The Obesity-Mortality Paradox in Patients With Heart Failure in Taiwan and a Collaborative Meta-Analysis for East Asian Patients

American Journal of Cardiology

Volumn 118, Issue 7, 2016, Pages 1011-1018

  Lin, Gen Min ^a,b,c   Li, Yi Hwei ^c   Yin, Wei Hsian ^d,i   Wu, Yen Wen ^d,i   Chu, Pao Hsien ^e,i   Wu, Chih Cheng ^f,i   Hsu, Chih Hsin ^g,i   Wen, Ming Shien ^e,i   Voon, Wen Chol ^h,i   Wang, Chun Chieh ^e   Yeh, San Jou ^e   Lin, Wei Shiang ^a,i   Chan, Kuei Chuan ⁱ   Chang, Heng Chia ⁱ   Chang, Kuan Cheng ⁱ   Chen, Zhih Cherng ⁱ   Chen, Shyh Ming ⁱ   Huang, Jin Long ⁱ   Kuo, Jen yuan ⁱ   Lin, Jiunn Lee ⁱ   Mar, Guang Yuan ⁱ   Shyu, Kou Gi ⁱ   Sung, Shih Hsien ⁱ   Tseng, Wei Kung ⁱ   Wang, Ji Hung ⁱ   Yang, Ning I ⁱ   more..

^a TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^b HUALIEN ARMED FORCES GENERAL HOSPITAL   (Taiwan)

^c TZU CHI UNIVERSITY   (Taiwan)

^d NATIONAL YANG MING UNIVERSITY   (Taiwan)

^e CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^f NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^g NATIONAL CHENG KUNG UNIVERSITY HOSPITAL   (Taiwan)

^h KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

ⁱ Kaohsiung Medical University Hospital ^*

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; ANTIARRHYTHMIC AGENT; ANTICOAGULANT AGENT; ANTITHROMBOCYTIC AGENT; CALCIUM CHANNEL BLOCKING AGENT; DIGITALIS; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; FUROSEMIDE; NITRIC ACID DERIVATIVE; SPIRONOLACTONE;

ADULT; AGED; ARTICLE; BODY MASS; CARDIOVASCULAR MORTALITY; CHINESE; COHORT ANALYSIS; CONTROLLED STUDY; DEMOGRAPHY; DISEASE SEVERITY; FEMALE; FOLLOW UP; HOSPITAL DISCHARGE; HUMAN; JAPANESE (PEOPLE); MAJOR CLINICAL STUDY; MALE; META ANALYSIS (TOPIC); MULTICENTER STUDY; NEW YORK HEART ASSOCIATION CLASS; OBESITY; PRIORITY JOURNAL; PROPORTIONAL HAZARDS MODEL; PROSPECTIVE STUDY; RISK FACTOR; SYSTOLIC HEART FAILURE; TAIWAN; UNDERWEIGHT; CAUSE OF DEATH; COMORBIDITY; FAR EAST; HEART FAILURE; HEART FAILURE, SYSTOLIC; META ANALYSIS; MIDDLE AGED; MORTALITY; PROTECTION; SEVERITY OF ILLNESS INDEX; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; BODY MASS INDEX; CAUSE OF DEATH; COHORT STUDIES; COMORBIDITY; FAR EAST; FEMALE; FOLLOW-UP STUDIES; HEART FAILURE; HEART FAILURE, SYSTOLIC; HUMANS; MALE; MIDDLE AGED; MORTALITY; OBESITY; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; PROTECTIVE FACTORS; SEVERITY OF ILLNESS INDEX; TAIWAN;

EID: 84991735106     PISSN: 00029149     EISSN: 18791913     Source Type: Journal    
DOI: 10.1016/j.amjcard.2016.06.056     Document Type: Article

References (30)

1. 1 Fontaine, K.R., Redden, D.T., Wang, C., Westfall, A.O., Allison, D.B., Years of life lost due to obesity. JAMA 289 (2003), 187–193.
2. 2 Ellis, S.G., Elliott, J., Horrigan, M., Raymond, R.E., Howell, G., Low-normal or excessive body mass index: newly identified and powerful risk factors for death and other complications with percutaneous coronary intervention. Am J Cardiol 78 (1996), 642–646.
3. 3 Oreopoulos, A., McAlister, F.A., Kalantar-Zadeh, K., Padwal, R., Ezekowitz, J.A., Sharma, A.M., Kovesdy, C.P., Fonarow, G.C., Norris, C.M., The relationship between body mass index, treatment, and mortality in patients with established coronary artery disease: a report from approach. Eur Heart J 30 (2009), 2584–2592.
4. 4 Lin, G.M., Li, Y.H., Lin, C.L., Wang, J.H., Han, C.L., Relation of body mass index to mortality among Asian patients with obstructive coronary artery disease during a 10-year follow-up: a report from the ET-CHD registry. Int J Cardiol 168 (2013), 616–620.
5. 5 Horwich, T.B., Fonarow, G.C., Hamilton, M.A., MacLellan, W.R., Woo, M.A., Tillisch, J.H., The relationship between obesity and mortality in patients with heart failure. J Am Coll Cardiol 38 (2001), 789–795.
6. 6 Kenchaiah, S., Pocock, S.J., Wang, D., Finn, P.V., Zornoff, L.A., Skali, H., Pfeffer, M.A., Yusuf, S., Swedberg, K., Michelson, E.L., Granger, C.B., McMurray, J.J., Solomon, S.D., CHARM Investigators. Body mass index and prognosis in patients with chronic heart failure: insights from the Candesartan in Heart failure: Assessment of Reduction in Mortality and morbidity (CHARM) program. Circulation 116 (2007), 627–636.
7. 7 Nochioka, K., Shiba, N., Kohno, H., Miura, M., Shimokawa, H., Both high and low body mass indexes are prognostic risks in Japanese patients with chronic heart failure: implications from the CHART study. J Card Fail 16 (2010), 880–887.
8. 8 Hamaguchi, S., Tsuchihashi-Makaya, M., Kinugawa, S., Goto, D., Yokota, T., Goto, K., Yamada, S., Yokoshiki, H., Takeshita, A., Tsutsui, H., JCARE-CARD Investigators. Body mass index is an independent predictor of long-term outcomes in patients hospitalized with heart failure in Japan. Circ J 74 (2010), 2605–2611.
9. 9 Shah, R., Gayat, E., Januzzi, J.L. Jr., Sato, N., Cohen-Solal, A., diSomma, S., Fairman, E., Harjola, V.P., Ishihara, S., Lassus, J., Maggioni, A., Metra, M., Mueller, C., Mueller, T., Parenica, J., Pascual-Figal, D., Peacock, W.F., Spinar, J., van Kimmenade, R., Mebazaa, A., GREAT (Global Research on Acute Conditions Team) Network. Body mass index and mortality in acutely decompensated heart failure across the world: a global obesity paradox. J Am Coll Cardiol 63 (2014), 778–785.
10. 10 Higgins, J.P., Thompson, S.G., Deeks, J.J., Altman, D.G., Measuring inconsistency in meta-analyses. BMJ 327 (2003), 557–560.
11. 11 Xu, Y., Shi, Y., Zhu, Z., Cui, C., Li, B., Chen, F., Li, D., Chen, S., Guo, Y., Prognosis of patients with heart failure and reduced ejection fraction in China. Exp Ther Med 6 (2013), 1437–1442.
12. 12 Cai, C., Hua, W., Ding, L.G., Wang, J., Chen, K.P., Yang, X.W., Liu, Z.M., Zhang, S., Association of body mass index with cardiac reverse remodeling and long-term outcome in advanced heart failure patients with cardiac resynchronization therapy. Circ J 78 (2014), 2899–2907.
13. 13 Wang, J., Yang, Y.M., Zhu, J., Zhang, H., Shao, X.H., Obesity paradox in patients with atrial fibrillation and heart failure. Int J Cardiol 176 (2014), 1356–1358.
14. 14 Kaneko, H., Suzuki, S., Yajima, J., Oikawa, Y., Sagara, K., Otsuka, T., Matsuno, S., Kano, H., Uejima, T., Koike, A., Nagashima, K., Kirigaya, H., Sawada, H., Aizawa, T., Yamashita, T., Clinical characteristics and long-term clinical outcomes of Japanese heart failure patients with preserved versus reduced left ventricular ejection fraction: a prospective cohort of Shinken Database 2004-2011. J Cardiol 62 (2013), 102–109.
15. 15 Takiguchi, M., Yoshihisa, A., Miura, S., Shimizu, T., Nakamura, Y., Yamauchi, H., Iwaya, S., Owada, T., Miyata, M., Abe, S., Sato, T., Suzuki, S., Suzuki, H., Saitoh, S., Takeishi, Y., Impact of body mass index on mortality in heart failure patients. Eur J Clin Invest 44 (2014), 1197–1205.
16. 16 Kalantar-Zadeh, K., Block, G., Howich, T., Fonarow, G.C., Reverse epidemiology of conventional cardiovascular risk factors in patients with chronic heart failure. J Am Coll Cardiol 43 (2004), 1439–1444.
17. 17 Kalantar-Zadeh, K., Abbott, K.C., Salahudeen, A.K., Kilpatrick, R.D., Horwich, T.B., Survival advantages of obesity in dialysis patients. Am J Clin Nutr 81 (2005), 543–554.
18. 18 Standl, E., Erbach, M., Schnell, O., Defending the con side: obesity paradox does not exist. Diabetes Care 36 (2013), S282–S286.
19. 2 max/kg in obese heart failure patients indicative of cardiac dysfunction?. Int J Cardiol 184 (2015), 755–762.
20. 20 Lin, G.M., Li, Y.H., Liu, P.Y., Wu, C.F., Wang, W.B., Han, C.L., Reverse epidemiology in patients with heart failure: the role of circulatory power and cardiac reserve. Int J Cardiol 188 (2015), 54–55.
21. 21 Tsukinoki, R., Murakami, Y., Huxley, R., Ohkubo, T., Fang, X., Suh, I., Ueshima, H., Lam, T.H., Woodward, M., on behalf of the Asia Pacific Cohort Studies Collaboration. Does body mass index impact on the relationship between systolic blood pressure and cardiovascular disease?: meta-analysis of 419 488 individuals from the Asia Pacific cohort studies collaboration. Stroke 43 (2012), 1478–1483.
22. 22 Everett, B.M., Glynn, R.J., MacFadyen, J.G., Ridker, P.M., Rosuvastatin in the prevention of stroke among men and women with elevated levels of C-reactive protein: Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER). Circulation 121 (2010), 143–150.
23. 23 Willi, C., Bodenmann, P., Ghali, W.A., Faris, P.D., Cornuz, J., Active smoking and the risk of type 2 diabetes: a systematic review and meta-analysis. JAMA 298 (2007), 2654–2664.
24. 24 Chang, C.J., Wu, C.H., Chang, C.S., Yao, W.J., Yang, Y.C., Wu, J.S., Lu, F.H., Low body mass index but high percent body fat in Taiwanese subjects: implications of obesity cutoffs. Int J Obes Relat Metab Disord 27 (2003), 253–259.
25. 25 Wildman, R.P., Muntner, P., Reynolds, K., McGinn, A.P., Rajpathak, S., Wylie-Rosett, J., Sowers, M.R., The obese without cardiometabolic risk factor clustering and the normal weight with cardiometabolic risk factor clustering: prevalence and correlates of 2 phenotypes among the US Population (NHANES 1999-2004). Arch Intern Med 168 (2008), 1617–1624.
26. 26 Florez, H., Castillo-Florez, S., Beyond the obesity paradox in diabetes: fitness, fatness, and mortality. JAMA 308 (2012), 619–620.
27. 27 Zamboni, M., Mazzali, G., Zoico, E., Harris, T.B., Meigs, J.B., Di Francesco, V., Fantin, F., Bissoli, L., Bosello, O., Health consequences of obesity in the elderly. Int J Obes (Lond) 29 (2005), 1011–1029.
28. 28 Lee, K., Metabolically obese but normal weight (MONW) and metabolically healthy but obese (MHO) phenotypes in Koreans: characteristics and health behaviors. Asia Pac J Clin Nutr 18 (2009), 280–284.
29. 29 Li, Y.H., Lin, G.M., Lin, C.L., Wang, J.H., Han, C.L., Relation of body mass index to mortality among patients with percutaneous coronary intervention longer than 5 years follow-up: a meta-analysis. Int J Cardiol 168 (2013), 4315–4318.
30. 30 Wang, C.C., Chen, J.H., Yu, W.C., Cheng, J.J., Yin, W.H., Wu, C.C., Li, A.H., Lin, W.S., Chen, P.S., Ueng, K.C., Huang, J.L., Tsai, F.C., Wang, C.H., Fu, T.C., Liu, M.H., Chen, P.R., Pai, H.Y., Cherng, W.J., 2012 guidelines of the Taiwan Society of Cardiology (TSOC) for the diagnosis and treatment of heart failure. Acta Cardiol Sin 28 (2012), 161–195.