-
1
-
-
0030936323
-
PTEN, a putative protein tyrosine phosphatase gene mutatedin human brain, breast, and prostate cancer
-
Li J, Yen C, Liaw D et al (1997) PTEN, a putative protein tyrosine phosphatase gene mutatedin human brain, breast, and prostate cancer. Science 275(5308):1943-1947
-
(1997)
Science
, vol.275
, Issue.5308
, pp. 1943-1947
-
-
Li, J.1
Yen, C.2
Liaw, D.3
-
2
-
-
84885735554
-
Mutational landscape and significanceacross 12 major cancer types
-
Kandoth C, McLellan MD, Vandin F et al (2013) Mutational landscape and significanceacross 12 major cancer types. Nature 502(7471):333-339
-
(2013)
Nature
, vol.502
, Issue.7471
, pp. 333-339
-
-
Kandoth, C.1
McLellan, M.D.2
Vandin, F.3
-
3
-
-
84860217431
-
Thefunctions and regulation of the PTEN tumour suppressor
-
Song MS, Salmena L, PandolfiPP (2012) Thefunctions and regulation of the PTEN tumour suppressor. Nat Rev Mol Cell Biol 13(5):283-296
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, Issue.5
, pp. 283-296
-
-
Song, M.S.1
Salmena, L.2
Pandolfi, P.P.3
-
4
-
-
84880737776
-
A secreted PTEN phosphatase that enters cells to alter signaling and survival
-
Hopkins BD, Fine B, Steinbach N et al (2013) A secreted PTEN phosphatase that enters cells to alter signaling and survival. Science 341(6144):399-402
-
(2013)
Science
, vol.341
, Issue.6144
, pp. 399-402
-
-
Hopkins, B.D.1
Fine, B.2
Steinbach, N.3
-
5
-
-
84903768994
-
A unified nomenclature and amino acid numbering for human PTEN
-
Pulido R, Baker SJ, Barata JT et al (2014) A unified nomenclature and amino acid numbering for human PTEN. Sci Signal 7(332), e15
-
(2014)
Sci Signal
, vol.7
, Issue.332
, pp. 15
-
-
Pulido, R.1
Baker, S.J.2
Barata, J.T.3
-
6
-
-
84895823244
-
RapidCaP, a novel GEM model for metastatic prostate cancer analysis and therapy, reveals myc as a driver of Pten-mutant metastasis
-
Cho H, Herzka T, Zheng W et al (2014) RapidCaP, a novel GEM model for metastatic prostate cancer analysis and therapy, reveals myc as a driver of Pten-mutant metastasis. Cancer Discov 4(3):318-333
-
(2014)
Cancer Discov
, vol.4
, Issue.3
, pp. 318-333
-
-
Cho, H.1
Herzka, T.2
Zheng, W.3
-
7
-
-
34447123124
-
Improved prediction of prostate cancer recurrence through systems pathology
-
Cordon-Cardo C, Kotsianti A, Verbel DA et al (2007) Improved prediction of prostate cancer recurrence through systems pathology. J Clin Invest 117(7):1876-1883
-
(2007)
J Clin Invest
, vol.117
, Issue.7
, pp. 1876-1883
-
-
Cordon-Cardo, C.1
Kotsianti, A.2
Verbel, D.A.3
-
9
-
-
79951958340
-
A robust immunohistochemical assay for detecting PTEN expression in human tumors
-
Sangale Z, Prass C, Carlson A et al (2011) A robust immunohistochemical assay for detecting PTEN expression in human tumors. Appl Immunohistochem Mol Morphol 19(2):173-183
-
(2011)
Appl Immunohistochem Mol Morphol
, vol.19
, Issue.2
, pp. 173-183
-
-
Sangale, Z.1
Prass, C.2
Carlson, A.3
-
10
-
-
84862777505
-
Clinical assessment of PTEN loss in endometrial carcinoma: Immunohistochemistry outperforms gene sequencing
-
Djordjevic B, Hennessy BT, Li J et al (2012) Clinical assessment of PTEN loss in endometrial carcinoma: immunohistochemistry outperforms gene sequencing. Mod Pathol 25(5):699-708
-
(2012)
Mod Pathol
, vol.25
, Issue.5
, pp. 699-708
-
-
Djordjevic, B.1
Hennessy, B.T.2
Li, J.3
-
11
-
-
57549098807
-
The Catalogue of Somatic Mutations in Cancer (COSMIC)
-
Chapter 10:Unit 10 1
-
Forbes SA, Bhamra G, Bamford S et al (2008) The Catalogue of Somatic Mutations in Cancer (COSMIC). Curr Protoc Hum Genet Chapter 10:Unit 10 1
-
(2008)
Curr Protoc Hum Genet
-
-
Forbes, S.A.1
Bhamra, G.2
Bamford, S.3
-
12
-
-
79960732694
-
PIK3CA mutation, but not PTEN loss of function, determines the sensitivity of breast cancer cells to mTOR inhibitory drugs
-
Weigelt B, Warne PH, Downward J (2011) PIK3CA mutation, but not PTEN loss of function, determines the sensitivity of breast cancer cells to mTOR inhibitory drugs. Oncogene 30(29):3222-3233
-
(2011)
Oncogene
, vol.30
, Issue.29
, pp. 3222-3233
-
-
Weigelt, B.1
Warne, P.H.2
Downward, J.3
-
13
-
-
84904079079
-
Automated quantitative multiplex immunofluorescence in situ imaging identifies phospho-S6 and phospho-PRAS40 as predictive protein biomarkers for prostate cancer lethality
-
Shipitsin M, Small C, Giladi E et al (2014) Automated quantitative multiplex immunofluorescence in situ imaging identifies phospho-S6 and phospho-PRAS40 as predictive protein biomarkers for prostate cancer lethality. Proteome Sci 12:40
-
(2014)
Proteome Sci
, vol.12
, pp. 40
-
-
Shipitsin, M.1
Small, C.2
Giladi, E.3
-
14
-
-
37749010579
-
Imaging mass spectrometry of proteins and peptides 3D volume reconstruction
-
Andersson M, Groseclose MR, Deutch AY et al (2008) Imaging mass spectrometry of proteins and peptides: 3D volume reconstruction. Nat Methods 5(1):101-108
-
(2008)
Nat Methods
, vol.5
, Issue.1
, pp. 101-108
-
-
Andersson, M.1
Groseclose, M.R.2
Deutch, A.Y.3
-
15
-
-
84878044033
-
MALDI imaging mass spectrometry: Statistical data analysis and current computational challenges
-
Alexandrov T (2012) MALDI imaging mass spectrometry: statistical data analysis and current computational challenges. BMC Bioinformatics 13(Suppl 16):S11
-
(2012)
BMC Bioinformatics
, vol.13
, pp. 11
-
-
Alexandrov, T.1
-
16
-
-
84863879050
-
Quantitative comparison of immunohistochemical staining measured by digital image analysis versus pathologist visual scoring
-
Rizzardi AE, Johnson AT, Vogel RI et al (2012) Quantitative comparison of immunohistochemical staining measured by digital image analysis versus pathologist visual scoring. Diagn Pathol 7:42
-
(2012)
Diagn Pathol
, vol.7
, pp. 42
-
-
Rizzardi, A.E.1
Johnson, A.T.2
Vogel, R.I.3
-
17
-
-
33748269365
-
Quantification of immunohistochemistry--issues concerning methods, utility and semiquantitative assessment II
-
Taylor CR, Levenson RM (2006) Quantification of immunohistochemistry--issues concerning methods, utility and semiquantitative assessment II. Histopathology 49(4):411-424
-
(2006)
Histopathology
, vol.49
, Issue.4
, pp. 411-424
-
-
Taylor, C.R.1
Levenson, R.M.2
-
18
-
-
33748752115
-
Quantification of immunohistochemistry--issues concerning methods, utility and semiquantitative assessment I
-
Walker RA (2006) Quantification of immunohistochemistry--issues concerning methods, utility and semiquantitative assessment I. Histopathology 49(4):406-410
-
(2006)
Histopathology
, vol.49
, Issue.4
, pp. 406-410
-
-
Walker, R.A.1
-
19
-
-
84900328733
-
Cross-species regulatory network analysis identifies a synergistic interaction between FOXM1 and CENPF that drives prostate cancer malignancy
-
Aytes A, Mitrofanova A, Lefebvre C et al (2014) Cross-species regulatory network analysis identifies a synergistic interaction between FOXM1 and CENPF that drives prostate cancer malignancy. Cancer Cell 25(5):638-651
-
(2014)
Cancer Cell
, vol.25
, Issue.5
, pp. 638-651
-
-
Aytes, A.1
Mitrofanova, A.2
Lefebvre, C.3
-
20
-
-
84884684430
-
A molecular signature predictive of indolent prostate cancer
-
202ra122
-
Irshad S, Bansal M, Castillo-Martin M et al (2013) A molecular signature predictive of indolent prostate cancer. Sci Transl Med 5(202):202ra122
-
(2013)
Sci Transl Med
, vol.5
, Issue.202
-
-
Irshad, S.1
Bansal, M.2
Castillo-Martin, M.3
-
21
-
-
84961288400
-
Study of PTEN subcellular localization
-
Bononi A, Pinton P (2015) Study of PTEN subcellular localization. Methods 77-78:92-103
-
(2015)
Methods
, vol.77
, Issue.78
, pp. 92-103
-
-
Bononi, A.1
Pinton, P.2
-
22
-
-
27844535741
-
Class reunion: PTEN joins the nuclear crew
-
Lian Z, Di Cristofano A (2005) Class reunion: PTEN joins the nuclear crew. Oncogene 24(50):7394-7400
-
(2005)
Oncogene
, vol.24
, Issue.50
, pp. 7394-7400
-
-
Lian, Z.1
Di Cristofano, A.2
-
23
-
-
84938512401
-
A new class of cancer-associated PTEN mutations defined by membrane translocation defects
-
Nguyen HN, Yang JM Jr, Rahdar M et al (2014) A new class of cancer-associated PTEN mutations defined by membrane translocation defects. Oncogene 34:3737-3743
-
(2014)
Oncogene
, vol.34
, pp. 3737-3743
-
-
Nguyen, H.N.1
Yang, J.M.2
Rahdar, M.3
-
24
-
-
0035966127
-
Phosphorylation of the PTEN tail acts as an inhibitory switch by preventing its recruitment into a protein complex
-
Vazquez F, Grossman SR, Takahashi Y et al (2001) Phosphorylation of the PTEN tail acts as an inhibitory switch by preventing its recruitment into a protein complex. J Biol Chem 276(52):48627-48630
-
(2001)
J Biol Chem
, vol.276
, Issue.52
, pp. 48627-48630
-
-
Vazquez, F.1
Grossman, S.R.2
Takahashi, Y.3
-
25
-
-
33845977965
-
Ubiquitination regulates PTEN nuclear import and tumor suppression
-
Trotman LC, Wang X, Alimonti A et al (2007) Ubiquitination regulates PTEN nuclear import and tumor suppression. Cell 128(1):141-156
-
(2007)
Cell
, vol.128
, Issue.1
, pp. 141-156
-
-
Trotman, L.C.1
Wang, X.2
Alimonti, A.3
-
26
-
-
84904049059
-
Galectin-3 and PTEN expression in pancreatic ductal adenocarcinoma, pancreatic neuroendocrine neoplasms and gastrointestinal tumors on fine-needle aspiration cytology
-
Jiang K, Lawson D, Cohen C et al (2014) Galectin-3 and PTEN expression in pancreatic ductal adenocarcinoma, pancreatic neuroendocrine neoplasms and gastrointestinal tumors on fine-needle aspiration cytology. Acta Cytol 58(3):281-287
-
(2014)
Acta Cytol
, vol.58
, Issue.3
, pp. 281-287
-
-
Jiang, K.1
Lawson, D.2
Cohen, C.3
-
27
-
-
0034616634
-
Altered PTEN expression as a diagnostic marker for the earliest endometrial precancers
-
Mutter GL, Lin MC, Fitzgerald JT et al (2000) Altered PTEN expression as a diagnostic marker for the earliest endometrial precancers. J Natl Cancer Inst 92(11):924-930
-
(2000)
J Natl Cancer Inst
, vol.92
, Issue.11
, pp. 924-930
-
-
Mutter, G.L.1
Lin, M.C.2
Fitzgerald, J.T.3
-
28
-
-
84878114129
-
Loss of phosphatase and tensin homolog expression is associated with recurrence and poor prognosis in patients with pancreatic ductal adenocarcinoma
-
Foo WC, Rashid A, Wang H et al (2013) Loss of phosphatase and tensin homolog expression is associated with recurrence and poor prognosis in patients with pancreatic ductal adenocarcinoma. Hum Pathol 44(6):1024-1030
-
(2013)
Hum Pathol
, vol.44
, Issue.6
, pp. 1024-1030
-
-
Foo, W.C.1
Rashid, A.2
Wang, H.3
-
29
-
-
63049094489
-
Inactivation of p53 and Pten promotes invasive bladder cancer
-
Puzio-Kuter AM, Castillo-Martin M, Kinkade CW et al (2009) Inactivation of p53 and Pten promotes invasive bladder cancer. Genes Dev 23(6):675-680
-
(2009)
Genes Dev
, vol.23
, Issue.6
, pp. 675-680
-
-
Puzio-Kuter, A.M.1
Castillo-Martin, M.2
Kinkade, C.W.3
-
30
-
-
84904721750
-
The PI3K/AKT/mTOR pathway is activated in gastric cancer with potential prognostic and predictive significance
-
Tapia O, Riquelme I, Leal P et al (2014) The PI3K/AKT/mTOR pathway is activated in gastric cancer with potential prognostic and predictive significance. Virchows Arch 465(1):25-33
-
(2014)
Virchows Arch
, vol.465
, Issue.1
, pp. 25-33
-
-
Tapia, O.1
Riquelme, I.2
Leal, P.3
-
31
-
-
84856679750
-
Pathologic scoring of PTEN immunohistochemistry in endometrial carcinoma is highly reproducible
-
Garg K, Broaddus RR, Soslow RA et al (2012) Pathologic scoring of PTEN immunohistochemistry in endometrial carcinoma is highly reproducible. Int J Gynecol Pathol 31(1):48-56
-
(2012)
Int J Gynecol Pathol
, vol.31
, Issue.1
, pp. 48-56
-
-
Garg, K.1
Broaddus, R.R.2
Soslow, R.A.3
|