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Angewandte Chemie - International Edition

Volumn 55, Issue 43, 2016, Pages 13524-13528

A Macrocyclic Ruthenium(III) Complex Inhibits Angiogenesis with Down-Regulation of Vascular Endothelial Growth Factor Receptor-2 and Suppresses Tumor Growth In Vivo

(6) Kwong, Wai Lun a Lam, Kar Yee a Lok, Chun Nam a Lai, Yau Tsz a Lee, Pui Yan a Che, Chi Ming a,b

a UNIVERSITY OF HONG KONG (Hong Kong)

b UNIVERSITY OF HONG KONG (China)

Author keywords

angiogenesis; anti cancer; ruthenium; VEGFRs

Indexed keywords

CELL CULTURE; CELL ENGINEERING; DISEASES; ENDOTHELIAL CELLS; MAMMALS; RUTHENIUM; TUMORS;

ANGIOGENESIS; ANTI-CANCER; CANCER CELL LINES; RUTHENIUM COMPLEXES; RUTHENIUM COMPLEXES (III); TUMOR ANGIOGENESIS; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR; VEGFRS;

RUTHENIUM COMPOUNDS;

ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC AGENT; COORDINATION COMPOUND; KDR PROTEIN, HUMAN; MACROCYCLIC COMPOUND; RUTHENIUM; VASCULOTROPIN RECEPTOR 2;

ANIMAL; ANTAGONISTS AND INHIBITORS; CELL PROLIFERATION; CHEMISTRY; DOSE RESPONSE; DOWN REGULATION; DRUG EFFECT; DRUG SCREENING; EXPERIMENTAL MAMMARY NEOPLASM; FEMALE; HUMAN; METABOLISM; MOUSE; NEOVASCULARIZATION (PATHOLOGY); NUDE MOUSE; PATHOLOGY; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE; UMBILICAL VEIN ENDOTHELIAL CELL; ZEBRA FISH;

ANGIOGENESIS INHIBITORS; ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; COORDINATION COMPLEXES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MACROCYCLIC COMPOUNDS; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MICE, NUDE; NEOVASCULARIZATION, PATHOLOGIC; RUTHENIUM; STRUCTURE-ACTIVITY RELATIONSHIP; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2; ZEBRAFISH;

EID: 84988850792 PISSN: 14337851 EISSN: 15213773 Source Type: Journal
DOI: 10.1002/anie.201608094 Document Type: Article

Times cited : (24)

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