Photodynamic therapy using novel glucose-conjugated chlorin increases apoptosis of cholangiocellular carcinoma in comparison with talaporfin sodium

Anticancer Research

Volumn 36, Issue 9, 2016, Pages 4493-4501

  Murakami, Goushi ^a   Nanashima, Atsushi ^a,b   Nonaka, Takashi ^a   Tominaga, Tetsuro ^a   Wakata, Kouki ^a   Sumida, Yorihisa ^a   Akashi, Haruo ^c   Okazaki, Shigetoshi ^d   Kataoka, Hiromi ^e   Nagayasu, Takeshi ^a  

^a NAGASAKI UNIVERSITY GRADUATE SCHOOL OF BIOMEDICAL SCIENCES   (Japan)

^b UNIVERSITY OF MIYAZAKI   (Japan)

^c OKAYAMA UNIVERSITY OF SCIENCE   (Japan)

^d HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

Author keywords

Apoptosis; Cholangiocellular carcinoma; Glucose conjugated chlorine; Light emitting diode laser; Photodynamic therapy

Indexed keywords

5,10,15,20 TETRAKIS [4 (BETA DEXTRO GLUCOPYRANOSYLTHIO) 2,3,5,6 TETRAFLUOROPHENYL] 2,3 [METHANO(N METHYL)IMINOMETHANO]CHLORIN; DYE; ETHIDIUM HOMODIMER III; HOE 33342; LIPOCORTIN 5; PHOTOSENSITIZING AGENT; TALAPORFIN; UNCLASSIFIED DRUG; CHLORIN; GLUCOSE; PORPHYRIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BAGG ALBINO MOUSE; BILE DUCT CARCINOMA; CANCER CELL LINE; CANCER INHIBITION; CANCER SIZE; CELL DEATH; CONCENTRATION RESPONSE; CONTROLLED STUDY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IC50; IN VITRO STUDY; IN VIVO STUDY; LIGHT EMITTING DIODE; MALE; MOUSE; MTS ASSAY; NONHUMAN; NOZ CELL LINE; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL; TUMOR XENOGRAFT; ANIMAL; BILE DUCT NEOPLASMS; CELL SURVIVAL; CHEMISTRY; CHOLANGIOCARCINOMA; COMPARATIVE STUDY; LASER; NUDE MOUSE; PHOTOCHEMOTHERAPY; PREVALENCE; PROCEDURES; TUMOR CELL LINE; TUNEL ASSAY;

ANIMALS; APOPTOSIS; BILE DUCT NEOPLASMS; CELL LINE, TUMOR; CELL SURVIVAL; CHOLANGIOCARCINOMA; FLOW CYTOMETRY; GLUCOSE; HUMANS; IN SITU NICK-END LABELING; LASERS; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; PORPHYRINS; PREVALENCE;

EID: 84991730369     PISSN: 02507005     EISSN: 17917530     Source Type: Journal    
DOI: 10.21873/anticanres.10995     Document Type: Article

References (33)

1. Miyazaki M, Takada T, Miyakawa S, Tsukada K, Nagino M, Kondo S, Furuse J, Saito H, Tsuyuguchi T, Chijiiwa K, Kimura F, Yoshitomi H, Nozawa S, Yoshida M, Wada K, Amano H and Miura F; Japanese Association of Biliary Surgery; Japanese Society of Hepato-Pancreatic Surgery; Japan Society of Clinical Oncology: Risk factors for biliary tract and ampullary carcinomas and prophylactic surgery for these factors. J Hepatobiliary Pancreat Surg 15: 15-24, 2008.
2. Zhimin G, Noor H, Jian-Bo Z, Lin W and Jha RK: Advances in diagnosis and treatment of hilar cholangiocarcinoma-A review. Med Sci Monit 19: 648-656, 2013.
3. Igami T, Nishio H, Ebata T, Yokoyama Y, Sugawara G, Nimura Y and Nagino M: Surgical treatment of hilar cholangiocarcinoma in the new era: the Nagoya University experience. J Hepatobiliary Pancreat Sci 17: 449-454, 2010.
4. Miyazaki M, Yoshitomi H, Miyakawa S, Uesaka K, Unno M, Endo I, Ota T, Ohtsuka M, Kinoshita H, Shimada K, Shimizu H, Tabata M, Chijiiwa K, Nagino M, Hirano S, Wakai T, Wada K, Isayama H, Okusaka T, Tsuyuguchi T, Fujita N, Furuse J, Yamao K, Murakami K, Yamazaki H, Kijima H, Nakanuma Y, Yoshida M, Takayashiki T and Takada T: Clinical practice guidelines for the management of biliary tract cancers 2015: the II English edition. J Hepatobiliary Pancreat Sci 22: 249-273, 2015.
5. Berr F, Wiedmann M, Tannapfel A, Halm U, Kohlhaw KR, Schmidt F, Wittekind C, Hauss J and Mossner J: Photodynamic therapy for advanced bile duct cancer: evidence for improved palliation and extended survival. Hepatology 31: 291-298, 2000.
6. Ortner ME, Caca K, Berr F, Liebetruth J, Mansmann U, Huster D, Voderholzer W, Schachschal G, Mössner J and Lochs H: Successful photodynamic therapy for nonresectable cholangiocarcinoma: a randomized prospective study. Gastroenterology 125: 1355-1363, 2003.
7. Wiedmann M, Caca K, Berr F, Schiefke I, Tannapfel A, Wittekind C, Mössner J, Hauss J and Witzigmann H: Neoadjuvant photodynamic therapy as a new approach to treating hilar cholangiocarcinoma: a phase II pilot study. Cancer 97: 2783-2790, 2003.
8. Nanashima A, Yamaguchi H, Shibasaki S, Ide N, Sawai T, Tsuji T, Hidaka S, Sumida Y, Nakagoe T and Nagayasu T: Adjuvant photodynamic therapy for bile duct carcinoma after surgery: a preliminary study. J Gastroenterol 39: 1095-1101, 2004.
9. Agostinis P, Berg K, Cengel KA, Foster TH, Girotti AW, Gollnick SO, Hahn SM, Hamblin MR, Juzeniene A, Kessel D, Korbelik M, Moan J, Mroz P, Nowis D, Piette J, Wilson BC and Golab J: Photodynamic therapy of cancer: An update. CA Cancer J Clin 61: 250-281, 2011.
10. Nanashima A and Nagayasu T: Current status of photodynamic therapy in digestive tract carcinoma in Japan. Int J Mol Sci 16: 3434-3440, 2015.
11. Dolmans DE, Fukumura D and Jain RK: Photodynamic therapy for cancer. Nat Rev Cancer 3: 380-387, 2003.
12. Dougherty TJ: Photodynamic therapy (PDT) of malignant tumors. Crit Rev Oncol Hematol 2: 83-116, 1984.
13. Nonaka T, Nanashima A, Nonaka M, Uehara M, Isomoto H, Asahina I and Nagayasu T: Analysis of apoptotic effects induced by photodynamic therapy in a human biliary cancer cell line. Anticancer Res 30: 2113-2118, 2010.
14. Gomer CJ, Rucker N, Ferrario A and Wong S: Properties and applications of photodynamic therapy. Radiat Res 120: 1-18, 1989.
15. Kato H, Furukawa K, Sato M, Okunaka T, Kusunoki Y, Kawahara M, Fukuoka M, Miyazawa T, Yana T, Matsui K, Shiraishi T and Horinouchi H: Phase II clinical study of photodynamic therapy using mono-L-aspartyl chlorin e6 and diode laser for early superficial squamous cell carcinoma of the lung. Lung Cancer 42: 103-111, 2003.
16. Roberts WG, Shiau FY, Nelson JS, Smith KM and Berns MW: In vitro characterization of monoaspartyl chlorin e6 and diaspartyl chlorin e6 for photodynamic therapy. J Natl Cancer Inst 80: 330-336, 1988.
17. Ferrario A, Kessel D and Gomer CJ: Metabolic properties and photosensitizing responsiveness of mono-L-aspartyl chlorin e6 in a mouse tumor model. Cancer Res 52: 2890-2893, 1992.
18. Nonaka T, Nanashima A, Nonaka M, Uehara M, Isomoto H, Nonaka Y and Nagayasu T: Advantages of laserphyrin compared with photofrin in photodynamic therapy for bile duct carcinoma. J Hepatobiliary Pancreat Sci 18: 592-600, 2011.
19. Nonaka Y, Nanashima A, Nonaka T, Uehara M, Isomoto H, Abo T and Nagayasu T: Synergic effect of photodynamic therapy using talaporfin sodium with conventional anticancer chemotherapy for the treatment of bile duct carcinoma. J Surg Res 181: 234-241, 2013.
20. Nanashima A, Isomoto H, Abo T, Nonaka T, Morisaki T, Arai J, Takagi K, Ohnita K, Shoji H, Urabe S, Senoo T, Murakami G and Nagayasu T: How to access photodynamic therapy for bile duct carcinoma. Ann Transl Med 2: 23, 2014.
21. Hayashi N, Kataoka H, Yano S, Tanaka M, Moriwaki K, Akashi H, Suzuki S, Mori Y, Kubota E, Tanida S, Takahashi S and Joh T: A novel photodynamic therapy targeting cancer cells and tumor-associated macrophages. Mol Cancer Ther 14: 452-460, 2015.
22. Narumi A, Tsuji T, Shinohara K, Yamazaki H, Kikuchi M, Kawaguchi S, Mae T, Ikeda A, Sakai Y, Kataoka H, Inoue M, Nomoto A, Kikuchi J and Yano S: Maltotriose-conjugation to a fluorinated chlorin derivative generating a PDT photosensitizer with improved water-solubility. Org Biomol Chem 14: 3608-3613, 2016.
23. Szliszka E, Mazur B, Zydowicz G, Czuba ZP and Król W: TRAIL-induced apoptosis and expression of death receptor TRAIL-R1 and TRAIL-R2 in bladder cancer cells. Folia Histochem Cytobiol 47: 579-585, 2009.
24. Mamoru T, Hiromi K, Motoshi M, Shiho S, Satoru T, Ryoto T, Haruo A, Hiromi O, Shigenobu Y, Akimichi M and Takashi J: Anticancer Effects of Novel Photodynamic Therapy with Glycoconjugated Chlorin for Gastric and Colon Cancer: Anticancer Res 31: 763-770, 2011.
25. Strand DS, Cosgrove ND, Patrie JT, Cox DG, Bauer TW, Adams RB, Mann JA, Sauer BG, Shami VM and Wang AY: ERCPdirected radiofrequency ablation and photodynamic therapy are associated with comparable survival in the treatment of unresectable cholangiocarcinoma. Gastrointest Endosc 80: 794-804, 2014.
26. Horimatsu T, Muto M, Yoda Y, Yano T, Ezoe Y, Miyamoto S and Chiba T: Tissue damage in the canine normal esophagus by photoactivation with talaporfin sodium (laserphyrin): a preclinical study. PLoS One 7: e38308, 2012.
27. Tanaka M, Kataoka H, Yano S, Ohi H, Moriwaki K, Akashi H, Taguchi T, Hayashi N, Hamano S, Mori Y, Kubota E, Tanida S, Joh T: Antitumor effects in gastrointestinal stromal tumors using photodynamic therapy with a novel glucose-conjugated chlorin. Mol Cancer Ther 13: 767-775, 2014.
28. Hirohara S, Obata M, Ogata S, Kajiwara K, Ohtsuki C, Tanihara M and Yano S: Sugar-dependent aggregation of glycoconjugated chlorins and its effect on photocytotoxicity in HeLa cells. J Photochem Photobiol B 43: 56-63, 2006.
29. Vermes I, Haanen C, Steffens-Nakken H, Reutelingsperger C:A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V. J Immunol Methods 17: 39-51, 1995.
30. Overmeyer JH, Kaul A, Johnson EE, Maltese WA: Active ras triggers death in glioblastoma cells through hyperstimulation of macropinocytosis. Mol Cancer Res 6: 965-77, 2008.
31. Hua Jin, Jieyu Dai, Xiaoyan Chen, Jia Liu, Dafang Zhong, Yansong Gu and, Jiang Zheng: Pulmonary Toxicity and Metabolic Activation of Dauricine in CD-1 Mice. The American for Phamecology and Experimental Therapeutics JPET 332: 738-746, 2010
32. Inoue K, Matsuyama H, Fujimoto K, Hirao Y, Watanabe H, Ozono S, Oyama M, Ueno M, Sugimura Y, Shiina H, Mimata H, Azuma H, Nagase Y, Matsubara A, Ito YM and Shuin T: The clinical trial on the safety and effectiveness of the photodynamic diagnosis of non-muscle-invasive bladder cancer using fluorescent light-guided cystoscopy after oral administration of 5-aminolevulinic acid (5-ALA). Photodiagnosis Photodyn Ther 13: 91-96, 2016.
33. Matsumoto J, Tanimura S, Shiragami T and Yasuda M: Watersolubilization of alkyloxo (methoxo) porphyrinatoantimony bromides. Phys Chem Chem Phys 11: 9766-9971, 2009.