Vitamin D supplementation and the risk of colds in patients with asthma

American Journal of Respiratory and Critical Care Medicine

Volumn 193, Issue 6, 2016, Pages 634-641

  Denlinger, Loren C ^a   King, Tonya S ^b   Cardet, Juan Carlos ^c   Craig, Timothy ^b   Holguin, Fernando ^d   Jackson, Daniel J ^a   Kraft, Monica ^e   Peters, Stephen P ^f   Ross, Kristie ^g   Sumino, Kaharu ^h   Boushey, Homer A ⁱ   Jarjour, Nizar N ^a   Wechsler, Michael E ^j   Wenzel, Sally E ^d   Castro, Mario ^h   Avila, Pedro C ^k  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b PENN STATE COLLEGE OF MEDICINE   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^e DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f WAKE FOREST SCHOOL OF MEDICINE   (United States)

^g CASE WESTERN RESERVE UNIVERSITY   (United States)

^h WASHINGTON UNIVERSITY   (United States)

ⁱ UNIVERSITY OF CALIFORNIA   (United States)

^j DEPARTMENT OF MEDICINE   (United States)

^k NORTHWESTERN UNIVERSITY   (United States)

more..

Author keywords

Asthma; Upper respiratory tract infection; Vitamin D; WURSS 21

Indexed keywords

25 HYDROXYVITAMIN D; COLECALCIFEROL; CORTICOSTEROID; LEVALBUTEROL; METHACHOLINE; PLACEBO; PREDNISONE;

21 ITEM WISCONSIN UPPER RESPIRATORY SYMPTOM SURVEY; ADD ON THERAPY; AFRICAN AMERICAN; ARTICLE; ASTHMA; COMMON COLD SYMPTOM; CONTROLLED STUDY; CORTICOSTEROID THERAPY; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; LOADING DRUG DOSE; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY TRACT DISEASE ASSESSMENT; RISK FACTOR; SECONDARY ANALYSIS; TREATMENT DURATION; VITAMIN D DEFICIENCY; VITAMIN SUPPLEMENTATION; ADULT; COMORBIDITY; DIETARY SUPPLEMENT; RESPIRATORY TRACT INFECTIONS; RISK; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME;

ADULT; ASTHMA; CHOLECALCIFEROL; COMORBIDITY; DIETARY SUPPLEMENTS; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MALE; PROSPECTIVE STUDIES; RESPIRATORY TRACT INFECTIONS; RISK; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME; VITAMIN D DEFICIENCY;

EID: 84988697527     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201506-1169OC     Document Type: Article

References (27)

1. Ambrosioni J, Bridevaux PO, Wagner G, Mamin A, Kaiser L. Epidemiology of viral respiratory infections in a tertiary care centre in the era of molecular diagnosis, Geneva, Switzerland, 2011-2012. Clin Microbiol Infect 2014;20:O578-O584.
2. Holick MF. Photobiology of vitamin D. In: Feldman D, Pike JW, Adams JS, editors. Vitamin D. Vol. 1. London: Academic Press; 2011, p. 13-22.
3. Camargo CA Jr, Ingham T, Wickens K, Thadhani R, Silvers KM, Epton MJ, Town GI, Pattemore PK, Espinola JA, Crane J; New Zealand Asthma and Allergy Cohort Study Group. Cord-blood 25-hydroxyvitamin D levels and risk of respiratory infection, wheezing, and asthma. Pediatrics 2011;127:e180-e187.
4. Quraishi SA, Bittner EA, Christopher KB, Camargo CA Jr. Vitamin D status and community-acquired pneumonia: results from the third National Health and Nutrition Examination Survey. PLoS One 2013;8:e81120.
5. Brockman-Schneider RA, Pickles RJ, Gern JE. Effects of vitamin D on airway epithelial cell morphology and rhinovirus replication. PLoS One 2014;9:e86755.
6. Liu PT. The role of vitamin D in innate immunity: antimicrobial activity, oxidative stress and barrier function. In Feldman D, Pike JW, Adams JS, editors. Vitamin D. Vol. 2. London: Academic Press; 2011. p. 1777-1787.
7. Adorini L. Tolerogenic dendritic cells induced by vitamin D receptor ligands enhance regulatory T cells inhibiting autoimmune diabetes. Ann N Y Acad Sci 2003;987:258-261.
8. Vasiliou JE, Lui S, Walker SA, Chohan V, Xystrakis E, Bush A, Hawrylowicz CM, Saglani S, Lloyd CM. Vitamin D deficiency induces Th2 skewing and eosinophilia in neonatal allergic airways disease. Allergy 2014;69:1380-1389.
9. Adorini L. Control of adaptive immunity by vitamin D receptor agonists. In: Feldman D, Pike JW, Adams JS, editors. Vitamin D. Vol. 2. London: Academic Press; 2011. p. 1789-1809.
10. Urashima M, Segawa T, Okazaki M, Kurihara M, Wada Y, Ida H. Randomized trial of vitamin D supplementation to prevent seasonal influenza A in schoolchildren. Am J Clin Nutr 2010;91: 1255-1260.
11. Camargo CA Jr, Ganmaa D, Frazier AL, Kirchberg FF, Stuart JJ, Kleinman K, Sumberzul N, Rich-Edwards JW. Randomized trial of vitamin D supplementation and risk of acute respiratory infection in Mongolia. Pediatrics 2012;130:e561-e567.
12. Murdoch DR, Slow S, Chambers ST, Jennings LC, Stewart AW, Priest PC, Florkowski CM, Livesey JH, Camargo CA, Scragg R. Effect of vitamin D3 supplementation on upper respiratory tract infections in healthy adults: the VIDARIS randomized controlled trial. JAMA 2012;308:1333-1339.
13. Bergman P, Lindh AU, Björkhem-Bergman L, Lindh JD. Vitamin D and respiratory tract infections: a systematic review and meta-analysis of randomized controlled trials. PLoS One 2013;8:e65835.
14. Goodall EC, Granados AC, Luinstra K, Pullenayegum E, Coleman BL, Loeb M, Smieja M. Vitamin D3 and gargling for the prevention of upper respiratory tract infections: a randomized controlled trial. BMC Infect Dis 2014;14:273.
15. Corne JM, Marshall C, Smith S, Schreiber J, Sanderson G, Holgate ST, Johnston SL. Frequency, severity, and duration of rhinovirus infections in asthmatic and non-asthmatic individuals: a longitudinal cohort study. Lancet 2002;359:831-834.
16. Black PN, Scragg R. Relationship between serum 25-hydroxyvitamin D and pulmonary function in the Third National Health and Nutrition Examination Survey. Chest 2005;128:3792-3798.
17. Castro M, King TS, Kunselman SJ, Cabana MD, Denlinger L, Holguin F, Kazani SD, Moore WC, Moy J, Sorkness CA, et al.; National Heart, Lung, and Blood Institute?s AsthmaNet. Effect of vitamin D3 on asthma treatment failures in adults with symptomatic asthma and lower vitamin D levels: the VIDA randomized clinical trial. JAMA 2014;311:2083-2091.
18. Nicholson KG, Kent J, Ireland DC. Respiratory viruses and exacerbations of asthma in adults. BMJ 1993;307:982-986.
19. Jackson DJ, Johnston SL. The role of viruses in acute exacerbations of asthma. J Allergy Clin Immunol 2010;125:1178-1189.
20. Denlinger LC, Sorkness RL, Lee WM, Evans MD, Wolff MJ, Mathur SK, Crisafi GM, Gaworski KL, Pappas TE, Vrtis RF, et al. Lower airway rhinovirus burden and the seasonal risk of asthma exacerbation. Am J Respir Crit Care Med 2011;184:1007-1014.
21. Denlinger LC, King TS, Cardet JC, Craig TJ, Holguin F, Kraft M, Peters SP, Ross KR, Sumino K, Boushey HA Jr, et al. Vitamin D supplementation and the risk of colds in patients with asthma [abstract 353]. J Allergy Clin Immunol 2015;135:AB109.
22. Nathan RA, Sorkness CA, Kosinski M, Schatz M, Li JT, Marcus P, Murray JJ, Pendergraft TB. Development of the asthma control test: a survey for assessing asthma control. J Allergy Clin Immunol 2004;113:59-65.
23. Barrett B, Brown RL, Mundt MP, Thomas GR, Barlow SK, Highstrom AD, Bahrainian M. Validation of a short form Wisconsin Upper Respiratory Symptom Survey (WURSS-21). Health Qual Life Outcomes 2009;7:76.
24. Walter MJ, Castro M, Kunselman SJ, Chinchilli VM, Reno M, Ramkumar TP, Avila PC, Boushey HA, Ameredes BT, Bleecker ER, et al.; National Heart, Lung and Blood Institute?s Asthma Clinical Research Network. Predicting worsening asthma control following the common cold. Eur Respir J 2008;32:1548-1554.
25. Matsuoka LY, Wortsman J, Haddad JG, Kolm P, Hollis BW. Racial pigmentation and the cutaneous synthesis of vitamin D. Arch Dermatol 1991;127:536-538.
26. Schatz M, Kosinski M, Yarlas AS, Hanlon J, Watson ME, Jhingran P. The minimally important difference of the Asthma Control Test. J Allergy Clin Immunol 2009;124:719-719.e1.
27. Hansdottir S, Monick MM, Hinde SL, Lovan N, Look DC, Hunninghake GW. Respiratory epithelial cells convert inactive vitamin D to its active form: potential effects on host defense. J Immunol 2008;181: 7090-7099.