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Volumn 87, Issue 6, 2009, Pages 919-926

Calmodulin inhibition contributes to sensitize TRAIL-induced apoptosis in human lung cancer H1299 cells

Author keywords

Apoptosis; Calmodulin antagonists; Fluphenazine N 2 chloroethane; Tumor necrosis factor related apoptosis inducing ligand

Indexed keywords

AKT PHOSPHORYLATION; APOPTOSIS; APOPTOTIC; CASPASES; CONVERTING ENZYME; DEATH-INDUCING SIGNALING COMPLEXES; ENZYME INHIBITORS; FAS-ASSOCIATED DEATH DOMAINS; FLUPHENAZINE-N-2-CHLOROETHANE; HUMAN LUNG; IN-CELL; INDUCED APOPTOSIS; INHIBITOR OF APOPTOSIS PROTEINS; INHIBITORY PROTEINS; INTERLEUKIN-1; LUNG CANCER; LUNG CANCER CELLS; THERAPEUTIC POTENTIALS; TUMOR CELLS; TUMOR NECROSIS FACTORS;

EID: 74549185974     PISSN: 08298211     EISSN: 12086002     Source Type: Journal    
DOI: 10.1139/O09-058     Document Type: Article
Times cited : (14)

References (28)
  • 1
    • 0036598992 scopus 로고    scopus 로고
    • Targeting death and decoy receptors of the tumour-necrosis factor superfamily
    • PMID:12189384, doi:10.1038/nrc821
    • Ashkenazi, A. 2002. Targeting death and decoy receptors of the tumour-necrosis factor superfamily. Nat. Rev. Cancer, 2(6): 420-430. doi:10.1038/nrc821. PMID:12189384.
    • (2002) Nat. Rev. Cancer , vol.2 , Issue.6 , pp. 420-430
    • Ashkenazi, A.1
  • 2
    • 34250013331 scopus 로고    scopus 로고
    • Impaired apoptosis in lymphoblasts from Alzheimer's disease patients: Cross-talk of Ca2+/calmodulin and ERK1/2 signaling pathways
    • PMID:17502994, doi:10.1007/s00018- 007-7081-3
    • Bartolomé, F., de Las Cuevas, N., Muñoz, U., Bermejo, F., and Martín-Requero, A. 2007. Impaired apoptosis in lymphoblasts from Alzheimer's disease patients: cross-talk of Ca2+/calmodulin and ERK1/2 signaling pathways. Cell. Mol. Life Sci. 64(11): 1437-1448. doi:10.1007/s00018- 007-7081-3. PMID:17502994.
    • (2007) Cell. Mol. Life Sci , vol.64 , Issue.11 , pp. 1437-1448
    • Bartolomé, F.1    de Las Cuevas, N.2    Muñoz, U.3    Bermejo, F.4    Martín-Requero, A.5
  • 3
    • 4344660599 scopus 로고    scopus 로고
    • Downregulation of Bcl-2, FLIP or IAPs (XIAP and survivin) by siRNAs sensitizes resistant melanoma cells to Apo2L/TRAIL-induced apoptosis
    • PMID:15118763, doi:10.1038/sj.cdd.4401416
    • Chawla-Sarkar, M., Bae, S.I., Reu, F.J., Jacobs, B.S., Lindner, D.J., and Borden, E.C. 2004. Downregulation of Bcl-2, FLIP or IAPs (XIAP and survivin) by siRNAs sensitizes resistant melanoma cells to Apo2L/TRAIL-induced apoptosis. Cell Death Differ. 11(8): 915-923. doi:10.1038/sj.cdd.4401416. PMID:15118763.
    • (2004) Cell Death Differ , vol.11 , Issue.8 , pp. 915-923
    • Chawla-Sarkar, M.1    Bae, S.I.2    Reu, F.J.3    Jacobs, B.S.4    Lindner, D.J.5    Borden, E.C.6
  • 4
    • 39049145895 scopus 로고    scopus 로고
    • Calmodulin binding to the Fas-mediated death-inducing signaling complex in cholangiocarcinoma cells
    • PMID: 17654480, doi:10.1002/jcb.21447
    • Chen, Y., Pawar, P., Pan, G., Ma, L., Liu, H., and McDonald, J.M. 2008. Calmodulin binding to the Fas-mediated death-inducing signaling complex in cholangiocarcinoma cells. J. Cell. Biochem. 103(3): 788-799. doi:10.1002/jcb.21447. PMID: 17654480.
    • (2008) J. Cell. Biochem , vol.103 , Issue.3 , pp. 788-799
    • Chen, Y.1    Pawar, P.2    Pan, G.3    Ma, L.4    Liu, H.5    McDonald, J.M.6
  • 5
    • 0018872612 scopus 로고
    • Calmodulin plays a pivotal role in cellular regulation
    • PMID:6243188, doi:10.1126/science. 6243188
    • Cheung, W.Y. 1980. Calmodulin plays a pivotal role in cellular regulation. Science, 207(4426): 19-27. doi:10.1126/science. 6243188. PMID:6243188.
    • (1980) Science , vol.207 , Issue.4426 , pp. 19-27
    • Cheung, W.Y.1
  • 6
    • 0030931876 scopus 로고    scopus 로고
    • Caspases: The executioners of apoptosis
    • PMID:9337844
    • Cohen, G.M. 1997. Caspases: the executioners of apoptosis. Biochem. J. 326(Pt 1): 1-16. PMID:9337844.
    • (1997) Biochem. J , vol.326 , Issue.PART 1 , pp. 1-16
    • Cohen, G.M.1
  • 7
    • 67349100507 scopus 로고    scopus 로고
    • Calmodulin modulates Akt activity in human breast cancer cell lines
    • PMID:18587642, doi:10.1007/s10549-008-0097-z
    • Coticchia, C.M., Revankar, C.M., Deb, T.B., Dickson, R.B., and Johnson, M.D. 2009. Calmodulin modulates Akt activity in human breast cancer cell lines. Breast Cancer Res. Treat. 115(3): 545-560. doi:10.1007/s10549-008-0097-z. PMID:18587642.
    • (2009) Breast Cancer Res. Treat , vol.115 , Issue.3 , pp. 545-560
    • Coticchia, C.M.1    Revankar, C.M.2    Deb, T.B.3    Dickson, R.B.4    Johnson, M.D.5
  • 8
    • 0034630186 scopus 로고    scopus 로고
    • Serine/threonine protein kinases and apoptosis
    • PMID:10739649, doi:10.1006/excr. 2000.4836
    • Cross, T.G., Scheel-Toellner, D., Henriquez, N.V., Deacon, E., Salmon, M., and Lord, J.M. 2000. Serine/threonine protein kinases and apoptosis. Exp. Cell Res. 256(1): 34-41. doi:10.1006/excr. 2000.4836. PMID:10739649.
    • (2000) Exp. Cell Res , vol.256 , Issue.1 , pp. 34-41
    • Cross, T.G.1    Scheel-Toellner, D.2    Henriquez, N.V.3    Deacon, E.4    Salmon, M.5    Lord, J.M.6
  • 9
    • 4644303140 scopus 로고    scopus 로고
    • Calmodulinmediated activation of Akt regulates survival of c-Myc-overexpressing mouse mammary carcinoma cells
    • PMID: 15247222, doi:10.1074/jbc.M405314200
    • Deb, T.B., Coticchia, C.M., and Dickson, R.B. 2004. Calmodulinmediated activation of Akt regulates survival of c-Myc-overexpressing mouse mammary carcinoma cells. J. Biol. Chem. 279(37): 38903-38911. doi:10.1074/jbc.M405314200. PMID: 15247222.
    • (2004) J. Biol. Chem , vol.279 , Issue.37 , pp. 38903-38911
    • Deb, T.B.1    Coticchia, C.M.2    Dickson, R.B.3
  • 10
    • 0022516721 scopus 로고
    • Calmodulin: A potential target for cancer chemotherapeutic agents
    • PMID:2423656
    • Hait, W.N., and Lazo, J.S. 1986. Calmodulin: a potential target for cancer chemotherapeutic agents. J. Clin. Oncol. 4(6): 994-1012. PMID:2423656.
    • (1986) J. Clin. Oncol , vol.4 , Issue.6 , pp. 994-1012
    • Hait, W.N.1    Lazo, J.S.2
  • 11
    • 0023518534 scopus 로고
    • Pharmacological properties of fluphenazine-mustard, an irreversible calmodulin antagonist
    • PMID:3670276
    • Hait, W.N., Glazer, L., Kaiser, C., Cross, J., and Kennedy, K.A. 1987. Pharmacological properties of fluphenazine-mustard, an irreversible calmodulin antagonist. Mol. Pharmacol. 32(3): 404-409. PMID:3670276.
    • (1987) Mol. Pharmacol , vol.32 , Issue.3 , pp. 404-409
    • Hait, W.N.1    Glazer, L.2    Kaiser, C.3    Cross, J.4    Kennedy, K.A.5
  • 12
    • 33646112384 scopus 로고    scopus 로고
    • Proteasome inhibition sensitizes hepatocellular carcinoma cells to TRAIL by suppressing caspase inhibitors and AKT pathway
    • PMID:16520654, doi:10.1097/00001813-200603000-00004
    • Inoue, T., Shiraki, K., Fuke, H., Yamanaka, Y., Miyashita, K., Yamaguchi, Y., et al. 2006. Proteasome inhibition sensitizes hepatocellular carcinoma cells to TRAIL by suppressing caspase inhibitors and AKT pathway. Anticancer Drugs, 17(3): 261-268. doi:10.1097/00001813-200603000-00004. PMID:16520654.
    • (2006) Anticancer Drugs , vol.17 , Issue.3 , pp. 261-268
    • Inoue, T.1    Shiraki, K.2    Fuke, H.3    Yamanaka, Y.4    Miyashita, K.5    Yamaguchi, Y.6
  • 13
    • 0030800070 scopus 로고    scopus 로고
    • Inhibition of death receptor signals by cellular FLIP
    • PMID:9217161, doi:10.1038/40657
    • Irmler, M., Thome, M., Hahne, M., Schneider, P., Hofmann, K., Steiner, V., et al. 1997. Inhibition of death receptor signals by cellular FLIP. Nature, 388(6638): 190-195. doi:10.1038/40657. PMID:9217161.
    • (1997) Nature , vol.388 , Issue.6638 , pp. 190-195
    • Irmler, M.1    Thome, M.2    Hahne, M.3    Schneider, P.4    Hofmann, K.5    Steiner, V.6
  • 14
    • 0025865899 scopus 로고
    • Inhibition of lung metastasis by a calmodulin antagonist, N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7), in mice bearing Lewis lung carcinoma
    • PMID: 2018358
    • Ito, H., Wang, J.Z., and Shimura, K. 1991. Inhibition of lung metastasis by a calmodulin antagonist, N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7), in mice bearing Lewis lung carcinoma. Anticancer Res. 11(1): 249-252. PMID: 2018358.
    • (1991) Anticancer Res , vol.11 , Issue.1 , pp. 249-252
    • Ito, H.1    Wang, J.Z.2    Shimura, K.3
  • 15
    • 34447097884 scopus 로고    scopus 로고
    • Sulforaphane sensitizes tumor necrosis factorrelated apoptosis-inducing ligand-mediated apoptosis through downregulation of ERK and Akt in lung adenocarcinoma A549 cells
    • PMID:17183064, doi:10.1093/carcin/bgl251
    • Jin, C.Y., Moon, D.O., Lee, J.D., Heo, M.S., Choi, Y.H., Lee, C.M., et al. 2007. Sulforaphane sensitizes tumor necrosis factorrelated apoptosis-inducing ligand-mediated apoptosis through downregulation of ERK and Akt in lung adenocarcinoma A549 cells. Carcinogenesis, 28(5): 1058-1066. doi:10.1093/carcin/bgl251. PMID:17183064.
    • (2007) Carcinogenesis , vol.28 , Issue.5 , pp. 1058-1066
    • Jin, C.Y.1    Moon, D.O.2    Lee, J.D.3    Heo, M.S.4    Choi, Y.H.5    Lee, C.M.6
  • 16
    • 0037273848 scopus 로고    scopus 로고
    • Apo2L/TRAIL and its death and decoy receptors
    • PMID:12655296, doi:10.1038/sj.cdd. 4401187
    • LeBlanc, H.N., and Ashkenazi, A. 2003. Apo2L/TRAIL and its death and decoy receptors. Cell Death Differ. 10(1): 66-75. doi:10.1038/sj.cdd. 4401187. PMID:12655296.
    • (2003) Cell Death Differ , vol.10 , Issue.1 , pp. 66-75
    • LeBlanc, H.N.1    Ashkenazi, A.2
  • 17
    • 26444557730 scopus 로고    scopus 로고
    • a5b1 integrin stimulates Bcl-2 expression and cell survival through Akt, focal adhesion kinase, and Ca2+/calmodulin-dependent protein kinase IV
    • PMID:15962308, doi:10.1002/jcb.20488
    • Lee, B.H., and Ruoslahti, E. 2005. a5b1 integrin stimulates Bcl-2 expression and cell survival through Akt, focal adhesion kinase, and Ca2+/calmodulin-dependent protein kinase IV. J. Cell. Biochem. 95(6): 1214-1223. doi:10.1002/jcb.20488. PMID:15962308.
    • (2005) J. Cell. Biochem , vol.95 , Issue.6 , pp. 1214-1223
    • Lee, B.H.1    Ruoslahti, E.2
  • 18
    • 33947502315 scopus 로고    scopus 로고
    • hPEBP4 resists TRAIL-induced apoptosis of human prostate cancer cells by activating Akt and deactivating ERK1/2 pathways
    • PMID:17178731, doi:10.1074/jbc.M609494200
    • Li, H., Wang, X., Li, N., Qiu, J., Zhang, Y., and Cao, X. 2007. hPEBP4 resists TRAIL-induced apoptosis of human prostate cancer cells by activating Akt and deactivating ERK1/2 pathways. J. Biol. Chem. 282(7): 4943-4950. doi:10.1074/jbc.M609494200. PMID:17178731.
    • (2007) J. Biol. Chem , vol.282 , Issue.7 , pp. 4943-4950
    • Li, H.1    Wang, X.2    Li, N.3    Qiu, J.4    Zhang, Y.5    Cao, X.6
  • 19
    • 0035831556 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase/Akt activity regulates c-FLIP expression in tumor cells
    • PMID:11145953, doi:10.1074/jbc.C000569200
    • Panka, D.J., Mano, T., Suhara, T., Walsh, K., and Mier, J.W. 2001. Phosphatidylinositol 3-kinase/Akt activity regulates c-FLIP expression in tumor cells. J. Biol. Chem. 276(10): 6893-6896. doi:10.1074/jbc.C000569200. PMID:11145953.
    • (2001) J. Biol. Chem , vol.276 , Issue.10 , pp. 6893-6896
    • Panka, D.J.1    Mano, T.2    Suhara, T.3    Walsh, K.4    Mier, J.W.5
  • 20
    • 45349102347 scopus 로고    scopus 로고
    • Calmodulin binding to cellular FLICE-like inhibitory protein modulates Fas-induced signalling
    • PMID:18257744, doi:10.1042/BJ20071507
    • Pawar, P.S., Micoli, K.J., Ding, H., Cook, W.J., Kappes, J.C., Chen, Y., and McDonald, J.M. 2008. Calmodulin binding to cellular FLICE-like inhibitory protein modulates Fas-induced signalling. Biochem. J. 412(3): 459-468. doi:10.1042/BJ20071507. PMID:18257744.
    • (2008) Biochem. J , vol.412 , Issue.3 , pp. 459-468
    • Pawar, P.S.1    Micoli, K.J.2    Ding, H.3    Cook, W.J.4    Kappes, J.C.5    Chen, Y.6    McDonald, J.M.7
  • 21
    • 0033584823 scopus 로고    scopus 로고
    • Locoregional Apo2L/TRAIL eradicates intracranial human malignant glioma xenografts in athymic mice in the absence of neurotoxicity
    • PMID:10558893, doi:10.1006/bbrc.1999.1693
    • Roth, W., Isenmann, S., Naumann, U., Kügler, S., Bähr, M., Dichgans, J., et al. 1999. Locoregional Apo2L/TRAIL eradicates intracranial human malignant glioma xenografts in athymic mice in the absence of neurotoxicity. Biochem. Biophys. Res. Commun. 265(2): 479-483. doi:10.1006/bbrc.1999.1693. PMID:10558893.
    • (1999) Biochem. Biophys. Res. Commun , vol.265 , Issue.2 , pp. 479-483
    • Roth, W.1    Isenmann, S.2    Naumann, U.3    Kügler, S.4    Bähr, M.5    Dichgans, J.6
  • 22
    • 5644259587 scopus 로고    scopus 로고
    • Inhibitor of apoptosis proteins: Translating basic knowledge into clinical practice
    • PMID:15492230, doi:10.1158/0008-5472.CAN-04-1918
    • Schimmer, A.D. 2004. Inhibitor of apoptosis proteins: translating basic knowledge into clinical practice. Cancer Res. 64(20): 7183-7190. doi:10.1158/0008-5472.CAN-04-1918. PMID:15492230.
    • (2004) Cancer Res , vol.64 , Issue.20 , pp. 7183-7190
    • Schimmer, A.D.1
  • 23
    • 22644436371 scopus 로고    scopus 로고
    • Wortmannin elevates tumor necrosis factor-related apoptosis-inducing ligand sensitivity in LNCaP cells through down-regulation of IAP-2 protein
    • PMID:15995629
    • Seol, J.W., Lee, Y.J., Kang, H.S., Kim, I.S., Kim, N.S., Kwak, Y.G., et al. 2005. Wortmannin elevates tumor necrosis factor-related apoptosis-inducing ligand sensitivity in LNCaP cells through down-regulation of IAP-2 protein. Exp. Oncol. 27(2): 120-124. PMID:15995629.
    • (2005) Exp. Oncol , vol.27 , Issue.2 , pp. 120-124
    • Seol, J.W.1    Lee, Y.J.2    Kang, H.S.3    Kim, I.S.4    Kim, N.S.5    Kwak, Y.G.6
  • 24
    • 56449084185 scopus 로고    scopus 로고
    • Synergistic proapoptotic activity of recombinant TRAIL plus the Akt inhibitor Perifosine in acute myelogenous leukemia cells
    • PMID:19010914, doi:10.1158/0008-5472.CAN-08-2815
    • Tazzari, P.L., Tabellini, G., Ricci, F., Papa, V., Bortul, R., Chiarini, F., et al. 2008. Synergistic proapoptotic activity of recombinant TRAIL plus the Akt inhibitor Perifosine in acute myelogenous leukemia cells. Cancer Res. 68(22): 9394-9403. doi:10.1158/0008-5472.CAN-08-2815. PMID:19010914.
    • (2008) Cancer Res , vol.68 , Issue.22 , pp. 9394-9403
    • Tazzari, P.L.1    Tabellini, G.2    Ricci, F.3    Papa, V.4    Bortul, R.5    Chiarini, F.6
  • 25
    • 0023280606 scopus 로고
    • Comparison of the effects of fluphenazine-N-mustard on dopamine binding sites and on behavior induced by apomorphine in supersensitive mice
    • PMID:3120028, doi:10.1016/0028-3908(87)90166-3
    • Thermos, K., Winkler, J.D., and Weiss, B. 1987. Comparison of the effects of fluphenazine-N-mustard on dopamine binding sites and on behavior induced by apomorphine in supersensitive mice. Neuropharmacology, 26(10): 1473-1480. doi:10.1016/0028-3908(87)90166-3. PMID:3120028.
    • (1987) Neuropharmacology , vol.26 , Issue.10 , pp. 1473-1480
    • Thermos, K.1    Winkler, J.D.2    Weiss, B.3
  • 26
    • 0020950993 scopus 로고
    • Calcium and calmodulin in cell growth and transformation
    • PMID:6331500
    • Veigl, M.L., Vanaman, T.C., and Sedwick, W.D. 1984. Calcium and calmodulin in cell growth and transformation. Biochim. Biophys. Acta, 738(1-2): 21-48. PMID:6331500.
    • (1984) Biochim. Biophys. Acta , vol.738 , Issue.1-2 , pp. 21-48
    • Veigl, M.L.1    Vanaman, T.C.2    Sedwick, W.D.3
  • 27
    • 54249159248 scopus 로고    scopus 로고
    • Targeting XIAP bypasses Bcl-2-mediated resistance to TRAIL and cooperates with TRAIL to suppress pancreatic cancer growth in vitro and in vivo
    • PMID:18829553, doi:10.1158/0008-5472.CAN-08-1296
    • Vogler, M., Walczak, H., Stadel, D., Haas, T.L., Genze, F., Jovanovic, M., et al. 2008. Targeting XIAP bypasses Bcl-2-mediated resistance to TRAIL and cooperates with TRAIL to suppress pancreatic cancer growth in vitro and in vivo. Cancer Res. 68(19): 7956-7965. doi:10.1158/0008-5472.CAN-08-1296. PMID:18829553.
    • (2008) Cancer Res , vol.68 , Issue.19 , pp. 7956-7965
    • Vogler, M.1    Walczak, H.2    Stadel, D.3    Haas, T.L.4    Genze, F.5    Jovanovic, M.6
  • 28
    • 0032929520 scopus 로고    scopus 로고
    • Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo
    • PMID:9930862, doi:10.1038/5517
    • Walczak, H., Miller, R.E., Ariail, K., Gliniak, B., Griffith, T.S., Kubin, M., et al. 1999. Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo. Nat. Med. 5(2): 157-163. doi:10.1038/5517. PMID:9930862.
    • (1999) Nat. Med , vol.5 , Issue.2 , pp. 157-163
    • Walczak, H.1    Miller, R.E.2    Ariail, K.3    Gliniak, B.4    Griffith, T.S.5    Kubin, M.6


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