Change is not necessarily progress: Revision of the sepsis definition should be based on new scientific insights

American Journal of Respiratory and Critical Care Medicine

Volumn 194, Issue 1, 2016, Pages 16-18

  Cortes Puch, Irene ^a   Hartog, Christiane S ^b,c  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b Center for Sepsis Control and Care   (Germany)

^c JENA UNIVERSITY HOSPITAL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE ASSESSMENT; EDITORIAL; HUMAN; HYPOTENSION; MORTALITY; PRIORITY JOURNAL; SEPSIS; SEQUENTIAL ORGAN FAILURE ASSESSMENT SCORE; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME CRITERIA; CLASSIFICATION; MEDICAL RESEARCH;

BIOMEDICAL RESEARCH; HUMANS; SEPSIS;

EID: 84988891057     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201604-0734ED     Document Type: Editorial

References (13)

1. Bone RC, Balk RA, Cerra FB, Dellinger RP, Fein AM, Knaus WA, Schein RM, Sibbald WJ; The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Chest 1992;101:1644-1655.
2. Bone RC, Sprung CL, Sibbald WJ. Definitions for sepsis and organ failure. Crit Care Med 1992;20:724-726.
3. Levy MM, Fink MP, Marshall JC, Abraham E, Angus D, Cook D, Cohen J, Opal SM, Vincent JL, Ramsay G; SCCM/ESICM/ACCP/ATS/SIS. 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Crit Care Med 2003;31:1250-1256.
4. Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, Bellomo R, Bernard GR, Chiche JD, Coopersmith CM, et al. The third international consensus definitions for sepsis and septic shock (sepsis-3). JAMA 2016;315:801-810.
5. Seymour CW, Liu VX, Iwashyna TJ, Brunkhorst FM, Rea TD, Scherag A, Rubenfeld G, Kahn JM, Shankar-Hari M, Singer M, et al. Assessment of clinical criteria for sepsis: for the third international consensus definitions for sepsis and septic shock (sepsis-3). JAMA 2016;315: 762-774.
6. Shankar-Hari M, Phillips GS, Levy ML, Seymour CW, Liu VX, Deutschman CS, Angus DC, Rubenfeld GD, Singer M; Sepsis Definitions Task Force. Sepsis definitions task F: developing a new definition and assessing new clinical criteria for septic shock: for the third international consensus definitions for sepsis and septic shock (sepsis-3). JAMA 2016;315:775-787.
7. Suffredini AF, Munford RS. Novel therapies for septic shock over the past 4 decades. JAMA 2011;306:194-199.
8. Rhodes A, Phillips G, Beale R, Cecconi M, Chiche JD, De Backer D, Divatia J, Du B, Evans L, Ferrer R, et al. The surviving sepsis campaign bundles and outcome: results from the international multicentre prevalence study on sepsis (the impress study). Intensive Care Med 2015;41:1620-1628.
9. Ferrer R, Martin-Loeches I, Phillips G, Osborn TM, Townsend S, Dellinger RP, Artigas A, Schorr C, Levy MM. Empiric antibiotic treatment reduces mortality in severe sepsis and septic shock from the first hour: results from a guideline-based performance improvement program. Crit Care Med 2014;42:1749-1755.
10. Burrell AR, McLaws ML, Fullick M, Sullivan RB, Sindhusake D. SEPSIS KILLS: early intervention saves lives. Med J Aust 2016; 204:73.
11. Cheng AC, West TE, Limmathurotsakul D, Peacock SJ. Strategies to reduce mortality from bacterial sepsis in adults in developing countries. PLoS Med 2008;5:e175.
12. Machado FR, Salomão R, de Azevedo LC, Lisboa T, Filho RC; on behalf of the Latin American Sepsis Institute. Why LASI did not endorse the new definitions of sepsis published today in JAMA. Brazil: Instituto Latino Americano da Sepse; 2016 [accessed 2016 Apr 1]. Available from: http://ilas.org.br/upfiles/arquivos/statement-en.pdf
13. Simpson SQ. New sepsis criteria: A change we should not make. Chest 2016;149:1117-1118.