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Volumn 36, Issue 11, 2016, Pages 5867-5874

Highly halaven-resistant KBV20C cancer cells can be sensitized by co-treatment with fluphenazine

Author keywords

Drug resistance; Fluphenazine; Halaven; Mefloquine; P gp; Thioridazine

Indexed keywords

AZATHIOPRINE; ERIBULIN; FLUPHENAZINE; HISTONE H2AX; HISTONE H3; LIPOCORTIN 5; MEFLOQUINE; MULTIDRUG RESISTANCE PROTEIN; RETINOBLASTOMA PROTEIN; THIORIDAZINE; VERAPAMIL; FURAN DERIVATIVE; KETONE;

EID: 84993971937     PISSN: 02507005     EISSN: 17917530     Source Type: Journal    
DOI: 10.21873/anticanres.11172     Document Type: Article
Times cited : (25)

References (29)
  • 1
    • 1942438028 scopus 로고    scopus 로고
    • Microtubules as a target for anticancer drugs
    • Jordan MA and Wilson L: Microtubules as a target for anticancer drugs. Nat Rev Cancer 4: 253-265, 2004.
    • (2004) Nat Rev Cancer , vol.4 , pp. 253-265
    • Jordan, M.A.1    Wilson, L.2
  • 3
    • 77956625419 scopus 로고    scopus 로고
    • Prediction of chemotherapy response with platinum and taxane in the advanced stage of ovarian and uterine carcinosarcoma: A clinical implication of in vitro drug resistance assay
    • Matsuo K, Bond VK, Im DD and Rosenshein NB: Prediction of chemotherapy response with platinum and taxane in the advanced stage of ovarian and uterine carcinosarcoma: A clinical implication of in vitro drug resistance assay. Am J Clin Oncol 33: 358-363, 2010.
    • (2010) Am J Clin Oncol , vol.33 , pp. 358-363
    • Matsuo, K.1    Bond, V.K.2    Im, D.D.3    Rosenshein, N.B.4
  • 4
    • 77953533803 scopus 로고    scopus 로고
    • Targeting apoptosis pathway with natural terpenoids: Implications for treatment of breast and prostate cancer
    • Yang H and Dou QP: Targeting apoptosis pathway with natural terpenoids: Implications for treatment of breast and prostate cancer. Curr Drug Targets 11: 733-744, 2010.
    • (2010) Curr Drug Targets , vol.11 , pp. 733-744
    • Yang, H.1    Dou, Q.P.2
  • 5
    • 84943575404 scopus 로고    scopus 로고
    • Tumour biology, metastatic sites and taxanes sensitivity as determinants of eribulin mesylate efficacy in breast cancer: Results from the ERIBEX retrospective, international, multicenter study
    • Dell'Ova M, De Maio E, Guiu S, Roca L, Dalenc F, Durigova A, Pinguet F, Bekhtari K, Jacot W and Pouderoux S: Tumour biology, metastatic sites and taxanes sensitivity as determinants of eribulin mesylate efficacy in breast cancer: Results from the ERIBEX retrospective, international, multicenter study. BMC cancer 15: 659, 2015.
    • (2015) BMC Cancer , vol.15 , pp. 659
    • Dell'Ova, M.1    De Maio, E.2    Guiu, S.3    Roca, L.4    Dalenc, F.5    Durigova, A.6    Pinguet, F.7    Bekhtari, K.8    Jacot, W.9    Pouderoux, S.10
  • 8
    • 84941978785 scopus 로고    scopus 로고
    • Eribulin mesylate: Mechanism of action of a unique microtubule-targeting agent
    • Dybdal-Hargreaves NF, Risinger AL and Mooberry SL: Eribulin mesylate: mechanism of action of a unique microtubule-targeting agent. Clin Cancer Res 21: 2445-2452, 2015.
    • (2015) Clin Cancer Res , vol.21 , pp. 2445-2452
    • Dybdal-Hargreaves, N.F.1    Risinger, A.L.2    Mooberry, S.L.3
  • 10
    • 74549185974 scopus 로고    scopus 로고
    • Calmodulin inhibition contributes to sensitize TRAIL-induced apoptosis in human lung cancer H1299 cells
    • Hwang MK, Min YK and Kim SH: Calmodulin inhibition contributes to sensitize TRAIL-induced apoptosis in human lung cancer H1299 cells. Biochem Cell Biol 87: 919-926, 2009.
    • (2009) Biochem Cell Biol , vol.87 , pp. 919-926
    • Hwang, M.K.1    Min, Y.K.2    Kim, S.H.3
  • 12
    • 0031298231 scopus 로고    scopus 로고
    • Inhibitory effect of alkylating modulators on the function of P-glycoprotein
    • Yang JM, Sullivan GF, Makhey DB, LaVoie EJ and Hait WN: Inhibitory effect of alkylating modulators on the function of P-glycoprotein. Oncol Res 9: 477-484, 1997.
    • (1997) Oncol Res , vol.9 , pp. 477-484
    • Yang, J.M.1    Sullivan, G.F.2    Makhey, D.B.3    LaVoie, E.J.4    Hait, W.N.5
  • 14
    • 84983000278 scopus 로고    scopus 로고
    • Anti-malarial drugs primaquine and chloroquine have different sensitization effects with antimitotic drugs in resistant cancer cells
    • Choi AR, Kim JH, Woo YH, Kim HS and Yoon S: Anti-malarial drugs primaquine and chloroquine have different sensitization effects with antimitotic drugs in resistant cancer cells. Anticancer Res 36: 1641-1648, 2016.
    • (2016) Anticancer Res , vol.36 , pp. 1641-1648
    • Choi, A.R.1    Kim, J.H.2    Woo, Y.H.3    Kim, H.S.4    Yoon, S.5
  • 15
    • 84979711203 scopus 로고    scopus 로고
    • The synthetic ajoene analog SPA3015 induces apoptotic cell death through crosstalk between NF-kappaB and PPARgamma in multidrug-resistant cancer cells
    • Hwang JW, Cho H, Lee JY, Jeon Y, Kim SN, Lee SJ, Bae GU, Yoon S, Jeon R and Kim YK: The synthetic ajoene analog SPA3015 induces apoptotic cell death through crosstalk between NF-kappaB and PPARgamma in multidrug-resistant cancer cells. Food Chem Toxicol 96: 35-42, 2016.
    • (2016) Food Chem Toxicol , vol.96 , pp. 35-42
    • Hwang, J.W.1    Cho, H.2    Lee, J.Y.3    Jeon, Y.4    Kim, S.N.5    Lee, S.J.6    Bae, G.U.7    Yoon, S.8    Jeon, R.9    Kim, Y.K.10
  • 16
    • 84862793621 scopus 로고    scopus 로고
    • Antimitotic potential of 7-diethylamino-3(2'-benzoxazolyl)-coumarin in 5-fluorouracil-resistant human gastric cancer cell line snu620/5-fu
    • Kim NH, Kim SN, Oh JS, Lee S and Kim YK: Antimitotic potential of 7-diethylamino-3(2'-benzoxazolyl)-coumarin in 5-fluorouracil-resistant human gastric cancer cell line snu620/5-fu. Biochem Biophy Res Commun 418: 616-621, 2012.
    • (2012) Biochem Biophy Res Commun , vol.418 , pp. 616-621
    • Kim, N.H.1    Kim, S.N.2    Oh, J.S.3    Lee, S.4    Kim, Y.K.5
  • 17
    • 84935477323 scopus 로고    scopus 로고
    • Selenate specifically sensitizes drug-resistant cancer cells by increasing apoptosis via G2 phase cell cycle arrest without P-GP inhibition
    • Choi AR, Jo MJ, Jung MJ, Kim HS and Yoon S: Selenate specifically sensitizes drug-resistant cancer cells by increasing apoptosis via G2 phase cell cycle arrest without P-GP inhibition. Eur J Pharmacol 764: 63-69, 2015.
    • (2015) Eur J Pharmacol , vol.764 , pp. 63-69
    • Choi, A.R.1    Jo, M.J.2    Jung, M.J.3    Kim, H.S.4    Yoon, S.5
  • 18
    • 84939643846 scopus 로고    scopus 로고
    • Co-treatment of salinomycin sensitizes AZD5363-treated cancer cells through increased apoptosis
    • Choi AR, Jung MJ, Kim JH and Yoon S: Co-treatment of Salinomycin Sensitizes AZD5363-treated Cancer Cells Through Increased Apoptosis. Anticancer Res 35: 4741-4747, 2015.
    • (2015) Anticancer Res , vol.35 , pp. 4741-4747
    • Choi, A.R.1    Jung, M.J.2    Kim, J.H.3    Yoon, S.4
  • 19
    • 84922392505 scopus 로고    scopus 로고
    • Thioridazine specifically sensitizes drug-resistant cancer cells through highly increase in apoptosis and p-gp inhibition
    • Choi AR, Kim JH and Yoon S: Thioridazine specifically sensitizes drug-resistant cancer cells through highly increase in apoptosis and p-gp inhibition. Tumour Biol 35: 9831-9838, 2014.
    • (2014) Tumour Biol , vol.35 , pp. 9831-9838
    • Choi, A.R.1    Kim, J.H.2    Yoon, S.3
  • 20
    • 78649905860 scopus 로고    scopus 로고
    • A gene signature-based approach identifies thioridazine as an inhibitor of phosphatidylinositol-3'-kinase (PI3K)/AKT pathway in ovarian cancer cells
    • Rho SB, Kim BR and Kang S: A gene signature-based approach identifies thioridazine as an inhibitor of phosphatidylinositol-3'-kinase (PI3K)/AKT pathway in ovarian cancer cells. Gynecol Oncol 120: 121-127, 2011.
    • (2011) Gynecol Oncol , vol.120 , pp. 121-127
    • Rho, S.B.1    Kim, B.R.2    Kang, S.3
  • 21
    • 84904663784 scopus 로고    scopus 로고
    • Sensitization of cancer cells through reduction of total AKT and downregulation of salinomycin-induction of pAKT, pGSK3beta, pTSC2, and p4EBP1 by cotreatment with MK-2206
    • Choi AR, Kim JH and Yoon S: Sensitization of cancer cells through reduction of total AKT and downregulation of salinomycin-induction of pAKT, pGSK3beta, pTSC2, and p4EBP1 by cotreatment with MK-2206. Biomed Res Int 2014: 295760, 2014.
    • (2014) Biomed Res Int , vol.2014
    • Choi, A.R.1    Kim, J.H.2    Yoon, S.3
  • 22
    • 84883472741 scopus 로고    scopus 로고
    • Low amount of salinomycin greatly increases AKT activation, but reduces activated p70S6K levels
    • Kim JH, Choi AR, Kim YK, Kim HS and Yoon S: Low amount of salinomycin Greatly increases AKT activation, but reduces activated p70S6K levels. Int J Mol Sci 14: 17304-17318, 2013.
    • (2013) Int J Mol Sci , vol.14 , pp. 17304-17318
    • Kim, J.H.1    Choi, A.R.2    Kim, Y.K.3    Kim, H.S.4    Yoon, S.5
  • 23
    • 84888302578 scopus 로고    scopus 로고
    • Co-treatment with the anti-malarial drugs mefloquine and primaquine highly sensitizes drug-resistant cancer cells by increasing P-gp inhibition
    • Kim JH, Choi AR, Kim YK and Yoon S: Co-treatment with the anti-malarial drugs mefloquine and primaquine highly sensitizes drug-resistant cancer cells by increasing P-gp inhibition. Biochem Biophys Res Commun 441: 655-660, 2013.
    • (2013) Biochem Biophys Res Commun , vol.441 , pp. 655-660
    • Kim, J.H.1    Choi, A.R.2    Kim, Y.K.3    Yoon, S.4
  • 25
    • 84891350375 scopus 로고    scopus 로고
    • SP600125 overcomes antimitotic drug-resistance in cancer cells by increasing apoptosis with independence of P-gp inhibition
    • Kim JH, Chae M, Choi AR, Sik Kim H and Yoon S: SP600125 overcomes antimitotic drug-resistance in cancer cells by increasing apoptosis with independence of P-gp inhibition. Eur J Pharmacol 723: 141-147, 2014.
    • (2014) Eur J Pharmacol , vol.723 , pp. 141-147
    • Kim, J.H.1    Chae, M.2    Choi, A.R.3    Sik Kim, H.4    Yoon, S.5
  • 26
    • 84887953273 scopus 로고    scopus 로고
    • New therapeutic bearings for repositioned drugs
    • Clark KB: New therapeutic bearings for repositioned drugs. Curr Top Med Chem 13: 2281-2282, 2013.
    • (2013) Curr Top Med Chem , vol.13 , pp. 2281-2282
    • Clark, K.B.1
  • 27
    • 84994019959 scopus 로고    scopus 로고
    • Recycling existing drugs for cancer therapy: Delivering low cost cancer care
    • Pantziarka P and Cairns L: Recycling existing drugs for cancer therapy: delivering low cost cancer care. Ecancermedicalscience 8: ed40, 2014.
    • (2014) Ecancermedicalscience , vol.8 , pp. ed40
    • Pantziarka, P.1    Cairns, L.2
  • 28
    • 84898071578 scopus 로고    scopus 로고
    • Phase separation in phosphatidylcholine membrane caused by the presence of a pyrimidine analogue of fluphenazine with high anti-multidrug-resistance activity
    • Cieslik-Boczula K, Swiatek P, Jaszczyszyn A, Zawilska P, Gasiorowski K, Malinka W and Kohler G: Phase separation in phosphatidylcholine membrane caused by the presence of a pyrimidine analogue of fluphenazine with high anti-multidrug-resistance activity. J Phys Chem B 118: 3605-3615, 2014.
    • (2014) J Phys Chem B , vol.118 , pp. 3605-3615
    • Cieslik-Boczula, K.1    Swiatek, P.2    Jaszczyszyn, A.3    Zawilska, P.4    Gasiorowski, K.5    Malinka, W.6    Kohler, G.7
  • 29
    • 84888073521 scopus 로고    scopus 로고
    • Potential antitumor mechanisms of phenothiazine drugs
    • Qi L and Ding Y: Potential antitumor mechanisms of phenothiazine drugs. Sci China Life Sci 56: 1020-1027, 2013.
    • (2013) Sci China Life Sci , vol.56 , pp. 1020-1027
    • Qi, L.1    Ding, Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.