Sequence type 191 of clonal complex 92 was a dominant carbapenem-resistant Acinetobacter baumannii that causes nosocomial pneumonia in intensive care units in a teaching hospital in central China

Clinical Laboratory

Volumn 62, Issue 8, 2016, Pages 1421-1426

  Tan, Hongyi ^a   Li, Moli ^a,b   Wan, Zhan ^a   Pan, Pinhua ^a   Su, Xiaoli ^a   Hu, Chengpin ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b Chenzhou No 1 People's Hospital   (China)

Author keywords

BlaOXA 23 like gene; BlaOXAU 51 like gene; Carbapenem resistant Acinetobacter baumannii; CC92; ST191

Indexed keywords

CARBAPENEM; IMIPENEM; MEROPENEM;

ACINETOBACTER BAUMANNII; ADULT; AGED; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; BACTERIUM ISOLATE; CHINA; CLINICAL ARTICLE; CLINICAL FEATURE; FEMALE; GENE CLUSTER; GENE SEQUENCE; GENOTYPE; HOSPITAL INFECTION; HUMAN; INTENSIVE CARE UNIT; MALE; MOLECULAR PHYLOGENY; MULTILOCUS SEQUENCE TYPING; MULTIPLEX POLYMERASE CHAIN REACTION; NONHUMAN; PNEUMONIA; TEACHING HOSPITAL;

EID: 84988447199     PISSN: 14336510     EISSN: None     Source Type: Journal    
DOI: 10.7754/Clin.Lab.2016.15114     Document Type: Article

References (22)

1. Luna CM, Aruj PK. Nosocomial Acinetobacter pneumonia. Res-pirology 2007;12(6):787-91.
2. Fagon JY, Chastre J, Hance AJ, Montravers P, Novara A, Gibert C. Nosocomial pneumonia in ventilated patients: a cohort study evaluating attributable mortality and hospital stay. Am J Med 1993;94(3):281-8.
3. Playford EG, Craig JC, Iredell JR. Carbapenem-resistant Acinetobacter baumannii in intensive care unit patients: risk factors for acquisition, infection and their consequences. J Hosp Infect 2007;65(3):204-11.
4. Maragakis LL, Perl TM. Acinetobacter baumannii: epidemiology, antimicrobial resistance, and treatment options. Clin Infect Dis 2008;46(8):1254-63.
5. Kempf M, Rolain JM. Emergence of resistance to carbapenems in Acinetobacter baumannii in Europe: clinical impact and therapeutic options. Int J Antimicrob Agents 2012;39(2):105-14.
6. Fu Y, Zhou J, Zhou H, et al. Wide dissemination of OXA-23-pro-ducing carbapenem-resistant Acinetobacter baumannii clonal complex 22 in multiple cities of China. J Antimicrob Chemother 2010;65(4):644-50.
7. Zhong Q, Xu W, Wu Y, Xu H. Clonal spread of carbapenem non-susceptible Acinetobacter baumannii in an intensive care unit in a teaching hospital in China. Ann Lab Med 2012;32(6):413-9.
8. Liu S, Wang Y, Xu J, et al. Genome sequence of an OXA23-pro-ducing, carbapenem-resistant Acinetobacter baumannii strain of sequence type ST75. J Bacteriol 2012;194(21):6000-1.
9. Huang L, Sun L, Yan Y. Clonal spread of carbapenem resistant Acinetobacter baumannii ST92 in a Chinese Hospital during a 6-year period. J Microbiol 2013;51(1):113-7.
10. OXA-51-like carbapenemase gene intrinsic to this species. J Clin Microbiol 2006;44(8):2974-6.
11. Ruiz M, Marti S, Fernandez-Cuenca F, Pascual A, Vila J. High prevalence of carbapenem-hydrolysing oxacillinases in epidemi-ologically related and unrelated Acinetobacter baumannii clinical isolates in Spain. Clin Microbiol Infect 2007;13(12):1192-8.
12. Islam MA, Talukdar PK, Hoque A, et al. Emergence of multi-drug-resistant NDM-1-producing Gram-negative bacteria in Bangladesh. Eur J Clin Microbiol Infect Dis 2012;31(10):2593-600.
13. Dalla-Costa LM, Coelho JM, Souza HA, et al. Outbreak of carbapenem-resistant Acinetobacter baumannii producing the OXA-23 enzyme in Curitiba, Brazil. J Clin Microbiol 2003;41(7):3403-6.
14. Mansour W, Poirel L, Bettaieb D, Bouallegue O, Boujaafar N, Nordmann P. Dissemination of OXA-23-producing and carbapenem-resistant Acinetobacter baumannii in a University Hospital in Tunisia. Microb Drug Resist 2008;14(4):289-92.
15. Kempf M, Rolain JM, Azza S, et al. Investigation of Acinetobacter baumannii resistance to carbapenems in Marseille hospitals, south of France: a transition from an epidemic to an endemic situation. Apmis 2013;121(1):64-71.
16. He C, Xie Y, Fan H, et al. Spread of imipenem-resistant Acinetobacter baumannii of European clone II in Western China. Int J Antimicrob Agents 2011;38(3):257-60.
17. Dai W, Huang S, Sun S, Cao J, Zhang L. Nosocomial spread of carbapenem-resistant Acinetobacter baumannii (types ST75 and ST137) carrying blaOXA-23-like gene with an upstream ISAbal in a Chinese hospital. Infect Genet Evol 2013;14:98-101.
18. Runnegar N, Sidjabat H, Goh HM, Nimmo GR, Schembri MA, Paterson DL. Molecular epidemiology of multidrug-resistant Acinetobacter baumannii in a single institution over a 10-year period. J Clin Microbiol 2010;48(11):4051-6.
19. Adams-Haduch JM, Onuoha EO, Bogdanovich T, et al. Molecular epidemiology of carbapenem-nonsusceptible Acinetobacter baumannii in the United States. J Clin Microbiol 2011;49(11):3849-54.
20. Rúan Z, Chen Y, Jiang Y, et al. Wide distribution of CC92 carbapenem-resistant and OXA-23-producing Acinetobacter baumannii in multiple provinces of China. Int J Antimicrob Agents 2013;42(4):322-8.
21. Karah N, Haldorsen B, Hermansen NO, et al. Emergence of OXA-carbapenemase- and 16S rRNA methylase-producing international clones of Acinetobacter baumannii in Norway. J Med Microbiol 2011;60(Pt4):515-21.
22. Deng M, Zhu MH, Li JJ, et al. Molecular epidemiology and mechanisms of tigecycline resistance in clinical isolates of Acinetobacter baumannii from a Chinese university hospital. Antimicrob Agents Chemother 2014;58(1):297-303.