ERK activation in endothelial cells is a novel marker during neovasculogenesis

Genes to Cells

Volumn 21, Issue 11, 2016, Pages 1164-1175

  Nagasawa Masuda, Ayumi ^a   Terai, Kenta ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; ZEBRAFISH PROTEIN;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL STRUCTURES; ARTICLE; CELLULAR PARAMETERS; CONTROLLED STUDY; DORSAL AORTA; EMBRYO; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME REGULATION; INTERSEGMENTAL VESSEL; LYMPHANGIOGENESIS; NONHUMAN; PARACHORDAL VESSEL; PRIORITY JOURNAL; STALK CELL; TAIL VEIN; TIP CELL; ZEBRA FISH; ANIMAL; AORTA; CYTOLOGY; EMBRYOLOGY; ENZYMOLOGY; METABOLISM; VEIN;

ANIMALS; AORTA; ENDOTHELIAL CELLS; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; NEOVASCULARIZATION, PHYSIOLOGIC; VEINS; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 84990228909     PISSN: 13569597     EISSN: 13652443     Source Type: Journal    
DOI: 10.1111/gtc.12438     Document Type: Article

References (42)

1. Abdus-Saboor, I., Mancuso, V.P., Murray, J.I., Palozola, K., Norris, C., Hall, D.H., Howell, K., Huang, K. & Sundaram, M.V. (2011) Notch and Ras promote sequential steps of excretory tube development in C. elegans. Development 138, 3545–3555.
2. Alitalo, K. (2011) The lymphatic vasculature in disease. Nat. Med. 17, 1371–1380.
3. Carmeliet, P. & Jain, R.K. (2011) Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases. Nat. Rev. Drug Discov. 10, 417–427.
4. Carmeliet, P. & Tessier-Lavigne, M. (2005) Common mechanisms of nerve and blood vessel wiring. Nature 436, 193–200.
5. Cha, Y.R., Fujita, M., Butler, M., Isogai, S., Kochhan, E., Siekmann, A.F. & Weinstein, B.M. (2012) Chemokine signaling directs trunk lymphatic network formation along the preexisting blood vasculature. Dev. Cell 22, 824–836.
6. Flores, M.V., Hall, C.J., Crosier, K.E. & Crosier, P.S. (2010) Visualization of embryonic lymphangiogenesis advances the use of the zebrafish model for research in cancer and lymphatic pathologies. Dev. Dyn. 239, 2128–2135.
7. Gale, N.W., Prevo, R., Espinosa, J., Ferguson, D.J., Dominguez, M.G., Yancopoulos, G.D., Thurston, G. & Jackson, D.G. (2007) Normal lymphatic development and function in mice deficient for the lymphatic hyaluronan receptor LYVE-1. Mol. Cell. Biol. 27, 595–604.
8. Hellstrom, M., Phng, L.K., Hofmann, J.J. et al. (2007) Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis. Nature 445, 776–780.
9. Herbert, S.P., Cheung, J.Y. & Stainier, D.Y. (2012) Determination of endothelial stalk versus tip cell potential during angiogenesis by H2.0-like homeobox-1. Curr. Biol. 22, 1789–1794.
10. Herbert, S.P. & Stainier, D.Y. (2011) Molecular control of endothelial cell behaviour during blood vessel morphogenesis. Nat. Rev. Mol. Cell Biol. 12, 551–564.
11. Hogan, B.M., Bos, F.L., Bussmann, J., Witte, M., Chi, N.C., Duckers, H.J. & Schulte-Merker, S. (2009a) Ccbe1 is required for embryonic lymphangiogenesis and venous sprouting. Nat. Genet. 41, 396–398.
12. Hogan, B.M., Herpers, R., Witte, M., Helotera, H., Alitalo, K., Duckers, H.J. & Schulte-Merker, S. (2009b) Vegfc/Flt4 signalling is suppressed by Dll4 in developing zebrafish intersegmental arteries. Development 136, 4001–4009.
13. van Impel, A., Zhao, Z., Hermkens, D.M., Roukens, M.G., Fischer, J.C., Peterson-Maduro, J., Duckers, H., Ober, E.A., Ingham, P.W. & Schulte-Merker, S. (2014) Divergence of zebrafish and mouse lymphatic cell fate specification pathways. Development 141, 1228–1238.
14. Isogai, S., Horiguchi, M. & Weinstein, B.M. (2001) The vascular anatomy of the developing zebrafish: an atlas of embryonic and early larval development. Dev. Biol. 230, 278–301.
15. Karkkainen, M.J., Haiko, P., Sainio, K., Partanen, J., Taipale, J., Petrova, T.V., Jeltsch, M., Jackson, D.G., Talikka, M., Rauvala, H., Betsholtz, C. & Alitalo, K. (2004) Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins. Nat. Immunol. 5, 74–80.
16. Kashiwada, T., Fukuhara, S., Terai, K., Tanaka, T., Wakayama, Y., Ando, K., Nakajima, H., Fukui, H., Yuge, S., Saito, Y., Gemma, A. & Mochizuki, N. (2015) beta-Catenin-dependent transcription is central to Bmp-mediated formation of venous vessels. Development 142, 497–509.
17. Kawakami, K., Takeda, H., Kawakami, N., Kobayashi, M., Matsuda, N. & Mishina, M. (2004) A transposon-mediated gene trap approach identifies developmentally regulated genes in zebrafish. Dev. Cell 7, 133–144.
18. Keunen, O., Johansson, M., Oudin, A. et al. (2011) Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma. Proc. Natl Acad. Sci. USA 108, 3749–3754.
19. Kim, Y.S., Jung, S.H., Jung, D.H., Choi, S.J., Lee, Y.R. & Kim, J.S. (2014) Gas6 stimulates angiogenesis of human retinal endothelial cells and of zebrafish embryos via ERK1/2 signaling. PLoS One 9, e83901.
20. Kimmel, C.B., Ballard, W.W., Kimmel, S.R., Ullmann, B. & Schilling, T.F. (1995) Stages of embryonic development of the zebrafish. Dev. Dyn. 203, 253–310.
21. Koenig, A.L., Baltrunaite, K., Bower, N.I., Rossi, A., Stainier, D.Y.R., Hogan, B.M. & Sumanas, S. (2016) Vegfa signaling promotes zebrafish intestinal vasculature development through endothelial cell migration from the posterior cardinal vein. Dev. Biol. 411, 115–127.
22. Leslie, J.D., Ariza-McNaughton, L., Bermange, A.L., McAdow, R., Johnson, S.L. & Lewis, J. (2007) Endothelial signalling by the Notch ligand Delta-like 4 restricts angiogenesis. Development 134, 839–844.
23. Lobov, I.B., Renard, R.A., Papadopoulos, N., Gale, N.W., Thurston, G., Yancopoulos, G.D. & Wiegand, S.J. (2007) Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting. Proc. Natl Acad. Sci. USA 104, 3219–3224.
24. Milanini, J., Vinals, F., Pouyssegur, J. & Pages, G. (1998) p42/p44 MAP kinase module plays a key role in the transcriptional regulation of the vascular endothelial growth factor gene in fibroblasts. J. Biol. Chem. 273, 18165–18172.
25. Nakao, S., Zandi, S., Lara-Castillo, N., Taher, M., Ishibashi, T. & Hafezi-Moghadam, A. (2012) Larger therapeutic window for steroid versus VEGF-A inhibitor in inflammatory angiogenesis: surprisingly similar impact on leukocyte infiltration. Invest. Ophthalmol. Vis. Sci. 53, 3296–3302.
26. Nicenboim, J., Malkinson, G., Lupo, T. et al. (2015) Lymphatic vessels arise from specialized angioblasts within a venous niche. Nature 522, 56–61.
27. Okajima, E. & Thorgeirsson, U.P. (2000) Different regulation of vascular endothelial growth factor expression by the ERK and p38 kinase pathways in v-ras, v-raf, and v-myc transformed cells. Biochem. Biophys. Res. Commun. 270, 108–111.
28. Okuda, K.S., Astin, J.W., Misa, J.P., Flores, M.V., Crosier, K.E. & Crosier, P.S. (2012) lyve1 expression reveals novel lymphatic vessels and new mechanisms for lymphatic vessel development in zebrafish. Development 139, 2381–2391.
29. Rao, N., Lee, Y.F. & Ge, R. (2015) Novel endogenous angiogenesis inhibitors and their therapeutic potential. Acta Pharmacol. Sin. 36, 1177–1190.
30. Scott, E.K., Mason, L., Arrenberg, A.B., Ziv, L., Gosse, N.J., Xiao, T., Chi, N.C., Asakawa, K., Kawakami, K. & Baier, H. (2007) Targeting neural circuitry in zebrafish using GAL4 enhancer trapping. Nat. Methods 4, 323–326.
31. Seger, R. & Krebs, E.G. (1995) The MAPK signaling cascade. FASEB J. 9, 726–735.
32. Sharrocks, A.D. (2001) The ETS-domain transcription factor family. Nat. Rev. Mol. Cell Biol. 2, 827–837.
33. Siekmann, A.F. & Lawson, N.D. (2007) Notch signalling limits angiogenic cell behaviour in developing zebrafish arteries. Nature 445, 781–784.
34. Suchting, S., Freitas, C., le Noble, F., Benedito, R., Breant, C., Duarte, A. & Eichmann, A. (2007) The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching. Proc. Natl Acad. Sci. USA 104, 3225–3230.
35. Takeuchi, M., Matsuda, K., Yamaguchi, S., Asakawa, K., Miyasaka, N., Lal, P., Yoshihara, Y., Koga, A., Kawakami, K., Shimizu, T. & Hibi, M. (2015) Establishment of Gal4 transgenic zebrafish lines for analysis of development of cerebellar neural circuitry. Dev. Biol. 397, 1–17.
36. Tammela, T. & Alitalo, K. (2010) Lymphangiogenesis: molecular mechanisms and future promise. Cell 140, 460–476.
37. Tammela, T., Zarkada, G., Wallgard, E. et al. (2008) Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation. Nature 454, 656–660.
38. Thisse, C. & Thisse, B. (2008) High-resolution in situ hybridization to whole-mount zebrafish embryos. Nat Protoc 3, 59–69.
39. Villefranc, J.A., Nicoli, S., Bentley, K., Jeltsch, M., Zarkada, G., Moore, J.C., Gerhardt, H., Alitalo, K. & Lawson, N.D. (2013) A truncation allele in vascular endothelial growth factor c reveals distinct modes of signaling during lymphatic and vascular development. Development 140, 1497–1506.
40. Wang, Y., Chang, J., Chen, K.D., Li, S., Li, J.Y., Wu, C. & Chien, S. (2007) Selective adapter recruitment and differential signaling networks by VEGF vs. shear stress. Proc. Natl Acad. Sci. USA 104, 8875–8879.
41. Wigle, J.T. & Oliver, G. (1999) Prox1 function is required for the development of the murine lymphatic system. Cell 98, 769–778.
42. Yaniv, K., Isogai, S., Castranova, D., Dye, L., Hitomi, J. & Weinstein, B.M. (2006) Live imaging of lymphatic development in the zebrafish. Nat. Med. 12, 711–716.