NGS-based reverse genetic screen for common embryonic lethal mutations compromising fertility in livestock

Genome Research

Volumn 26, Issue 10, 2016, Pages 1333-1341

  Charlier, Carole ^a,d   Li, Wanbo ^b,d   Harland, Chad ^a,c   Littlejohn, Mathew ^c   Coppieters, Wouter ^a   Creagh, Frances ^c   Davis, Steve ^c   Druet, Tom ^a   Faux, Pierre ^a   Guillaume, François ^a   Karim, Latifa ^a   Keehan, Mike ^c   Kadri, Naveen Kumar ^a   Tamma, Nico ^a   Spelman, Richard ^c   Georges, Michel ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b JIANGXI AGRICULTURAL UNIVERSITY   (China)

^c LIVESTOCK IMPROVEMENT CORPORATION   (New Zealand)

^d Evolution NT   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CONTROLLED STUDY; DAIRY CATTLE; EMBRYO; EXOME; FERTILITY; FRAMESHIFT MUTATION; GENE FREQUENCY; GENE MUTATION; GENETIC SCREENING; GENETIC VARIABILITY; GENOTYPE; HOMOZYGOTE; LETHAL MUTANT; LIVESTOCK; LOSS OF FUNCTION MUTATION; MISSENSE MUTATION; MUTATIONAL LOAD; NEXT GENERATION SEQUENCING; NONHUMAN; PRIORITY JOURNAL; REVERSE GENETICS; ANIMAL; BOVINE; DNA SEQUENCE; EMBRYOLOGY; GENETICS; HETEROZYGOTE; HIGH THROUGHPUT SEQUENCING; LETHAL GENE; MUTATION; PHYSIOLOGY; PROCEDURES;

ANIMALS; CATTLE; FERTILITY; GENES, LETHAL; GENETIC TESTING; HETEROZYGOTE; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HOMOZYGOTE; MUTATION; REVERSE GENETICS; SEQUENCE ANALYSIS, DNA;

EID: 84989901533     PISSN: 10889051     EISSN: 15495469     Source Type: Journal    
DOI: 10.1101/gr.207076.116     Document Type: Article

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