-
1
-
-
67651065502
-
Genetic characterization of TET1, TET2, and TET 3 alterations in myeloid malignancies
-
Abdel-Wahab O. Mullally A. Hedvat C. Garcia-Manero G. Patel J. Wadleigh M. et al. (2009) Genetic characterization of TET1, TET2, and TET 3 alterations in myeloid malignancies. Blood 114: 144–147.
-
(2009)
Blood
, vol.114
, pp. 144-147
-
-
Abdel-Wahab, O.1
Mullally, A.2
Hedvat, C.3
Garcia-Manero, G.4
Patel, J.5
Wadleigh, M.6
-
2
-
-
77956302639
-
Impact of JAK2V617F mutation status, allele burden, and clearance after allogeneic stem cell transplantation for myelofibrosis
-
Alchalby H. Badbaran A. Zabelina T. Kobbe G. Hahn J. Wolff D. et al. (2010) Impact of JAK2V617F mutation status, allele burden, and clearance after allogeneic stem cell transplantation for myelofibrosis. Blood 116: 3572–3581.
-
(2010)
Blood
, vol.116
, pp. 3572-3581
-
-
Alchalby, H.1
Badbaran, A.2
Zabelina, T.3
Kobbe, G.4
Hahn, J.5
Wolff, D.6
-
4
-
-
79551491928
-
Philadelphia-negative classical myeloproliferative neoplasms: critical concepts and management recommendations from European LeukemiaNet
-
Barbui T. Barosi G. Birgegard G. Cervantes F. Finazzi G. Griesshammer M. et al. (2011) Philadelphia-negative classical myeloproliferative neoplasms: critical concepts and management recommendations from European LeukemiaNet. J Clin Oncol 29: 761–770.
-
(2011)
J Clin Oncol
, vol.29
, pp. 761-770
-
-
Barbui, T.1
Barosi, G.2
Birgegard, G.3
Cervantes, F.4
Finazzi, G.5
Griesshammer, M.6
-
7
-
-
77950977381
-
Two routes to leukemic transformation after a JAK2 mutation-positive myeloproliferative neoplasm
-
Beer P.A. Delhommeau F. Le Couedic J.P. Dawson M.A. Chen E. Bareford D. et al. (2010) Two routes to leukemic transformation after a JAK2 mutation-positive myeloproliferative neoplasm. Blood 115: 2891–2900.
-
(2010)
Blood
, vol.115
, pp. 2891-2900
-
-
Beer, P.A.1
Delhommeau, F.2
Le Couedic, J.P.3
Dawson, M.A.4
Chen, E.5
Bareford, D.6
-
9
-
-
84984760593
-
Somatic and germline genetics at the JAK2 locus
-
Campbell P.J. (2009) Somatic and germline genetics at the JAK2 locus. Nat Genet 41: 385–386.
-
(2009)
Nat Genet
, vol.41
, pp. 385-386
-
-
Campbell, P.J.1
-
10
-
-
33845436745
-
The myeloproliferative disorders
-
Campbell P.J. Green A.R. (2006) The myeloproliferative disorders. N Engl J Med 355: 2452–2466.
-
(2006)
N Engl J Med
, vol.355
, pp. 2452-2466
-
-
Campbell, P.J.1
Green, A.R.2
-
11
-
-
0031003622
-
Identification of ‘short-lived’ and ‘long-lived’ patients at presentation of idiopathic myelofibrosis
-
Cervantes F. Pereira A. Esteve J. Rafel M. Cobo F. Rozman C. et al. (1997) Identification of ‘short-lived’ and ‘long-lived’ patients at presentation of idiopathic myelofibrosis. Br J Haematol 97: 635–640.
-
(1997)
Br J Haematol
, vol.97
, pp. 635-640
-
-
Cervantes, F.1
Pereira, A.2
Esteve, J.3
Rafel, M.4
Cobo, F.5
Rozman, C.6
-
12
-
-
63849328927
-
New prognostic scoring system for primary myelofibrosis based on a study of the International Working Group for Myelofibrosis Research and Treatment
-
Cervantes F. Dupriez B. Pereira A. Passamonti F. Reilly J.T. Morra E. et al. (2009) New prognostic scoring system for primary myelofibrosis based on a study of the International Working Group for Myelofibrosis Research and Treatment. Blood 113 (13): 2895–2901.
-
(2009)
Blood
, vol.113
, Issue.13
, pp. 2895-2901
-
-
Cervantes, F.1
Dupriez, B.2
Pereira, A.3
Passamonti, F.4
Reilly, J.T.5
Morra, E.6
-
14
-
-
0001639195
-
Some speculations on the myeloproliferative syndromes
-
Dameshek W. (1951) Some speculations on the myeloproliferative syndromes. Blood 6: 372–375.
-
(1951)
Blood
, vol.6
, pp. 372-375
-
-
Dameshek, W.1
-
17
-
-
80053505459
-
Companies hope for kinase inhibitor JAKpot
-
Dolgin E. (2011) Companies hope for kinase inhibitor JAKpot. Nat Rev Drug Discov 10: 717–718.
-
(2011)
Nat Rev Drug Discov
, vol.10
, pp. 717-718
-
-
Dolgin, E.1
-
19
-
-
0029767865
-
Prognostic factors in agnogenic myeloid metaplasia: a report on 195 cases with a new scoring system
-
Dupriez B. Morel P. Demory J.L. Lai J.L. Simon M. Plantier I. et al. (1996) Prognostic factors in agnogenic myeloid metaplasia: a report on 195 cases with a new scoring system. Blood 88: 1013–1018.
-
(1996)
Blood
, vol.88
, pp. 1013-1018
-
-
Dupriez, B.1
Morel, P.2
Demory, J.L.3
Lai, J.L.4
Simon, M.5
Plantier, I.6
-
21
-
-
79952087335
-
DIPSS plus: a refined Dynamic International Prognostic Scoring System for primary myelofibrosis that incorporates prognostic information from karyotype, platelet count, and transfusion status
-
Gangat N. Caramazza D. Vaidya R. George G. Begna K. Schwager S. et al. (2011) DIPSS plus: a refined Dynamic International Prognostic Scoring System for primary myelofibrosis that incorporates prognostic information from karyotype, platelet count, and transfusion status. J Clin Oncol 29: 392–397.
-
(2011)
J Clin Oncol
, vol.29
, pp. 392-397
-
-
Gangat, N.1
Caramazza, D.2
Vaidya, R.3
George, G.4
Begna, K.5
Schwager, S.6
-
22
-
-
0035892104
-
Erythropoiesis in the absence of janus-kinase 2: BCR-ABL induces red cell formation in JAK2(-/-) hematopoietic progenitors
-
Ghaffari S. Kitidis C. Fleming M.D. Neubauer H. Pfeffer K. Lodish H.F. (2001) Erythropoiesis in the absence of janus-kinase 2: BCR-ABL induces red cell formation in JAK2(-/-) hematopoietic progenitors. Blood 98: 2948–2957.
-
(2001)
Blood
, vol.98
, pp. 2948-2957
-
-
Ghaffari, S.1
Kitidis, C.2
Fleming, M.D.3
Neubauer, H.4
Pfeffer, K.5
Lodish, H.F.6
-
23
-
-
0033135848
-
Allogeneic stem cell transplantation for agnogenic myeloid metaplasia: a European Group for Blood and Marrow Transplantation, Societe Francaise de Greffe de Moelle, Gruppo Italiano per il Trapianto del Midollo Osseo, and Fred Hutchinson Cancer Research Center Collaborative Study
-
Guardiola P. Anderson J.E. Bandini G. Cervantes F. Runde V. Arcese W. et al. (1999) Allogeneic stem cell transplantation for agnogenic myeloid metaplasia: a European Group for Blood and Marrow Transplantation, Societe Francaise de Greffe de Moelle, Gruppo Italiano per il Trapianto del Midollo Osseo, and Fred Hutchinson Cancer Research Center Collaborative Study. Blood 93: 2831–2838.
-
(1999)
Blood
, vol.93
, pp. 2831-2838
-
-
Guardiola, P.1
Anderson, J.E.2
Bandini, G.3
Cervantes, F.4
Runde, V.5
Arcese, W.6
-
24
-
-
80052184481
-
Safety and efficacy of everolimus, a mTOR inhibitor, as single agent in a phase 1 / 2 study in patients with myelofibrosis
-
Guglielmelli P. Barosi G. Rambaldi A. Marchioli R. Masciulli A. Tozzi L. et al. (2011 a) Safety and efficacy of everolimus, a mTOR inhibitor, as single agent in a phase 1 / 2 study in patients with myelofibrosis. Blood 118: 2069–2076.
-
(2011)
Blood
, vol.118
, pp. 2069-2076
-
-
Guglielmelli, P.1
Barosi, G.2
Rambaldi, A.3
Marchioli, R.4
Masciulli, A.5
Tozzi, L.6
-
25
-
-
70349580685
-
Identification of patients with poorer survival in primary myelofibrosis based on the burden of JAK2V617F mutated allele
-
Guglielmelli P. Barosi G. Specchia G. Rambaldi A. Lo Coco F. Antonioli E. et al. (2009) Identification of patients with poorer survival in primary myelofibrosis based on the burden of JAK2V617F mutated allele. Blood 114: 1477–1483.
-
(2009)
Blood
, vol.114
, pp. 1477-1483
-
-
Guglielmelli, P.1
Barosi, G.2
Specchia, G.3
Rambaldi, A.4
Lo Coco, F.5
Antonioli, E.6
-
27
-
-
70349160401
-
A retrospective comparison of conventional intensity conditioning and reduced-intensity conditioning for allogeneic hematopoietic cell transplantation in myelofibrosis
-
Gupta V. Kroger N. Aschan J. Xu W. Leber B. Dalley C. et al. (2009) A retrospective comparison of conventional intensity conditioning and reduced-intensity conditioning for allogeneic hematopoietic cell transplantation in myelofibrosis. Bone Marrow Transplant 44: 317–320.
-
(2009)
Bone Marrow Transplant
, vol.44
, pp. 317-320
-
-
Gupta, V.1
Kroger, N.2
Aschan, J.3
Xu, W.4
Leber, B.5
Dalley, C.6
-
28
-
-
47049098437
-
Lestaurtinib (CEP701) is a JAK2 inhibitor that suppresses JAK2/STAT5 signaling and the proliferation of primary erythroid cells from patients with myeloproliferative disorders
-
Hexner E.O. Serdikoff C. Jan M. Swider C.R. Robinson C. Yang S. et al. (2008) Lestaurtinib (CEP701) is a JAK2 inhibitor that suppresses JAK2/STAT5 signaling and the proliferation of primary erythroid cells from patients with myeloproliferative disorders. Blood 111: 5663–5671.
-
(2008)
Blood
, vol.111
, pp. 5663-5671
-
-
Hexner, E.O.1
Serdikoff, C.2
Jan, M.3
Swider, C.R.4
Robinson, C.5
Yang, S.6
-
29
-
-
67649976491
-
PEG-IFN-alpha-2a therapy in patients with myelofibrosis: a study of the French Groupe d'Etudes des Myelofibroses (GEM) and France Intergroupe des syndromes Myeloproliferatifs (FIM)
-
Ianotto J.C. Kiladjian J.J. Demory J.L. Roy L. Boyer F. Rey J. et al. (2009) PEG-IFN-alpha-2a therapy in patients with myelofibrosis: a study of the French Groupe d'Etudes des Myelofibroses (GEM) and France Intergroupe des syndromes Myeloproliferatifs (FIM). Br J Haematol 146: 223–225.
-
(2009)
Br J Haematol
, vol.146
, pp. 223-225
-
-
Ianotto, J.C.1
Kiladjian, J.J.2
Demory, J.L.3
Roy, L.4
Boyer, F.5
Rey, J.6
-
30
-
-
17844383458
-
A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
-
James C. Ugo V. Le Couedic J.P. Staerk J. Delhommeau F. Lacout C. et al. (2005) A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature 434: 1144–1148.
-
(2005)
Nature
, vol.434
, pp. 1144-1148
-
-
James, C.1
Ugo, V.2
Le Couedic, J.P.3
Staerk, J.4
Delhommeau, F.5
Lacout, C.6
-
32
-
-
63449099560
-
JAK2 haplotype is a major risk factor for the development of myeloproliferative neoplasms
-
Jones A.V. Chase A. Silver R.T. Oscier D. Zoi K. Wang Y.L. et al. (2009) JAK2 haplotype is a major risk factor for the development of myeloproliferative neoplasms. Nat Genet 41: 446–449.
-
(2009)
Nat Genet
, vol.41
, pp. 446-449
-
-
Jones, A.V.1
Chase, A.2
Silver, R.T.3
Oscier, D.4
Zoi, K.5
Wang, Y.L.6
-
33
-
-
33847083481
-
Hematopoietic cell transplantation as curative therapy for idiopathic myelofibrosis, advanced polycythemia vera, and essential thrombocythemia
-
Kerbauy D.M. Gooley T.A. Sale G.E. Flowers M.E. Doney K.C. Georges G.E. et al. (2007). Hematopoietic cell transplantation as curative therapy for idiopathic myelofibrosis, advanced polycythemia vera, and essential thrombocythemia. Biol Blood Marrow Transplant 13: 355–365.
-
(2007)
Biol Blood Marrow Transplant
, vol.13
, pp. 355-365
-
-
Kerbauy, D.M.1
Gooley, T.A.2
Sale, G.E.3
Flowers, M.E.4
Doney, K.C.5
Georges, G.E.6
-
34
-
-
54049141336
-
Pegylated interferon-alfa-2a induces complete hematologic and molecular responses with low toxicity in polycythemia vera
-
Kiladjian J.J. Cassinat B. Chevret S. Turlure P. Cambier N. Roussel M. et al. (2008) Pegylated interferon-alfa-2a induces complete hematologic and molecular responses with low toxicity in polycythemia vera. Blood 112: 3065–3072.
-
(2008)
Blood
, vol.112
, pp. 3065-3072
-
-
Kiladjian, J.J.1
Cassinat, B.2
Chevret, S.3
Turlure, P.4
Cambier, N.5
Roussel, M.6
-
35
-
-
77955716180
-
Clonal analysis of erythroid progenitors suggests that pegylated interferon alpha-2a treatment targets JAK2V617F clones without affecting TET 2 mutant cells
-
Kiladjian J.J. Masse A. Cassinat B. Mokrani H. Teyssandier I. Le Couedic J.P. et al. (2010) Clonal analysis of erythroid progenitors suggests that pegylated interferon alpha-2a treatment targets JAK2V617F clones without affecting TET 2 mutant cells. Leukemia 24: 1519–1523.
-
(2010)
Leukemia
, vol.24
, pp. 1519-1523
-
-
Kiladjian, J.J.1
Masse, A.2
Cassinat, B.3
Mokrani, H.4
Teyssandier, I.5
Le Couedic, J.P.6
-
36
-
-
79955947379
-
The renaissance of interferon therapy for the treatment of myeloid malignancies
-
Kiladjian J.J. Mesa R.A. Hoffman R. (2011) The renaissance of interferon therapy for the treatment of myeloid malignancies. Blood 117: 4706–4715.
-
(2011)
Blood
, vol.117
, pp. 4706-4715
-
-
Kiladjian, J.J.1
Mesa, R.A.2
Hoffman, R.3
-
37
-
-
63449127583
-
A germline JAK2 SNP is associated with predisposition to the development of JAK2(V617F)-positive myeloproliferative neoplasms
-
Kilpivaara O. Mukherjee S. Schram A.M. Wadleigh M. Mullally A. Ebert B.L. et al. (2009) A germline JAK2 SNP is associated with predisposition to the development of JAK2(V617F)-positive myeloproliferative neoplasms. Nat Genet 41: 455–459.
-
(2009)
Nat Genet
, vol.41
, pp. 455-459
-
-
Kilpivaara, O.1
Mukherjee, S.2
Schram, A.M.3
Wadleigh, M.4
Mullally, A.5
Ebert, B.L.6
-
38
-
-
79960145108
-
Genome integrity of myeloproliferative neoplasms in chronic phase and during disease progression
-
Klampfl T. Harutyunyan A. Berg T. Gisslinger B. Schalling M. Bagienski K. et al. (2011) Genome integrity of myeloproliferative neoplasms in chronic phase and during disease progression. Blood 118: 167–176.
-
(2011)
Blood
, vol.118
, pp. 167-176
-
-
Klampfl, T.1
Harutyunyan, A.2
Berg, T.3
Gisslinger, B.4
Schalling, M.5
Bagienski, K.6
-
39
-
-
77951031498
-
Efficacy of the JAK2 inhibitor INCB 16562 in a murine model of MPLW515L-induced thrombocytosis and myelofibrosis
-
Koppikar P. Abdel-Wahab O. Hedvat C. Marubayashi S. Patel J. Goel A. et al. (2010) Efficacy of the JAK2 inhibitor INCB 16562 in a murine model of MPLW515L-induced thrombocytosis and myelofibrosis. Blood 115: 2919–2927.
-
(2010)
Blood
, vol.115
, pp. 2919-2927
-
-
Koppikar, P.1
Abdel-Wahab, O.2
Hedvat, C.3
Marubayashi, S.4
Patel, J.5
Goel, A.6
-
41
-
-
61949135475
-
JAK2-V617F-triggered preemptive and salvage adoptive immunotherapy with donor-lymphocyte infusion in patients with myelofibrosis after allogeneic stem cell transplantation
-
Kroger N. Alchalby H. Klyuchnikov E. Badbaran A. Hildebrandt Y. Ayuk F. et al. (2009 a) JAK2-V617F-triggered preemptive and salvage adoptive immunotherapy with donor-lymphocyte infusion in patients with myelofibrosis after allogeneic stem cell transplantation. Blood 113: 1866–1868.
-
(2009)
Blood
, vol.113
, pp. 1866-1868
-
-
Kroger, N.1
Alchalby, H.2
Klyuchnikov, E.3
Badbaran, A.4
Hildebrandt, Y.5
Ayuk, F.6
-
42
-
-
73949084969
-
Allogeneic stem cell transplantation after reduced-intensity conditioning in patients with myelofibrosis: a prospective, multicenter study of the Chronic Leukemia Working Party of the European Group for Blood and Marrow Transplantation
-
Kroger N. Holler E. Kobbe G. Bornhauser M. Schwerdtfeger R. Baurmann H. et al. (2009 b) Allogeneic stem cell transplantation after reduced-intensity conditioning in patients with myelofibrosis: a prospective, multicenter study of the Chronic Leukemia Working Party of the European Group for Blood and Marrow Transplantation. Blood 114: 5264–5270.
-
(2009)
Blood
, vol.114
, pp. 5264-5270
-
-
Kroger, N.1
Holler, E.2
Kobbe, G.3
Bornhauser, M.4
Schwerdtfeger, R.5
Baurmann, H.6
-
43
-
-
20244369569
-
Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
-
Levine R.L. Wadleigh M. Cools J. Ebert B.L. Wernig G. Huntly B.J. et al. (2005) Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell 7: 387–397.
-
(2005)
Cancer Cell
, vol.7
, pp. 387-397
-
-
Levine, R.L.1
Wadleigh, M.2
Cools, J.3
Ebert, B.L.4
Wernig, G.5
Huntly, B.J.6
-
44
-
-
77956578342
-
JAK2V617F impairs hematopoietic stem cell function in a conditional knock-in mouse model of JAK2V617F-positive essential thrombocythemia
-
Li J. Spensberger D. Ahn J.S. Anand S. Beer P.A. Ghevaert C. et al. (2010) JAK2V617F impairs hematopoietic stem cell function in a conditional knock-in mouse model of JAK2V617F-positive essential thrombocythemia. Blood 116: 1528–1538.
-
(2010)
Blood
, vol.116
, pp. 1528-1538
-
-
Li, J.1
Spensberger, D.2
Ahn, J.S.3
Anand, S.4
Beer, P.A.5
Ghevaert, C.6
-
46
-
-
79751486147
-
JAK2V617F-mediated phosphorylation of PRMT 5 downregulates its methyltransferase activity and promotes myeloproliferation
-
Liu F. Zhao X. Perna F. Wang L. Koppikar P. Abdel-Wahab O. et al. (2011) JAK2V617F-mediated phosphorylation of PRMT 5 downregulates its methyltransferase activity and promotes myeloproliferation. Cancer Cell 19: 283–294.
-
(2011)
Cancer Cell
, vol.19
, pp. 283-294
-
-
Liu, F.1
Zhao, X.2
Perna, F.3
Wang, L.4
Koppikar, P.5
Abdel-Wahab, O.6
-
49
-
-
72849159485
-
Chromosome studies on normal and leukemic human leukocytes
-
Nowell P.C. Hungerford D.A. (1960) Chromosome studies on normal and leukemic human leukocytes. J Natl Cancer Inst 25: 85–109.
-
(1960)
J Natl Cancer Inst
, vol.25
, pp. 85-109
-
-
Nowell, P.C.1
Hungerford, D.A.2
-
50
-
-
84993724886
-
When the brakes are lost: LNK dysfunction in mice, men, and myeloproliferative neoplasms
-
Oh S.T. (2011) When the brakes are lost: LNK dysfunction in mice, men, and myeloproliferative neoplasms. Ther Adv Hematol 2: 11–19.
-
(2011)
Ther Adv Hematol
, vol.2
, pp. 11-19
-
-
Oh, S.T.1
-
51
-
-
77953485892
-
Novel mutations in the inhibitory adaptor protein LNK drive JAK-STAT signaling in patients with myeloproliferative neoplasms
-
Oh S.T. Simonds E.F. Jones C. Hale M.B. Goltsev Y. Gibbs K.D. Jr et al. (2010) Novel mutations in the inhibitory adaptor protein LNK drive JAK-STAT signaling in patients with myeloproliferative neoplasms. Blood 116: 988–992.
-
(2010)
Blood
, vol.116
, pp. 988-992
-
-
Oh, S.T.1
Simonds, E.F.2
Jones, C.3
Hale, M.B.4
Goltsev, Y.5
Gibbs, K.D.6
-
53
-
-
70350111160
-
The ‘GGCC’ haplotype of JAK2 confers susceptibility to JAK2 exon 12 mutation-positive polycythemia vera
-
Leukemia
-
Olcaydu D. Skoda R.C. Looser R. Li S. Cazzola M. Pietra D. et al. (2009 b) The ‘GGCC’ haplotype of JAK2 confers susceptibility to JAK2 exon 12 mutation-positive polycythemia vera. Leukemia 23: 1924–1926.
-
(2009)
, vol.23
, pp. 1924-1926
-
-
Olcaydu, D.1
Skoda, R.C.2
Looser, R.3
Li, S.4
Cazzola, M.5
Pietra, D.6
-
54
-
-
79952333359
-
Safety and efficacy of TG101348, a selective JAK2 inhibitor, in myelofibrosis
-
Pardanani A. Gotlib J.R. Jamieson C. Cortes J.E. Talpaz M. Stone R.M. et al. (2011) Safety and efficacy of TG101348, a selective JAK2 inhibitor, in myelofibrosis. J Clin Oncol 29: 789–796.
-
(2011)
J Clin Oncol
, vol.29
, pp. 789-796
-
-
Pardanani, A.1
Gotlib, J.R.2
Jamieson, C.3
Cortes, J.E.4
Talpaz, M.5
Stone, R.M.6
-
55
-
-
77950352432
-
A dynamic prognostic model to predict survival in primary myelofibrosis: a study by the IWG-MRT (International Working Group for Myeloproliferative Neoplasms Research and Treatment)
-
Passamonti F. Cervantes F. Vannucchi A.M. Morra E. Rumi E. Pereira A. et al. (2010) A dynamic prognostic model to predict survival in primary myelofibrosis: a study by the IWG-MRT (International Working Group for Myeloproliferative Neoplasms Research and Treatment). Blood 115: 1703–1708.
-
(2010)
Blood
, vol.115
, pp. 1703-1708
-
-
Passamonti, F.1
Cervantes, F.2
Vannucchi, A.M.3
Morra, E.4
Rumi, E.5
Pereira, A.6
-
56
-
-
54349127113
-
Allogeneic hematopoietic stem cell transplantation in myelofibrosis: the 20-year experience of the Gruppo Italiano Trapianto di Midollo Osseo (GITMO)
-
Patriarca F. Bacigalupo A. Sperotto A. Isola M. Soldano F. Bruno B. et al. (2008) Allogeneic hematopoietic stem cell transplantation in myelofibrosis: the 20-year experience of the Gruppo Italiano Trapianto di Midollo Osseo (GITMO). Haematologica 93: 1514-1522.
-
(2008)
Haematologica
, vol.93
, pp. 1514-1522
-
-
Patriarca, F.1
Bacigalupo, A.2
Sperotto, A.3
Isola, M.4
Soldano, F.5
Bruno, B.6
-
57
-
-
77957945719
-
Depletion of L3MBTL1 promotes the erythroid differentiation of human hematopoietic progenitor cells: possible role in 20q- polycythemia vera
-
Perna F. Gurvich N. Hoya-Arias R. Abdel-Wahab O. Levine R.L. Asai T. et al. (2010) Depletion of L3MBTL1 promotes the erythroid differentiation of human hematopoietic progenitor cells: possible role in 20q- polycythemia vera. Blood 116: 2812–2821.
-
(2010)
Blood
, vol.116
, pp. 2812-2821
-
-
Perna, F.1
Gurvich, N.2
Hoya-Arias, R.3
Abdel-Wahab, O.4
Levine, R.L.5
Asai, T.6
-
58
-
-
33746437130
-
MPLW515L Is a Novel Somatic Activating Mutation in Myelofibrosis with Myeloid Metaplasia
-
Pikman Y. Lee B.H. Mercher T. McDowell E. Ebert B.L. Gozo M. et al. (2006) MPLW515L Is a Novel Somatic Activating Mutation in Myelofibrosis with Myeloid Metaplasia. PLoS Med 3 (7): e270.
-
(2006)
PLoS Med
, vol.3
, Issue.7
, pp. e270
-
-
Pikman, Y.1
Lee, B.H.2
Mercher, T.3
McDowell, E.4
Ebert, B.L.5
Gozo, M.6
-
59
-
-
79960062301
-
TET 2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis
-
Quivoron C. Couronne L. Della Valle V. Lopez C.K. Plo I. Wagner-Ballon O. et al. (2011) TET 2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis. Cancer Cell 20: 25–38.
-
(2011)
Cancer Cell
, vol.20
, pp. 25-38
-
-
Quivoron, C.1
Couronne, L.2
Della Valle, V.3
Lopez, C.K.4
Plo, I.5
Wagner-Ballon, O.6
-
60
-
-
77955168425
-
A pilot study of the Histone-Deacetylase inhibitor Givinostat in patients with JAK2V617F positive chronic myeloproliferative neoplasms
-
Rambaldi A. Dellacasa C.M. Finazzi G. Carobbio A. Ferrari M.L. Guglielmelli P. et al. (2010) A pilot study of the Histone-Deacetylase inhibitor Givinostat in patients with JAK2V617F positive chronic myeloproliferative neoplasms. Br J Haematol 150: 446–455.
-
(2010)
Br J Haematol
, vol.150
, pp. 446-455
-
-
Rambaldi, A.1
Dellacasa, C.M.2
Finazzi, G.3
Carobbio, A.4
Ferrari, M.L.5
Guglielmelli, P.6
-
61
-
-
78651334433
-
Allogeneic haematopoietic stem cell transplantation for myelofibrosis: a report of the Societe Francaise de Greffe de Moelle et de Therapie Cellulaire (SFGM-TC)
-
Robin M. Tabrizi R. Mohty M. Furst S. Michallet M. Bay J.O. et al. Allogeneic haematopoietic stem cell transplantation for myelofibrosis: a report of the Societe Francaise de Greffe de Moelle et de Therapie Cellulaire (SFGM-TC). Br J Haematol 152: 331–339.
-
Br J Haematol
, vol.152
, pp. 331-339
-
-
Robin, M.1
Tabrizi, R.2
Mohty, M.3
Furst, S.4
Michallet, M.5
Bay, J.O.6
-
63
-
-
67149091317
-
Interferon regulatory factor-2 protects quiescent hematopoietic stem cells from type I interferon-dependent exhaustion
-
Sato T. Onai N. Yoshihara H. Arai F. Suda T. Ohteki T. (2009) Interferon regulatory factor-2 protects quiescent hematopoietic stem cells from type I interferon-dependent exhaustion. Nat Med 15: 696–700.
-
(2009)
Nat Med
, vol.15
, pp. 696-700
-
-
Sato, T.1
Onai, N.2
Yoshihara, H.3
Arai, F.4
Suda, T.5
Ohteki, T.6
-
64
-
-
33845526943
-
JAK2 seems to be a typical cooperating mutation in therapy-related t(8;21)/ AML1-ETO-positive AML
-
Schnittger S. Bacher U. Kern W. Haferlach C. Haferlach T. (2007) JAK2 seems to be a typical cooperating mutation in therapy-related t(8;21)/ AML1-ETO-positive AML. Leukemia 21: 183–184.
-
(2007)
Leukemia
, vol.21
, pp. 183-184
-
-
Schnittger, S.1
Bacher, U.2
Kern, W.3
Haferlach, C.4
Haferlach, T.5
-
65
-
-
33749358349
-
Progenitors homozygous for the V617F mutation occur in most patients with polycythemia vera, but not essential thrombocythemia
-
Scott L.M. Scott M.A. Campbell P.J. Green A.R. (2006) Progenitors homozygous for the V617F mutation occur in most patients with polycythemia vera, but not essential thrombocythemia. Blood 108: 2435–2437.
-
(2006)
Blood
, vol.108
, pp. 2435-2437
-
-
Scott, L.M.1
Scott, M.A.2
Campbell, P.J.3
Green, A.R.4
-
67
-
-
60549112374
-
Use of molecular testing to identify a cluster of patients with polycythemia vera in eastern Pennsylvania
-
Seaman V. Jumaan A. Yanni E. Lewis B. Neyer J. Roda P. et al. (2009) Use of molecular testing to identify a cluster of patients with polycythemia vera in eastern Pennsylvania. Cancer Epidemiol Biomarkers Prev 18: 534–540.
-
(2009)
Cancer Epidemiol Biomarkers Prev
, vol.18
, pp. 534-540
-
-
Seaman, V.1
Jumaan, A.2
Yanni, E.3
Lewis, B.4
Neyer, J.5
Roda, P.6
-
68
-
-
79959232873
-
Recombinant interferon-alpha may retard progression of early primary myelofibrosis: a preliminary report
-
Silver R.T. Vandris K. Goldman J.J. (2011) Recombinant interferon-alpha may retard progression of early primary myelofibrosis: a preliminary report. Blood 117: 6669–6672.
-
(2011)
Blood
, vol.117
, pp. 6669-6672
-
-
Silver, R.T.1
Vandris, K.2
Goldman, J.J.3
-
69
-
-
75449097356
-
Improved outcomes using tacrolimus / sirolimus for graft-versus-host disease prophylaxis with a reduced-intensity conditioning regimen for allogeneic hematopoietic cell transplant as treatment of myelofibrosis
-
Snyder D.S. Palmer J. Gaal K. Stein A.S. Pullarkat V. Sahebi F. et al. (2010) Improved outcomes using tacrolimus / sirolimus for graft-versus-host disease prophylaxis with a reduced-intensity conditioning regimen for allogeneic hematopoietic cell transplant as treatment of myelofibrosis. Biol Blood Marrow Transplant 16: 281–286.
-
(2010)
Biol Blood Marrow Transplant
, vol.16
, pp. 281-286
-
-
Snyder, D.S.1
Palmer, J.2
Gaal, K.3
Stein, A.S.4
Pullarkat, V.5
Sahebi, F.6
-
70
-
-
23944440464
-
Hematopoietic cell transplantation (HCT)-specific comorbidity index: a new tool for risk assessment before allogeneic HCT
-
Sorror M.L. Maris M.B. Storb R. Baron F. Sandmaier B.M. Maloney D.G. et al. (2005) Hematopoietic cell transplantation (HCT)-specific comorbidity index: a new tool for risk assessment before allogeneic HCT. Blood 106: 2912–2919.
-
(2005)
Blood
, vol.106
, pp. 2912-2919
-
-
Sorror, M.L.1
Maris, M.B.2
Storb, R.3
Baron, F.4
Sandmaier, B.M.5
Maloney, D.G.6
-
71
-
-
47649121826
-
The revised World Health Organization diagnostic criteria for polycythemia vera, essential thrombocytosis, and primary myelofibrosis: an alternative proposal
-
Spivak J.L. Silver R.T. (2008) The revised World Health Organization diagnostic criteria for polycythemia vera, essential thrombocytosis, and primary myelofibrosis: an alternative proposal. Blood 112: 231–239.
-
(2008)
Blood
, vol.112
, pp. 231-239
-
-
Spivak, J.L.1
Silver, R.T.2
-
72
-
-
80053629571
-
Disruption of the ASXL 1 gene is frequent in primary, post-essential thrombocytosis and post-polycythemia vera myelofibrosis, but not essential thrombocytosis or polycythemia vera: analysis of molecular genetics and clinical phenotypes
-
Stein B.L. Williams D.M. O'Keefe C. Rogers O. Ingersoll R.G. Spivak J.L. et al. (2011) Disruption of the ASXL 1 gene is frequent in primary, post-essential thrombocytosis and post-polycythemia vera myelofibrosis, but not essential thrombocytosis or polycythemia vera: analysis of molecular genetics and clinical phenotypes. Haematologica 96: 1462–1469.
-
(2011)
Haematologica
, vol.96
, pp. 1462-1469
-
-
Stein, B.L.1
Williams, D.M.2
O'Keefe, C.3
Rogers, O.4
Ingersoll, R.G.5
Spivak, J.L.6
-
73
-
-
79960256611
-
for the International Agency for Research on Cancer, World Health Organization and Louis A. Duhring Fund
-
4th ed. Lyon, France International Agency for Research on Cancer available at: http://hdl.library.upenn.edu/1017.12/366308
-
Swerdlow S.H., for the International Agency for Research on Cancer, World Health Organization and Louis A. Duhring Fund (2008) WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues, 4th ed. Lyon, France: International Agency for Research on Cancer, p. 439, available at: http://hdl.library.upenn.edu/1017.12/366308.
-
(2008)
WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues
, pp. 439
-
-
Swerdlow, S.H.1
-
74
-
-
42449124578
-
Low JAK2V617F allele burden in primary myelofibrosis, compared to either a higher allele burden or unmutated status, is associated with inferior overall and leukemia-free survival
-
Tefferi A. Lasho T.L. Huang J. Finke C. Mesa R.A. Li C.Y. et al. (2008) Low JAK2V617F allele burden in primary myelofibrosis, compared to either a higher allele burden or unmutated status, is associated with inferior overall and leukemia-free survival. Leukemia 22: 756–761.
-
(2008)
Leukemia
, vol.22
, pp. 756-761
-
-
Tefferi, A.1
Lasho, T.L.2
Huang, J.3
Finke, C.4
Mesa, R.A.5
Li, C.Y.6
-
75
-
-
78149453788
-
Treatment of progression of Philadelphia-negative myeloproliferative neoplasms to myelodysplastic syndrome or acute myeloid leukemia by azacitidine: a report on 54 cases on the behalf of the Groupe Francophone des Myelodysplasies (GFM)
-
Thepot S. Itzykson R. Seegers V. Raffoux E. Quesnel B. Chait Y. et al. (2010) Treatment of progression of Philadelphia-negative myeloproliferative neoplasms to myelodysplastic syndrome or acute myeloid leukemia by azacitidine: a report on 54 cases on the behalf of the Groupe Francophone des Myelodysplasies (GFM). Blood 116: 3735–3742.
-
(2010)
Blood
, vol.116
, pp. 3735-3742
-
-
Thepot, S.1
Itzykson, R.2
Seegers, V.3
Raffoux, E.4
Quesnel, B.5
Chait, Y.6
-
76
-
-
79957611312
-
Essential thrombocythemia versus early primary myelofibrosis: a multicenter study to validate the WHO classification
-
Thiele J. Kvasnicka H.M. Mullauer L. Buxhofer-Ausch V. Gisslinger B. Gisslinger H. (2011) Essential thrombocythemia versus early primary myelofibrosis: a multicenter study to validate the WHO classification. Blood 117: 5710–5718.
-
(2011)
Blood
, vol.117
, pp. 5710-5718
-
-
Thiele, J.1
Kvasnicka, H.M.2
Mullauer, L.3
Buxhofer-Ausch, V.4
Gisslinger, B.5
Gisslinger, H.6
-
77
-
-
20444426803
-
Lnk inhibits erythropoiesis and Epo-dependent JAK2 activation and downstream signaling pathways
-
Tong W. Zhang J. Lodish H.F. (2005) Lnk inhibits erythropoiesis and Epo-dependent JAK2 activation and downstream signaling pathways. Blood 105: 4604–4612.
-
(2005)
Blood
, vol.105
, pp. 4604-4612
-
-
Tong, W.1
Zhang, J.2
Lodish, H.F.3
-
78
-
-
84993730731
-
JAK2 allele burden in the myeloproliferative neoplasms: effects on phenotype, prognosis and change with treatment
-
Vannucchi A.M. Pieri L. Guglielmelli P. (2011) JAK2 allele burden in the myeloproliferative neoplasms: effects on phenotype, prognosis and change with treatment. Ther Adv Hematol 2: 21–32.
-
(2011)
Ther Adv Hematol
, vol.2
, pp. 21-32
-
-
Vannucchi, A.M.1
Pieri, L.2
Guglielmelli, P.3
-
80
-
-
77956696835
-
Safety and efficacy of INCB018424, a JAK1 and JAK2 inhibitor, in myelofibrosis
-
Verstovsek S. Kantarjian H. Mesa R.A. Pardanani A.D. Cortes-Franco J. Thomas D.A. et al. (2010) Safety and efficacy of INCB018424, a JAK1 and JAK2 inhibitor, in myelofibrosis. N Engl J Med 363: 1117–1127.
-
(2010)
N Engl J Med
, vol.363
, pp. 1117-1127
-
-
Verstovsek, S.1
Kantarjian, H.2
Mesa, R.A.3
Pardanani, A.D.4
Cortes-Franco, J.5
Thomas, D.A.6
-
82
-
-
33744490974
-
Expression of Jak2V617F causes a polycythemia vera-like disease with associated myelofibrosis in a murine bone marrow transplant model
-
Wernig G. Mercher T. Okabe R. Levine R.L. Lee B.H. Gilliland D.G. (2006) Expression of Jak2V617F causes a polycythemia vera-like disease with associated myelofibrosis in a murine bone marrow transplant model. Blood 107: 4274–4281.
-
(2006)
Blood
, vol.107
, pp. 4274-4281
-
-
Wernig, G.1
Mercher, T.2
Okabe, R.3
Levine, R.L.4
Lee, B.H.5
Gilliland, D.G.6
-
83
-
-
33846807560
-
Novel tumor antigens elicit anti-tumor humoral immune reactions in a subset of patients with polycythemia vera
-
Xiong Z. Yan Y. Liu E. Silver R.T. Verstovsek S. Yang F. et al. (2007) Novel tumor antigens elicit anti-tumor humoral immune reactions in a subset of patients with polycythemia vera. Clin Immunol 122: 279–287.
-
(2007)
Clin Immunol
, vol.122
, pp. 279-287
-
-
Xiong, Z.1
Yan, Y.2
Liu, E.3
Silver, R.T.4
Verstovsek, S.5
Yang, F.6
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