Effects of a metalloproteinase inhibitor on osteochondral angiogenesis, chondropathy and pain behavior in a rat model of osteoarthritis

Osteoarthritis and Cartilage

Volumn 18, Issue 4, 2010, Pages 593-600

  Mapp, P I ^a   Walsh, D A ^a   Bowyer, J ^b   Maciewicz, R A ^b  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

Author keywords

Chondropathy; Osteoarthritis; Osteochondral angiogenesis; Pain behavior; Rat model

Indexed keywords

COLLAGENASE 3; GELATINASE A; GELATINASE B; M 503902; MACROPHAGE ELASTASE; METALLOPROTEINASE INHIBITOR; NEUTROPHIL COLLAGENASE; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHONDROPATHY; CONTROLLED STUDY; DRUG EFFECT; HISTOLOGY; KNEE LIGAMENT; KNEE MENISCUS; KNEE OSTEOARTHRITIS; KNEE PAIN; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SYMPTOM; VASCULARIZATION; WEIGHT BEARING;

ANIMALS; BEHAVIOR, ANIMAL; CARTILAGE, ARTICULAR; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; KNEE JOINT; MALE; MATRIX METALLOPROTEINASES; MENISCI, TIBIAL; NEOVASCULARIZATION, PATHOLOGIC; OSTEOARTHRITIS; PAIN; RATS; RATS, INBRED LEW; WEIGHT-BEARING;

EID: 77950022355     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joca.2009.12.006     Document Type: Article

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