Cardiopulmonary benefits of reducing indoor particles of outdoor origin: A randomized, double-blind crossover trial of air purifiers

Journal of the American College of Cardiology

Volumn 65, Issue 21, 2015, Pages 2279-2287

  Chen, Renjie ^a   Zhao, Ang ^a   Chen, Honglei ^b   Zhao, Zhuohui ^a   Cai, Jing ^a   Wang, Cuicui ^a   Yang, Changyuan ^a   Li, Huichu ^a   Xu, Xiaohui ^c   Ha, Sandie ^c   Li, Tiantian ^d   Kan, Haidong ^a  

^a FUDAN UNIVERSITY   (China)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^d CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

Author keywords

air pollution; air purification; cardiovascular health; intervention; pulmonary health; randomized controlled trial

Indexed keywords

BIOLOGICAL MARKER; CD40 LIGAND; INTERLEUKIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; MYELOPEROXIDASE; NITROUS OXIDE; PARTICULATE MATTER;

ADULT; AIR FILTER; AIR MONITOR; AIR PARTICLE CONTROL; AIR POLLUTION; AMBIENT AIR; ARTICLE; BLOOD CLOTTING; CARDIOPULMONARY FUNCTION; CHINA; CHINESE; COLLEGE STUDENT; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CROSSOVER PROCEDURE; DIASTOLIC BLOOD PRESSURE; DOUBLE BLIND PROCEDURE; FEMALE; GEOMETRY; HUMAN; HUMAN EXPERIMENT; INFLAMMATION; LUNG FUNCTION; MALE; NORMAL HUMAN; OUTCOME VARIABLE; PARTICULATE MATTER; PRIORITY JOURNAL; PURIFICATION; RANDOMIZED CONTROLLED TRIAL; RISK BENEFIT ANALYSIS; RISK REDUCTION; SHAM PROCEDURE; SYSTOLIC BLOOD PRESSURE; VASOCONSTRICTION; YOUNG ADULT; ADVERSE EFFECTS; BLOOD; CARDIOVASCULAR DISEASE; CITY; INDOOR AIR POLLUTION; LUNG FUNCTION TEST; PREVENTION AND CONTROL; STATISTICS AND NUMERICAL DATA;

ADULT; AIR FILTERS; AIR POLLUTION, INDOOR; BIOLOGICAL MARKERS; CARDIOVASCULAR DISEASES; CHINA; CITIES; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; FEMALE; HEALTHY VOLUNTEERS; HUMANS; MALE; PARTICULATE MATTER; RESPIRATORY FUNCTION TESTS; YOUNG ADULT;

EID: 84930028348     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2015.03.553     Document Type: Article

References (28)

1. R.D. Brook, S. Rajagopalan, C.A. Pope 3rd for the American Heart Association Council on Epidemiology and Prevention, Council on the Kidney in Cardiovascular Disease, and Council on Nutrition, Physical Activity and Metabolism Particulate matter air pollution and cardiovascular disease: an update to the scientific statement from the American Heart Association Circulation 121 2010 2331 2378
2. C.A. Pope 3rd, and D.W. Dockery Health effects of fine particulate air pollution: lines that connect J Air Waste Manag Assoc 56 2006 709 742
3. X. Meng, C. Wang, D. Cao, C.-M. Wong, and H. Kan Short-term effect of ambient air pollution on COPD mortality in four Chinese cities Atmos Environ 77 2013 149 154
4. H. Mustafic, P. Jabre, and C. Caussin Main air pollutants and myocardial infarction: a systematic review and meta-analysis JAMA 307 2012 713 721
5. A.S.V. Shah, J.P. Langrish, and H. Nair Global association of air pollution and heart failure: a systematic review and meta-analysis Lancet 382 2013 1039 1048
6. M.S. Link, H. Luttmann-Gibson, and J. Schwartz Acute exposure to air pollution triggers atrial fibrillation J Am Coll Cardiol 62 2013 816 825
7. K.B. Ensor, L.H. Raun, and D. Persse A case-crossover analysis of out-of-hospital cardiac arrest and air pollution Circulation 127 2013 1192 1199
8. G.A. Wellenius, M.R. Burger, and B.A. Coull Ambient air pollution and the risk of acute ischemic stroke Arch Intern Med 172 2012 229 234
9. S.S. Lim, T. Vos, and A.D. Flaxman A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010 [published corrections appear in Lancet 2013;381:628 and Lancet 2013;381:1276] Lancet 380 2012 2224 2260
10. China's Ministry of Environmental Protection Exposure Factors Handbook of Chinese population: Adult Edition 2013 China Environmental Science Press Beijing, China
11. R.W. Allen, C. Carlsten, and B. Karlen An air filter intervention study of endothelial function among healthy adults in a woodsmoke-impacted community Am J Respir Crit Care Med 183 2011 1222 1230
12. E.V. Bräuner, L. Forchhammer, and P. Møller Indoor particles affect vascular function in the aged: an air filtration-based intervention study Am J Respir Crit Care Med 177 2008 419 425
13. D.G. Karottki, M. Spilak, and M. Frederiksen An indoor air filtration study in homes of elderly: cardiovascular and respiratory effects of exposure to particulate matter Environ Health 12 2013 116
14. S. Weichenthal, G. Mallach, and R. Kulka A randomized double-blind crossover study of indoor air filtration and acute changes in cardiorespiratory health in a First Nations community Indoor Air 23 2013 175 184
15. R. Chen, Z. Zhao, and Q. Sun Size-fractionated particulate air pollution and circulating biomarkers of inflammation, coagulation, and vasoconstriction in a panel of young adults Epidemiology 26 2015 328 336
16. S. Li, G. Williams, B. Jalaludin, and P. Baker Panel studies of air pollution on children's lung function and respiratory symptoms: a literature review J Asthma 49 2012 895 910
17. S. Wu, F. Deng, and Y. Hao Chemical constituents of fine particulate air pollution and pulmonary function in healthy adults: the Healthy Volunteer Natural Relocation study J Hazard Mater 260 2013 183 191
18. S.J. Head, S. Kaul, A.J. Bogers, and A.P. Kappetein Non-inferiority study design: lessons to be learned from cardiovascular trials Eur Heart J 33 2012 1318 1324
19. C.L. Phillips, R.R. Grunstein, and M.A. Darendeliler Health outcomes of continuous positive airway pressure versus oral appliance treatment for obstructive sleep apnea: a randomized controlled trial Am J Respir Crit Care Med 187 2013 879 887
20. J. Zhang, T. Zhu, and H. Kipen Cardiorespiratory biomarker responses in healthy young adults to drastic air quality changes surrounding the 2008 Beijing Olympics Res Rep Health Eff Inst 2013 5 174
21. K. Berhane, Y. Zhang, and W.S. Linn The effect of ambient air pollution on exhaled nitric oxide in the Children's Health Study Eur Respir J 37 2011 1029 1036
22. R. Ruckerl, R.P. Phipps, and A. Schneider Ultrafine particles and platelet activation in patients with coronary heart disease: results from a prospective panel study Part Fibre Toxicol 4 2007 1
23. L. Calderón-Garciduenas, R. Vincent, and A. Mora-Tiscareño Elevated plasma endothelin-1 and pulmonary arterial pressure in children exposed to air pollution Environ Health Perspect 115 2007 1248 1253
24. A. Peretz, J.H. Sullivan, and D.F. Leotta Diesel exhaust inhalation elicits acute vasoconstriction in vivo Environ Health Perspect 116 2008 937 942
25. L. Liu, R. Poon, and L. Chen Acute effects of air pollution on pulmonary function, airway inflammation, and oxidative stress in asthmatic children Environ Health Perspect 117 2009 668 674
26. A.A. Baccarelli, Y. Zheng, and X. Zhang Air pollution exposure and lung function in highly exposed subjects in Beijing, China: a repeated-measure study Part Fibre Toxicol 11 2014 51
27. M.M. Patel, S.N. Chillrud, K.C. Deepti, J.M. Ross, and P.L. Kinney Traffic-related air pollutants and exhaled markers of airway inflammation and oxidative stress in New York City adolescents Environ Res 121 2013 71 78
28. B. Urch, F. Silverman, and P. Corey Acute blood pressure responses in healthy adults during controlled air pollution exposures Environ Health Perspect 113 2005 1052 1055