-
1
-
-
0036598992
-
Targeting death and decoy receptors of the tumour-necrosis factor superfamily
-
PMID:12189384, doi:10.1038/nrc821
-
Ashkenazi, A. 2002. Targeting death and decoy receptors of the tumour-necrosis factor superfamily. Nat. Rev. Cancer, 2(6): 420-430. doi:10.1038/nrc821. PMID:12189384.
-
(2002)
Nat. Rev. Cancer
, vol.2
, Issue.6
, pp. 420-430
-
-
Ashkenazi, A.1
-
2
-
-
34250013331
-
Impaired apoptosis in lymphoblasts from Alzheimer's disease patients: Cross-talk of Ca2+/calmodulin and ERK1/2 signaling pathways
-
PMID:17502994, doi:10.1007/s00018- 007-7081-3
-
Bartolomé, F., de Las Cuevas, N., Muñoz, U., Bermejo, F., and Martín-Requero, A. 2007. Impaired apoptosis in lymphoblasts from Alzheimer's disease patients: cross-talk of Ca2+/calmodulin and ERK1/2 signaling pathways. Cell. Mol. Life Sci. 64(11): 1437-1448. doi:10.1007/s00018- 007-7081-3. PMID:17502994.
-
(2007)
Cell. Mol. Life Sci
, vol.64
, Issue.11
, pp. 1437-1448
-
-
Bartolomé, F.1
de Las Cuevas, N.2
Muñoz, U.3
Bermejo, F.4
Martín-Requero, A.5
-
3
-
-
4344660599
-
Downregulation of Bcl-2, FLIP or IAPs (XIAP and survivin) by siRNAs sensitizes resistant melanoma cells to Apo2L/TRAIL-induced apoptosis
-
PMID:15118763, doi:10.1038/sj.cdd.4401416
-
Chawla-Sarkar, M., Bae, S.I., Reu, F.J., Jacobs, B.S., Lindner, D.J., and Borden, E.C. 2004. Downregulation of Bcl-2, FLIP or IAPs (XIAP and survivin) by siRNAs sensitizes resistant melanoma cells to Apo2L/TRAIL-induced apoptosis. Cell Death Differ. 11(8): 915-923. doi:10.1038/sj.cdd.4401416. PMID:15118763.
-
(2004)
Cell Death Differ
, vol.11
, Issue.8
, pp. 915-923
-
-
Chawla-Sarkar, M.1
Bae, S.I.2
Reu, F.J.3
Jacobs, B.S.4
Lindner, D.J.5
Borden, E.C.6
-
4
-
-
39049145895
-
Calmodulin binding to the Fas-mediated death-inducing signaling complex in cholangiocarcinoma cells
-
PMID: 17654480, doi:10.1002/jcb.21447
-
Chen, Y., Pawar, P., Pan, G., Ma, L., Liu, H., and McDonald, J.M. 2008. Calmodulin binding to the Fas-mediated death-inducing signaling complex in cholangiocarcinoma cells. J. Cell. Biochem. 103(3): 788-799. doi:10.1002/jcb.21447. PMID: 17654480.
-
(2008)
J. Cell. Biochem
, vol.103
, Issue.3
, pp. 788-799
-
-
Chen, Y.1
Pawar, P.2
Pan, G.3
Ma, L.4
Liu, H.5
McDonald, J.M.6
-
5
-
-
0018872612
-
Calmodulin plays a pivotal role in cellular regulation
-
PMID:6243188, doi:10.1126/science. 6243188
-
Cheung, W.Y. 1980. Calmodulin plays a pivotal role in cellular regulation. Science, 207(4426): 19-27. doi:10.1126/science. 6243188. PMID:6243188.
-
(1980)
Science
, vol.207
, Issue.4426
, pp. 19-27
-
-
Cheung, W.Y.1
-
6
-
-
0030931876
-
Caspases: The executioners of apoptosis
-
PMID:9337844
-
Cohen, G.M. 1997. Caspases: the executioners of apoptosis. Biochem. J. 326(Pt 1): 1-16. PMID:9337844.
-
(1997)
Biochem. J
, vol.326
, Issue.PART 1
, pp. 1-16
-
-
Cohen, G.M.1
-
7
-
-
67349100507
-
Calmodulin modulates Akt activity in human breast cancer cell lines
-
PMID:18587642, doi:10.1007/s10549-008-0097-z
-
Coticchia, C.M., Revankar, C.M., Deb, T.B., Dickson, R.B., and Johnson, M.D. 2009. Calmodulin modulates Akt activity in human breast cancer cell lines. Breast Cancer Res. Treat. 115(3): 545-560. doi:10.1007/s10549-008-0097-z. PMID:18587642.
-
(2009)
Breast Cancer Res. Treat
, vol.115
, Issue.3
, pp. 545-560
-
-
Coticchia, C.M.1
Revankar, C.M.2
Deb, T.B.3
Dickson, R.B.4
Johnson, M.D.5
-
8
-
-
0034630186
-
Serine/threonine protein kinases and apoptosis
-
PMID:10739649, doi:10.1006/excr. 2000.4836
-
Cross, T.G., Scheel-Toellner, D., Henriquez, N.V., Deacon, E., Salmon, M., and Lord, J.M. 2000. Serine/threonine protein kinases and apoptosis. Exp. Cell Res. 256(1): 34-41. doi:10.1006/excr. 2000.4836. PMID:10739649.
-
(2000)
Exp. Cell Res
, vol.256
, Issue.1
, pp. 34-41
-
-
Cross, T.G.1
Scheel-Toellner, D.2
Henriquez, N.V.3
Deacon, E.4
Salmon, M.5
Lord, J.M.6
-
9
-
-
4644303140
-
Calmodulinmediated activation of Akt regulates survival of c-Myc-overexpressing mouse mammary carcinoma cells
-
PMID: 15247222, doi:10.1074/jbc.M405314200
-
Deb, T.B., Coticchia, C.M., and Dickson, R.B. 2004. Calmodulinmediated activation of Akt regulates survival of c-Myc-overexpressing mouse mammary carcinoma cells. J. Biol. Chem. 279(37): 38903-38911. doi:10.1074/jbc.M405314200. PMID: 15247222.
-
(2004)
J. Biol. Chem
, vol.279
, Issue.37
, pp. 38903-38911
-
-
Deb, T.B.1
Coticchia, C.M.2
Dickson, R.B.3
-
10
-
-
0022516721
-
Calmodulin: A potential target for cancer chemotherapeutic agents
-
PMID:2423656
-
Hait, W.N., and Lazo, J.S. 1986. Calmodulin: a potential target for cancer chemotherapeutic agents. J. Clin. Oncol. 4(6): 994-1012. PMID:2423656.
-
(1986)
J. Clin. Oncol
, vol.4
, Issue.6
, pp. 994-1012
-
-
Hait, W.N.1
Lazo, J.S.2
-
11
-
-
0023518534
-
Pharmacological properties of fluphenazine-mustard, an irreversible calmodulin antagonist
-
PMID:3670276
-
Hait, W.N., Glazer, L., Kaiser, C., Cross, J., and Kennedy, K.A. 1987. Pharmacological properties of fluphenazine-mustard, an irreversible calmodulin antagonist. Mol. Pharmacol. 32(3): 404-409. PMID:3670276.
-
(1987)
Mol. Pharmacol
, vol.32
, Issue.3
, pp. 404-409
-
-
Hait, W.N.1
Glazer, L.2
Kaiser, C.3
Cross, J.4
Kennedy, K.A.5
-
12
-
-
33646112384
-
Proteasome inhibition sensitizes hepatocellular carcinoma cells to TRAIL by suppressing caspase inhibitors and AKT pathway
-
PMID:16520654, doi:10.1097/00001813-200603000-00004
-
Inoue, T., Shiraki, K., Fuke, H., Yamanaka, Y., Miyashita, K., Yamaguchi, Y., et al. 2006. Proteasome inhibition sensitizes hepatocellular carcinoma cells to TRAIL by suppressing caspase inhibitors and AKT pathway. Anticancer Drugs, 17(3): 261-268. doi:10.1097/00001813-200603000-00004. PMID:16520654.
-
(2006)
Anticancer Drugs
, vol.17
, Issue.3
, pp. 261-268
-
-
Inoue, T.1
Shiraki, K.2
Fuke, H.3
Yamanaka, Y.4
Miyashita, K.5
Yamaguchi, Y.6
-
13
-
-
0030800070
-
Inhibition of death receptor signals by cellular FLIP
-
PMID:9217161, doi:10.1038/40657
-
Irmler, M., Thome, M., Hahne, M., Schneider, P., Hofmann, K., Steiner, V., et al. 1997. Inhibition of death receptor signals by cellular FLIP. Nature, 388(6638): 190-195. doi:10.1038/40657. PMID:9217161.
-
(1997)
Nature
, vol.388
, Issue.6638
, pp. 190-195
-
-
Irmler, M.1
Thome, M.2
Hahne, M.3
Schneider, P.4
Hofmann, K.5
Steiner, V.6
-
14
-
-
0025865899
-
Inhibition of lung metastasis by a calmodulin antagonist, N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7), in mice bearing Lewis lung carcinoma
-
PMID: 2018358
-
Ito, H., Wang, J.Z., and Shimura, K. 1991. Inhibition of lung metastasis by a calmodulin antagonist, N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7), in mice bearing Lewis lung carcinoma. Anticancer Res. 11(1): 249-252. PMID: 2018358.
-
(1991)
Anticancer Res
, vol.11
, Issue.1
, pp. 249-252
-
-
Ito, H.1
Wang, J.Z.2
Shimura, K.3
-
15
-
-
34447097884
-
Sulforaphane sensitizes tumor necrosis factorrelated apoptosis-inducing ligand-mediated apoptosis through downregulation of ERK and Akt in lung adenocarcinoma A549 cells
-
PMID:17183064, doi:10.1093/carcin/bgl251
-
Jin, C.Y., Moon, D.O., Lee, J.D., Heo, M.S., Choi, Y.H., Lee, C.M., et al. 2007. Sulforaphane sensitizes tumor necrosis factorrelated apoptosis-inducing ligand-mediated apoptosis through downregulation of ERK and Akt in lung adenocarcinoma A549 cells. Carcinogenesis, 28(5): 1058-1066. doi:10.1093/carcin/bgl251. PMID:17183064.
-
(2007)
Carcinogenesis
, vol.28
, Issue.5
, pp. 1058-1066
-
-
Jin, C.Y.1
Moon, D.O.2
Lee, J.D.3
Heo, M.S.4
Choi, Y.H.5
Lee, C.M.6
-
16
-
-
0037273848
-
Apo2L/TRAIL and its death and decoy receptors
-
PMID:12655296, doi:10.1038/sj.cdd. 4401187
-
LeBlanc, H.N., and Ashkenazi, A. 2003. Apo2L/TRAIL and its death and decoy receptors. Cell Death Differ. 10(1): 66-75. doi:10.1038/sj.cdd. 4401187. PMID:12655296.
-
(2003)
Cell Death Differ
, vol.10
, Issue.1
, pp. 66-75
-
-
LeBlanc, H.N.1
Ashkenazi, A.2
-
17
-
-
26444557730
-
a5b1 integrin stimulates Bcl-2 expression and cell survival through Akt, focal adhesion kinase, and Ca2+/calmodulin-dependent protein kinase IV
-
PMID:15962308, doi:10.1002/jcb.20488
-
Lee, B.H., and Ruoslahti, E. 2005. a5b1 integrin stimulates Bcl-2 expression and cell survival through Akt, focal adhesion kinase, and Ca2+/calmodulin-dependent protein kinase IV. J. Cell. Biochem. 95(6): 1214-1223. doi:10.1002/jcb.20488. PMID:15962308.
-
(2005)
J. Cell. Biochem
, vol.95
, Issue.6
, pp. 1214-1223
-
-
Lee, B.H.1
Ruoslahti, E.2
-
18
-
-
33947502315
-
hPEBP4 resists TRAIL-induced apoptosis of human prostate cancer cells by activating Akt and deactivating ERK1/2 pathways
-
PMID:17178731, doi:10.1074/jbc.M609494200
-
Li, H., Wang, X., Li, N., Qiu, J., Zhang, Y., and Cao, X. 2007. hPEBP4 resists TRAIL-induced apoptosis of human prostate cancer cells by activating Akt and deactivating ERK1/2 pathways. J. Biol. Chem. 282(7): 4943-4950. doi:10.1074/jbc.M609494200. PMID:17178731.
-
(2007)
J. Biol. Chem
, vol.282
, Issue.7
, pp. 4943-4950
-
-
Li, H.1
Wang, X.2
Li, N.3
Qiu, J.4
Zhang, Y.5
Cao, X.6
-
19
-
-
0035831556
-
Phosphatidylinositol 3-kinase/Akt activity regulates c-FLIP expression in tumor cells
-
PMID:11145953, doi:10.1074/jbc.C000569200
-
Panka, D.J., Mano, T., Suhara, T., Walsh, K., and Mier, J.W. 2001. Phosphatidylinositol 3-kinase/Akt activity regulates c-FLIP expression in tumor cells. J. Biol. Chem. 276(10): 6893-6896. doi:10.1074/jbc.C000569200. PMID:11145953.
-
(2001)
J. Biol. Chem
, vol.276
, Issue.10
, pp. 6893-6896
-
-
Panka, D.J.1
Mano, T.2
Suhara, T.3
Walsh, K.4
Mier, J.W.5
-
20
-
-
45349102347
-
Calmodulin binding to cellular FLICE-like inhibitory protein modulates Fas-induced signalling
-
PMID:18257744, doi:10.1042/BJ20071507
-
Pawar, P.S., Micoli, K.J., Ding, H., Cook, W.J., Kappes, J.C., Chen, Y., and McDonald, J.M. 2008. Calmodulin binding to cellular FLICE-like inhibitory protein modulates Fas-induced signalling. Biochem. J. 412(3): 459-468. doi:10.1042/BJ20071507. PMID:18257744.
-
(2008)
Biochem. J
, vol.412
, Issue.3
, pp. 459-468
-
-
Pawar, P.S.1
Micoli, K.J.2
Ding, H.3
Cook, W.J.4
Kappes, J.C.5
Chen, Y.6
McDonald, J.M.7
-
21
-
-
0033584823
-
Locoregional Apo2L/TRAIL eradicates intracranial human malignant glioma xenografts in athymic mice in the absence of neurotoxicity
-
PMID:10558893, doi:10.1006/bbrc.1999.1693
-
Roth, W., Isenmann, S., Naumann, U., Kügler, S., Bähr, M., Dichgans, J., et al. 1999. Locoregional Apo2L/TRAIL eradicates intracranial human malignant glioma xenografts in athymic mice in the absence of neurotoxicity. Biochem. Biophys. Res. Commun. 265(2): 479-483. doi:10.1006/bbrc.1999.1693. PMID:10558893.
-
(1999)
Biochem. Biophys. Res. Commun
, vol.265
, Issue.2
, pp. 479-483
-
-
Roth, W.1
Isenmann, S.2
Naumann, U.3
Kügler, S.4
Bähr, M.5
Dichgans, J.6
-
22
-
-
5644259587
-
Inhibitor of apoptosis proteins: Translating basic knowledge into clinical practice
-
PMID:15492230, doi:10.1158/0008-5472.CAN-04-1918
-
Schimmer, A.D. 2004. Inhibitor of apoptosis proteins: translating basic knowledge into clinical practice. Cancer Res. 64(20): 7183-7190. doi:10.1158/0008-5472.CAN-04-1918. PMID:15492230.
-
(2004)
Cancer Res
, vol.64
, Issue.20
, pp. 7183-7190
-
-
Schimmer, A.D.1
-
23
-
-
22644436371
-
Wortmannin elevates tumor necrosis factor-related apoptosis-inducing ligand sensitivity in LNCaP cells through down-regulation of IAP-2 protein
-
PMID:15995629
-
Seol, J.W., Lee, Y.J., Kang, H.S., Kim, I.S., Kim, N.S., Kwak, Y.G., et al. 2005. Wortmannin elevates tumor necrosis factor-related apoptosis-inducing ligand sensitivity in LNCaP cells through down-regulation of IAP-2 protein. Exp. Oncol. 27(2): 120-124. PMID:15995629.
-
(2005)
Exp. Oncol
, vol.27
, Issue.2
, pp. 120-124
-
-
Seol, J.W.1
Lee, Y.J.2
Kang, H.S.3
Kim, I.S.4
Kim, N.S.5
Kwak, Y.G.6
-
24
-
-
56449084185
-
Synergistic proapoptotic activity of recombinant TRAIL plus the Akt inhibitor Perifosine in acute myelogenous leukemia cells
-
PMID:19010914, doi:10.1158/0008-5472.CAN-08-2815
-
Tazzari, P.L., Tabellini, G., Ricci, F., Papa, V., Bortul, R., Chiarini, F., et al. 2008. Synergistic proapoptotic activity of recombinant TRAIL plus the Akt inhibitor Perifosine in acute myelogenous leukemia cells. Cancer Res. 68(22): 9394-9403. doi:10.1158/0008-5472.CAN-08-2815. PMID:19010914.
-
(2008)
Cancer Res
, vol.68
, Issue.22
, pp. 9394-9403
-
-
Tazzari, P.L.1
Tabellini, G.2
Ricci, F.3
Papa, V.4
Bortul, R.5
Chiarini, F.6
-
25
-
-
0023280606
-
Comparison of the effects of fluphenazine-N-mustard on dopamine binding sites and on behavior induced by apomorphine in supersensitive mice
-
PMID:3120028, doi:10.1016/0028-3908(87)90166-3
-
Thermos, K., Winkler, J.D., and Weiss, B. 1987. Comparison of the effects of fluphenazine-N-mustard on dopamine binding sites and on behavior induced by apomorphine in supersensitive mice. Neuropharmacology, 26(10): 1473-1480. doi:10.1016/0028-3908(87)90166-3. PMID:3120028.
-
(1987)
Neuropharmacology
, vol.26
, Issue.10
, pp. 1473-1480
-
-
Thermos, K.1
Winkler, J.D.2
Weiss, B.3
-
26
-
-
0020950993
-
Calcium and calmodulin in cell growth and transformation
-
PMID:6331500
-
Veigl, M.L., Vanaman, T.C., and Sedwick, W.D. 1984. Calcium and calmodulin in cell growth and transformation. Biochim. Biophys. Acta, 738(1-2): 21-48. PMID:6331500.
-
(1984)
Biochim. Biophys. Acta
, vol.738
, Issue.1-2
, pp. 21-48
-
-
Veigl, M.L.1
Vanaman, T.C.2
Sedwick, W.D.3
-
27
-
-
54249159248
-
Targeting XIAP bypasses Bcl-2-mediated resistance to TRAIL and cooperates with TRAIL to suppress pancreatic cancer growth in vitro and in vivo
-
PMID:18829553, doi:10.1158/0008-5472.CAN-08-1296
-
Vogler, M., Walczak, H., Stadel, D., Haas, T.L., Genze, F., Jovanovic, M., et al. 2008. Targeting XIAP bypasses Bcl-2-mediated resistance to TRAIL and cooperates with TRAIL to suppress pancreatic cancer growth in vitro and in vivo. Cancer Res. 68(19): 7956-7965. doi:10.1158/0008-5472.CAN-08-1296. PMID:18829553.
-
(2008)
Cancer Res
, vol.68
, Issue.19
, pp. 7956-7965
-
-
Vogler, M.1
Walczak, H.2
Stadel, D.3
Haas, T.L.4
Genze, F.5
Jovanovic, M.6
-
28
-
-
0032929520
-
Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo
-
PMID:9930862, doi:10.1038/5517
-
Walczak, H., Miller, R.E., Ariail, K., Gliniak, B., Griffith, T.S., Kubin, M., et al. 1999. Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo. Nat. Med. 5(2): 157-163. doi:10.1038/5517. PMID:9930862.
-
(1999)
Nat. Med
, vol.5
, Issue.2
, pp. 157-163
-
-
Walczak, H.1
Miller, R.E.2
Ariail, K.3
Gliniak, B.4
Griffith, T.S.5
Kubin, M.6
|