메뉴 건너뛰기




Volumn 462, Issue , 2016, Pages 90-95

Interleukin 35: A novel candidate biomarker to diagnose early onset sepsis in neonates

Author keywords

Biomarker; Early onset sepsis; Interleukin 35; Neonate

Indexed keywords

C REACTIVE PROTEIN; INTERLEUKIN 35; PROCALCITONIN; BIOLOGICAL MARKER; INTERLEUKIN DERIVATIVE; INTERLEUKIN-35, HUMAN;

EID: 84986880381     PISSN: 00098981     EISSN: 18733492     Source Type: Journal    
DOI: 10.1016/j.cca.2016.09.005     Document Type: Article
Times cited : (21)

References (48)
  • 1
    • 84941178180 scopus 로고    scopus 로고
    • Global, regional, and national causes of child mortality in 2000–13, with projections to inform post-2015 priorities: an updated systematic analysis
    • [1] Liu, L., Oza, S., Hogan, D., Perin, J., Rudan, I., Lawn, J.E., et al. Global, regional, and national causes of child mortality in 2000–13, with projections to inform post-2015 priorities: an updated systematic analysis. Lancet 385:9966 (2015), 430–440.
    • (2015) Lancet , vol.385 , Issue.9966 , pp. 430-440
    • Liu, L.1    Oza, S.2    Hogan, D.3    Perin, J.4    Rudan, I.5    Lawn, J.E.6
  • 2
    • 84861926839 scopus 로고    scopus 로고
    • Global, regional, and national causes of child mortality: an updated systematic analysis for 2010 with time trends since 2000
    • [2] Liu, L., Johnson, H.L., Cousens, S., Perin, J., Scott, S., Lawn, J.E., et al. Global, regional, and national causes of child mortality: an updated systematic analysis for 2010 with time trends since 2000. Lancet 379:9832 (2012), 2151–2161.
    • (2012) Lancet , vol.379 , Issue.9832 , pp. 2151-2161
    • Liu, L.1    Johnson, H.L.2    Cousens, S.3    Perin, J.4    Scott, S.5    Lawn, J.E.6
  • 3
    • 84860587209 scopus 로고    scopus 로고
    • Management of neonates with suspected or proven early-onset bacterial sepsis
    • [3] Polin, R.A., F. Committee on, Newborn, Management of neonates with suspected or proven early-onset bacterial sepsis. Pediatrics 129:5 (2012), 1006–1015.
    • (2012) Pediatrics , vol.129 , Issue.5 , pp. 1006-1015
    • Polin, R.A.1    F. Committee on, Newborn,2
  • 6
    • 84891796205 scopus 로고    scopus 로고
    • Stratification of risk of early-onset sepsis in newborns >/= 34 weeks' gestation
    • [6] Escobar, G.J., Puopolo, K.M., Wi, S., Turk, B.J., Kuzniewicz, M.W., Walsh, E.M., et al. Stratification of risk of early-onset sepsis in newborns >/= 34 weeks' gestation. Pediatrics 133:1 (2014), 30–36.
    • (2014) Pediatrics , vol.133 , Issue.1 , pp. 30-36
    • Escobar, G.J.1    Puopolo, K.M.2    Wi, S.3    Turk, B.J.4    Kuzniewicz, M.W.5    Walsh, E.M.6
  • 7
    • 77956628404 scopus 로고    scopus 로고
    • Sepsis biomarkers: a review
    • [7] Pierrakos, C., Vincent, J.-L., Sepsis biomarkers: a review. Crit. Care, 14(1), 2010, R15.
    • (2010) Crit. Care , vol.14 , Issue.1 , pp. R15
    • Pierrakos, C.1    Vincent, J.-L.2
  • 8
    • 33644846534 scopus 로고    scopus 로고
    • Empiric use of ampicillin and cefotaxime, compared with ampicillin and gentamicin, for neonates at risk for sepsis is associated with an increased risk of neonatal death
    • [8] Clark, R.H., Bloom, B.T., Spitzer, A.R., Gerstmann, D.R., Empiric use of ampicillin and cefotaxime, compared with ampicillin and gentamicin, for neonates at risk for sepsis is associated with an increased risk of neonatal death. Pediatrics 117:1 (2006), 67–74.
    • (2006) Pediatrics , vol.117 , Issue.1 , pp. 67-74
    • Clark, R.H.1    Bloom, B.T.2    Spitzer, A.R.3    Gerstmann, D.R.4
  • 9
    • 33748427541 scopus 로고    scopus 로고
    • The association of third-generation cephalosporin use and invasive candidiasis in extremely low birth-weight infants
    • [9] Cotten, C.M., McDonald, S., Stoll, B., Goldberg, R.N., Poole, K., Benjamin, D.K. Jr., et al. The association of third-generation cephalosporin use and invasive candidiasis in extremely low birth-weight infants. Pediatrics 118:2 (2006), 717–722.
    • (2006) Pediatrics , vol.118 , Issue.2 , pp. 717-722
    • Cotten, C.M.1    McDonald, S.2    Stoll, B.3    Goldberg, R.N.4    Poole, K.5    Benjamin, D.K.6
  • 10
    • 63749083957 scopus 로고    scopus 로고
    • Is thrombocytopenia suggestive of organism-specific response in neonatal sepsis?
    • [10] Manzoni, P., Mostert, M., Galletto, P., Gastaldo, L., Gallo, E., Agriesti, G., et al. Is thrombocytopenia suggestive of organism-specific response in neonatal sepsis?. Pediatr. Int. 51:2 (2009), 206–210.
    • (2009) Pediatr. Int. , vol.51 , Issue.2 , pp. 206-210
    • Manzoni, P.1    Mostert, M.2    Galletto, P.3    Gastaldo, L.4    Gallo, E.5    Agriesti, G.6
  • 11
    • 41849145315 scopus 로고    scopus 로고
    • Expected ranges for blood neutrophil concentrations of neonates: the Manroe and Mouzinho charts revisited
    • [11] Schmutz, N., Henry, E., Jopling, J., Christensen, R.D., Expected ranges for blood neutrophil concentrations of neonates: the Manroe and Mouzinho charts revisited. J. Perinatol. 28:4 (2008), 275–281.
    • (2008) J. Perinatol. , vol.28 , Issue.4 , pp. 275-281
    • Schmutz, N.1    Henry, E.2    Jopling, J.3    Christensen, R.D.4
  • 12
    • 0032185465 scopus 로고    scopus 로고
    • Serial serum C-reactive protein levels in the diagnosis of neonatal infection
    • [12] Benitz, W.E., Han, M.Y., Madan, A., Ramachandra, P., Serial serum C-reactive protein levels in the diagnosis of neonatal infection. Pediatrics, 102(4), 1998, E41.
    • (1998) Pediatrics , vol.102 , Issue.4
    • Benitz, W.E.1    Han, M.Y.2    Madan, A.3    Ramachandra, P.4
  • 13
    • 84880302096 scopus 로고    scopus 로고
    • Comparative assessment of cytokines and other inflammatory markers for the early diagnosis of neonatal sepsis-a case control study
    • [13] Prashant, A., Vishwanath, P., Kulkarni, P., Sathya Narayana, P., Gowdara, V., Nataraj, S.M., et al. Comparative assessment of cytokines and other inflammatory markers for the early diagnosis of neonatal sepsis-a case control study. PLoS One, 8(7), 2013, e68426.
    • (2013) PLoS One , vol.8 , Issue.7
    • Prashant, A.1    Vishwanath, P.2    Kulkarni, P.3    Sathya Narayana, P.4    Gowdara, V.5    Nataraj, S.M.6
  • 14
    • 36549030784 scopus 로고    scopus 로고
    • The inhibitory cytokine IL-35 contributes to regulatory T-cell function
    • [14] Collison, L.W., Workman, C.J., Kuo, T.T., Boyd, K., Wang, Y., Vignali, K.M., et al. The inhibitory cytokine IL-35 contributes to regulatory T-cell function. Nature 450:7169 (2007), 566–569.
    • (2007) Nature , vol.450 , Issue.7169 , pp. 566-569
    • Collison, L.W.1    Workman, C.J.2    Kuo, T.T.3    Boyd, K.4    Wang, Y.5    Vignali, K.M.6
  • 15
    • 84455199735 scopus 로고    scopus 로고
    • IL-35 production by inducible costimulator (ICOS)-positive regulatory T cells reverses established IL-17-dependent allergic airways disease
    • [15] Whitehead, G.S., Wilson, R.H., Nakano, K., Burch, L.H., Nakano, H., Cook, D.N., IL-35 production by inducible costimulator (ICOS)-positive regulatory T cells reverses established IL-17-dependent allergic airways disease. J. Allergy Clin. Immunol. 129:1 (2012), 207–215, e201–205.
    • (2012) J. Allergy Clin. Immunol. , vol.129 , Issue.1 , pp. 207-215
    • Whitehead, G.S.1    Wilson, R.H.2    Nakano, K.3    Burch, L.H.4    Nakano, H.5    Cook, D.N.6
  • 16
    • 79960434330 scopus 로고    scopus 로고
    • Airway inflammation and IgE production induced by dust mite allergen-specific memory/effector Th2 cell line can be effectively attenuated by IL-35
    • [16] Huang, C.H., Loo, E.X., Kuo, I.C., Soh, G.H., Goh, D.L., Lee, B.W., et al. Airway inflammation and IgE production induced by dust mite allergen-specific memory/effector Th2 cell line can be effectively attenuated by IL-35. J. Immunol. 187:1 (2011), 462–471.
    • (2011) J. Immunol. , vol.187 , Issue.1 , pp. 462-471
    • Huang, C.H.1    Loo, E.X.2    Kuo, I.C.3    Soh, G.H.4    Goh, D.L.5    Lee, B.W.6
  • 17
    • 84941942616 scopus 로고    scopus 로고
    • Interleukin 35: critical regulator of immunity and lymphocyte-mediated diseases
    • [17] Egwuagu, C.E., Yu, C.R., Sun, L., Wang, R., Interleukin 35: critical regulator of immunity and lymphocyte-mediated diseases. Cytokine Growth Factor Rev. 26:5 (2015), 587–593.
    • (2015) Cytokine Growth Factor Rev. , vol.26 , Issue.5 , pp. 587-593
    • Egwuagu, C.E.1    Yu, C.R.2    Sun, L.3    Wang, R.4
  • 18
    • 84942512208 scopus 로고    scopus 로고
    • IL-35 is elevated in clinical and experimental sepsis and mediates inflammation
    • [18] Cao, J., Xu, F., Lin, S., Tao, X., Xiang, Y., Lai, X., et al. IL-35 is elevated in clinical and experimental sepsis and mediates inflammation. Clin. Immunol. 161:2 (2015), 89–95.
    • (2015) Clin. Immunol. , vol.161 , Issue.2 , pp. 89-95
    • Cao, J.1    Xu, F.2    Lin, S.3    Tao, X.4    Xiang, Y.5    Lai, X.6
  • 20
    • 79955567272 scopus 로고    scopus 로고
    • Serum procalcitonin as a diagnostic marker for neonatal sepsis: a systematic review and meta-analysis
    • [20] Vouloumanou, E.K., Plessa, E., Karageorgopoulos, D.E., Mantadakis, E., Falagas, M.E., Serum procalcitonin as a diagnostic marker for neonatal sepsis: a systematic review and meta-analysis. Intensive Care Med. 37:5 (2011), 747–762.
    • (2011) Intensive Care Med. , vol.37 , Issue.5 , pp. 747-762
    • Vouloumanou, E.K.1    Plessa, E.2    Karageorgopoulos, D.E.3    Mantadakis, E.4    Falagas, M.E.5
  • 21
    • 77956855060 scopus 로고    scopus 로고
    • The accuracy of the procalcitonin test for the diagnosis of neonatal sepsis: a meta-analysis
    • [21] Yu, Z., Liu, J., Sun, Q., Qiu, Y., Han, S., Guo, X., The accuracy of the procalcitonin test for the diagnosis of neonatal sepsis: a meta-analysis. Scand. J. Infect. Dis. 42:10 (2010), 723–733.
    • (2010) Scand. J. Infect. Dis. , vol.42 , Issue.10 , pp. 723-733
    • Yu, Z.1    Liu, J.2    Sun, Q.3    Qiu, Y.4    Han, S.5    Guo, X.6
  • 22
    • 84925762421 scopus 로고    scopus 로고
    • Diagnosis and evaluation of severity of sepsis via the use of biomarkers and profiles of 13 cytokines: a multiplex analysis
    • [22] Jekarl, D.W., Kim, J.Y., Lee, S., Kim, M., Kim, Y., Han, K., et al. Diagnosis and evaluation of severity of sepsis via the use of biomarkers and profiles of 13 cytokines: a multiplex analysis. Clin. Chem. Lab. Med. 53:4 (2015), 575–581.
    • (2015) Clin. Chem. Lab. Med. , vol.53 , Issue.4 , pp. 575-581
    • Jekarl, D.W.1    Kim, J.Y.2    Lee, S.3    Kim, M.4    Kim, Y.5    Han, K.6
  • 23
    • 70349262651 scopus 로고    scopus 로고
    • Use of procalcitonin-guided decision-making to shorten antibiotic therapy in suspected neonatal early-onset sepsis: prospective randomized intervention trial
    • [23] Stocker, M., Fontana, M., El Helou, S., Wegscheider, K., Berger, T.M., Use of procalcitonin-guided decision-making to shorten antibiotic therapy in suspected neonatal early-onset sepsis: prospective randomized intervention trial. Neonatology 97:2 (2010), 165–174.
    • (2010) Neonatology , vol.97 , Issue.2 , pp. 165-174
    • Stocker, M.1    Fontana, M.2    El Helou, S.3    Wegscheider, K.4    Berger, T.M.5
  • 24
    • 74049160280 scopus 로고    scopus 로고
    • Antibiotic use in neonatal intensive care units and adherence with Centers for Disease Control and Prevention 12 Step Campaign to Prevent Antimicrobial Resistance
    • [24] Patel, S.J., Oshodi, A., Prasad, P., Delamora, P., Larson, E., Zaoutis, T., et al. Antibiotic use in neonatal intensive care units and adherence with Centers for Disease Control and Prevention 12 Step Campaign to Prevent Antimicrobial Resistance. Pediatr. Infect. Dis. J. 28:12 (2009), 1047–1051.
    • (2009) Pediatr. Infect. Dis. J. , vol.28 , Issue.12 , pp. 1047-1051
    • Patel, S.J.1    Oshodi, A.2    Prasad, P.3    Delamora, P.4    Larson, E.5    Zaoutis, T.6
  • 25
    • 84874215662 scopus 로고    scopus 로고
    • Impact of formulary restriction with prior authorization by an antimicrobial stewardship program
    • [25] Reed, E.E., Stevenson, K.B., West, J.E., Bauer, K.A., Goff, D.A., Impact of formulary restriction with prior authorization by an antimicrobial stewardship program. Virulence 4:2 (2013), 158–162.
    • (2013) Virulence , vol.4 , Issue.2 , pp. 158-162
    • Reed, E.E.1    Stevenson, K.B.2    West, J.E.3    Bauer, K.A.4    Goff, D.A.5
  • 26
    • 33847049441 scopus 로고    scopus 로고
    • Antibiotic-resistant organisms in the neonatal intensive care unit
    • [26] Bizzarro, M.J., Gallagher, P.G., Antibiotic-resistant organisms in the neonatal intensive care unit. Semin. Perinatol. 31:1 (2007), 26–32.
    • (2007) Semin. Perinatol. , vol.31 , Issue.1 , pp. 26-32
    • Bizzarro, M.J.1    Gallagher, P.G.2
  • 27
    • 59449084598 scopus 로고    scopus 로고
    • Prolonged duration of initial empirical antibiotic treatment is associated with increased rates of necrotizing enterocolitis and death for extremely low birth weight infants
    • [27] Cotten, C.M., Taylor, S., Stoll, B., Goldberg, R.N., Hansen, N.I., Sanchez, P.J., et al. Prolonged duration of initial empirical antibiotic treatment is associated with increased rates of necrotizing enterocolitis and death for extremely low birth weight infants. Pediatrics 123:1 (2009), 58–66.
    • (2009) Pediatrics , vol.123 , Issue.1 , pp. 58-66
    • Cotten, C.M.1    Taylor, S.2    Stoll, B.3    Goldberg, R.N.4    Hansen, N.I.5    Sanchez, P.J.6
  • 28
    • 79953019017 scopus 로고    scopus 로고
    • Time to positivity of neonatal blood cultures: fast and furious?
    • [28] Guerti, K., Devos, H., Ieven, M.M., Mahieu, L.M., Time to positivity of neonatal blood cultures: fast and furious?. J. Med. Microbiol. 60:Pt 4 (2011), 446–453.
    • (2011) J. Med. Microbiol. , vol.60 , pp. 446-453
    • Guerti, K.1    Devos, H.2    Ieven, M.M.3    Mahieu, L.M.4
  • 29
    • 77953533229 scopus 로고    scopus 로고
    • International perspective on early-onset neonatal sepsis
    • [29] Ganatra, H.A., Stoll, B.J., Zaidi, A.K., International perspective on early-onset neonatal sepsis. Clin. Perinatol. 37:2 (2010), 501–523.
    • (2010) Clin. Perinatol. , vol.37 , Issue.2 , pp. 501-523
    • Ganatra, H.A.1    Stoll, B.J.2    Zaidi, A.K.3
  • 30
    • 0030700003 scopus 로고    scopus 로고
    • Epstein–Barr virus-induced gene 3 and the p35 subunit of interleukin 12 form a novel heterodimeric hematopoietin
    • [30] Devergne, O., Birkenbach, M., Kieff, E., Epstein–Barr virus-induced gene 3 and the p35 subunit of interleukin 12 form a novel heterodimeric hematopoietin. Proc. Natl. Acad. Sci. U. S. A. 94:22 (1997), 12041–12046.
    • (1997) Proc. Natl. Acad. Sci. U. S. A. , vol.94 , Issue.22 , pp. 12041-12046
    • Devergne, O.1    Birkenbach, M.2    Kieff, E.3
  • 31
    • 55149104594 scopus 로고    scopus 로고
    • Interleukin-35: odd one out or part of the family?
    • [31] Collison, L.W., Vignali, D.A., Interleukin-35: odd one out or part of the family?. Immunol. Rev. 226:1 (2008), 248–262.
    • (2008) Immunol. Rev. , vol.226 , Issue.1 , pp. 248-262
    • Collison, L.W.1    Vignali, D.A.2
  • 32
    • 84895534422 scopus 로고    scopus 로고
    • Interleukin 35: a key mediator of suppression and the propagation of infectious tolerance
    • [32] Olson, B.M., Sullivan, J.A., Burlingham, W.J., Interleukin 35: a key mediator of suppression and the propagation of infectious tolerance. Front. Immunol., 4, 2013, 315.
    • (2013) Front. Immunol. , vol.4 , pp. 315
    • Olson, B.M.1    Sullivan, J.A.2    Burlingham, W.J.3
  • 33
    • 84878586670 scopus 로고    scopus 로고
    • Human placental trophoblasts express the immunosuppressive cytokine IL-35
    • [33] Mao, H., Gao, W., Ma, C., Sun, J., Liu, J., Shao, Q., et al. Human placental trophoblasts express the immunosuppressive cytokine IL-35. Hum. Immunol. 74:7 (2013), 872–877.
    • (2013) Hum. Immunol. , vol.74 , Issue.7 , pp. 872-877
    • Mao, H.1    Gao, W.2    Ma, C.3    Sun, J.4    Liu, J.5    Shao, Q.6
  • 35
    • 80054856034 scopus 로고    scopus 로고
    • Interleukin-35 mediates mucosal immune responses that protect against t-cell–dependent colitis
    • [35] Wirtz, S., Billmeier, U., Mchedlidze, T., Blumberg, R.S., Neurath, M.F., Interleukin-35 mediates mucosal immune responses that protect against t-cell–dependent colitis. Gastroenterology 141:5 (2011), 1875–1886.
    • (2011) Gastroenterology , vol.141 , Issue.5 , pp. 1875-1886
    • Wirtz, S.1    Billmeier, U.2    Mchedlidze, T.3    Blumberg, R.S.4    Neurath, M.F.5
  • 36
    • 84862297381 scopus 로고    scopus 로고
    • Erythromycin enhances CD4 + Foxp3 + regulatory T-cell responses in a rat model of smoke-induced lung inflammation
    • [36] Bai, J., Qiu, S.L., Zhong, X.N., Huang, Q.P., He, Z.Y., Zhang, J.Q., et al. Erythromycin enhances CD4 + Foxp3 + regulatory T-cell responses in a rat model of smoke-induced lung inflammation. Mediat. Inflamm., 2012, 2012, 410232.
    • (2012) Mediat. Inflamm. , vol.2012 , pp. 410232
    • Bai, J.1    Qiu, S.L.2    Zhong, X.N.3    Huang, Q.P.4    He, Z.Y.5    Zhang, J.Q.6
  • 37
    • 84874256945 scopus 로고    scopus 로고
    • Immunosuppression in sepsis: a novel understanding of the disorder and a new therapeutic approach
    • [37] Hotchkiss, R.S., Monneret, G., Payen, D., Immunosuppression in sepsis: a novel understanding of the disorder and a new therapeutic approach. Lancet Infect. Dis. 13:3 (2013), 260–268.
    • (2013) Lancet Infect. Dis. , vol.13 , Issue.3 , pp. 260-268
    • Hotchkiss, R.S.1    Monneret, G.2    Payen, D.3
  • 38
    • 84956708941 scopus 로고    scopus 로고
    • Interleukin-35 is upregulated in response to influenza virus infection and secondary bacterial pneumonia
    • [38] Chen, Y., Wang, C.J., Lin, S.H., Zhang, M., Li, S.Y., Xu, F., Interleukin-35 is upregulated in response to influenza virus infection and secondary bacterial pneumonia. Cytokine 81 (2016), 23–27.
    • (2016) Cytokine , vol.81 , pp. 23-27
    • Chen, Y.1    Wang, C.J.2    Lin, S.H.3    Zhang, M.4    Li, S.Y.5    Xu, F.6
  • 39
    • 84881633242 scopus 로고    scopus 로고
    • Enhanced acute immune response in IL-12p35 −/− mice is followed by accelerated distinct repair mechanisms in Staphylococcus aureus–induced murine brain abscess
    • [39] Held, J., Preuße, C., Döser, A., Richter, L., Heppner, F.L., Stenzel, W., Enhanced acute immune response in IL-12p35 −/− mice is followed by accelerated distinct repair mechanisms in Staphylococcus aureus–induced murine brain abscess. J. Infect. Dis. 208:5 (2013), 749–760.
    • (2013) J. Infect. Dis. , vol.208 , Issue.5 , pp. 749-760
    • Held, J.1    Preuße, C.2    Döser, A.3    Richter, L.4    Heppner, F.L.5    Stenzel, W.6
  • 40
    • 33746931178 scopus 로고    scopus 로고
    • Protection from lethal septic peritonitis by neutralizing the biological function of interleukin 27
    • [40] Wirtz, S., Tubbe, I., Galle, P.R., Schild, H.J., Birkenbach, M., Blumberg, R.S., et al. Protection from lethal septic peritonitis by neutralizing the biological function of interleukin 27. J. Exp. Med. 203:8 (2006), 1875–1881.
    • (2006) J. Exp. Med. , vol.203 , Issue.8 , pp. 1875-1881
    • Wirtz, S.1    Tubbe, I.2    Galle, P.R.3    Schild, H.J.4    Birkenbach, M.5    Blumberg, R.S.6
  • 42
    • 33748878798 scopus 로고    scopus 로고
    • Values of C-reactive protein, procalcitonin, and Staphylococcus-specific PCR in neonatal late-onset sepsis
    • [42] Makhoul, I.R., Yacoub, A., Smolkin, T., Sujov, P., Kassis, I., Sprecher, H., Values of C-reactive protein, procalcitonin, and Staphylococcus-specific PCR in neonatal late-onset sepsis. Acta Paediatr. 95:10 (2006), 1218–1223.
    • (2006) Acta Paediatr. , vol.95 , Issue.10 , pp. 1218-1223
    • Makhoul, I.R.1    Yacoub, A.2    Smolkin, T.3    Sujov, P.4    Kassis, I.5    Sprecher, H.6
  • 43
    • 79955002998 scopus 로고    scopus 로고
    • C reactive protein and procalcitonin: reference intervals for preterm and term newborns during the early neonatal period
    • [43] Chiesa, C., Natale, F., Pascone, R., Osborn, J.F., Pacifico, L., Bonci, E., et al. C reactive protein and procalcitonin: reference intervals for preterm and term newborns during the early neonatal period. Clin. Chim. Acta 412:11 − 12 (2011), 1053–1059.
    • (2011) Clin. Chim. Acta , vol.412 , Issue.11-12 , pp. 1053-1059
    • Chiesa, C.1    Natale, F.2    Pascone, R.3    Osborn, J.F.4    Pacifico, L.5    Bonci, E.6
  • 44
    • 84955255287 scopus 로고    scopus 로고
    • Neutrophil CD64 combined with PCT, CRP and WBC improves the sensitivity for the early diagnosis of neonatal sepsis
    • [44] Yang, A.P., Liu, J., Yue, L.H., Wang, H.Q., Yang, W.J., Yang, G.H., Neutrophil CD64 combined with PCT, CRP and WBC improves the sensitivity for the early diagnosis of neonatal sepsis. Clin. Chem. Lab. Med. 54:2 (2016), 345–351.
    • (2016) Clin. Chem. Lab. Med. , vol.54 , Issue.2 , pp. 345-351
    • Yang, A.P.1    Liu, J.2    Yue, L.H.3    Wang, H.Q.4    Yang, W.J.5    Yang, G.H.6
  • 45
    • 0037230480 scopus 로고    scopus 로고
    • C-reactive protein, interleukin-6, and procalcitonin in the immediate postnatal period: influence of illness severity, risk status, antenatal and perinatal complications, and infection
    • [45] Chiesa, C., Pellegrini, G., Panero, A., Osborn, J.F., Signore, F., Assumma, M., et al. C-reactive protein, interleukin-6, and procalcitonin in the immediate postnatal period: influence of illness severity, risk status, antenatal and perinatal complications, and infection. Clin. Chem. 49:1 (2003), 60–68.
    • (2003) Clin. Chem. , vol.49 , Issue.1 , pp. 60-68
    • Chiesa, C.1    Pellegrini, G.2    Panero, A.3    Osborn, J.F.4    Signore, F.5    Assumma, M.6
  • 48
    • 84959273475 scopus 로고    scopus 로고
    • The third international consensus definitions for sepsis and septic shock (sepsis-3)
    • [48] Singer, M., Deutschman, C.S., Seymour, C.W., Shankar-Hari, M., Annane, D., Bauer, M., et al. The third international consensus definitions for sepsis and septic shock (sepsis-3). JAMA 315:8 (2016), 801–810.
    • (2016) JAMA , vol.315 , Issue.8 , pp. 801-810
    • Singer, M.1    Deutschman, C.S.2    Seymour, C.W.3    Shankar-Hari, M.4    Annane, D.5    Bauer, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.