Nosocomial spread of carbapenem-resistant Acinetobacter baumannii (types ST75 and ST137) carrying blaOXA-23-like gene with an upstream ISAba1 in a Chinese hospital

Infection, Genetics and Evolution

Volumn 14, Issue 1, 2013, Pages 98-101

  Dai, Wei ^a   Huang, Shifeng ^a   Sun, Shan ^a   Cao, Ju ^a   Zhang, Liping ^a  

^a THE FIRST AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

Acinetobacter baumannii; BlaOXA 23 like Gene; Carbapenem resistance; Carbapenem resistant A. baumannii; ISAba1; Oxacillinases

Indexed keywords

CARBAPENEM; DNA TOPOISOMERASE (ATP HYDROLYSING) B;

ACINETOBACTER BAUMANNII; ACINETOBACTER INFECTION; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIUM IDENTIFICATION; BACTERIUM ISOLATE; BACTERIUM ISOLATION; CHINESE; CONTROLLED STUDY; EPIDEMIC; GENE EXPRESSION; GENETIC SIMILARITY; GENOTYPE; HOSPITAL INFECTION; HUMAN; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR CLONING; MULTILOCUS SEQUENCE TYPING; MULTIPLEX POLYMERASE CHAIN REACTION; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PULSED FIELD GEL ELECTROPHORESIS;

ACINETOBACTER BAUMANNII; ACINETOBACTER INFECTIONS; ALLELES; BETA-LACTAM RESISTANCE; BETA-LACTAMASES; CARBAPENEMS; CHINA; CROSS INFECTION; GENE EXPRESSION; HUMANS; MULTILOCUS SEQUENCE TYPING;

ACINETOBACTER BAUMANNII;

EID: 84871874516     PISSN: 15671348     EISSN: 15677257     Source Type: Journal    
DOI: 10.1016/j.meegid.2012.11.007     Document Type: Article

References (25)

1. Ahmed H., Benjamin A.E., Kevin J.T., Sebastian G.B.A. Characterization of epidemiologically unrelated Acinetobacter baumannii isolates from four continents by use of multilocus sequence typing, pulsed-field gel electrophoresis, and sequence-based typing of blaOXA-51-like genes. J. Clin. Microbiol. 2010, 48:2476-2483.
2. Bartual S.G., Seifert H., Hippler C., Luzon M.A., Wisplinghoff H., Rodríguez-Valera F. Development of a multilocus sequence typing scheme for characterization of clinical isolates of Acinetobacter baumannii. J. Clin. Microbiol. 2005, 43:4382-4390.
3. Bertini A., Poirel L., Mugnier P.D., Villa L., Nordmann P., Carattoli A. Characterization and PCR-based replicon typing of resistance plasmids in Acinetobacter baumannii. Antimicrob. Agents Chemother. 2010, 54:4168-4177.
4. Castanheira M., Jones R.N., Livermore D.M. Antimicrobial activities of doripenem and other carbapenems against Pseudomonas aeruginosa, other nonfermentative bacilli, and Aeromonas spp. Diagn. Microbiol. Infect. Dis. 2009, 63:426-433.
5. Chen T.L., Lee Y.T., Kuo S.C., Hsueh P.R., Chang F.Y., Siu L.K., Ko W.C., Fun C.P. Emergence and distribution of plasmids bearing the blaOXA-51-like gene with an upstream ISAba1 in carbapenem-resistant Acinetobacter baumannii isolates in Taiwan. Antimicrob. Agents Chemother. 2010, 54:4575-4581.
6. Corvec S., Poirel L., Naas T., Drugeon H., Nordmann P. Genetics and expression of the carbapenem-hydrolyzing oxacillinase gene bla OXA-23 in Acinetobacter baumannii. Antimicrob. Agents Chemother. 2007, 51:1530-1533.
7. Esterly J.S., Qi C., Malczynski M., Scheetz M.H. Predictability of doripenem susceptibility in Acinetobacter baumannii isolates based on other carbapenem susceptibilities and bla OXA gene status. Pharmacotherapy 2010, 30:354-360.
8. Figueiredo S., Poirel L., Croize J., Recule C., Nordmann P. In vivo selection of reduced susceptibility to carbapenems in Acinetobacter baumannii related to ISAba1-mediated overexpression of the natural bla (OXA-66) oxacillinase gene. Antimicrob. Agents Chemother. 2009, 53:2657-2659.
9. Fu Y.Q., Zhou J.Y., Zhou H., Yang Q., Wei Z.Q., Yu Y.S., Li L.J. Wide dissemination of OXA-23-producing carbapenem-resistant Acinetobacter baumannii clonal complex 22 in multiple cities of China. J. Antimicrob. Chemother. 2010, 65:644-650.
10. Héritier C., Dubouix A., Poirel L., Marty N., Nordmann P.A. Nosocomial outbreak of Acinetobacter baumannii isolates expressing the carbapenem-hydrolysing oxacillinase OXA-58. J. Antimicrob. Chemother. 2005, 55:115-118.
11. Heritier C., Poirel L., Lambert T., Nordmann P. Contribution of acquired carbapenem-hydrolyzing oxacillinases to carbapenem resistance in Acinetobacter baumannii. Antimicrob. Agents Chemother. 2005, 49:3198-3202.
12. Higgins P.G., Poirel L., Lehmann M., Nordmann P., Seifert H. OXA-143, a novel carbapenem-hydrolyzing class D β-Lactamase in Acinetobacter baumannii. Antimicrob. Agents Chemother. 2009, 53:5035-5038.
13. Kim Y.J., Kim S.I., Kim Y.R., Hong K.W., Wie S.H., Park Y.J., Jeong H., Kang M.W. Carbapenem-resistant Acinetobacter baumannii: diversity of resistant mechanisms and risk factors for infection. Epidemiol. Infect. 2011, 18:1-9.
14. Michalopoulos A., Falagas M.E. Treatment of Acinetobacter infections. Expert Opin. Pharmacother. 2010, 11:779-788.
15. Peleg A.Y., Seifert H., Paterson D.L. Acinetobacter baumannii: emergence of a successful pathogen. Clin. Microbiol. Rev. 2008, 21:538-582.
16. Poirel L., Nordmann P. Carbapenem resistance in Acinetobacter baumannii: mechanisms and epidemiology. Clin. Microbiol. Infect. 2006, 12:826-836.
17. Poirel L., Nordmann P. Genetic structures at the origin of acquisition and expression of the carbapenem-hydrolyzing oxacillinase gene bla OXA-58 in Acinetobacter baumannii. Antimicrob. Agents Chemother. 2006, 50:1442-1448.
18. Stoeva T., Higgins P.G., Savov E., Markovska R., Mitov I., Seifert H. Nosocomial spread of OXA-23 and OXA-58 β-lactamase-producing Acinetobacter baumannii in a Bulgarian hospital. J. Antimicrob. Chemother. 2009, 63:618-620.
19. Tenover F.C., Arbeit R.D., Goering R.V., Mickelsen P.A., Murray B.E., Persing D.H., Swaminathan B. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J. Clin. Microbiol. 1995, 33:2233-2239.
20. Turton J.F., Gabriel S.N., Valderrey C., Kaufmann M.E., Pitt T.L. Use of sequence-based typing and multiplex PCR to identify clonal lineages of outbreak strains of Acinetobacter baumannii. Clin. Microbiol. Infect. 2007, 13:807-815.
21. Turton J.F., Ward M.E., Woodford N., Kaufmann M.E., Pike R., Livermore D.M., Pitt T.L. The role of ISAba1 in expression of OXA carbapenemase genes in Acinetobacter baumannii. FEMS Microbiol. Lett. 2006, 258:72-77.
22. Wang X., Zong Z., Lu X. Tn2008 is a major vehicle carrying bla(OXA-23) in Acinetobacter baumannii from China. Diagn. Microbiol. Infect. Dis. 2011, 69:218-222.
23. Woodford N., Ellington M.J., Coelho J.M., Turton J.F., Ward M.E., Brown S., Amyes S.G., Livermore D.M. Multiplex PCR for genes encoding prevalent OXA carbapenemases in Acinetobacter spp. Int. J. Antimicrob. Agents 2006, 27:351-353.
24. Zhou H., Pi B.R., Yang Q., Yu Y.S., Chen Y.G., Li L.J., Zheng S.S. Dissemination of imipenem-resistant Acinetobacter baumannii strains carrying the ISAba1 bla OXA-23 genes in a Chinese hospital. J. Med. Microbiol. 2007, 56:1076-1080.
25. Zhou H., Zhang T.W., Yu D.L., Pi B.R., Yang Q., Zhou J.Y., Hu S.N., Yu Y.S. Genomic analysis of the multidrug-resistant Acinetobacter baumannii Strain MDR-ZJ06 widely spread in China. Antimicrob. Agents Chemother. 2011, 55:4506-4512.