirat, J., Thornton, C.A., et al. RNA toxicity in myotonic muscular dystrophy induces NKX2-5 expression. Nat. Genet. 40 (2008), 61–68.
26. [26] Groh, W.J., Groh, M.R., Saha, C., et al. Electrocardiographic abnormalities and sudden death in myotonic dystrophy type 1. N. Engl. J. Med. 358 (2008), 2688–2697.
27. [27] Hickman, P.E., Potter, J.M., Aroney, C., Koerbin, G., Southcott, E., Wu, A.H., et al. Cardiac troponin may be released by ischemia alone, without necrosis. Clin. Chim. Acta 411 (2010), 318–323.
28. [28] Miao, D.M., Zhang, L.P., Yu, H.P., Zhang, J.Y., Xiao, W.K., Ye, P., Serum levels of high-sensitivity troponin T: a novel marker for left ventricular remodeling and performance in hypertensive subjects. Genet. Mol. Res. 13 (2014), 5143–5153.
29. [29] Takashio, S., Yamamuro, M., Izumiya, Y., Sugiyama, S., Kojima, S., Yamamoto, E., Coronary microvascular dysfunction and diastolic load correlate with cardiac troponin T release measured by a highly sensitive assay in patients with nonischemic heart failure. J. Am. Coll. Cardiol. 62 (2013), 632–640.