-
1
-
-
80053549859
-
Global mesothelioma deaths reported to the World Health Organization between 1994 and 2008
-
V.Delgermaa, K.Takahashi, E.-K.Park, et al. Global mesothelioma deaths reported to the World Health Organization between 1994 and 2008. Bull World Health Organ. 2011;89(10):716–724.
-
(2011)
Bull World Health Organ
, vol.89
, Issue.10
, pp. 716-724
-
-
Delgermaa, V.1
Takahashi, K.2
Park, E.-K.3
-
2
-
-
79955567765
-
Global magnitude of reported and unreported mesothelioma
-
E.-K.Park, K.Takahashi, T.Hoshuyama, et al. Global magnitude of reported and unreported mesothelioma. Environ Health Perspect. 2011;119(4):514–518.
-
(2011)
Environ Health Perspect
, vol.119
, Issue.4
, pp. 514-518
-
-
Park, E.-K.1
Takahashi, K.2
Hoshuyama, T.3
-
3
-
-
84884326313
-
Asbestos exposure during home renovation in New South Wales
-
E.K.Park, D.H.Yates, R.A.Hyland, et al. Asbestos exposure during home renovation in New South Wales. Med J Aust. 2013;199(6):410–413.
-
(2013)
Med J Aust
, vol.199
, Issue.6
, pp. 410-413
-
-
Park, E.K.1
Yates, D.H.2
Hyland, R.A.3
-
4
-
-
84929692733
-
Randomized trials of systemic medically-treated malignant mesothelioma: a systematic review
-
C.Blomberg, J.Nilsson, G.Holgersson, et al. Randomized trials of systemic medically-treated malignant mesothelioma:a systematic review. Anticancer Res. 2015;35(5):2493–2501.
-
(2015)
Anticancer Res
, vol.35
, Issue.5
, pp. 2493-2501
-
-
Blomberg, C.1
Nilsson, J.2
Holgersson, G.3
-
5
-
-
41549143873
-
Review of pemetrexed in combination with cisplatin for the treatment of malignant pleural mesothelioma
-
R.K.Goudar Review of pemetrexed in combination with cisplatin for the treatment of malignant pleural mesothelioma. Ther Clin Risk Manag. 2008;4(1):205–211.
-
(2008)
Ther Clin Risk Manag
, vol.4
, Issue.1
, pp. 205-211
-
-
Goudar, R.K.1
-
6
-
-
84957856107
-
Bevacizumab for newly diagnosed pleural mesothelioma in the Mesothelioma Avastin Cisplatin Pemetrexed Study (MAPS): a randomised, controlled, open-label, phase 3 trial
-
G.Zalcman, J.Mazieres, J.Margery, et al. Bevacizumab for newly diagnosed pleural mesothelioma in the Mesothelioma Avastin Cisplatin Pemetrexed Study (MAPS):a randomised, controlled, open-label, phase 3 trial. Lancet. 2015;6736(15):1–10.
-
(2015)
Lancet
, vol.6736
, Issue.15
, pp. 1-10
-
-
Zalcman, G.1
Mazieres, J.2
Margery, J.3
-
7
-
-
84884703526
-
Tremelimumab for patients with chemotherapy-resistant advanced malignant mesothelioma: an open-label, single-arm, phase 2 trial
-
Oct
-
L.Calabrò, A.Morra, E.Fonsatti, et al. Tremelimumab for patients with chemotherapy-resistant advanced malignant mesothelioma:an open-label, single-arm, phase 2 trial. Lancet Oncol. 2013 Oct;14(11):1104–1111.• Initial results of checkpoint therapy in MM.
-
(2013)
Lancet Oncol
, vol.14
, Issue.11
, pp. 1104-1111
-
-
Calabrò, L.1
Morra, A.2
Fonsatti, E.3
-
8
-
-
84926418972
-
Efficacy and safety of an intensified schedule of tremelimumab for chemotherapy-resistant malignant mesothelioma: an open-label, single-arm, phase 2 study
-
Apr
-
L.Calabrò, A.Morra, E.Fonsatti, et al. Efficacy and safety of an intensified schedule of tremelimumab for chemotherapy-resistant malignant mesothelioma:an open-label, single-arm, phase 2 study. Lancet Respir Med. 2015 Apr;3(4):301–309.• Results of intensified dosage regimen of tremelimumab in MM.
-
(2015)
Lancet Respir Med
, vol.3
, Issue.4
, pp. 301-309
-
-
Calabrò, L.1
Morra, A.2
Fonsatti, E.3
-
9
-
-
79960122931
-
Dual roles of immune cells and their factors in cancer development and progression
-
B.F.Zamarron, W.Chen. Dual roles of immune cells and their factors in cancer development and progression. Int J Biol Sci. 2011;7(5):651–658.
-
(2011)
Int J Biol Sci
, vol.7
, Issue.5
, pp. 651-658
-
-
Zamarron, B.F.1
Chen, W.2
-
10
-
-
84926160709
-
Immune evasion in cancer: mechanistic basis and therapeutic strategies
-
D.S.Vinay, E.P.Ryan, G.Pawelec, et al. Immune evasion in cancer:mechanistic basis and therapeutic strategies. Semin Cancer Biol. 2015;35:S185–98.
-
(2015)
Semin Cancer Biol
, vol.35
, pp. S185-S198
-
-
Vinay, D.S.1
Ryan, E.P.2
Pawelec, G.3
-
11
-
-
77950346282
-
Immunity, inflammation, and cancer
-
S.I.Grivennikov, F.R.Greten, M.Karin. Immunity, inflammation, and cancer. Cell. 2010;140(6):883–899.
-
(2010)
Cell
, vol.140
, Issue.6
, pp. 883-899
-
-
Grivennikov, S.I.1
Greten, F.R.2
Karin, M.3
-
12
-
-
84855338629
-
Regulatory T cells in melanoma: the final hurdle towards effective immunotherapy?
-
J.F.M.Jacobs, S.Nierkens, C.G.Figdor, et al. Regulatory T cells in melanoma:the final hurdle towards effective immunotherapy? Lancet Oncol. 2012;13(1):32–42.
-
(2012)
Lancet Oncol
, vol.13
, Issue.1
, pp. 32-42
-
-
Jacobs, J.F.M.1
Nierkens, S.2
Figdor, C.G.3
-
13
-
-
33645286546
-
Regulatory T cells, tumor immunity and immunotherapy
-
W.Zou. Regulatory T cells, tumor immunity and immunotherapy. Nat Rev Immunol. 2006;6(4):295–307.
-
(2006)
Nat Rev Immunol
, vol.6
, Issue.4
, pp. 295-307
-
-
Zou, W.1
-
14
-
-
0029078313
-
Synergy between T-cell immunity and inhibition of paracrine stimulation causes tumor rejection
-
L.P.Seung, D.Rowley, P.Dubey, et al. Synergy between T-cell immunity and inhibition of paracrine stimulation causes tumor rejection. Proc Natl Acad Sci U S A. 1995;92(14):6254–6258.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, Issue.14
, pp. 6254-6258
-
-
Seung, L.P.1
Rowley, D.2
Dubey, P.3
-
15
-
-
18544364477
-
Potential regulatory function of human dendritic cells expressing indoleamine 2,3-dioxygenase
-
D.H.Munn, M.D.Sharma, J.R.Lee, et al. Potential regulatory function of human dendritic cells expressing indoleamine 2,3-dioxygenase. Science. 2002;297(5588):1867–1870.
-
(2002)
Science
, vol.297
, Issue.5588
, pp. 1867-1870
-
-
Munn, D.H.1
Sharma, M.D.2
Lee, J.R.3
-
16
-
-
0031080901
-
Implications for immunosurveillance of altered HLA class I phenotypes in human tumors
-
F.Garrido, F.Ruiz-Cabello, T.Cabrera, et al. Implications for immunosurveillance of altered HLA class I phenotypes in human tumors. Immunol Today. 1997;18(2):89–95.
-
(1997)
Immunol Today
, vol.18
, Issue.2
, pp. 89-95
-
-
Garrido, F.1
Ruiz-Cabello, F.2
Cabrera, T.3
-
17
-
-
0033120466
-
HLA class I antigen downregulation in human cancers: T-cell immunotherapy revives an old story
-
D.J.Hicklin, F.M.Marincola, S.Ferrone. HLA class I antigen downregulation in human cancers:T-cell immunotherapy revives an old story. Mol Med Today. 1999;5(4):178–186.
-
(1999)
Mol Med Today
, vol.5
, Issue.4
, pp. 178-186
-
-
Hicklin, D.J.1
Marincola, F.M.2
Ferrone, S.3
-
18
-
-
15744372725
-
Role of transforming growth factor beta in human cancer
-
R.L.Elliott. Role of transforming growth factor beta in human cancer. J Clin Oncol. 2005;23(9):2078–2093.
-
(2005)
J Clin Oncol
, vol.23
, Issue.9
, pp. 2078-2093
-
-
Elliott, R.L.1
-
19
-
-
1842788118
-
Tumor necrosis factor receptor 1-mediated signaling is required for skin cancer development induced by NF-kappaB inhibition
-
M.H.Lind, B.Rozell, R.P.Wallin, et al. Tumor necrosis factor receptor 1-mediated signaling is required for skin cancer development induced by NF-kappaB inhibition. Proc Natl Acad Sci U S A. 2004;101(14):4972–4977.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, Issue.14
, pp. 4972-4977
-
-
Lind, M.H.1
Rozell, B.2
Wallin, R.P.3
-
20
-
-
65349156913
-
Costimulatory and coinhibitory receptors in anti-tumor immunity
-
G.Driessens, J.Kline, T.F.Gajewski. Costimulatory and coinhibitory receptors in anti-tumor immunity. Immunol Rev. 2009;229(1):126–144.
-
(2009)
Immunol Rev
, vol.229
, Issue.1
, pp. 126-144
-
-
Driessens, G.1
Kline, J.2
Gajewski, T.F.3
-
21
-
-
84862903106
-
Safety and activity of anti–PD-L1 antibody in patients with advanced cancer
-
Jun
-
W.Hwu, S.L.Topalian, P.Hwu, et al. Safety and activity of anti–PD-L1 antibody in patients with advanced cancer. N Engl J Med. 2012 Jun 28;366(26):2455–2465.
-
(2012)
N Engl J Med
, pp. 2455-2465
-
-
Hwu, W.1
Topalian, S.L.2
Hwu, P.3
-
22
-
-
84938547904
-
Checkpoint blockade for cancer therapy: revitalizing a suppressed immune system
-
Y.Pico de Coaña, A.Choudhury, R.Kiessling Checkpoint blockade for cancer therapy:revitalizing a suppressed immune system. Trends Mol Med. 2015;21(8):482–491.
-
(2015)
Trends Mol Med
, vol.21
, Issue.8
, pp. 482-491
-
-
Pico de Coaña, Y.1
Choudhury, A.2
Kiessling, R.3
-
23
-
-
84958872760
-
Targeting immune checkpoints: new opportunity for mesothelioma treatment?
-
Dec
-
E.Marcq, P.Pauwels, J.P.Van Meerbeeck, et al. Targeting immune checkpoints:new opportunity for mesothelioma treatment? Cancer Treat Rev. 2015 Dec;41(10):914–924.
-
(2015)
Cancer Treat Rev
, vol.41
, Issue.10
, pp. 914-924
-
-
Marcq, E.1
Pauwels, P.2
Van Meerbeeck, J.P.3
-
24
-
-
85016910370
-
Integrating immune checkpoint blockade with anti-neo/mutated antigens reactivity to increase the clinical outcome of immunotherapy
-
G.Parmiani, C.Maccalli, M.Maio. Integrating immune checkpoint blockade with anti-neo/mutated antigens reactivity to increase the clinical outcome of immunotherapy. Vaccines. 2015;3(2):420–428.
-
(2015)
Vaccines
, vol.3
, Issue.2
, pp. 420-428
-
-
Parmiani, G.1
Maccalli, C.2
Maio, M.3
-
25
-
-
84959205080
-
Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations
-
R.Bueno, E.W.Stawiski, L.D.Goldstein, et al. Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations. Nat Genet. 2016;48(4):407–416.•• Details the mutational landscape in MM.
-
(2016)
Nat Genet
, vol.48
, Issue.4
, pp. 407-416
-
-
Bueno, R.1
Stawiski, E.W.2
Goldstein, L.D.3
-
26
-
-
84973497243
-
Immunotherapy in breast cancer
-
F.Marmé. Immunotherapy in breast cancer. Oncol Res Treat. 2016;39(6):335–345.
-
(2016)
Oncol Res Treat
, vol.39
, Issue.6
, pp. 335-345
-
-
Marmé, F.1
-
27
-
-
77955558708
-
CD8+ tumor-infiltrating lymphocytes predict favorable prognosis in malignant pleural mesothelioma after resection
-
Oct
-
N.Yamada, S.Oizumi, E.Kikuchi, et al. CD8+ tumor-infiltrating lymphocytes predict favorable prognosis in malignant pleural mesothelioma after resection. Cancer Immunol Immunother. 2010 Oct;59(10):1543–1549.
-
(2010)
Cancer Immunol Immunother
, vol.59
, Issue.10
, pp. 1543-1549
-
-
Yamada, N.1
Oizumi, S.2
Kikuchi, E.3
-
28
-
-
40949119354
-
Impact of tumor-infiltrating T cells on survival in patients with malignant pleural mesothelioma
-
Apr
-
M.Anraku, K.S.Cunningham, Z.Yun, et al. Impact of tumor-infiltrating T cells on survival in patients with malignant pleural mesothelioma. J Thorac Cardiovasc Surg. 2008 Apr;135(4):823–829.
-
(2008)
J Thorac Cardiovasc Surg
, vol.135
, Issue.4
, pp. 823-829
-
-
Anraku, M.1
Cunningham, K.S.2
Yun, Z.3
-
29
-
-
84937635456
-
Immunotherapy prospects in the treatment of lung cancer and mesothelioma
-
J.G.Aerts, L.A.Lievense, H.C.Hoogsteden, et al. Immunotherapy prospects in the treatment of lung cancer and mesothelioma. Transl Lung Cancer Res. 2014;3(1):34–45.
-
(2014)
Transl Lung Cancer Res
, vol.3
, Issue.1
, pp. 34-45
-
-
Aerts, J.G.1
Lievense, L.A.2
Hoogsteden, H.C.3
-
30
-
-
0032533285
-
Intrapleural administration of interleukin-2 for the treatment of patients with malignant pleural mesothelioma: a phase II study
-
P.Astoul, D.Picat-Joossen, J.R.Viallat, et al. Intrapleural administration of interleukin-2 for the treatment of patients with malignant pleural mesothelioma:a phase II study. Cancer. 1998;83(10):2099–2104.
-
(1998)
Cancer
, vol.83
, Issue.10
, pp. 2099-2104
-
-
Astoul, P.1
Picat-Joossen, D.2
Viallat, J.R.3
-
31
-
-
0035197025
-
A phase II study of combined intravenous and subcutaneous interleukin-2 in malignant pleural mesothelioma
-
C.W.Mulatero, R.T.Penson, D.Papamichael, et al. A phase II study of combined intravenous and subcutaneous interleukin-2 in malignant pleural mesothelioma. Lung Cancer. 2001;31(1):67–72.
-
(2001)
Lung Cancer
, vol.31
, Issue.1
, pp. 67-72
-
-
Mulatero, C.W.1
Penson, R.T.2
Papamichael, D.3
-
32
-
-
33847336995
-
A phase II study of intrapleural immuno-chemotherapy, pleurectomy/decortication, radiotherapy, systemic chemotherapy and long-term sub-cutaneous IL-2 in stage II-III malignant pleural mesothelioma
-
M.Lucchi, A.Chella, F.Melfi, et al. A phase II study of intrapleural immuno-chemotherapy, pleurectomy/decortication, radiotherapy, systemic chemotherapy and long-term sub-cutaneous IL-2 in stage II-III malignant pleural mesothelioma. Eur J Cardio-thoracic Surg. 2007;31(3):529–534.
-
(2007)
Eur J Cardio-thoracic Surg
, vol.31
, Issue.3
, pp. 529-534
-
-
Lucchi, M.1
Chella, A.2
Melfi, F.3
-
33
-
-
0028117013
-
Intrapleural treatment with recombinant gamma-interferon in early stage malignant pleural mesothelioma
-
C.Boutin, E.Nussbaum, I.Monnet, et al. Intrapleural treatment with recombinant gamma-interferon in early stage malignant pleural mesothelioma. Cancer. 1994;74(9):2460–2467.
-
(1994)
Cancer
, vol.74
, Issue.9
, pp. 2460-2467
-
-
Boutin, C.1
Nussbaum, E.2
Monnet, I.3
-
34
-
-
34547692979
-
A phase I clinical trial of single-dose intrapleural IFN-beta gene transfer for malignant pleural mesothelioma and metastatic pleural effusions: high rate of antitumor immune responses
-
D.H.Sterman, A.Recio, R.G.Carroll, et al. A phase I clinical trial of single-dose intrapleural IFN-beta gene transfer for malignant pleural mesothelioma and metastatic pleural effusions:high rate of antitumor immune responses. Clin Cancer Res. 2007;13(15):4456–4466.
-
(2007)
Clin Cancer Res
, vol.13
, Issue.15
, pp. 4456-4466
-
-
Sterman, D.H.1
Recio, A.2
Carroll, R.G.3
-
35
-
-
77950517811
-
A phase I trial of repeated intrapleural adenoviral-mediated interferon-beta gene transfer for mesothelioma and metastatic pleural effusions
-
D.H.Sterman, A.Recio, A.R.Haas, et al. A phase I trial of repeated intrapleural adenoviral-mediated interferon-beta gene transfer for mesothelioma and metastatic pleural effusions. Mol Ther. 2010;18(4):852–860.
-
(2010)
Mol Ther
, vol.18
, Issue.4
, pp. 852-860
-
-
Sterman, D.H.1
Recio, A.2
Haas, A.R.3
-
36
-
-
80455172724
-
A trial of intrapleural adenoviral-mediated interferon-α2b gene transfer for malignant pleural mesothelioma
-
D.H.Sterman, A.Haas, E.Moon, et al. A trial of intrapleural adenoviral-mediated interferon-α2b gene transfer for malignant pleural mesothelioma. Am J Respir Crit Care Med. 2011;184(12):1395–1399.
-
(2011)
Am J Respir Crit Care Med
, vol.184
, Issue.12
, pp. 1395-1399
-
-
Sterman, D.H.1
Haas, A.2
Moon, E.3
-
37
-
-
77953257678
-
Consolidative dendritic cell-based immunotherapy elicits cytotoxicity against malignant mesothelioma
-
J.P.Hegmans, J.D.Veltman, M.E.Lambers, et al. Consolidative dendritic cell-based immunotherapy elicits cytotoxicity against malignant mesothelioma. Am J Respir Crit Care Med. 2010;181(12):1383–1390.
-
(2010)
Am J Respir Crit Care Med
, vol.181
, Issue.12
, pp. 1383-1390
-
-
Hegmans, J.P.1
Veltman, J.D.2
Lambers, M.E.3
-
38
-
-
84991737130
-
Extended tumor control after dendritic cell vaccination with low dose cyclophosphamide as adjuvant treatment in patients with malignant pleural mesothelioma
-
R.Cornelissen, J.P.Hegmans, A.P.Maat, et al. Extended tumor control after dendritic cell vaccination with low dose cyclophosphamide as adjuvant treatment in patients with malignant pleural mesothelioma. Am J Respir Crit Care Med. 2015;14(C):1–40.
-
(2015)
Am J Respir Crit Care Med
, vol.14
, Issue.C
, pp. 1-40
-
-
Cornelissen, R.1
Hegmans, J.P.2
Maat, A.P.3
-
39
-
-
33645993930
-
Recombinant GM-CSF plus autologous tumor cells as a vaccine for patients with mesothelioma
-
A.Powell, J.Creaney, S.Broomfield, et al. Recombinant GM-CSF plus autologous tumor cells as a vaccine for patients with mesothelioma. Lung Cancer. 2006;52(2):189–197.
-
(2006)
Lung Cancer
, vol.52
, Issue.2
, pp. 189-197
-
-
Powell, A.1
Creaney, J.2
Broomfield, S.3
-
40
-
-
77955553483
-
WT1 peptide vaccinations induce CD4 and CD8 T cell immune responses in patients with mesothelioma and non-small cell lung cancer
-
L.M.Krug, T.Dao, A.B.Brown, et al. WT1 peptide vaccinations induce CD4 and CD8 T cell immune responses in patients with mesothelioma and non-small cell lung cancer. Cancer Immunol Immunother. 2010;59(10):1467–1479.
-
(2010)
Cancer Immunol Immunother
, vol.59
, Issue.10
, pp. 1467-1479
-
-
Krug, L.M.1
Dao, T.2
Brown, A.B.3
-
41
-
-
84991659727
-
Randomized phase II study of adjuvant WT1 vaccine (SLS-001) for malignant pleural mesothelioma (MPM) after multimodality therapy
-
M.G.Zauderer, T.Dao, V.W.Rusch, et al. Randomized phase II study of adjuvant WT1 vaccine (SLS-001) for malignant pleural mesothelioma (MPM) after multimodality therapy. J Clin Oncol. 2016;34(suppl):abstr:8519.
-
(2016)
J Clin Oncol
, vol.34
-
-
Zauderer, M.G.1
Dao, T.2
Rusch, V.W.3
-
42
-
-
80051775476
-
T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia
-
M.Kalos, B.L.Levine, D.L.Porter, et al. T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia. Sci Transl Med. 2011;3(95):95ra73.
-
(2011)
Sci Transl Med
, vol.3
, Issue.95
, pp. 95ra73
-
-
Kalos, M.1
Levine, B.L.2
Porter, D.L.3
-
43
-
-
0029947568
-
Enhancement of antitumor immunity by CTLA-4 blockade
-
D.R.Leach, M.F.A.J.Krummel. Enhancement of antitumor immunity by CTLA-4 blockade. Science. 1996;271(5256):1734–1736.
-
(1996)
Science
, vol.271
, Issue.5256
, pp. 1734-1736
-
-
Leach, D.R.1
Krummel, M.F.A.J.2
-
44
-
-
0036569236
-
CTLA-4 suppresses proximal TCR signaling in resting human CD4(+) T cells by inhibiting ZAP-70 Tyr(319) phosphorylation: a potential role for tyrosine phosphatases
-
C.Guntermann, D.R.Alexander. CTLA-4 suppresses proximal TCR signaling in resting human CD4(+) T cells by inhibiting ZAP-70 Tyr(319) phosphorylation:a potential role for tyrosine phosphatases. J Immunol. 2002;168(9):4420–4429.
-
(2002)
J Immunol
, vol.168
, Issue.9
, pp. 4420-4429
-
-
Guntermann, C.1
Alexander, D.R.2
-
45
-
-
79952706673
-
CTLA4 is expressed on mature dendritic cells derived from human monocytes and influences their maturation and antigen presentation
-
X.B.Wang, Z.Z.Fan, D.Anton, et al. CTLA4 is expressed on mature dendritic cells derived from human monocytes and influences their maturation and antigen presentation. BMC Immunol. 2011;12:21.
-
(2011)
BMC Immunol
, vol.12
, pp. 21
-
-
Wang, X.B.1
Fan, Z.Z.2
Anton, D.3
-
46
-
-
38449114545
-
Enhanced engagement of CTLA-4 induces antigen-specific CD4+CD25+Foxp3+ and CD4+CD25- TGF-beta 1+ adaptive regulatory T cells
-
R.Li, N.Perez, S.Karumuthil-Melethil, et al. Enhanced engagement of CTLA-4 induces antigen-specific CD4+CD25+Foxp3+ and CD4+CD25- TGF-beta 1+ adaptive regulatory T cells. J Immunol. 2007;179(8):5191–5203.
-
(2007)
J Immunol
, vol.179
, Issue.8
, pp. 5191-5203
-
-
Li, R.1
Perez, N.2
Karumuthil-Melethil, S.3
-
47
-
-
0036852170
-
CTLA-4-Ig regulates tryptophan catabolism in vivo
-
U.1.Grohmann, C.Orabona, F.Fallarino, et al. CTLA-4-Ig regulates tryptophan catabolism in vivo. Nat Immunol. 2002;3(11):1097–1101.
-
(2002)
Nat Immunol
, vol.3
, Issue.11
, pp. 1097-1101
-
-
Grohmann, U.1
Orabona, C.2
Fallarino, F.3
-
48
-
-
84896523643
-
Ipilimumab treatment results in an early decrease in the frequency of circulating granulocytic myeloid-derived suppressor cells as well as their Arginase1 production
-
Y.Pico de Coaña, I.Poschke, G.Gentilcore, et al. Ipilimumab treatment results in an early decrease in the frequency of circulating granulocytic myeloid-derived suppressor cells as well as their Arginase1 production. Cancer Immunol Res. 2013;1(3):158–162.
-
(2013)
Cancer Immunol Res
, vol.1
, Issue.3
, pp. 158-162
-
-
Pico de Coaña, Y.1
Poschke, I.2
Gentilcore, G.3
-
49
-
-
84894639687
-
Immune monitoring of the circulation and the tumor microenvironment in patients with regionally advanced melanoma receiving neoadjuvant ipilimumab
-
A.Tarhini, H.Edington, L.H.Butterfield, et al. Immune monitoring of the circulation and the tumor microenvironment in patients with regionally advanced melanoma receiving neoadjuvant ipilimumab. PLoS One. 2014;9(2):e87705.
-
(2014)
PLoS One
, vol.9
, Issue.2
, pp. e87705
-
-
Tarhini, A.1
Edington, H.2
Butterfield, L.H.3
-
50
-
-
84862882003
-
Tumor immunotherapy directed at PD-1
-
Jun
-
A.Ribas. Tumor immunotherapy directed at PD-1. N Engl J Med. 2012 Jun 28;366(26):2517–2519.
-
(2012)
N Engl J Med
, vol.366
, Issue.26
, pp. 2517-2519
-
-
Ribas, A.1
-
51
-
-
24944459890
-
Autoimmunity correlates with tumor regression in patients with metastatic melanoma treated with anti-cytotoxic T-lymphocyte antigen-4
-
P.Attia, G.Q.Phan, A.Maker, et al. Autoimmunity correlates with tumor regression in patients with metastatic melanoma treated with anti-cytotoxic T-lymphocyte antigen-4. J Clin Oncol. 2005;23(25):6043–6053.
-
(2005)
J Clin Oncol
, vol.23
, Issue.25
, pp. 6043-6053
-
-
Attia, P.1
Phan, G.Q.2
Maker, A.3
-
52
-
-
79959772576
-
Ipilimumab plus dacarbazine for previously untreated metastatic melanoma
-
C.Robert, L.Thomas, I.Bondarenko, et al. Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. N Engl J Med. 2011;364(26):2517–2526.
-
(2011)
N Engl J Med
, vol.364
, Issue.26
, pp. 2517-2526
-
-
Robert, C.1
Thomas, L.2
Bondarenko, I.3
-
53
-
-
84991693168
-
Tremelimumab as second- or third-line treatment of unresectable malignant mesothelioma (MM): results from the global, double-blind, placebo-controlled DETERMINE study
-
H.L.Kindler, A.Scherpereel, L.Calabrò, et al. Tremelimumab as second- or third-line treatment of unresectable malignant mesothelioma (MM):results from the global, double-blind, placebo-controlled DETERMINE study. J Clin Oncol. 2016;34(suppl):abstr8502.•• Large trial of tremelimumab in MM-negative study.
-
(2016)
J Clin Oncol
, vol.34
, pp. abstr8502
-
-
Kindler, H.L.1
Scherpereel, A.2
Calabrò, L.3
-
54
-
-
0030005099
-
Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes
-
Y.Agata, A.Kawasaki, H.Nishimura, et al. Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes. Int Immunol. 1996;8(5):765–772.
-
(1996)
Int Immunol
, vol.8
, Issue.5
, pp. 765-772
-
-
Agata, Y.1
Kawasaki, A.2
Nishimura, H.3
-
55
-
-
34547794178
-
PD-1 and PD-1 ligands: from discovery to clinical application
-
T.Okazaki, T.Honjo. PD-1 and PD-1 ligands:from discovery to clinical application. Int Immunol. 2007;19(7):813–824.
-
(2007)
Int Immunol
, vol.19
, Issue.7
, pp. 813-824
-
-
Okazaki, T.1
Honjo, T.2
-
56
-
-
18544380239
-
Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion
-
H.Dong, S.E.Strome, D.R.Salomao, et al. Tumor-associated B7-H1 promotes T-cell apoptosis:a potential mechanism of immune evasion. Nat Med. 2002;8(8):739–800.
-
(2002)
Nat Med
, vol.8
, Issue.8
, pp. 739-800
-
-
Dong, H.1
Strome, S.E.2
Salomao, D.R.3
-
57
-
-
0037152153
-
Differential expression of PD-L1 and PD-L2, ligands for an inhibitory receptor PD-1, in the cells of lymphohematopoietic tissues
-
M.Ishida, Y.Iwai, Y.Tanaka, et al. Differential expression of PD-L1 and PD-L2, ligands for an inhibitory receptor PD-1, in the cells of lymphohematopoietic tissues. Immunol Lett. 2002;84(1):57–62.
-
(2002)
Immunol Lett
, vol.84
, Issue.1
, pp. 57-62
-
-
Ishida, M.1
Iwai, Y.2
Tanaka, Y.3
-
58
-
-
33645736792
-
Tumor B7-H1 is associated with poor prognosis in renal cell carcinoma patients with long-term follow-up
-
R.H.Thompson, S.M.Kuntz, B.C.Leibovich, et al. Tumor B7-H1 is associated with poor prognosis in renal cell carcinoma patients with long-term follow-up. Cancer Res. 2006;66(7):3381–3385.
-
(2006)
Cancer Res
, vol.66
, Issue.7
, pp. 3381-3385
-
-
Thompson, R.H.1
Kuntz, S.M.2
Leibovich, B.C.3
-
59
-
-
84925004185
-
Analysis of expression of programmed cell death 1 ligand 1 (PD-L1) in malignant pleural mesothelioma (MPM)
-
Jan
-
S.Cedrés, S.Ponce-Aix, J.Zugazagoitia, et al. Analysis of expression of programmed cell death 1 ligand 1 (PD-L1) in malignant pleural mesothelioma (MPM). PLoS One. 2015 Jan;10(3):e0121071.• Initial report of PD-L1 expression in MM.
-
(2015)
PLoS One
, vol.10
, Issue.3
, pp. e0121071
-
-
Cedrés, S.1
Ponce-Aix, S.2
Zugazagoitia, J.3
-
60
-
-
84902522051
-
B7-H1 expression in malignant pleural mesothelioma is associated with sarcomatoid histology and poor prognosis
-
A.S.Mansfield, A.C.Roden, T.Peikert, et al. B7-H1 expression in malignant pleural mesothelioma is associated with sarcomatoid histology and poor prognosis. J Thorac Oncol. 2014;9(7):1036–1040.• Initial report of PD-L1 in MM.
-
(2014)
J Thorac Oncol
, vol.9
, Issue.7
, pp. 1036-1040
-
-
Mansfield, A.S.1
Roden, A.C.2
Peikert, T.3
-
61
-
-
84898973055
-
Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab
-
S.L.Topalian, M.Sznol, D.F.McDermott, et al. Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab. J Clin Oncol. 2014;32(10):1020–1030.
-
(2014)
J Clin Oncol
, vol.32
, Issue.10
, pp. 1020-1030
-
-
Topalian, S.L.1
Sznol, M.2
McDermott, D.F.3
-
62
-
-
84920956735
-
Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients
-
Nov
-
R.S.Herbst, J.-C.Soria, M.Kowanetz, et al. Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients. Nature. 2014 Nov 26;515(7528):563–567.
-
(2014)
Nature
, vol.515
, Issue.7528
, pp. 563-567
-
-
Herbst, R.S.1
Soria, J.-C.2
Kowanetz, M.3
-
63
-
-
84862903106
-
Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
-
J.R.Brahmer, S.S.Tykodi, L.Q.M.Chow, et al. Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N Engl J Med. 2012;366(26):2455–2465.
-
(2012)
N Engl J Med
, vol.366
, Issue.26
, pp. 2455-2465
-
-
Brahmer, J.R.1
Tykodi, S.S.2
Chow, L.Q.M.3
-
64
-
-
84872514622
-
Durable cancer regression off-treatment and effective reinduction therapy with an anti-PD-1 antibody
-
E.J.Lipson, W.H.Sharfman, C.G.Drake, et al. Durable cancer regression off-treatment and effective reinduction therapy with an anti-PD-1 antibody. Clin Cancer Res. 2013;19(2):462–468.
-
(2013)
Clin Cancer Res
, vol.19
, Issue.2
, pp. 462-468
-
-
Lipson, E.J.1
Sharfman, W.H.2
Drake, C.G.3
-
65
-
-
84879759020
-
Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma
-
O.Hamid, C.Robert, A.Daud, et al. Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma. N Engl J Med. 2013;369(2):134–144.
-
(2013)
N Engl J Med
, vol.369
, Issue.2
, pp. 134-144
-
-
Hamid, O.1
Robert, C.2
Daud, A.3
-
66
-
-
84991572619
-
-
Alley EW, Molife RL, Santoro A, et al. Clinical safety and efficacy of pembrolizumab (MK-3475) in patients with malignant pleural mesothelioma:Preliminary results from KEYNOTE-028 [Abstract]. In:Proceedings of the 106th Annual Meeting of the American Association for Cancer Research; 2015 Apr 18–22. Philadelphia (PA):AACR; 2015. Abstract nr CT103. (Results of anti PD-1 therapy in MM)• Results of anti-PD-1 therapy in MM.
-
(2015)
-
-
-
67
-
-
84991688228
-
-
Quispel-Janssen J, Zimmerman M, Buikhuisen W, et al. Nivolumab in malignant pleural mesothelioma (NIVOMES):An interim analysis [Abstract]. In:Proceedings of the 13th International Conference of the International Mesothelioma Interest Group; 2016 May 1–4. Birmingham:IMIG; 2016. Abstract nr 284.
-
(2016)
-
-
-
68
-
-
84991693144
-
Avelumab (MSB0010718C; anti-PD-L1) in patients with advanced unresectable mesothelioma from the JAVELIN solid tumor phase Ib trial: safety, clinical activity, and PD-L1 expression
-
R.Hassan, A.Thomas, M.R.Patel, et al. Avelumab (MSB0010718C; anti-PD-L1) in patients with advanced unresectable mesothelioma from the JAVELIN solid tumor phase Ib trial:safety, clinical activity, and PD-L1 expression. J Clin Oncol. 2016;34(suppl):abstr8503.• Initial results of anti-PD-L1 therapy in MM.
-
(2016)
J Clin Oncol
, vol.34
, pp. abstr8503
-
-
Hassan, R.1
Thomas, A.2
Patel, M.R.3
-
69
-
-
84864886189
-
CTLA-4 blockade expands infiltrating T cells and inhibits cancer cell repopulation during the intervals of chemotherapy in murine mesothelioma
-
L.Wu, Z.Yun, T.Tagawa, et al. CTLA-4 blockade expands infiltrating T cells and inhibits cancer cell repopulation during the intervals of chemotherapy in murine mesothelioma. Mol Cancer Ther. 2012;11(8):1809–1819.
-
(2012)
Mol Cancer Ther
, vol.11
, Issue.8
, pp. 1809-1819
-
-
Wu, L.1
Yun, Z.2
Tagawa, T.3
-
70
-
-
84991688210
-
Biomarkers associated with checkpoint inhibitors
-
G.Manson, J.Norwood, A.Marabelle, et al. Biomarkers associated with checkpoint inhibitors. Ann Oncol. 2016;33:1–8.
-
(2016)
Ann Oncol
, vol.33
, pp. 1-8
-
-
Manson, G.1
Norwood, J.2
Marabelle, A.3
-
71
-
-
84929481480
-
Pembrolizumab for the treatment of non-small-cell lung cancer
-
May
-
E.B.Garon, N.A.Rizvi, R.Hui, et al. Pembrolizumab for the treatment of non-small-cell lung cancer. N Engl J Med. 2015 May 21;372(21):2018–2028.
-
(2015)
N Engl J Med
, vol.372
, Issue.21
, pp. 2018-2028
-
-
Garon, E.B.1
Rizvi, N.A.2
Hui, R.3
-
72
-
-
84939227614
-
Differential activity of nivolumab, pembrolizumab and MPDL3280A according to the tumor expression of programmed death-ligand-1 (PD-L1): sensitivity analysis of trials in melanoma, lung and genitourinary cancers
-
L.Carbognin, S.Pilotto, M.Milella, et al. Differential activity of nivolumab, pembrolizumab and MPDL3280A according to the tumor expression of programmed death-ligand-1 (PD-L1):sensitivity analysis of trials in melanoma, lung and genitourinary cancers. PLoS One. 2015;10(6):e01300142.
-
(2015)
PLoS One
, vol.10
, Issue.6
, pp. e01300142
-
-
Carbognin, L.1
Pilotto, S.2
Milella, M.3
-
73
-
-
84925222119
-
Nivolumab in previously untreated melanoma without BRAF mutation
-
C.Robert, G.V.Long, B.Brady, et al. Nivolumab in previously untreated melanoma without BRAF mutation. N Engl J Med. 2015;372(4):320–330.
-
(2015)
N Engl J Med
, vol.372
, Issue.4
, pp. 320-330
-
-
Robert, C.1
Long, G.V.2
Brady, B.3
-
74
-
-
84929481481
-
Pembrolizumab versus ipilimumab in advanced melanoma
-
C.Robert, J.Schachter, G.V.Long, et al. Pembrolizumab versus ipilimumab in advanced melanoma. N Engl J Med. 2015;372(26):2521–2532.
-
(2015)
N Engl J Med
, vol.372
, Issue.26
, pp. 2521-2532
-
-
Robert, C.1
Schachter, J.2
Long, G.V.3
-
75
-
-
84858766182
-
The blockade of immune checkpoints in cancer immunotherapy
-
D.M.Pardoll. The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer. 2012;12(4):252–264.
-
(2012)
Nat Rev Cancer
, vol.12
, Issue.4
, pp. 252-264
-
-
Pardoll, D.M.1
-
76
-
-
84925373898
-
Prognostic and predictive markers for the new immunotherapies
-
K.M.Mahoney, M.B.Atkins. Prognostic and predictive markers for the new immunotherapies. Oncology. 2014;28(Suppl 3):39–48.
-
(2014)
Oncology
, vol.28
, pp. 39-48
-
-
Mahoney, K.M.1
Atkins, M.B.2
-
77
-
-
84936147067
-
Combined nivolumab and ipilimumab or monotherapy in untreated melanoma
-
J.Larkin, V.Chiarion-Sileni, R.Gonzalez, et al. Combined nivolumab and ipilimumab or monotherapy in untreated melanoma. N Engl J Med. 2015;373(1):23–34.
-
(2015)
N Engl J Med
, vol.373
, Issue.1
, pp. 23-34
-
-
Larkin, J.1
Chiarion-Sileni, V.2
Gonzalez, R.3
-
78
-
-
84939150439
-
Expanded cohort results from CheckMate 016: a phase I study of nivolumab in combination with ipilimumab in metastatic renal cell carcinoma (mRCC)
-
H.J.Hammers, E.R.Plimack, B.I.Rini, et al. Expanded cohort results from CheckMate 016:a phase I study of nivolumab in combination with ipilimumab in metastatic renal cell carcinoma (mRCC). J Clin Oncol. 2015;33(suppl); abstr 4516.
-
(2015)
J Clin Oncol
, vol.33
, pp. abstr 4516
-
-
Hammers, H.J.1
Plimack, E.R.2
Rini, B.I.3
-
79
-
-
84951127493
-
Safety and efficacy of first-line nivolumab (NIVO; anti-programmed death-1 [PD-1]) and ipilimumab in non-small cell lung cancer (NSCLC)
-
N.A.Rizvi, S.N.Gettinger, J.W.Goldman, et al. Safety and efficacy of first-line nivolumab (NIVO; anti-programmed death-1 [PD-1]) and ipilimumab in non-small cell lung cancer (NSCLC). J Thorac Oncol. 2015;10(suppl2):S176.
-
(2015)
J Thorac Oncol
, vol.10
, pp. S176
-
-
Rizvi, N.A.1
Gettinger, S.N.2
Goldman, J.W.3
-
80
-
-
84860436621
-
Combined immunotherapy with granulocyte-macrophage colony-stimulating factor-transduced allogeneic prostate cancer cells and ipilimumab in patients with metastatic castration-resistant prostate cancer: a phase 1 dose-escalation trial
-
A.J.Van den Eertwegh, J.Versluis, H.P.van den Berg, et al. Combined immunotherapy with granulocyte-macrophage colony-stimulating factor-transduced allogeneic prostate cancer cells and ipilimumab in patients with metastatic castration-resistant prostate cancer:a phase 1 dose-escalation trial. Lancet Oncol. 2012;13(5):509–517.
-
(2012)
Lancet Oncol
, vol.13
, Issue.5
, pp. 509-517
-
-
Van den Eertwegh, A.J.1
Versluis, J.2
van den Berg, H.P.3
-
81
-
-
84860455345
-
Ipilimumab and a poxviral vaccine targeting prostate-specific antigen in metastatic castration-resistant prostate cancer: a phase 1 dose-escalation trial
-
R.A.Madan, M.Mohebtash, P.M.Arlen, et al. Ipilimumab and a poxviral vaccine targeting prostate-specific antigen in metastatic castration-resistant prostate cancer:a phase 1 dose-escalation trial. Lancet Oncol. 2012;13(5):501–508.
-
(2012)
Lancet Oncol
, vol.13
, Issue.5
, pp. 501-508
-
-
Madan, R.A.1
Mohebtash, M.2
Arlen, P.M.3
-
82
-
-
84883207410
-
Evaluation of ipilimumab in combination with allogeneic pancreatic tumor cells transfected with a GM-CSF gene in previously treated pancreatic cancer
-
D.T.Le, E.Lutz, J.N.Uram, et al. Evaluation of ipilimumab in combination with allogeneic pancreatic tumor cells transfected with a GM-CSF gene in previously treated pancreatic cancer. J Immunother. 2013;36(7):382–389.
-
(2013)
J Immunother
, vol.36
, Issue.7
, pp. 382-389
-
-
Le, D.T.1
Lutz, E.2
Uram, J.N.3
-
83
-
-
84880796356
-
The peripheral myeloid expansion driven by murine cancer progression is reversed by radiation therapy of the tumor
-
M.R.Crittenden, T.Savage, B.Cottam, et al. The peripheral myeloid expansion driven by murine cancer progression is reversed by radiation therapy of the tumor. PLoS One. 2013;8(7):e69527.
-
(2013)
PLoS One
, vol.8
, Issue.7
, pp. e69527
-
-
Crittenden, M.R.1
Savage, T.2
Cottam, B.3
-
84
-
-
84870982567
-
Chemotherapy broadens the range of tumor antigens seen by cytotoxic CD8(+) T cells in vivo
-
C.Jackaman, D.Majewski, S.A.Fox, et al. Chemotherapy broadens the range of tumor antigens seen by cytotoxic CD8(+) T cells in vivo. Cancer Immunol Immmunother. 2012;61(12):2343.
-
(2012)
Cancer Immunol Immmunother
, vol.61
, Issue.12
, pp. 2343
-
-
Jackaman, C.1
Majewski, D.2
Fox, S.A.3
-
85
-
-
69949085196
-
Fractionated but not single-dose radiotherapy induces an immune-mediated abscopal effect when combined with anti-CTLA-4 antibody
-
M.Z.Dewan, A.E.Galloway, N.Kawashima, et al. Fractionated but not single-dose radiotherapy induces an immune-mediated abscopal effect when combined with anti-CTLA-4 antibody. Clin Cancer Res. 2009;15(17):5379–5388.
-
(2009)
Clin Cancer Res
, vol.15
, Issue.17
, pp. 5379-5388
-
-
Dewan, M.Z.1
Galloway, A.E.2
Kawashima, N.3
-
86
-
-
78049479930
-
Chemotherapy delivered after viral immunogene therapy augments antitumor efficacy via multiple immune-mediated mechanisms
-
Z.G.Fridlender, J.Sun, S.Singhal, et al. Chemotherapy delivered after viral immunogene therapy augments antitumor efficacy via multiple immune-mediated mechanisms. Mol Ther. 2010;18(11):1947–1959.
-
(2010)
Mol Ther
, vol.18
, Issue.11
, pp. 1947-1959
-
-
Fridlender, Z.G.1
Sun, J.2
Singhal, S.3
-
87
-
-
77953496545
-
Low-dose cyclophosphamide synergizes with dendritic cell-based immunotherapy in antitumor activitys
-
J.D.Veltman, M.E.H.Lambers, M.Van Nimwegen, et al. Low-dose cyclophosphamide synergizes with dendritic cell-based immunotherapy in antitumor activitys. J Biomed Biotechnol. 2010;2010:798467.
-
(2010)
J Biomed Biotechnol
, vol.2010
, pp. 798467
-
-
Veltman, J.D.1
Lambers, M.E.H.2
Van Nimwegen, M.3
-
88
-
-
84876522514
-
Synergistic effect of CTLA-4 blockade and cancer chemotherapy in the induction of anti-tumor immunity
-
W.J.Lesterhuis, J.Salmons, A.K.Nowak, et al. Synergistic effect of CTLA-4 blockade and cancer chemotherapy in the induction of anti-tumor immunity. PLoS One. 2013;8(4):1–8.
-
(2013)
PLoS One
, vol.8
, Issue.4
, pp. 1-8
-
-
Lesterhuis, W.J.1
Salmons, J.2
Nowak, A.K.3
-
89
-
-
84949936992
-
A phase 1b clinical trial of the CD40-activating antibody CP-870,893 in combination with cisplatin and pemetrexed in malignant pleural mesothelioma
-
A.K.Nowak, A.M.Cook, A.M.McDonnell, et al. A phase 1b clinical trial of the CD40-activating antibody CP-870,893 in combination with cisplatin and pemetrexed in malignant pleural mesothelioma. Ann Oncol. 2015;26(12):2483–2490.
-
(2015)
Ann Oncol
, vol.26
, Issue.12
, pp. 2483-2490
-
-
Nowak, A.K.1
Cook, A.M.2
McDonnell, A.M.3
-
90
-
-
84899742483
-
Immunotherapy for malignant pleural mesothelioma current status and future prospects
-
R.M.Wong, I.Ianculescu, S.Sharma, et al. Immunotherapy for malignant pleural mesothelioma current status and future prospects. Am J Respir Cell Mol Biol. 2014;50(5):870–875.
-
(2014)
Am J Respir Cell Mol Biol
, vol.50
, Issue.5
, pp. 870-875
-
-
Wong, R.M.1
Ianculescu, I.2
Sharma, S.3
-
91
-
-
10744230328
-
Immuno-gene therapy with interferon-β before surgical debulking delays recurrence and improves survival in a murine model of malignant mesothelioma
-
R.J.Kruklitis, S.Singhal, P.Delong, et al. Immuno-gene therapy with interferon-β before surgical debulking delays recurrence and improves survival in a murine model of malignant mesothelioma. J Thorac Cardiovasc Surg. 2004;127(1):123–130.
-
(2004)
J Thorac Cardiovasc Surg
, vol.127
, Issue.1
, pp. 123-130
-
-
Kruklitis, R.J.1
Singhal, S.2
Delong, P.3
-
92
-
-
0034868843
-
The immune anti-tumor effects of GM-CSF and B7-1 gene transfection are enhanced by surgical debulking of tumor
-
S.Mukherjee, D.Nelson, S.Loh, et al. The immune anti-tumor effects of GM-CSF and B7-1 gene transfection are enhanced by surgical debulking of tumor. Cancer Gene Ther. 2001;8(8):580–588.
-
(2001)
Cancer Gene Ther
, vol.8
, Issue.8
, pp. 580-588
-
-
Mukherjee, S.1
Nelson, D.2
Loh, S.3
|