CaCO3 nanoparticles as an ultra-sensitive tumor-pH-responsive nanoplatform enabling real-time drug release monitoring and cancer combination therapy

Biomaterials

Volumn 110, Issue , 2016, Pages 60-70

  Dong, Ziliang ^a   Feng, Liangzhu ^a   Zhu, Wenwen ^a   Sun, Xiaoqi ^a   Gao, Min ^a   Zhao, He ^b   Chao, Yu ^a   Liu, Zhuang ^a  

^a SOOCHOW UNIVERSITY   (China)

^b CHILDREN S HOSPITAL OF SOOCHOW UNIVERSITY   (China)

Author keywords

CaCO3 nanoparticle; Cancer combination therapy; MR imaging; pH sensitive; Real time monitoring

Indexed keywords

CALCIUM CARBONATE; CHEMOTHERAPY; DISEASES; DRUG PRODUCTS; MAGNETIC RESONANCE; MAGNETIC RESONANCE IMAGING; NANOMAGNETICS; NANOPARTICLES; PH; PHOTOSENSITIZERS; TUMORS;

CLINICAL TRANSLATION; COMBINATION THERAPY; FLUORESCENCE IMAGING; MR IMAGING; PH SENSITIVE; REAL TIME MONITORING; SIGNAL ENHANCEMENT; STIMULI-RESPONSIVE;

MANGANESE;

CALCIUM CARBONATE; DOXORUBICIN; MACROGOL; NANOPARTICLE; ANTINEOPLASTIC AGENT; ANTINEOPLASTIC ANTIBIOTIC; DRUG CARRIER; MACROGOL DERIVATIVE; PHOTOSENSITIZING AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG MONITORING; DRUG POTENTIATION; DRUG RELEASE; FEMALE; FLUORESCENCE IMAGING; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NEOPLASM; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PARTICLE SIZE; PH; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL; TRANSMISSION ELECTRON MICROSCOPY; TUMOR MICROENVIRONMENT; TUMOR MODEL; TUMOR VOLUME; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; METABOLISM;

ANTIBIOTICS, ANTINEOPLASTIC; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CALCIUM CARBONATE; DOXORUBICIN; DRUG CARRIERS; DRUG LIBERATION; DRUG MONITORING; DRUG SYNERGISM; HUMANS; HYDROGEN-ION CONCENTRATION; INJECTIONS, INTRAVENOUS; MAGNETIC RESONANCE IMAGING; NANOPARTICLES; NEOPLASMS; PHOTOSENSITIZING AGENTS; POLYETHYLENE GLYCOLS;

EID: 84989285248     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2016.09.025     Document Type: Article

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