Efficacy and safety of hepcidin-based screen-and-treat approaches using two different doses versus a standard universal approach of iron supplementation in young children in rural Gambia: A double-blind randomised controlled trial

BMC Pediatrics

Volumn 16, Issue 1, 2016, Pages

  Wegmüller, Rita ^a   Bah, Amat ^a   Kendall, Lindsay ^b   Goheen, Morgan M ^c   Mulwa, Sarah ^b   Cerami, Carla ^d   Moretti, Diego ^e   Prentice, Andrew M ^a  

^a MRC International Nutrition Group   (Gambia)

^b Disease Control and Elimination   (Gambia)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d University of North Carolina at Chapel Hill   (United States)

^e ETH ZURICH   (Switzerland)

Author keywords

Anaemia; Children; Gambia; Hepcidin; Iron deficiency; Iron deficiency anaemia; Iron supplementation; Safety; Sub Saharan Africa

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; COBALAMIN; COPPER; FOLIC ACID; HEMOGLOBIN; HEPCIDIN; IODINE; IRON; NICOTINIC ACID; PYRIDOXINE; RETINOL; RIBOFLAVIN; SELENIUM; THIAMINE; TRANSFERRIN; TRANSFERRIN RECEPTOR; VITAMIN D; ZINC; BIOLOGICAL MARKER; FERROUS FUMARATE; FERROUS ION; TRACE ELEMENT;

AGE; ARTICLE; BACTERIAL GROWTH; BODY HEIGHT; BODY WEIGHT; CAREGIVER; CHILD CARE; CONTROLLED STUDY; DIET SUPPLEMENTATION; DOUBLE BLIND PROCEDURE; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG SAFETY; GAMBIA; HEMOGLOBIN BLOOD LEVEL; HUMAN; IN VITRO STUDY; INFANT; INFECTION; INTESTINE FLORA; IRON DEFICIENCY; MAJOR CLINICAL STUDY; MALARIA; PARALLEL DESIGN; PLASMODIUM FALCIPARUM; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; RURAL AREA; SCREENING TEST; TREATMENT DURATION; TREATMENT OUTCOME; ANEMIA, IRON-DEFICIENCY; BLOOD; CLINICAL PROTOCOL; COMPARATIVE STUDY; DEVELOPING COUNTRY; DIETARY SUPPLEMENT; FEMALE; FOLLOW UP; MALE; MASS SCREENING; METABOLISM; PROCEDURES; RURAL HEALTH; RURAL HEALTH CARE;

ANEMIA, IRON-DEFICIENCY; BIOMARKERS; CLINICAL PROTOCOLS; DEVELOPING COUNTRIES; DIETARY SUPPLEMENTS; DOUBLE-BLIND METHOD; FEMALE; FERROUS COMPOUNDS; FOLLOW-UP STUDIES; GAMBIA; HEMOGLOBINS; HEPCIDINS; HUMANS; INFANT; MALE; MASS SCREENING; MICRONUTRIENTS; PROSPECTIVE STUDIES; RURAL HEALTH; RURAL HEALTH SERVICES;

EID: 84987740837     PISSN: None     EISSN: 14712431     Source Type: Journal    
DOI: 10.1186/s12887-016-0689-4     Document Type: Article

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