Marrow stromal cells as universal donor cells for cardiac regenerative therapy: Fact or fancy?

Handbook of Cardiac Stem Cell Therapy

Volumn , Issue , 2008, Pages 117-137

  Luo, Jun ^a   Shum Tim, Dominique ^a   Chiu, Ray Chu Jeng ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84986570028     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1142/9781848162570_0008     Document Type: Chapter

References (56)

1. Herzenberg LA, Bianchi DW, Schroder J, et al. Fetal cells in the blood of pregnant women: detection and inrichment by fluorescence-activated cell sorting. Proc Natl Acad Sci USA 1979;76:1453-1455.
2. Bianchi DW, Zickwolf GK, Weil GJ, et al. Male fetal progenitor ells persist in maternal blood for as long as 27 years postpartum. Proc Natl Acad Sci USA 1996;93:705-708.
3. Ariga H, Ohto H, Busch MP, et al. Kinetics of fetal cellular and cell-free DNA in the circulation during and after pregnancy: implications for noninvasive prenatal diagnosis. Transfuion 2001;41:1524-1530.
4. Bianchi DW. Current knowledge about fetal blood cells in the maternal circulation. J Pediat Med 1998;26:175-185.
5. Liegeois A, Gaillard MC, Ouvre E, et al. Microchimerism in pregnant mice. Transplant Proc 1981;13:1250-1252.
6. Philip PJ, Ayraud N, Masseyeff R. Transfer, tissue localization and proliferation of fetal cells in pregnant mice. Immunol Lett 1982;4:175-178.
7. Johnson KL, Nelson JL, Furst DE, et al. Fetal cell microchimerism in tissue from multiple sites in women with systemic sclerosis. Arthritis Rheum 2001;44:1848-1854.
8. Invernizzi P, De Andreis C, Sirchia SM, et al. Blood fetal microchimerism in primary biliary cirrhosis. Clin Exp Immunol 2000;122:418-422.
9. TanakaA, Lindor K, Gish R, et al. Fetal microchimerism alone does not contribute to the induction of primary biliary cirrhosis. Hepatology 1999;30:833-838.
10. Srivatsa B, Srivasta S, Johnson KL, et al. Microchimerism of presumed fetal origin in thyroid specimens from women: a case-control study. Lancet 2001;358:2034-2038.
11. Tan XY, Liao H, Sun L, et al. Fetal microchimerism in the maternal mouse brain: a novel population of fetal progenitor or stem cells able to cross the blood-brain barrier? Stem Cells 2005;23:1443-1452.
12. Nelson JL, Furst DE, Maloney S, et al. Microchimerism and HLA-compatible relationships of pregnancy in scleroderma. Lancet 1998;351:559-562.
13. Endo Y, Negishi I, Ishikawa O. Possible contribution of microchimerism to the pathogenesis of Sjogren's syndrome. Rheumatology 2002;41:490-495.
14. Johnson KL, McAlindon TE, Mulcahy E, Bianchi DW. Microchimerism in a female patient with systemic lupus erythematosus. Arthritis Rheum 2001;43:4107-4111.
15. Klintschar M, Schwaiger P, Mannweiler S, et al. Evidence of fetal microchimerism in Hashimoto's thyroiditis. J Clin Endocrinol Metab 2001;86:2494-2498.
16. Khosrotehrani K, Bianchi DW. Fetal cell microchimerism: helpful or harmful to the parous woman? Curr Opin Obstet Gynecol 2003;15:195-199.
17. Artlett CM, Rasheed M, Russo-Stieglitz KE, et al. Influence of prior pregnancies on disease course and cause of death in systemic sclerosis. Ann Rheum Dis 2002;61: 346-350.
18. Johnson KL, Samura O, Nelson JL, et al. Significant fetal cell microchimerism in a nontransfused woman with hepatitis C: evidence of long-term survival and expansion. Hepatology 2002;36:1295-1297.
19. Chiu RCJ. Adult stem cell therapy for heart failure. Expert Opin Biol Ther 2003;3: 216-225.
20. Swijnenburg RJ, Tanaka M, Vogel H, Baker J, Kofidis T, Gunawan F, Lebl DR, Caffarelli AD, de Bruin JL, Fedoseyeva EV, Robbins RC. Embryonic stem cell immunogenicity increases upon differentiation after transplantation into ischemic myocardium. Circulation 2005;112:I166-I172.
21. Pittenger MF, Martin BJ. Mesenchymal stem cells and their potential as cardiac therapeutics. Circ Res 2004;95:9-20.
22. DebA, Wang S, Skelding KA, Miller D, Simper D, Caplice NM. Bone marrow-derived cardiomyocytes are present in adult human heart: a study of gender-mismatched bone marrow transplant patients. Circulation 2003;107:1247-1249.
23. Kajstura J, Rota M, Whang B, et al. Bone marrow cells differentiate in cardiac cell lineages after infarction independently of cell fusion. Circ Res 2005;96:127-137.
24. Terada N, Hamazaki T, Oka M, Hoki M, Mastalerz DM, NakanoY, Meyer EM, Morel L, Petersen BE, Scott EW. Bone marrow cells adopt the phenotype of other cells by spontaneous cell fusion. Nature 2002;416(6880):542-545.
25. Togel F, Fu Z, Weiss K, et al. Administered mesenchymal stem cells protect against ischemic acute renal failure through differentiation-independent mechanisms. Am J Physiol Renal Physiol 2005;289:F31-F42.
26. Sethe S, Scutt A, Stolzing A. Aging of mesenchyymal stem cells. Ageing Res Rev 2006;5:91-116.
27. Heeschen C, Lehmann R, Honold J, Assmus B, Aicher A, Walter DH, Martin H, Zeiher AM, Dimmeler S. Profoundly reduced neovascularization capacity of bone marrow mononuclear cells derived from patients with chronic ischemic heart disease. Circulation 2004;109:1615-1622.
28. Saito T, Kuang JQ, Bittira B, Al-Khaldi A, Chiu RCJ. Xenotransplant cardiac chimera: immune tolerance of adult stem cells. Ann Thorac Surg 2002;74(1):19-24.
29. MacDonald DJ, Saito T, Shum-Tim D, Duong M, Bernier PL, Chiu RCJ. Persistence of marrow stromal cells implanted into acutely infarcted myocardium: observations in a xenotransplant model. J Thorac Cardiovasc Surg 2005;130(4):1114-1121.
30. Amado LC, SaliarisAP, Schuleri KH, St John M, Xie J-S, Cattaneo S, Durand DJ, Fitton T, Kuang JQ, Stewart G, Lehrke S, Baumgartner WW, Martin BJ, Heldman AW, Hare JM. Cardiac repair with intramyocardial injection of allogeneic mesenchymal stem cells after myocardial infarction. Proc Natl Acad Sci USA 2005;102:11474-11479.
31. DaiW, Hale SL, Martin BJ, Kuang J-Q, Dow JS, Wold LE, Kloner RA. Allogeneic mesenchymal stem cell transplantation in postinfarcted rat myocardium: short- and long-term effects. Circulation 2005;112:214-223.
32. Grinnemo KH, ManssonA, Dellgren G, KlingbergD, Wardell E, DrvotaV, Tammik C, Holgersson J, Ringden D, Sylven C, Le Blanc K. Xenoreactivity and engraftment of human mesenchymal stem cells transplanted into infarcted rat myocardium. J Thorac Cardiovasc Surg 2004;127(5): 1293-1300.
33. Bittira B, Shum-Tim D, Al-Khaldi A, Chiu RC. Mobilization and homing of bone marrowstromal cells in myocardial infarction. Eur J Cardiothorac Surg 2003;24(3):393-398.
34. Caplan AI. Mesenchymal stem cells. J Orthop Res 1991;9(5):641-650.
35. Jaalouk DE, Eliopoulos N, Couture C, et al. Glucocorticoid-inducible retrovector for regulated transgene expression in genetically engineered bone marrow stromal cells. Hum Gene Ther 2000;11(13):1837-1849.
36. Pfaffl MW. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 2001;29(9):e45.
37. Liechty KW, MacKenzie TC, Shaaban AF, et al. Human mesenchymal stem cells engraft and demonstrate site-specific differentiation after in utero transplantation in sheep. Nat Med 2000;6(11):1282-1286.
38. Chiu RC. "Stealth immune tolerance" in stem cell transplantation: potential for "universal donors" in myocardial regenerative therapy. J Heart Lung Transplant 2005;24(5):511-516.
39. Becker M, Nitsche A, Neumann C, et al. Sensitive PCR method for the detection and realtime quantification of human cells in xenotransplantation systems. Br J Cancer 2002;87(11): 1328-1335.
40. Nitsche A, Becker M, Junghahn I, et al. Quantification of human cells in NOD/SCID mice by duplex real-time polymerase-chain reaction. Haematologica 2001;86(7): 693-699.
41. Fukuhara S, Tomita S, Yamashiro S, et al. Direct cell-cell interaction of cardiomyocytes is key for bone marrow stromal cells to go into cardiac lineage in vitro. J Thorac Cardiovasc Surg 2003;125(6):1470-1480.
42. Ryan JM, Barry FP, Murphy JM, Mahon BP. Mesenchymal stem cells avoid allogeneic rejection. J. Inflammation 2005;2:8.
43. Le Blanc K, Tammik C, Rosendahl K, et al. HLA expression and immunologic properties of differentiated and undifferentiated mesenchymal stem cells. Exp Hematol 2003;31(10):890-896.
44. Aggarwal S, Pittenger MF. Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood 2005;105(4):1815-1822.
45. Bartholomew A, Sturgeon C, Siatskas M, et al. Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo. Exp Hematol 2002;30(1):42-48.
46. Matzinger P. The danger model: a renewed sense of self. Science 2002;296(5566): 301-305.
47. Iwasaki A, Medzhitov R. Toll-like receptor control of the adaptive immune responses. Nat Immunol 2004;5:987-995.
48. Prince JM, Levy RM, Yang R, et al. Toll-like receptor-4 signaling mediates hepatic injury and systemic inflammation in hemorrhagic shock. J Am Coll Surg 2006;202:407-417.
49. Liu CT, Yang YJ, Yin F, et al. The immunobiological development of human bone marrow mesenchymal stem cells in the course of neuronal differentiation. Cell Immunol 2006;244: 19-32.
50. Jiang H, Chess L. Regulation of immune responses byTcells.NEngl J Med 2006;354:1166-1176.
51. Puissant B, Barreau C, Bourin P, et al. Immunomodulatory effect of human adipose tissuederived adult stem cells: comparison with bone marrow mesenchymal stem cells. Br J Haematol 2005;129:118-129.
52. Chang CJ, YenML, ChenYC, Chien CC, Huang HI, Bai CH, Yen BL. Placenta-derived multipotent cells exhibit immunosuppressive properties that are enhanced in the presence of interferon-γ. Stem cell 2006;24:2466-2477.
53. Min JY. Uamg Y, Sullivan MF, et al. Long-term improvement of cardiac function in rats after infarction by transplantation of embryonic stem cells. J Thorac Cardiovasc Surg 2003;125: 361-369.
54. Tsai MK, Ho HN, Chien HF, et al. The role of B7 ligands (CD80 and CD86) in CD152-mediated allograft tolerance: a crosscheck hypothesis. Transplantation 2004;77:48-54.
55. Li L, Baroja ML, Majumdar A, et al. Human embryonic stem cells possess immune-privileged properties. Stem Cells 2004;22:448-456.
56. Drukker M, Katchman H, Katz G, et al. Human embryonic stem cells and their differentiated derivatives are less susceptible for immune rejection than adult cells. Stem Cells 2006;24: 221-229.