Matrix metalloproteinase 12 is an indicator of intervertebral disc degeneration co-expressed with fibrotic markers

Osteoarthritis and Cartilage

Volumn 24, Issue 10, 2016, Pages 1826-1836

  Lv, F J ^a,b,c   Peng, Y ^a   Lim, F L ^a   Sun, Y ^a,c   Lv, M ^d   Zhou, L ^a   Wang, H ^e   Zheng, Z ^e   Cheung, K M C ^a,c   Leung, V Y L ^a,b,c  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF HONG KONG   (China)

^c UNIVERSITY OF HONG KONG   (Hong Kong)

^d Advanced Technology Research Institution of China Science Institution   (China)

^e SUN YAT SEN UNIVERSITY   (China)

Author keywords

Degeneration; Intervertebral disc; Matrix metalloproteinase; MMP12; Myofibroblast; Nucleus pulposus

Indexed keywords

AGGRECAN; ALPHA SMOOTH MUSCLE ACTIN; BIOLOGICAL MARKER; CADHERIN 2; CALVASCULIN; CARTILAGE OLIGOMERIC MATRIX PROTEIN; COLLAGEN TYPE 1; COLLAGEN TYPE 3; CYTOKERATIN 18; CYTOKERATIN 19; FIBROBLAST ACTIVATED PROTEIN; FIBRONECTIN; FIBULIN 1; FLUORESCENT DYE; HEAT SHOCK PROTEIN 47; MACROPHAGE ELASTASE; MATRIX GLA PROTEIN; PICROSIRIUS RED; TRANSCRIPTION FACTOR SOX9; UNCLASSIFIED DRUG;

ACAN GENE; ADOLESCENT; ADULT; AGING; ANIMAL CELL; ANIMAL TISSUE; ANNULUS FIBROSUS; ARTICLE; CARTILAGE CELL; CDH2 GENE; CLINICAL ARTICLE; COL1A1 GENE; COL3A1 GENE; COMP GENE; CONTROLLED STUDY; DISEASE MARKER; DISEASE SEVERITY; FBLN1 GENE; FEMALE; FIBROSIS; FN1 GENE; GENE; GENE EXPRESSION; GENETIC TRANSCRIPTION; HISTOPATHOLOGY; HSP47 GENE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTERVERTEBRAL DISK DEGENERATION; KRT18 GENE; KRT19 GENE; MALE; MGP GENE; MIDDLE AGED; MMP12 GENE; MOUSE; MYOFIBROBLAST; NONHUMAN; NUCLEUS PULPOSUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PUNCTURE; RASAL1 GENE; RAT; SOX9 GENE; ANIMAL; INTERVERTEBRAL DISK;

ANIMALS; BIOMARKERS; FIBROSIS; HUMANS; INTERVERTEBRAL DISC; INTERVERTEBRAL DISC DEGENERATION; MATRIX METALLOPROTEINASE 12; MICE; NUCLEUS PULPOSUS; RATS;

EID: 84990889348     PISSN: 10634584     EISSN: 15229653     Source Type: Journal    
DOI: 10.1016/j.joca.2016.05.012     Document Type: Article

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