Comparative Assessment of Cytokines and Other Inflammatory Markers for the Early Diagnosis of Neonatal Sepsis-A Case Control Study

PLoS ONE

Volumn 8, Issue 7, 2013, Pages

  Prashant, Akila ^a   Vishwanath, Prashant ^a   Kulkarni, Praveen ^a   Sathya Narayana, Prashanth ^a   Gowdara, Vijaykumar ^a   Nataraj, Suma M ^a   Nagaraj, Rashmi ^a  

^a JSS MEDICAL COLLEGE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; C REACTIVE PROTEIN; CD163 ANTIGEN; INTERLEUKIN 6; INTERLEUKIN 8; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BLOOD SAMPLING; CASE CONTROL STUDY; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE COURSE; EARLY DIAGNOSIS; FEMALE; HUMAN; INFLAMMATION; MALE; NEWBORN; NEWBORN SEPSIS; PROTEIN BLOOD LEVEL; SENSITIVITY AND SPECIFICITY; TREATMENT RESPONSE; UMBILICAL CORD BLOOD;

ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; CASE-CONTROL STUDIES; EARLY DIAGNOSIS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; INFANT, NEWBORN; INTERLEUKIN-6; INTERLEUKIN-8; MALE; RECEPTORS, CELL SURFACE; SENSITIVITY AND SPECIFICITY; SEPSIS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84880302096     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0068426     Document Type: Article

References (26)

1. Dollner H, Vatten L, Austgulen R, (2001) Early diagnostic markers for neonatal sepsis: Comparing C-reactive protein, interleukin-6, soluble tumour necrosis factor receptors and soluble adhesion molecules. Journal of clinical epidemiology 54: 1251-1257.
2. Sastre JBL, Solis DP, Serradilla VR, Colomer BF, Cotallo GDC, et al. (2006) Procalcitonin is not sufficiently reliable to be the sole marker of neonatal sepsis of nosocomial origin. BMC Pediatrics 6: 16.
3. Ng PC, Li K, Chui KM, Leung TF, Wong RPO, et al. (2007) IP-10 is an early diagnostic marker for identification of late-onset bacterial infection in preterm infants. Pediatric Research 61: 93-98.
4. Ng PC, Lam HS, (2006) Diagnostic markers for neonatal sepsis. Curr Opin Pediatr 18: 125-131.
5. Ng PC, Cheng SH, Chui KM, Fok TF, Wong MY, et al. (1997) Diagnosis of late onset neonatal sepsis with cytokines, adhesion molecule, and C-reactive protein in preterm very low birth weight infants. Arch Dis Child Fetal Neonatal Ed 77: F221-7.
6. Davis BH, Zarev PV, (2005) Human monocyte CD163 expression inversely correlates with soluble CD163 plasma levels. Cytometry part B (clinical cytometry) 63B: 16-22.
7. Clinical and Laboratory Standards Institute (CLSI) (formerly NCCLS) (2007) Principles and procedures for blood cultures; Approved guidelines. CLSI document M47-A (ISBN 1-56238-641-7) Vol. 27 No.17.
8. Qazi SA, Stoll BJ, (2009) Neonatal sepsis: A major global public health challenge. Pediatr Infect Dis J 28: S1-2.
9. National Collaborating Centre for Women's and Children's Health, Commissioned by the National Institute for Health and Clinical Excellence (2007) Feverish illness in children: assessment and initial management in children younger than 5 years. London: RCOG Press. NCBI website.Available: https://www.ncbi.nlm.nih.gov/books/NBK45969/Accessed 2013 June 8.
10. Isaacman DJ, Burke BL, (2002) Utility of the serum C-reactive protein for detection of occult bacterial infection in children. Arch Pediatr Adolesc Med 156: 905-9.
11. Panero A, Pacifico L, Rossi N, Mancuso G, Stegagno M, et al. (1997) Interleukin-6 in neonates with early and late onset infection. Pediatr Infect Dis J 16: 370-375.
12. Buck C, Bundschu J, Gallati H, Bartmann P, Pohlandt F, (1994) Interleukin-6: A sensitive parameter for the early diagnosis of neonatal bacterial infection. Pediatrics 93: 54-58.
13. Messer J, Eyer D, Donato L, Gallati H, Matis J, et al. (1996) Evaluation of interleukin-6 and soluble receptors of tumor necrosis factor for early diagnosis of neonatal infection. J Pediatr 129: 574-580.
14. Lehrnbecher T, Schrod L, Kraus D, Roos T, Martius J, et al. (1995) Interleukin-6 and soluble interleukin-6 receptor in cord blood in the diagnosis of early onset sepsis in neonates. Acta Paediatr 84: 806-808.
15. Singh B, Merchant P, Walker CR, Kryworuchko M, Diaz-Mitoma F, (1996) Interleukin-6 expression in cord blood of patients with clinical chorioamnionitis. Pediatr Res 39: 976-979.
16. Krueger M, Nauck MS, Sang S, Hentschel R, Wieland H, et al. (2001) Cord blood levels of interleukin-6 and interleukin-8 for the immediate diagnosis of early-onset infection in premature infants. Biol Neonate. 80: 118-23.
17. Tasci Y, Dilbaz B, Uzmez Onal B, Caliskan E, Dilbaz S, et al. (2006) The value of cord blood interleukin-6 levels for predicting chorioamnionitis, funisitis and neonatal infection in term premature rupture of membranes. Eur J Obstet Gynecol Reprod Biol 128: 34-9.
18. Franz AR, Steinbach G, Kron M, Pohlandt F, (2001) Interleukin- 8- a valuable tool to restrict antibiotic therapy in newborn infants. Acta Pediatr 90: 125-32.
19. Mehr SS, Doyle LW, Rice GE, Vervaart P, Henschke P, (2001) Interleukin-6 and interleukin-8 in newborn bacterial infection. Am J Perinatol 18: 313-24.
20. Silveira RC, Procianoy RS, (1999) Evaluation of interleukin-6, tumour necrosis factor-alpha and interleukin-1beta for early diagnosis of neonatal sepsis. Acta Paediatr 88: 647-50.
21. Kurt AN, Aygun AD, Godekmerdan A, Kurt A, Dogan Y, et al. (2007) Serum IL-1beta, IL-6, IL-8, and TNF-alpha levels in early diagnosis and management of neonatal sepsis. Mediators Inflamm. 2007: 31397.
22. Akila P, Prashant V, Suma MN, Prashant SN, Chaitra TR, (2012) CD163 and its expanding functional repertoire. Clin Chim Acta 413: 669-674.
23. Zuwała-Jagiełło J, (2006) Haemoglobin scavenger receptor: function in relation to disease, Acta Biochimica Polonica 53: 257-268.
24. Groselj-Grenc M, Ihan A, Derganc M, (2008) Neutrophil and monocyte CD64 and CD163 expression in critically ill neonates and children with sepsis: comparison of fluorescence intensities and calculated indexes. Mediators Inflamm 2008: 202646.
25. Møller HJ, Moestrup SK, Weis N, Wejse C, Nielsen H, et al. (2006) Macrophage serum markers in pneumococcal bacteremia: prediction of survival by soluble CD163. Critical Care Medicine 34: 2561-2566.
26. Hintz KA, Rassias AJ, Wardwell K, Moss ML, Morganelli PM, et al. (2002) Endotoxin induces rapid metalloproteinase-mediated shedding followed by up-regulation of the monocyte hemoglobin scavenger receptor CD163. Journal of Leukocyte Biology 72: 711-717.