DNA hypomethylation and its mediation in the effects of fine particulate air pollution on cardiovascular biomarkers: A randomized crossover trial

Environment International

Volumn 94, Issue , 2016, Pages 614-619

  Chen, Renjie ^a   Meng, Xia ^b   Zhao, Ang ^a   Wang, Cuicui ^a   Yang, Changyuan ^a   Li, Huichu ^a   Cai, Jing ^a   Zhao, Zhuohui ^a   Kan, Haidong ^a  

^a FUDAN UNIVERSITY   (China)

^b EMORY UNIVERSITY   (United States)

Author keywords

Air pollution; Cardiovascular biomarker; DNA methylation; Fine particulate matter; Mediation; Randomized controlled trial

Indexed keywords

AIR CLEANERS; AIR POLLUTION; ALKYLATION; DNA; GENES; METHYLATION; PARTICLES (PARTICULATE MATTER); STUDENTS;

DNA METHYLATION; FINE PARTICULATE MATTER; FINE PARTICULATE MATTER (PM2.5); INTERVENTION STUDIES; MEDIATION; MIXED-EFFECT MODELS; RANDOMIZED CONTROLLED TRIAL; SHORT-TERM EXPOSURE;

BIOMARKERS;

C REACTIVE PROTEIN; CD40 LIGAND; DIPEPTIDYL CARBOXYPEPTIDASE; ENDOTHELIN 1; FIBRINOGEN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; PLASMINOGEN ACTIVATOR INHIBITOR 1; THROMBOPLASTIN; TOLL LIKE RECEPTOR 2; TUMOR NECROSIS FACTOR; BIOLOGICAL MARKER;

ATMOSPHERIC POLLUTION; BIOMARKER; CARDIOVASCULAR DISEASE; DNA; GENE; METHYLATION; PARTICULATE MATTER; POLLUTION EXPOSURE;

ACE GENE; ADULT; AIR FILTER; AIR POLLUTION CONTROL; AIR PURIFICATION; ALU SEQUENCE; ARTICLE; CD40LG GENE; CHINESE; COLLEGE STUDENT; CONTROLLED STUDY; DNA METHYLATION; DOUBLE BLIND PROCEDURE; EDN1 GENE; F3 GENE; FEMALE; HUMAN; ICAM1 GENE; IL6 GENE; INDOOR AIR POLLUTION; LONG INTERSPERSED NUCLEOTIDE ELEMENT 1; LONG INTERSPERSED REPEAT; MALE; MCP1 GENE; NORMAL HUMAN; PARTICULATE MATTER; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SERPINE 1 GENE; TLR2 GENE; TNF GENE; ANALYSIS; CHINA; CROSSOVER PROCEDURE; ENVIRONMENTAL EXPOSURE; GENETICS;

CHINA; SHANGHAI;

AIR FILTERS; BIOMARKERS; CHINA; CROSS-OVER STUDIES; DNA METHYLATION; DOUBLE-BLIND METHOD; ENVIRONMENTAL EXPOSURE; HUMANS; LONG INTERSPERSED NUCLEOTIDE ELEMENTS; PARTICULATE MATTER;

EID: 84989241799     PISSN: 01604120     EISSN: 18736750     Source Type: Journal    
DOI: 10.1016/j.envint.2016.06.026     Document Type: Article

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