Zinc-Mediated Binding of Nucleic Acids to Amyloid-β Aggregates: Role of Histidine Residues

Journal of Alzheimer's Disease

Volumn 54, Issue 2, 2016, Pages 809-819

  Khmeleva, Svetlana A ^a,b   Radko, Sergey P ^a,b   Kozin, Sergey A ^a   Kiseleva, Yana Y ^b   Mezentsev, Yuri V ^b   Mitkevich, Vladimir A ^a   Kurbatov, Leonid K ^b   Ivanov, Alexis S ^b   Makarov, Alexander A ^a  

^a ENGELHARDT INSTITUTE OF MOLECULAR BIOLOGY   (Russian Federation)

^b INSTITUTE OF BIOMEDICAL CHEMISTRY   (Russian Federation)

Author keywords

Alzheimer's disease; amyloid peptide; DNA; histidine residues; RNA; zinc

Indexed keywords

AMYLOID BETA PROTEIN16; AMYLOID BETA PROTEIN[1-42]; DOUBLE STRANDED DNA; HISTIDINE; PROTEIN AGGREGATE; SINGLE STRANDED RNA; SYNTHETIC PEPTIDE; THIOFLAVINE; UNCLASSIFIED DRUG; ZINC ION; AMYLOID BETA PROTEIN; AMYLOID BETA-PROTEIN (1-16); AMYLOID BETA-PROTEIN (1-42); NUCLEIC ACID; PEPTIDE FRAGMENT; PROTEIN BINDING; ZINC;

ARTICLE; BETA SHEET; BINDING AFFINITY; CONTROLLED STUDY; DNA BINDING; FLUORESCENCE; HUMAN; HUMAN CELL; METAL BINDING; MOLECULE; NONHUMAN; PHOTON CORRELATION SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; RNA BINDING; SUBSTITUTION REACTION; HEP-G2 CELL LINE; METABOLISM; PHYSIOLOGY;

AMYLOID BETA-PEPTIDES; HEP G2 CELLS; HISTIDINE; HUMANS; NUCLEIC ACIDS; PEPTIDE FRAGMENTS; PROTEIN AGGREGATES; PROTEIN BINDING; ZINC;

EID: 84986612913     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-160415     Document Type: Article

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