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Volumn 55, Issue 10, 2016, Pages 1726-1735

Non-vitamin K antagonist oral anticoagulants and antiphospholipid syndrome

Author keywords

Anti phospholipid antibodies; Anti phospholipid syndrome; Apixaban; Dabigatran; Rivaroxaban; Thrombosis

Indexed keywords

APIXABAN; DABIGATRAN ETEXILATE; EDOXABAN; LUPUS ANTICOAGULANT; RIVAROXABAN; ANTICOAGULANT AGENT; ANTITHROMBIN; BLOOD CLOTTING FACTOR 10A INHIBITOR; VITAMIN K GROUP;

EID: 84991058634     PISSN: 14620324     EISSN: 14620332     Source Type: Journal    
DOI: 10.1093/rheumatology/kev445     Document Type: Review
Times cited : (28)

References (68)
  • 1
    • 33344458573 scopus 로고    scopus 로고
    • International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS)
    • Miyakis S, Lockshin MD, Atsumi T et al. International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J Thromb Haemost 2006;4:295-306.
    • (2006) J Thromb Haemost , vol.4 , pp. 295-306
    • Miyakis, S.1    Lockshin, M.D.2    Atsumi, T.3
  • 3
    • 84856802635 scopus 로고    scopus 로고
    • Antithrombotic therapy for VTE disease: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
    • Kearon C, Akl EA, Comerota AJ et al. Antithrombotic therapy for VTE disease: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest 2012;141:e419S-94S.
    • (2012) Chest , vol.141 , pp. e419S-e4194S
    • Kearon, C.1    Akl, E.A.2    Comerota, A.J.3
  • 4
    • 84896544929 scopus 로고    scopus 로고
    • 14th International Congress on Antiphospholipid Antibodies: task force report on antiphospholipid syndrome treatment trends
    • Erkan D, Aguiar CL, Andrade D et al. 14th International Congress on Antiphospholipid Antibodies: task force report on antiphospholipid syndrome treatment trends. Autoimmun Rev 2014;13:685-96.
    • (2014) Autoimmun Rev , vol.13 , pp. 685-696
    • Erkan, D.1    Aguiar, C.L.2    Andrade, D.3
  • 5
    • 4644224760 scopus 로고    scopus 로고
    • Boehringer Ingelheim International GmBH (1 September 2015, date last accessed).
    • Pradaxa 150mg hard capsules. Summary of Product Characteristics (SPC), EU. Boehringer Ingelheim International GmBH, 2012. www.emc.medicines.org.uk (1 September 2015, date last accessed).
    • (2012) Summary of Product Characteristics (SPC), EU
  • 6
    • 4644224760 scopus 로고    scopus 로고
    • Bayer HealthCare AG (1 September 2015, date last accessed).
    • Xarelto 20mg film-coated tablets. Summary of Product Characteristics (SPC), EU. Bayer HealthCare AG, 2012. www.emc.medicines.org.uk (1 September 2015, date last accessed).
    • (2012) Summary of Product Characteristics (SPC), EU
  • 7
    • 84880327613 scopus 로고    scopus 로고
    • Oral apixaban for the treatment of acute venous thromboembolism
    • Agnelli G, Buller HR, Cohen A et al. Oral apixaban for the treatment of acute venous thromboembolism. N Engl J Med 2013;369:799-808.
    • (2013) N Engl J Med , vol.369 , pp. 799-808
    • Agnelli, G.1    Buller, H.R.2    Cohen, A.3
  • 8
    • 78650619315 scopus 로고    scopus 로고
    • Oral rivaroxaban for symptomatic venous thromboembolism
    • Bauersachs R, Berkowitz SD, Brenner B et al. Oral rivaroxaban for symptomatic venous thromboembolism. N Engl J Med 2010;363:2499-510.
    • (2010) N Engl J Med , vol.363 , pp. 2499-2510
    • Bauersachs, R.1    Berkowitz, S.D.2    Brenner, B.3
  • 10
    • 84906096026 scopus 로고    scopus 로고
    • NICE (1 September 2015, date last accessed).
    • NICE technology appraisal guidance 245. Venous thromboembolism-apixaban (hip and knee surgery). NICE, 2012. www.nice.org.uk/TA (1 September 2015, date last accessed).
    • (2012) Venous thromboembolism-apixaban (hip and knee surgery)
  • 11
    • 71849117615 scopus 로고    scopus 로고
    • Dabigatran versus warfarin in the treatment of acute venous thromboembolism
    • Schulman S, Kearon C, Kakkar AK et al. Dabigatran versus warfarin in the treatment of acute venous thromboembolism. N Engl J Med 2009;361:2342-52.
    • (2009) N Engl J Med , vol.361 , pp. 2342-2352
    • Schulman, S.1    Kearon, C.2    Kakkar, A.K.3
  • 12
    • 84991077478 scopus 로고    scopus 로고
    • London: European Medicines Agency, (1 September 2015, date last accessed)
    • Committee for Medicinal Products for Human Use (CHMP), European Medicines Agency. Pradaxa; EMEA/H/C/000829/II/0032. London: European Medicines Agency, 2012. http://www.ema.europa.eu (1 September 2015, date last accessed).
    • (2012) Pradaxa; EMEA/H/C/000829/II/0032
  • 13
    • 84991084525 scopus 로고    scopus 로고
    • EMEA/H/C/000944/X/0010 (1 September 2015, date last accessed).
    • Committee for Medicinal Products for Human Use (CHMP), European Medicines Agency. Xarelto; EMEA/H/C/000944/X/0010, 2011. http://www.ema.europa.eu (1 September 2015, date last accessed).
    • (2011) Xarelto
  • 14
    • 84991084524 scopus 로고    scopus 로고
    • London: European Medicines Agency, (1 September 2015, date last accessed)
    • Committee for Medicinal Products for Human Use (CHMP), European Medicines Agency. Eliquis; EMA/439534/2014. London: European Medicines Agency, 2014. http://www. ema.europa.eu (1 September 2015, date last accessed).
    • (2014) Eliquis; EMA/439534/2014
  • 15
    • 84859385808 scopus 로고    scopus 로고
    • Oral rivaroxaban for the treatment of symptomatic pulmonary embolism
    • Büller HR, Prins MH, Lensin AWA et al. Oral rivaroxaban for the treatment of symptomatic pulmonary embolism. N Engl J Med 2012;366:1287-97.
    • (2012) N Engl J Med , vol.366 , pp. 1287-1297
    • Büller, H.R.1    Prins, M.H.2    Lensin, A.W.A.3
  • 16
    • 84960434570 scopus 로고    scopus 로고
    • Thrombotic events in patients with antiphospholipid syndrome treated with rivaroxaban: a series of eight cases
    • Advance Access published 30 July 2015
    • Signorelli F, Nogueira F, Domingues V, Mariz HA, Levy RA. Thrombotic events in patients with antiphospholipid syndrome treated with rivaroxaban: a series of eight cases. Clin Rheumatol 2015; Advance Access published 30 July 2015, doi: 10.1007/s10067-015-3030-y.
    • (2015) Clin Rheumatol
    • Signorelli, F.1    Nogueira, F.2    Domingues, V.3    Mariz, H.A.4    Levy, R.A.5
  • 17
    • 84929471149 scopus 로고    scopus 로고
    • Rivaroxaban use in patients with antiphospholipid syndrome and previous venous thromboembolism
    • Sciascia S, Breen K, Hunt BJ. Rivaroxaban use in patients with antiphospholipid syndrome and previous venous thromboembolism. Blood Coagul Fibrinolysis 2015;26:476-7.
    • (2015) Blood Coagul Fibrinolysis , vol.26 , pp. 476-477
    • Sciascia, S.1    Breen, K.2    Hunt, B.J.3
  • 18
    • 84907994966 scopus 로고    scopus 로고
    • New oral anticoagulants may not be effective to prevent venous thromboembolism in patients with antiphospholipid syndrome
    • Win K, Rodgers GM. New oral anticoagulants may not be effective to prevent venous thromboembolism in patients with antiphospholipid syndrome. Am J Hematol 2014;89:1017.
    • (2014) Am J Hematol , vol.89 , pp. 1017
    • Win, K.1    Rodgers, G.M.2
  • 19
    • 85027933204 scopus 로고    scopus 로고
    • Rivaroxaban as an effective treatment for recurrent superficial thrombophlebitis related to primary antiphospholipid syndrome
    • Bachmeyer C, Elalamy I. Rivaroxaban as an effective treatment for recurrent superficial thrombophlebitis related to primary antiphospholipid syndrome. Clin Exp Dermatol 2014;39:840-1.
    • (2014) Clin Exp Dermatol , vol.39 , pp. 840-841
    • Bachmeyer, C.1    Elalamy, I.2
  • 20
    • 84938750673 scopus 로고    scopus 로고
    • Antiphospholipid syndrome of late onset: a difficult diagnosis of a recurrent embolic stroke
    • Delgado MG, Rodríguez S, García R et al. Antiphospholipid syndrome of late onset: a difficult diagnosis of a recurrent embolic stroke. J Stroke Cerebrovasc Dis 2015;24:e209-11.
    • (2015) J Stroke Cerebrovasc Dis , vol.24 , pp. e209-e211
    • Delgado, M.G.1    Rodríguez, S.2    García, R.3
  • 21
    • 84908252466 scopus 로고    scopus 로고
    • Seronegative antiphospholipid syndrome, catastrophic syndrome, new anticoagulants: learning from a difficult case report
    • Joalland F, de Boysson H, Darnige L et al. [Seronegative antiphospholipid syndrome, catastrophic syndrome, new anticoagulants: learning from a difficult case report]. Rev Med Interne 2014;35:752-6.
    • (2014) Rev Med Interne , vol.35 , pp. 752-756
    • Joalland, F.1    de Boysson, H.2    Darnige, L.3
  • 22
    • 84928625226 scopus 로고    scopus 로고
    • The use of rivaroxaban in patients with antiphospholipid syndrome: a series of 12 cases
    • Son M, Wypasek E, Celinska-Lowenhoff M, Undas A. The use of rivaroxaban in patients with antiphospholipid syndrome: a series of 12 cases. Thromb Res 2015;135:1035-6.
    • (2015) Thromb Res , vol.135 , pp. 1035-1036
    • Son, M.1    Wypasek, E.2    Celinska-Lowenhoff, M.3    Undas, A.4
  • 23
    • 84930759043 scopus 로고    scopus 로고
    • Safety and efficacy of oral direct inhibitors of thrombin and factor Xa in antiphospholipid syndrome
    • Noel N, Dutasta F, Costedoat-Chalumeau N et al. Safety and efficacy of oral direct inhibitors of thrombin and factor Xa in antiphospholipid syndrome. Autoimmun Rev 2015;14:680-5.
    • (2015) Autoimmun Rev , vol.14 , pp. 680-685
    • Noel, N.1    Dutasta, F.2    Costedoat-Chalumeau, N.3
  • 24
    • 84908550562 scopus 로고    scopus 로고
    • Failure of dabigatran and rivaroxaban to prevent thromboembolism in antiphospholipid syndrome: a case series of three patients
    • Schaefer JK, McBane RD, Black DF et al. Failure of dabigatran and rivaroxaban to prevent thromboembolism in antiphospholipid syndrome: a case series of three patients. Thromb Haemost 2014;112:947-50.
    • (2014) Thromb Haemost , vol.112 , pp. 947-950
    • Schaefer, J.K.1    McBane, R.D.2    Black, D.F.3
  • 26
    • 84938784417 scopus 로고    scopus 로고
    • Rivaroxaban in antiphospholipid syndrome (RAPS) protocol: a prospective, randomized controlled phase II/III clinical trial of rivaroxaban versus warfarin in patients with thrombotic antiphospholipid syndrome, with or without SLE
    • Cohen H, DoréCJ, Clawson S et al. Rivaroxaban in antiphospholipid syndrome (RAPS) protocol: a prospective, randomized controlled phase II/III clinical trial of rivaroxaban versus warfarin in patients with thrombotic antiphospholipid syndrome, with or without SLE. Lupus 2015;24:1087-94.
    • (2015) Lupus , vol.24 , pp. 1087-1094
    • Cohen, H.1    Doré, C.J.2    Clawson, S.3
  • 27
    • 84955739198 scopus 로고    scopus 로고
    • Laboratory monitoring-a turning point in the use of new oral anticoagulants
    • Advance Access published 3 September 2015
    • Scridon A, Constantin Serban R. Laboratory monitoring-a turning point in the use of new oral anticoagulants. Ther Drug Monit 2015; Advance Access published 3 September 2015, doi: 10.1097/FTD.0000000000000247.
    • (2015) Ther Drug Monit
    • Scridon, A.1    Constantin Serban, R.2
  • 28
    • 84868210856 scopus 로고    scopus 로고
    • Effects on routine coagulation screens and assessment of anticoagulant intensity in patients taking oral dabigatran or rivaroxaban: guidance from the British Committee for Standards in Haematology
    • Baglin T, Keeling D, Kitchen S. Effects on routine coagulation screens and assessment of anticoagulant intensity in patients taking oral dabigatran or rivaroxaban: guidance from the British Committee for Standards in Haematology. Br J Haematol 2012;159:427-9.
    • (2012) Br J Haematol , vol.159 , pp. 427-429
    • Baglin, T.1    Keeling, D.2    Kitchen, S.3
  • 29
    • 84867758291 scopus 로고    scopus 로고
    • Interference of the new oral anticoagulant dabigatran with frequently used coagulation tests
    • Halbmayer W-M, Weigel G, Quehenberger P et al. Interference of the new oral anticoagulant dabigatran with frequently used coagulation tests. Clin Chem Lab Med 2012;50:1601-5.
    • (2012) Clin Chem Lab Med , vol.50 , pp. 1601-1605
    • Halbmayer, W.-M.1    Weigel, G.2    Quehenberger, P.3
  • 30
    • 84867255276 scopus 로고    scopus 로고
    • The new oral anticoagulants and the future of haemostasis laboratory testing
    • Favaloro EJ, Lippi G. The new oral anticoagulants and the future of haemostasis laboratory testing. Biochem medica 2012;22:329-41.
    • (2012) Biochem medica , vol.22 , pp. 329-341
    • Favaloro, E.J.1    Lippi, G.2
  • 31
    • 77953168824 scopus 로고    scopus 로고
    • Dabigatran etexilate-a novel, reversible, oral direct thrombin inhibitor: Interpretation of coagulation assays and reversal of anticoagulant activity
    • van Ryn J, Stangier J, Haertter S et al. Dabigatran etexilate-a novel, reversible, oral direct thrombin inhibitor: Interpretation of coagulation assays and reversal of anticoagulant activity. Thromb Haemost 2010;103:1116-27.
    • (2010) Thromb Haemost , vol.103 , pp. 1116-1127
    • van Ryn, J.1    Stangier, J.2    Haertter, S.3
  • 32
    • 79851482951 scopus 로고    scopus 로고
    • Effects of the oral, direct thrombin inhibitor dabigatran on five common coagulation assays
    • Lindahl TL, Baghaei F, Blixter IF et al. Effects of the oral, direct thrombin inhibitor dabigatran on five common coagulation assays. Thromb Haemost 2011;105:371-8.
    • (2011) Thromb Haemost , vol.105 , pp. 371-378
    • Lindahl, T.L.1    Baghaei, F.2    Blixter, I.F.3
  • 33
    • 79954534386 scopus 로고    scopus 로고
    • Laboratory assessment of new anticoagulants
    • Samama MM, Guinet C. Laboratory assessment of new anticoagulants. Clin Chem Lab Med 2011;49:761-72.
    • (2011) Clin Chem Lab Med , vol.49 , pp. 761-772
    • Samama, M.M.1    Guinet, C.2
  • 34
    • 77952044405 scopus 로고    scopus 로고
    • Assessment of laboratory assays to measure rivaroxaban-an oral, direct factor Xa inhibitor
    • Samama MM, Martinoli J-L, LeFlem L et al. Assessment of laboratory assays to measure rivaroxaban-an oral, direct factor Xa inhibitor. Thromb Haemost 2010;103:815-25.
    • (2010) Thromb Haemost , vol.103 , pp. 815-825
    • Samama, M.M.1    Martinoli, J.-L.2    LeFlem, L.3
  • 35
    • 77249146517 scopus 로고    scopus 로고
    • Laboratory monitoring of new anticoagulants
    • Castellone DD, Van Cott EM. Laboratory monitoring of new anticoagulants. Am J Hematol 2010;85:185-7.
    • (2010) Am J Hematol , vol.85 , pp. 185-187
    • Castellone, D.D.1    Van Cott, E.M.2
  • 36
    • 84873544394 scopus 로고    scopus 로고
    • Laboratory assessment of the anticoagulant effects of the next generation of oral anticoagulants
    • Garcia D, Barrett YC, Ramacciotti E, Weitz JI. Laboratory assessment of the anticoagulant effects of the next generation of oral anticoagulants. J Thromb Haemost 2013;11:245-52.
    • (2013) J Thromb Haemost , vol.11 , pp. 245-252
    • Garcia, D.1    Barrett, Y.C.2    Ramacciotti, E.3    Weitz, J.I.4
  • 37
    • 70350004861 scopus 로고    scopus 로고
    • Update of the guidelines for lupus anticoagulant detection
    • Pengo V, Tripodi A, Reber G et al. Update of the guidelines for lupus anticoagulant detection. J Thromb Haemost 2009;7:1737-40.
    • (2009) J Thromb Haemost , vol.7 , pp. 1737-1740
    • Pengo, V.1    Tripodi, A.2    Reber, G.3
  • 38
    • 79960261824 scopus 로고    scopus 로고
    • Guidelines on oral anticoagulation with warfarin-fourth edition
    • Keeling D, Baglin T, Tait C et al. Guidelines on oral anticoagulation with warfarin-fourth edition. Br J Haematol 2011;154:311-24.
    • (2011) Br J Haematol , vol.154 , pp. 311-324
    • Keeling, D.1    Baglin, T.2    Tait, C.3
  • 39
    • 79851471020 scopus 로고    scopus 로고
    • Rivaroxaban and false positive lupus anticoagulant testing
    • Merriman E, Kaplan Z, Butler J et al. Rivaroxaban and false positive lupus anticoagulant testing. Thromb Haemost 2011;105:385-6.
    • (2011) Thromb Haemost , vol.105 , pp. 385-386
    • Merriman, E.1    Kaplan, Z.2    Butler, J.3
  • 41
    • 84896116136 scopus 로고    scopus 로고
    • Frequent false-positive results of lupus anticoagulant tests in plasmas of patients receiving the new oral anticoagulants and enoxaparin
    • Martinuzzo ME, Barrera LH, D'adamo MA et al. Frequent false-positive results of lupus anticoagulant tests in plasmas of patients receiving the new oral anticoagulants and enoxaparin. Int J Lab Hematol 2014;36:144-50.
    • (2014) Int J Lab Hematol , vol.36 , pp. 144-150
    • Martinuzzo, M.E.1    Barrera, L.H.2    D'adamo, M.A.3
  • 42
    • 84935693839 scopus 로고    scopus 로고
    • Interactions between rivaroxaban and antiphospholipid antibodies in thrombotic antiphospholipid syndrome
    • Arachchillage DRJ, Mackie IJ, Efthymiou M et al. Interactions between rivaroxaban and antiphospholipid antibodies in thrombotic antiphospholipid syndrome. J Thromb Haemost 2015;13:1264-73.
    • (2015) J Thromb Haemost , vol.13 , pp. 1264-1273
    • Arachchillage, D.R.J.1    Mackie, I.J.2    Efthymiou, M.3
  • 44
    • 37149005153 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of the direct oral thrombin inhibitor dabigatran in healthy elderly subjects
    • Stangier J, Stähle H, Rathgen K, Fuhr R. Pharmacokinetics and pharmacodynamics of the direct oral thrombin inhibitor dabigatran in healthy elderly subjects. Clin Pharmacokinet 2008;47:47-59.
    • (2008) Clin Pharmacokinet , vol.47 , pp. 47-59
    • Stangier, J.1    Stähle, H.2    Rathgen, K.3    Fuhr, R.4
  • 45
    • 79957715797 scopus 로고    scopus 로고
    • Anticoagulant options-why the FDA approved a higher but not a lower dose of dabigatran
    • Beasley BN, Unger EF, Temple R. Anticoagulant options-why the FDA approved a higher but not a lower dose of dabigatran. N Engl J Med 2011;364:1788-90.
    • (2011) N Engl J Med , vol.364 , pp. 1788-1790
    • Beasley, B.N.1    Unger, E.F.2    Temple, R.3
  • 46
    • 84964258745 scopus 로고    scopus 로고
    • Effect of renal impairment on the pharmacokinetics, pharmacodynamics, and safety of apixaban
    • Advance Access published 11 September 2015
    • Chang M, Yu Z, Shenker A et al. Effect of renal impairment on the pharmacokinetics, pharmacodynamics, and safety of apixaban. J Clin Pharmacol 2015; Advance Access published 11 September 2015, doi: 10.1002/jcph.633.
    • (2015) J Clin Pharmacol
    • Chang, M.1    Yu, Z.2    Shenker, A.3
  • 47
    • 4644224760 scopus 로고    scopus 로고
    • (1 September 2015, date last accessed).
    • Eliquis 2.5mg film-coated tablets film-coated tablets. Summary of Product Characteristics (SPC). 2012. www.emc. medicines.org.uk (1 September 2015, date last accessed).
    • (2012) Summary of Product Characteristics (SPC)
  • 48
    • 84877069414 scopus 로고    scopus 로고
    • Anticoagulant therapy with the oral direct factor Xa inhibitors rivaroxaban, apixaban and edoxaban and the thrombin inhibitor dabigatran etexilate in patients with hepatic impairment
    • Graff J, Harder S. Anticoagulant therapy with the oral direct factor Xa inhibitors rivaroxaban, apixaban and edoxaban and the thrombin inhibitor dabigatran etexilate in patients with hepatic impairment. Clin Pharmacokinet 2013;52:243-54.
    • (2013) Clin Pharmacokinet , vol.52 , pp. 243-254
    • Graff, J.1    Harder, S.2
  • 49
    • 84891701713 scopus 로고    scopus 로고
    • Use of new oral anticoagulants in antiphospholipid syndrome
    • Arachchillage DJ, Cohen H. Use of new oral anticoagulants in antiphospholipid syndrome. Curr Rheumatol Rep 2013;15:331.
    • (2013) Curr Rheumatol Rep , vol.15 , pp. 331
    • Arachchillage, D.J.1    Cohen, H.2
  • 50
    • 77952118055 scopus 로고    scopus 로고
    • (1 September 2015, date last accessed).
    • European Medicines Agency. Xarelto. Summary of Product Characteristics (SPC). 2013. http://www.ema. europa.eu/docs/en_GB/document_library/EPAR_-_ Product_Information/human/000944/WC500057108.pdf (1 September 2015, date last accessed).
    • (2013) Summary of Product Characteristics (SPC)
  • 51
    • 84963991419 scopus 로고    scopus 로고
    • (1 September 2015, date last accessed).
    • European Medicines Agency. Pradaxa. Summary of Product Characteristics (SPC). 2015. http://www.ema. europa.eu/docs/en_GB/document_library/EPAR_-_ Product_Information/human/000829/WC500041059.pdf (1 September 2015, date last accessed).
    • (2015) Summary of Product Characteristics (SPC)
  • 53
    • 84866866045 scopus 로고    scopus 로고
    • Phase III studies on novel oral anticoagulants for stroke prevention in atrial fibrillation: a look beyond the excellent results
    • Pengo V, Crippa L, Falanga A et al. Phase III studies on novel oral anticoagulants for stroke prevention in atrial fibrillation: a look beyond the excellent results. J Thromb Haemost 2012;10:1979-87.
    • (2012) J Thromb Haemost , vol.10 , pp. 1979-1987
    • Pengo, V.1    Crippa, L.2    Falanga, A.3
  • 54
    • 84946569791 scopus 로고    scopus 로고
    • Risk of fatal bleeding in episodes of major bleeding with new oral anticoagulants and vitamin k antagonists: a systematic review and meta-analysis
    • Skaistis J, Tagami T. Risk of fatal bleeding in episodes of major bleeding with new oral anticoagulants and vitamin k antagonists: a systematic review and meta-analysis. PLoS One 2015;10:e0137444.
    • (2015) PLoS One , vol.10
    • Skaistis, J.1    Tagami, T.2
  • 55
    • 70349306707 scopus 로고    scopus 로고
    • Dabigatran versus warfarin in patients with atrial fibrillation
    • Connolly SJ, Ezekowitz MD, Yusuf S et al. Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med 2009;361:1139-51.
    • (2009) N Engl J Med , vol.361 , pp. 1139-1151
    • Connolly, S.J.1    Ezekowitz, M.D.2    Yusuf, S.3
  • 56
    • 79961199378 scopus 로고    scopus 로고
    • Oral rivaroxaban after symptomatic venous thromboembolism: the continued treatment study (EINSTEIN-extension study)
    • Romualdi E, Donadini MP, Ageno W. Oral rivaroxaban after symptomatic venous thromboembolism: the continued treatment study (EINSTEIN-extension study). Expert Rev Cardiovasc Ther 2011;9:841-4.
    • (2011) Expert Rev Cardiovasc Ther , vol.9 , pp. 841-844
    • Romualdi, E.1    Donadini, M.P.2    Ageno, W.3
  • 57
    • 84957111517 scopus 로고    scopus 로고
    • Bleeding events with dabigatran or warfarin in patients with venous thromboembolism
    • Advance Access published 24 September 2015
    • Majeed A, Goldhaber SZ, Kakkar A et al. Bleeding events with dabigatran or warfarin in patients with venous thromboembolism. Thromb Haemost 2015;115; Advance Access published 24 September 2015, doi: 10.1160/TH15-04-0319.
    • (2015) Thromb Haemost , vol.115
    • Majeed, A.1    Goldhaber, S.Z.2    Kakkar, A.3
  • 58
    • 84943601987 scopus 로고    scopus 로고
    • Management of bleeding associated with new oral anticoagulants
    • Franchini M, Bonfanti C, Mannucci PM. Management of bleeding associated with new oral anticoagulants. Semin Thromb Hemost 2015;41:788-801.
    • (2015) Semin Thromb Hemost , vol.41 , pp. 788-801
    • Franchini, M.1    Bonfanti, C.2    Mannucci, P.M.3
  • 59
    • 80054891473 scopus 로고    scopus 로고
    • The new oral anticoagulants
    • Breen K, Hunt B. The new oral anticoagulants. Clin Med 2011;11:467-9.
    • (2011) Clin Med , vol.11 , pp. 467-469
    • Breen, K.1    Hunt, B.2
  • 60
    • 84908347488 scopus 로고    scopus 로고
    • New oral anticoagulants in the management of venous thromboembolism: a major advance?
    • Sciascia S, Hunt BJ. New oral anticoagulants in the management of venous thromboembolism: a major advance? Eur J Vasc Endovasc Surg 2014;48:487-8.
    • (2014) Eur J Vasc Endovasc Surg , vol.48 , pp. 487-488
    • Sciascia, S.1    Hunt, B.J.2
  • 61
    • 84908502375 scopus 로고    scopus 로고
    • Comparison of threefactor and four-factor prothrombin complex concentrates regarding reversal of the anticoagulant effects of rivaroxaban in healthy volunteers
    • Levi M, Moore KT, Castillejos CF et al. Comparison of threefactor and four-factor prothrombin complex concentrates regarding reversal of the anticoagulant effects of rivaroxaban in healthy volunteers. J Thromb Haemost 2014;12:1428-36.
    • (2014) J Thromb Haemost , vol.12 , pp. 1428-1436
    • Levi, M.1    Moore, K.T.2    Castillejos, C.F.3
  • 62
    • 84942906025 scopus 로고    scopus 로고
    • In vivo increase in thrombin generation by four-factor prothrombin complex concentrate in apixaban-treated healthy volunteers
    • Cheung YW, Barco S, Hutten BA et al. In vivo increase in thrombin generation by four-factor prothrombin complex concentrate in apixaban-treated healthy volunteers. J Thromb Haemost 2015;13:1799-805.
    • (2015) J Thromb Haemost , vol.13 , pp. 1799-1805
    • Cheung, Y.W.1    Barco, S.2    Hutten, B.A.3
  • 63
    • 84896106773 scopus 로고    scopus 로고
    • Reversal of rivaroxaban-induced anticoagulation with prothrombin complex concentrate, activated prothrombin complex concentrate and recombinant activated factor VII in vitro
    • Perzborn E, Heitmeier S, Laux V, Buchmüller A. Reversal of rivaroxaban-induced anticoagulation with prothrombin complex concentrate, activated prothrombin complex concentrate and recombinant activated factor VII in vitro. Thromb Res 2014;133:671-81.
    • (2014) Thromb Res , vol.133 , pp. 671-681
    • Perzborn, E.1    Heitmeier, S.2    Laux, V.3    Buchmüller, A.4
  • 64
    • 84892921288 scopus 로고    scopus 로고
    • Reversal of apixaban induced alterations in hemostasis by different coagulation factor concentrates: significance of studies in vitro with circulating human blood
    • Escolar G, Fernandez-Gallego V, Arellano-Rodrigo E et al. Reversal of apixaban induced alterations in hemostasis by different coagulation factor concentrates: significance of studies in vitro with circulating human blood. PLoS One 2013;8:e78696.
    • (2013) PLoS One , vol.8
    • Escolar, G.1    Fernandez-Gallego, V.2    Arellano-Rodrigo, E.3
  • 65
    • 84928254284 scopus 로고    scopus 로고
    • Reversal of rivaroxaban-induced alterations on hemostasis by different coagulation factor concentrates-in vitro studies with steady and circulating human blood
    • Escolar G, Arellano-Rodrigo E, Lopez-Vilchez I et al. Reversal of rivaroxaban-induced alterations on hemostasis by different coagulation factor concentrates-in vitro studies with steady and circulating human blood. Circ J 2015;79:331-8.
    • (2015) Circ J , vol.79 , pp. 331-338
    • Escolar, G.1    Arellano-Rodrigo, E.2    Lopez-Vilchez, I.3
  • 66
    • 80053571188 scopus 로고    scopus 로고
    • Reversal of rivaroxaban and dabigatran by prothrombin complex concentrate: a randomized, placebo-controlled, crossover study in healthy subjects
    • Eerenberg ES, Kamphuisen PW, Sijpkens MK et al. Reversal of rivaroxaban and dabigatran by prothrombin complex concentrate: a randomized, placebo-controlled, crossover study in healthy subjects. Circulation 2011;124:1573-9.
    • (2011) Circulation , vol.124 , pp. 1573-1579
    • Eerenberg, E.S.1    Kamphuisen, P.W.2    Sijpkens, M.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.