메뉴 건너뛰기




Volumn 18, Issue 10, 2016, Pages 1011-1019

Oncologists' and cancer patients' views on whole-exome sequencing and incidental findings: Results from the CanSeq study

Author keywords

cancer; incidental findings; return of results; sequencing

Indexed keywords

ADULT; ARTICLE; CANCER PATIENT; CANCER PROGNOSIS; CANCER RISK; CANCER SUSCEPTIBILITY; COLORECTAL CANCER; FEMALE; GENE SEQUENCE; GENETIC SCREENING; GERMLINE MUTATION; HUMAN; INCIDENTAL FINDING; LUNG CANCER; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; ONCOLOGIST; PATIENT ATTITUDE; PROSPECTIVE STUDY; AGED; EXOME; GENETIC PREDISPOSITION; GENETICS; HIGH THROUGHPUT SEQUENCING; HUMAN GENOME; NEOPLASMS; PATHOPHYSIOLOGY; PROGNOSIS;

EID: 84989856761     PISSN: 10983600     EISSN: 15300366     Source Type: Journal    
DOI: 10.1038/gim.2015.207     Document Type: Article
Times cited : (108)

References (41)
  • 1
    • 84880535720 scopus 로고    scopus 로고
    • ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing
    • American College of Medical Genetics and Genomics.
    • Green RC, Berg JS, Grody WW, et al.; American College of Medical Genetics and Genomics. ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing. Genet Med 2013;15:565-574.
    • (2013) Genet Med , vol.15 , pp. 565-574
    • Green, R.C.1    Berg, J.S.2    Grody, W.W.3
  • 2
    • 84947279527 scopus 로고    scopus 로고
    • American Society of Clinical Oncology Policy Statement Update: Genetic and genomic testing for cancer susceptibility
    • e-pub ahead of print 31 August
    • Robson ME, Bradbury AR, Arun B, et al. American Society of Clinical Oncology Policy Statement Update: genetic and genomic testing for cancer susceptibility. J Clin Oncol e-pub ahead of print 31 August 2015.
    • (2015) J Clin Oncol
    • Robson, M.E.1    Bradbury, A.R.2    Arun, B.3
  • 3
    • 0037162115 scopus 로고    scopus 로고
    • Risk-reducing salpingooophorectomy in women with a BRCA1 or BRCA2 mutation
    • Kauff ND, Satagopan JM, Robson ME, et al. Risk-reducing salpingooophorectomy in women with a BRCA1 or BRCA2 mutation. N Engl J Med 2002;346:1609-1615.
    • (2002) N Engl J Med. , vol.346 , pp. 1609-1615
    • Kauff, N.D.1    Satagopan, J.M.2    Robson, M.E.3
  • 4
    • 77956193440 scopus 로고    scopus 로고
    • Association of risk-reducing surgery in BRCA1 or BRCA2 mutation carriers with cancer risk and mortality
    • Domchek SM, Friebel TM, Singer CF, et al. Association of risk-reducing surgery in BRCA1 or BRCA2 mutation carriers with cancer risk and mortality. JAMA 2010;304:967-975.
    • (2010) JAMA , vol.304 , pp. 967-975
    • Domchek, S.M.1    Friebel, T.M.2    Singer, C.F.3
  • 5
    • 0141940150 scopus 로고    scopus 로고
    • Early malignant progression of hereditary medullary thyroid cancer
    • Machens A, Niccoli-Sire P, Hoegel J, et al. Early malignant progression of hereditary medullary thyroid cancer. N Engl J Med 2003;349:1517-1525.
    • (2003) N Engl J Med , vol.349 , pp. 1517-1525
    • Machens, A.1    Niccoli-Sire, P.2    Hoegel, J.3
  • 6
    • 0034011564 scopus 로고    scopus 로고
    • Controlled 15-year trial on screening for colorectal cancer in families with hereditary nonpolyposis colorectal cancer
    • Järvinen HJ, Aarnio M, Mustonen H, et al. Controlled 15-year trial on screening for colorectal cancer in families with hereditary nonpolyposis colorectal cancer. Gastroenterology 2000;118:829-834.
    • (2000) Gastroenterology , vol.118 , pp. 829-834
    • Järvinen, H.J.1    Aarnio, M.2    Mustonen, H.3
  • 7
    • 26844503270 scopus 로고    scopus 로고
    • Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer
    • Herceptin Adjuvant (HERA) Trial Study Team.
    • Piccart-Gebhart MJ, Procter M, Leyland-Jones B, et al.; Herceptin Adjuvant (HERA) Trial Study Team. Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer. N Engl J Med 2005;353:1659-1672.
    • (2005) N Engl J Med , vol.353 , pp. 1659-1672
    • Piccart-Gebhart, M.J.1    Procter, M.2    Leyland-Jones, B.3
  • 8
    • 0035810147 scopus 로고    scopus 로고
    • Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
    • Druker BJ, Talpaz M, Resta DJ, et al. Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N Engl J Med 2001;344:1031-1037.
    • (2001) N Engl J Med , vol.344 , pp. 1031-1037
    • Druker, B.J.1    Talpaz, M.2    Resta, D.J.3
  • 9
    • 77956030786 scopus 로고    scopus 로고
    • Inhibition of mutated, activated BRAF in metastatic melanoma
    • Flaherty KT, Puzanov I, Kim KB, et al. Inhibition of mutated, activated BRAF in metastatic melanoma. N Engl J Med 2010;363:809-819.
    • (2010) N Engl J Med , vol.363 , pp. 809-819
    • Flaherty, K.T.1    Puzanov, I.2    Kim, K.B.3
  • 10
    • 69949162760 scopus 로고    scopus 로고
    • Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
    • Mok TS, Wu YL, Thongprasert S, et al. Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma. N Engl J Med 2009;361:947-957.
    • (2009) N Engl J Med , vol.361 , pp. 947-957
    • Mok, T.S.1    Wu, Y.L.2    Thongprasert, S.3
  • 11
    • 84908086036 scopus 로고    scopus 로고
    • Prospective enterprise-level molecular genotyping of a cohort of cancer patients
    • MacConaill LE, Garcia E, Shivdasani P, et al. Prospective enterprise-level molecular genotyping of a cohort of cancer patients. J Mol Diagn 2014;16:660-672.
    • (2014) J Mol Diagn , vol.16 , pp. 660-672
    • MacConaill, L.E.1    Garcia, E.2    Shivdasani, P.3
  • 12
    • 84928105158 scopus 로고    scopus 로고
    • Memorial sloan kettering-integrated mutation profiling of actionable cancer targets (msk-impact): A hybridization capture-based next-generation sequencing clinical assay for solid tumor molecular oncology
    • Cheng DT, Mitchell TN, Zehir A, et al. Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT): a hybridization capture-based next-generation sequencing clinical assay for solid tumor molecular oncology. J Mol Diagn 2015;17:251-264.
    • (2015) J Mol Diagn , vol.17 , pp. 251-264
    • Cheng, D.T.1    Mitchell, T.N.2    Zehir, A.3
  • 13
    • 84880467544 scopus 로고    scopus 로고
    • Clinical analysis and interpretation of cancer genome data
    • Van Allen EM, Wagle N, Levy MA. Clinical analysis and interpretation of cancer genome data. J Clin Oncol 2013;31:1825-1833.
    • (2013) J Clin Oncol , vol.31 , pp. 1825-1833
    • Van Allen, E.M.1    Wagle, N.2    Levy, M.A.3
  • 14
    • 82655184653 scopus 로고    scopus 로고
    • Personalized oncology through integrative high-Throughput sequencing: A pilot study
    • Roychowdhury S, Iyer MK, Robinson DR, et al. Personalized oncology through integrative high-Throughput sequencing: a pilot study. Sci Transl Med 2011;3:111ra121.
    • (2011) Sci Transl Med , vol.3 , pp. 111ra121
    • Roychowdhury, S.1    Iyer, M.K.2    Robinson, D.R.3
  • 17
    • 79952325539 scopus 로고    scopus 로고
    • Confidence of primary care physicians in their ability to carry out basic medical genetic tasks-A European survey in five countries-part 1
    • Nippert I, Harris HJ, Julian-Reynier C, et al. Confidence of primary care physicians in their ability to carry out basic medical genetic tasks-A European survey in five countries-part 1. J Community Genet 2011;2:1-11.
    • (2011) J Community Genet , vol.2 , pp. 1-11
    • Nippert, I.1    Harris, H.J.2    Julian-Reynier, C.3
  • 18
    • 3442895722 scopus 로고    scopus 로고
    • Genetic information leaflets: Influencing attitudes towards genetic testing
    • Michie S, di Lorenzo E, Lane R, Armstrong K, Sanderson S. Genetic information leaflets: influencing attitudes towards genetic testing. Genet Med 2004;6:219-225.
    • (2004) Genet Med , vol.6 , pp. 219-225
    • Michie, S.1    Di Lorenzo, E.2    Lane, R.3    Armstrong, K.4    Sanderson, S.5
  • 19
    • 18744366697 scopus 로고    scopus 로고
    • The effects of a genetic information leaflet on public attitudes towards genetic testing
    • Sanderson SC, Wardle J, Michie S. The effects of a genetic information leaflet on public attitudes towards genetic testing. Public Underst Sci 2005;14:213-224.
    • (2005) Public Underst Sci , vol.14 , pp. 213-224
    • Sanderson, S.C.1    Wardle, J.2    Michie, S.3
  • 20
    • 1942466503 scopus 로고    scopus 로고
    • Racial and ethnic variations in knowledge and attitudes about genetic testing
    • Singer E, Antonucci T, Van Hoewyk J. Racial and ethnic variations in knowledge and attitudes about genetic testing. Genet Test 2004;8:31-43.
    • (2004) Genet Test , vol.8 , pp. 31-43
    • Singer, E.1    Antonucci, T.2    Van Hoewyk, J.3
  • 21
    • 0032809485 scopus 로고    scopus 로고
    • The genetic knowledge index: Developing a standard measure of genetic knowledge
    • Furr LA, Kelly SE. The Genetic Knowledge Index: developing a standard measure of genetic knowledge. Genet Test 1999;3:193-199.
    • (1999) Genet Test , vol.3 , pp. 193-199
    • Furr, L.A.1    Kelly, S.E.2
  • 23
    • 42449165070 scopus 로고    scopus 로고
    • Validation of screening questions for limited health literacy in a large VA outpatient population
    • Chew LD, Griffin JM, Partin MR, et al. Validation of screening questions for limited health literacy in a large VA outpatient population. J Gen Intern Med. 2008;23:561-566.
    • (2008) J Gen Intern Med. , vol.23 , pp. 561-566
    • Chew, L.D.1    Griffin, J.M.2    Partin, M.R.3
  • 24
    • 0020396015 scopus 로고
    • Toxicity and response criteria of the Eastern Cooperative Oncology Group
    • Oken MM, Creech RH, Tormey DC, et al. Toxicity and response criteria of the Eastern Cooperative Oncology Group. Am J Clin Oncol 1982;5:649-655.
    • (1982) Am J Clin Oncol , vol.5 , pp. 649-655
    • Oken, M.M.1    Creech, R.H.2    Tormey, D.C.3
  • 25
    • 20644435368 scopus 로고    scopus 로고
    • Patient online self-reporting of toxicity symptoms during chemotherapy
    • Basch E, Artz D, Dulko D, et al. Patient online self-reporting of toxicity symptoms during chemotherapy. J Clin Oncol 2005;23:3552-3561.
    • (2005) J Clin Oncol , vol.23 , pp. 3552-3561
    • Basch, E.1    Artz, D.2    Dulko, D.3
  • 26
    • 0027417437 scopus 로고
    • The European Organization for Research and Treatment of Cancer QLQ-C30: A quality-of-life instrument for use in international clinical trials in oncology
    • Aaronson NK, Ahmedzai S, Bergman B, et al. The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst 1993;85:365-376.
    • (1993) J Natl Cancer Inst , vol.85 , pp. 365-376
    • Aaronson, N.K.1    Ahmedzai, S.2    Bergman, B.3
  • 27
    • 0030902761 scopus 로고    scopus 로고
    • Information needs and decisional preferences in women with breast cancer
    • Degner LF, Kristjanson LJ, Bowman D, et al. Information needs and decisional preferences in women with breast cancer. JAMA 1997;277:1485-1492.
    • (1997) JAMA , vol.277 , pp. 1485-1492
    • Degner, L.F.1    Kristjanson, L.J.2    Bowman, D.3
  • 28
    • 1642420994 scopus 로고    scopus 로고
    • A modified poisson regression approach to prospective studies with binary data
    • Zou G. A modified poisson regression approach to prospective studies with binary data. Am J Epidemiol 2004;159:702-706.
    • (2004) Am J Epidemiol , vol.159 , pp. 702-706
    • Zou, G.1
  • 30
    • 84989814100 scopus 로고    scopus 로고
    • National comprehensive cancer network clinical practice guidelines in oncology (nccn guidelines®) colon cancer version 2.2015
    • Accessed 16 September, 2015
    • National Comprehensive Cancer Network Clinical Practice Guidelines in Oncology (NCCN Guidelines®) Colon Cancer Version 2.2015. J Natl Compr Canc Netw 2014:1-143. http://www.nccn.org/professionals/physician-gls/pdf/colon.pdf. Accessed 16 September, 2015.
    • (2014) J Natl Compr Canc Netw , pp. 1-143
  • 31
    • 84902148239 scopus 로고    scopus 로고
    • Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine
    • Van Allen EM, Wagle N, Stojanov P, et al. Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine. Nat Med 2014;20:682-688.
    • (2014) Nat Med , vol.20 , pp. 682-688
    • Van Allen, E.M.1    Wagle, N.2    Stojanov, P.3
  • 32
    • 84887498253 scopus 로고    scopus 로고
    • Experiences and attitudes of genome investigators regarding return of individual genetic test results
    • Ramoni RB, McGuire AL, Robinson JO, Morley DS, Plon SE, Joffe S. Experiences and attitudes of genome investigators regarding return of individual genetic test results. Genet Med 2013;15:882-887.
    • (2013) Genet Med , vol.15 , pp. 882-887
    • Ramoni, R.B.1    McGuire, A.L.2    Robinson, J.O.3    Morley, D.S.4    Plon, S.E.5    Joffe, S.6
  • 33
    • 84925387745 scopus 로고    scopus 로고
    • The right to know and genetic testing
    • Sheehan M. The right to know and genetic testing. J Med Ethics 2015;41: 287-288.
    • (2015) J Med Ethics , vol.41 , pp. 287-288
    • Sheehan, M.1
  • 34
    • 84877645710 scopus 로고    scopus 로고
    • Pharmacogenetics in clinical practice: How far have we come and where are we going?
    • Johnson JA Pharmacogenetics in clinical practice: how far have we come and where are we going?. Pharmacogenomics 2013;14:835-843
    • (2013) Pharmacogenomics , vol.14 , pp. 835-843
    • Johnson, J.A.1
  • 35
    • 82955233708 scopus 로고    scopus 로고
    • Personalizing medicine with clinical pharmacogenetics
    • Scott SA. Personalizing medicine with clinical pharmacogenetics. Genet Med 2011;13:987-995.
    • (2011) Genet Med , vol.13 , pp. 987-995
    • Scott, S.A.1
  • 36
    • 79951809968 scopus 로고    scopus 로고
    • Clinical Pharmacogenetics Implementation Consortium guidelines for thiopurine methyltransferase genotype and thiopurine dosing
    • Clinical Pharmacogenetics Implementation Consortium.
    • Relling MV, Gardner EE, Sandborn WJ, et al.; Clinical Pharmacogenetics Implementation Consortium. Clinical Pharmacogenetics Implementation Consortium guidelines for thiopurine methyltransferase genotype and thiopurine dosing. Clin Pharmacol Ther 2011;89:387-391.
    • (2011) Clin Pharmacol Ther , vol.89 , pp. 387-391
    • Relling, M.V.1    Gardner, E.E.2    Sandborn, W.J.3
  • 37
    • 84940937257 scopus 로고    scopus 로고
    • Center for Drug Evaluation, Research. Accessed 23 January 2015
    • Center for Drug Evaluation, Research. Genomics-Table of Pharmacogenomic Biomarkers in Drug Labeling. http://www.fda.gov/Drugs/ScienceResearch/ResearchAreas/Pharmacogenetics/ucm083378.htm. Accessed 23 January 2015.
    • Genomics-Table of Pharmacogenomic Biomarkers in Drug Labeling
  • 38
    • 84905815773 scopus 로고    scopus 로고
    • Clinical tumor sequencing: An incidental casualty of the American College of Medical Genetics and Genomics recommendations for reporting of incidental findings
    • Parsons DW, Roy A, Plon SE, Roychowdhury S, Chinnaiyan AM. Clinical tumor sequencing: an incidental casualty of the American College of Medical Genetics and Genomics recommendations for reporting of incidental findings. J Clin Oncol 2014;32:2203-2205.
    • (2014) J Clin Oncol. , vol.32 , pp. 2203-2205
    • Parsons, D.W.1    Roy, A.2    Plon, S.E.3    Roychowdhury, S.4    Chinnaiyan, A.M.5
  • 39
    • 84947216680 scopus 로고    scopus 로고
    • Breast cancer experience of the molecular tumor board at the University of California, San Diego Moores Cancer Center
    • Parker BA, Schwaederlé M, Scur MD, et al. Breast cancer experience of the molecular tumor board at the University of California, San Diego Moores Cancer Center. J Oncol Pract 2015;11:442-449.
    • (2015) J Oncol Pract , vol.11 , pp. 442-449
    • Parker, B.A.1    Schwaederlé, M.2    Scur, M.D.3
  • 40
    • 3242763836 scopus 로고    scopus 로고
    • Effect of a computer-based decision aid on knowledge, perceptions, and intentions about genetic testing for breast cancer susceptibility: A randomized controlled trial
    • Green MJ, Peterson SK, Baker MW, et al. Effect of a computer-based decision aid on knowledge, perceptions, and intentions about genetic testing for breast cancer susceptibility: a randomized controlled trial. JAMA 2004;292: 442-452.
    • (2004) JAMA , vol.292 , pp. 442-452
    • Green, M.J.1    Peterson, S.K.2    Baker, M.W.3
  • 41
    • 77649208372 scopus 로고    scopus 로고
    • American Society of Clinical Oncology policy statement update: Genetic and genomic testing for cancer susceptibility
    • American College of Medical Genetics and Genomics.
    • Robson ME, Storm CD, Weitzel J, Wollins DS, Offit K; American College of Medical Genetics and Genomics. American Society of Clinical Oncology policy statement update: genetic and genomic testing for cancer susceptibility. J Clin Oncol 2010;28:893-901.
    • (2010) J Clin Oncol , vol.28 , pp. 893-901
    • Robson, M.E.1    Storm, C.D.2    Weitzel, J.3    Wollins, D.S.4    Offit, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.