Bioconjugated manganese dioxide nanoparticles enhance chemotherapy response by priming tumor-Associated macrophages toward m1-like phenotype and attenuating tumor hypoxia

ACS Nano

Volumn 10, Issue 1, 2016, Pages 633-647

  Song, Manli ^a   Liu, Ting ^a   Shi, Changrong ^a   Zhang, Xiangzhong ^a   Chen, Xiaoyuan ^b  

^a XIAMEN UNIVERSITY   (China)

^b NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING   (United States)

Author keywords

Chemotherapy response; Hyaluronic acid (HA); Hypoxia; Manganese dioxide (MNO2); Mannose receptor; Tumor associated macrophages (TAMs)

Indexed keywords

CELL ENGINEERING; CELL PROLIFERATION; CHEMOTHERAPY; ENDOTHELIAL CELLS; HYALURONIC ACID; MACROPHAGES; MAGNETIC RESONANCE IMAGING; MANGANESE; MANGANESE OXIDE; NANOPARTICLES; ORGANIC ACIDS; SURFACE DIFFUSION; TISSUE;

CHEMOTHERAPY RESPONSE; HYPOXIA; MANGANESE DIOXIDE; MANNOSE RECEPTORS; TUMOR ASSOCIATED MACROPHAGES;

TUMORS;

ANTINEOPLASTIC AGENT; DOXORUBICIN; HIF1A PROTEIN, MOUSE; HYALURONIC ACID; HYDROGEN PEROXIDE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LIPOPOLYSACCHARIDE; MANGANESE DERIVATIVE; MANGANESE DIOXIDE; NANOPARTICLE; OXIDE;

ANIMAL; BAGG ALBINO MOUSE; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECTS; FEMALE; GENE EXPRESSION; GENETICS; HYPOXIA; MACROPHAGE; MAMMARY NEOPLASMS, EXPERIMENTAL; METABOLISM; MOUSE; NEOVASCULARIZATION, PATHOLOGIC; PATHOLOGY; PHENOTYPE; TUMOR CELL LINE; UDDER;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; DOXORUBICIN; FEMALE; GENE EXPRESSION; HYALURONIC ACID; HYDROGEN PEROXIDE; HYPOXIA; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LIPOPOLYSACCHARIDES; MACROPHAGES; MAMMARY GLANDS, ANIMAL; MAMMARY NEOPLASMS, EXPERIMENTAL; MANGANESE COMPOUNDS; MICE; MICE, INBRED BALB C; NANOPARTICLES; NEOVASCULARIZATION, PATHOLOGIC; OXIDES; PHENOTYPE;

EID: 84989875792     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/acsnano.5b06779     Document Type: Article

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