The feasibility of progressive resistance training in women with polycystic ovary syndrome: A pilot randomized controlled trial

BMC Sports Science, Medicine and Rehabilitation

Volumn 8, Issue 1, 2016, Pages

  Vizza, Lisa ^a   Smith, Caroline A ^b   Swaraj, Soji ^c   Agho, Kingsley ^a   Cheema, Birinder S ^a,b  

^a UNIVERSITY OF WESTERN SYDNEY   (Australia)

^b WESTERN SYDNEY UNIVERSITY   (Australia)

^c Department of Microbiology and Infectious Diseases   (Australia)

Author keywords

Exercise; Menstrual cyclicity; Psychological health; Quality of life; Weight training

Indexed keywords

HEMOGLOBIN A1C; METFORMIN;

ADULT; ANXIETY DISORDER; ARTICLE; BODY MASS; BODY WEIGHT; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DEPRESSION; DEPRESSION ANXIETY STRESS SCALE; FAT FREE MASS; FEASIBILITY STUDY; FEMALE; HUMAN; MENSTRUAL CYCLE; OUTCOME ASSESSMENT; OVARY POLYCYSTIC DISEASE; PATIENT REFERRAL; PILOT STUDY; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; RESISTANCE TRAINING; SOCIAL INTERACTION; SOCIAL MEDIA; WAIST CIRCUMFERENCE;

EID: 84986308626     PISSN: None     EISSN: 20521847     Source Type: Journal    
DOI: 10.1186/s13102-016-0039-8     Document Type: Article

References (86)

1. March WA, Moore VM, Willson KJ, Phillips DIW, Norman RJ, Davies MJ. The prevalence of polycystic ovary syndrome in a community sample assessed under contrasting diagnostic criteria. Hum Reprod. 2010;25(2):544-51.
2. Rotterdam ESHRE/ASRM-sponsored PCOS Consensus Work-shop Group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil Steril. 2004;81(1):19-25.
3. Ehrmann DA. Polycystic ovary syndrome. N Engl J Med. 2005;352(12):1223-36.
4. Norman RJ, Dewailly D, Legro RS, Hickey TE. Polycystic ovary syndrome. 2007.
5. Giudice LC. Endometrium in PCOS: Implantation and predisposition to endocrine CA. Best Pract Res Clin Endocrinol Metab. 2006;20(2):235-44.
6. Gorry A, White DM, Franks S. Infertility in polycystic ovary syndrome. Endocrine. 2006;30(1):27-33.
7. Bhattacharya SM, Jha A. Prevalence and risk of depressive disorders in women with polycystic ovary syndrome (PCOS). Fertil Steril. 2010;94(1):357-9.
8. Deeks AA, Gibson-Helm ME, Teede HJ. Anxiety and depression in polycystic ovary syndrome: A comprehensive investigation. Fertil Steril. 2010;93(7):2421-3.
9. Himelein MJ, Thatcher SS. Depression and body image among women with polycystic ovary syndrome. J Health Psychol. 2006;11(4):613-25.
10. Barnard L, Ferriday D, Guenther N, Strauss B, Balen A, Dye L. Quality of life and psychological well being in polycystic ovary syndrome. Hum Reprod. 2007;22(8):2279-86.
11. Abazar E, Taghian F, Mardanian F, Forozandeh D. Effects of aerobic exercise on plasma lipoproteins in overweight and obese women with polycystic ovary syndrome. Adv Biomed Res. 2015;4:68.
12. Haqq L, McFarlane J, Dieberg G, Smart N. The effect of lifestyle intervention on body composition, glycaemic control and cardio-respiratory fitness in women with polycystic ovarian syndrome: A systematic review and meta-analysis. Int J Sport Nutr Exerc Metab. 2014;25(6):533-40.
13. Harrison CL, Lombard CB, Moran LJ, Teede HJ. Exercise therapy in polycystic ovary syndrome: A systematic review. Hum Reprod Update. 2011;17(2):171-83.
14. Harrison CL, Stepto NK, Hutchison SK, Teede HJ. The impact of intensified exercise training on insulin resistance and fitness in overweight and obese women with and without polycystic ovary syndrome. Clin Endocrinol (Oxf). 2012;76(3):351-7.
15. Hutchison S, Teede H, Rachoń D, Harrison C, Strauss B, Stepto N. Effect of exercise training on insulin sensitivity, mitochondria and computed tomography muscle attenuation in overweight women with and without polycystic ovary syndrome. Diabetologia. 2012;55(5):1424-34.
16. Hutchison SK, Stepto NK, Harrison CL, Moran LJ, Strauss BJ, Teede HJ. Effects of exercise on insulin resistance and body composition in overweight and obese women with and without polycystic ovary syndrome. J Clin Endocrinol Metab. 2011;96(1):E48-56.
17. Thomson RL, Buckley JD, Brinkworth GD. Exercise for the treatment and management of overweight women with polycystic ovary syndrome: A review of the literature. Obes Rev. 2011;12(5):e202-10.
18. Alliance PA. Evidence Based Guidelines for Assessment and Management of Polycystic Ovary Syndrome. Melbourne: Jean Hailes Foundation for Women's Health on behalf of the PCOS Australian Alliance; 2011.
19. Ciccolo J, Kraemer WJ. Resistance Training for the Prevention and Treatment of Chronic Disease. Boca Raton: CRC Press; 2013.
20. Tresierras M, Balady G. Resistance training in the treatment of diabetes and obesity: Mechanisms and outcomes. J Cardiopulm Rehabil Prev. 2009;29(2):67-75.
21. Strasser B, Schobersberger W. Evidence for resistance training as a treatment therapy in obesity. J Obes 2011. doi:10.1155/2011/482564.
22. Strasser B, Siebert U, Schobersberger W. Resistance training in the treatment of the metabolic syndrome. Sports Med. 2010;40(5):397-415.
23. Sigal R, Kenny G, Boulé N, Wells G, Prud'homme D, Fortier M, Reid R, Tulloch H, Coyle D, Phillips P et al. Effects of aerobic training, resistance training, or both on glycemic control in type 2 diabetes. Ann Intern Med. 2007;147:357-69.
24. Cheema BS, Vizza L, Swaraj S. Progressive resistance training in polycystic ovary syndrome: Can pumping iron improve clinical outcomes? Sports Med. 2014;44(9):1197-1207.
25. Hordern MD, Dunstan DW, Prins JB, Baker MK, Singh MAF, Coombes JS. Exercise prescription for patients with type 2 diabetes and pre-diabetes: A position statement from Exercise and Sport Science Australia. J Sci Med Sport. 2012;15(1):25-31.
26. Sharman JE, Stowasser M. Australian association for exercise and sports science position statement on exercise and hypertension. J Sci Med Sport. 2009;12(2):252-7.
27. Hayes S, Spence R, Galvao D, Newton R. Australian Association of Exercise and Sport Science position stand: Optimising cancer outcomes through exercise. J Sci Med Sport. 2009;12:428-34.
28. Donnelly J, Blair S, Jakicic J, Manore M, Rankin J, Smith B. American College of Sports Medicine Position Stand. Appropriate physical activity intervention strategies for weight loss and prevention of weight regain for adults. Med Sci Sports Exerc. 2009;41(2):459.
29. Selig SE, Levinger I, Williams AD, Smart N, Holland DJ, Maiorana A, Green DJ, Hare DL. Exercise & Sports Science Australia Position Statement on exercise training and chronic heart failure. J Sci Med Sport. 2010;13(3):288-94.
30. Colberg SR, Sigal RJ, Fernhall B, Regensteiner JG, Blissmer BJ, Rubin RR, Chasan-Taber L, Albright AL, Braun B. Exercise and type 2 diabetes: The American College of Sports Medicine and the American Diabetes Association: Joint position statement. Diabetes Care. 2010;33(12):e147-167.
31. Kraemer W, Adams K, Cafarelli E, Dudley G, Dooly C, Feigenbaum M, Fleck S, Franklin B, Fry A, Hoffman J et al. Progression models in resistance training for healthy adults. Med Sci Sports Exerc. 2002;34(2):364-80.
32. Almenning I, Rieber-Mohn A, Lundgren KM, Shetelig Løvvik T, Garnæs KK, Moholdt T. Effects of high intensity interval training and strength training on metabolic, cardiovascular and hormonal outcomes in women with polycystic ovary syndrome: A pilot study. PLoS One. 2015;10(9):e0138793.
33. Lara LAS, Ramos FKP, Kogure GS, Costa RS, Silva de Sá MF, Ferriani RA, Reis RM. Impact of Physical Resistance Training on the Sexual Function of Women with Polycystic Ovary Syndrome. J Sex Med. 2015;12(7):1584-1590.
34. Miranda-Furtado CL, Ramos FKP, Kogure GS, Santana-Lemos BA, Ferriani RA, Calado RT, dos Reis RM. A nonrandomized trial of progressive resistance training intervention in women with polycystic ovary syndrome and its implications in telomere content. Reprod Sci. 2015;23(5):644-54.
35. Fauser BCJM, Tarlatzis BC, Rebar RW, Legro RS, Balen AH, Lobo R, Carmina E, Chang J, Yildiz BO, Laven JSE et al. Consensus on women's health aspects of polycystic ovary syndrome (PCOS): The Amsterdam ESHRE/ASRM-Sponsored 3rd PCOS Consensus Workshop Group. Fertil Steril. 2012;97(1):28-38.e25.
36. De Jonge CJ, Barratt CL. Assisted reproductive technology: Accomplishments and new horizons. Cambridge: University Press; 2002. p. 274.
37. Thompson WR, Gordon NF, Pescatello LS. ACSM's guidelines for exercise testing and prescription. Philadelphia: Wolters Kluwer/Lippincott Williams & Wilkins; 2010.
38. Wessel TR, Arant CB, Olson MB, Johnson BD, Reis SE, Sharaf BL, Shaw LJ, Handberg E, Sopko G, Kelsey SF. Relationship of physical fitness vs body mass index with coronary artery disease and cardiovascular events in women. JAMA. 2004;292(10):1179-87.
39. Glickman SG, Marn CS, Supiano MA, Dengel DR. Validity and reliability of dual-energy X-ray absorptiometry for the assessment of abdominal adiposity. J Appl Physiol. 2004;97(2):509-14.
40. Cheema B, Abas H, Smith B, O'Sullivan A, Chan M, Patwardhan A, Kelly J, Gillin A, Pang G, Lloyd B et al. Progressive exercise for anabolism in kidney disease (PEAK): A randomized, controlled trial of resistance training during hemodialysis. J Am Soc Nephrol. 2007;18(5):1594-601.
41. Cronin L, Guyatt G, Griffith L, Wong E, Azziz R, Futterweit W, Cook D, Dunaif A. Development of a health-related quality-of-life questionnaire (PCOSQ) for women with polycystic ovary syndrome (PCOS) 1. J Clin Endocrinol Metab. 1998;83(6):1976-87.
42. Stewart AL, Greenfield S, Hays RD, Wells K, Rogers WH, Berry SD, McGlynn EA, Ware JE. Functional status and well-being of patients with chronic conditions: Results from the Medical Outcomes Study. JAMA. 1989;262(7):907-13.
43. Kroll T, Kehn M, Ho P-S, Groah S. The SCI exercise self-efficacy scale (ESES): Development and psychometric properties. Int J Behav Nutr Phys Act. 2007;4(1):34.
44. Perri MG, Martin AD, Leermakers EA, Sears SF, Notelovitz M. Effects of group-versus home-based exercise in the treatment of obesity. J Consult Clin Psychol. 1997;65(2):278.
45. Brown AJ, Setji TL, Sanders LL, Lowry KP, Otvos JD, Kraus WE, Svetkey PL. Effects of exercise on lipoprotein particles in women with polycystic ovary syndrome. Med Sci Sports Exerc. 2009;41(3):497-504.
46. Giallauria F, Palomba S, Maresca L, Vuolo L, Tafuri D, Lombardi G, Colao A, Vigorito C, Francesco O. Exercise training improves autonomic function and inflammatory pattern in women with polycystic ovary syndrome (PCOS). Clin Endocrinol (Oxf). 2008;69(5):792-8.
47. Palomba S, Giallauria F, Falbo A, Russo T, Oppedisano R, Tolino A, Colao A, Vigorito C, Zullo F, Orio F. Structured exercise training programme versus hypocaloric hyperproteic diet in obese polycystic ovary syndrome patients with anovulatory infertility: A 24-week pilot study. Hum Reprod. 2008;23(3):642-50.
48. Randeva HS, Lewandowski KC, Drzewoski J, Brooke-Wavell K, O'Callaghan C, Czupryniak L, Hillhouse EW, Prelevic GM. Exercise decreases plasma total homocysteine in overweight young women with polycystic ovary syndrome. J Clin Endocrinol Metab. 2002;87(10):4496-501.
49. Stener-Victorin E, Jedel E, Janson PO, Sverrisdottir YB. Low-frequency electroacupuncture and physical exercise decrease high muscle sympathetic nerve activity in polycystic ovary syndrome. Am J Physiol Regul Integr Comp Physiol. 2009;297(2):R387-95.
50. Bruner B, Chad K, Chizen D. Effects of exercise and nutritional counseling in women with polycystic ovary syndrome. Appl Physiol Nutr Metab. 2006;31(4):384-91.
51. Thomson RL, Buckley JD, Noakes M, Clifton PM, Norman RJ, Brinkworth GD. The effect of a hypocaloric diet with and without exercise training on body composition, cardiometabolic risk profile, and reproductive function in overweight and obese women with polycystic ovary syndrome. J Clin Endocrinol Metab. 2008;93(9):3373-80.
52. Vigorito C, Giallauria F, Palomba S, Cascella T, Manguso F, Lucci R, De Lorenzo A, Tafuri D, Lombardi G, Colao A et al. Beneficial effects of a three-month structured exercise training program on cardiopulmonary functional capacity in young women with polycystic ovary syndrome. J Clin Endocrinol Metab. 2007;92(4):1379-84.
53. Patel MX, Doku V, Tennakoon L. Challenges in recruitment of research participants. Adv Psychiatr Treat. 2003;9(3):229-38.
54. Campbell MK, Snowdon C, Francis D, Elbourne D, McDonald AM, Knight R, Entwistle V, Garcia J, Roberts I, Grant A et al. Recruitment to randomised trials: Strategies for trial enrollment and participation study. The STEPS study. Health Technol Assess. 2007, 11(48):iii, ix-105.
55. Blanton S, Morris DM, Prettyman MG, McCulloch K, Redmond S, Light KE, Wolf SL. Lessons learned in participant recruitment and retention: The EXCITE Trial. Phys Ther. 2006;86(11):1520-33.
56. Smith CA, Pirotta M, Kilbreath S. A feasibility study to examine the role of acupuncture to reduce symptoms of lymphoedema after breast cancer: A randomised controlled trial. Acupunct Med. 2014;32(5):387-93.
57. Nelson ME, Layne JE, Bernstein MJ, Nuernberger A, Castaneda C, Kaliton D, Hausdorff J, Judge JO, Buchner DM, Roubenoff R. The effects of multidimensional home-based exercise on functional performance in elderly people. J Gerontol A Biol Sci Med Sci. 2004;59(2):M154-60.
58. Mayoux-Benhamou MA, Roux C, Perraud A, Fermanian J, Rahali-Kachlouf H, Revel M. Predictors of compliance with a home-based exercise program added to usual medical care in preventing postmenopausal osteoporosis: An 18-month prospective study. Osteoporos Int. 2005;16(3):325-31.
59. Johnson CA, Corrigan SA, Dubbert PM, Gramling SE. Perceived barriers to excercise and weight control practices in community women. Women Health. 1990;16(3-4):177-91.
60. Chao D, Foy CG, Farmer D. Exercise adherence among older adults: Challenges and strategies. Control Clin Trials. 2000;21(5, Supplement 1):S212-7.
61. Dalle GR, Calugi S, Centis E, El GM, Marchesini G. Cognitive-behavioral strategies to increase the adherence to exercise in the management of obesity. J Obes. 2010;2011:348293.
62. Hillsdon M, Thorogood M. A systematic review of physical activity promotion strategies. Br J Sports Med. 1996;30(2):84-9.
63. Kozica SL, Lombard CB, Ilic D, Ng S, Harrison CL, Teede HJ. Acceptability of delivery modes for lifestyle advice in a large scale randomised controlled obesity prevention trial. BMC Public Health. 2015;15:699.
64. Lombard CB, Deeks AA, Ball K, Jolley D, Teede HJ. Weight, physical activity and dietary behavior change in young mothers: Short term results of the HeLP-her cluster randomized controlled trial. Nutr J. 2009;8:17-7.
65. Teede HJ, Misso ML, Deeks AA, Moran LJ, Stuckey BG, Wong JL, Norman RJ, Costello MF. Assessment and management of polycystic ovary syndrome: Summary of an evidence-based guideline. Med J Aust. 2011;195(6):S65-112.
66. Benson A, Torode M, Singh MF. The effect of high-intensity progressive resistance training on adiposity in children: A randomized controlled trial. Int J Obes (Lond). 2008;32(6):1016-27.
67. Dunstan DW, Daly RM, Owen N, Jolley D, de Courten M, Shaw J, Zimmet P. High-intensity resistance training improves glycemic control in older patients with type 2 diabetes. Diabetes Care. 2002;25(10):1729-36.
68. Lemmey AB, Marcora SM, Chester K, Wilson S, Casanova F, Maddison PJ. Effects of high-intensity resistance training in patients with rheumatoid arthritis: A randomized controlled trial. Arthritis Care Res. 2009;61(12):1726-34.
69. Seynnes O, Singh MAF, Hue O, Pras P, Legros P, Bernard PL. Physiological and functional responses to low-moderate versus high-intensity progressive resistance training in frail elders. J Gerontol A Biol Sci Med Sci. 2004;59(5):M503-9.
70. Singh NA, Quine S, Clemson LM, Williams EJ, Williamson DA, Stavrinos TM, Grady JN, Perry TJ, Lloyd BD, Smith EU. Effects of high-intensity progressive resistance training and targeted multidisciplinary treatment of frailty on mortality and nursing home admissions after hip fracture: A randomized controlled trial. J Am Med Dir Assoc. 2012;13(1):24-30.
71. Gordon B, Benson A, Bird S, et al. Resistance training improves metabolic health in type 2 diabetes: A systematic review. Diabetes Res Clin Pract. 2009; 83:157-75.
72. Castaneda C, Layne JE, Munoz-Orians L, Gordon PL, Walsmith J, Foldvari M, Roubenoff R, Tucker KL, Nelson ME. A randomized controlled trial of resistance exercise training to improve glycemic control in older adults with type 2 diabetes. Diabetes Care. 2002;25(12):2335-41.
73. Ishii T, Yamakita T, Sato T, Tanaka S, Fujii S. Resistance training improves insulin sensitivity in NIDDM subjects without altering maximal oxygen uptake. Diabetes Care. 1998;21(8):1353-5.
74. Stepto NK, Cassar S, Joham AE, Hutchison SK, Harrison CL, Goldstein RF, Teede HJ. Women with polycystic ovary syndrome have intrinsic insulin resistance on euglycaemic-hyperinsulaemic clamp. Hum Reprod. 2013.
75. Handelsman D, Wartofsky L. Requirement for mass spectrometry sex steroid assays in the Journal of Clinical Endocrinology and Metabolism. J Clin Endocrinol Metab. 2013;98(10):3971-3.
76. Brooks N, Layne JE, Gordon PL, Roubenoff R, Nelson ME, Castaneda-Sceppa C. Strength training improves muscle quality and insulin sensitivity in Hispanic older adults with type 2 diabetes. Int J Med Sci. 2007;4(1):19.
77. Kadoglou NP, Iliadis F, Angelopoulou N, Perrea D, Ampatzidis G, Liapis CD, Alevizos M. The anti-inflammatory effects of exercise training in patients with type 2 diabetes mellitus. Eur J Cardiovasc Prev Rehabil. 2007;14(6):837-43.
78. Kim ES, Im JA, Kim KC, Park JH, Suh SH, Kang ES, Kim SH, Jekal Y, Lee CW, Yoon YJ. Improved insulin sensitivity and adiponectin level after exercise training in obese Korean youth. Obesity. 2007;15(12):3023-30.
79. Yokoyama H, Emoto M, Araki T, Fujiwara S, Motoyama K, Morioka T, Koyama H, Shoji T, Okuno Y, Nishizawa Y. Effect of aerobic exercise on plasma adiponectin levels and insulin resistance in type 2 diabetes. Diabetes Care. 2004;27(7):1756-8.
80. Braith RW, Stewart KJ. Resistance exercise training: Its role in the prevention of cardiovascular disease. Circulation. 2006;113(22):2642-50.
81. Kraemer WJ, Ratamess NA, French DN. Resistance training for health and performance. Curr Sports Med Rep. 2002;1(3):165-71.
82. Dunstan D, Puddey I, Beilin L, Burke V, Morton A, Stanton K. Effects of a short-term circuit weight training program on glycaemic control in NIDDM. Diabetes Res Clin Pract. 1998;40(1):53-61.
83. Ibañez J, Izquierdo M, Argüelles I, Forga L, Larrión JL, García-Unciti M, Idoate F, Gorostiaga EM. Twice-weekly progressive resistance training decreases abdominal fat and improves insulin sensitivity in older men with type 2 diabetes. Diabetes Care. 2005;28(3):662-7.
84. Kogure GS, Silva RC, Picchi Ramos FK, Miranda-Furtado CL, Lara LA, Ferriani RA, Dos Reis RM. Women with polycystic ovary syndrome have greater muscle strength irrespective of body composition. Gynecol Endocrinol. 2015;31(3):237-42.
85. Banting LK, Gibson-Helm M, Polman R, Teede HJ, Stepto NK. Physical activity and mental health in women with Polycystic Ovary Syndrome. BMC Womens Health. 2014;14(1):1-9.
86. Conte F, Banting L, Teede HJ, Stepto NK. Mental health and physical activity in women with polycystic ovary syndrome: A brief review. Sports Med. 2015;45(4):497-504.