Beneficial effects of a three-month structured exercise training program on cardiopulmonary functional capacity in young women with polycystic ovary syndrome

Journal of Clinical Endocrinology and Metabolism

Volumn 92, Issue 4, 2007, Pages 1379-1384

  Vigorito, Carlo ^a   Giallauria, Francesco ^a   Palomba, Stefano ^b   Cascella, Teresa ^a   Manguso, Francesco ^a   Lucci, Rosa ^a   De Lorenzo, Anna ^a   Tafuri, Domenico ^c   Lombardi, Gaetano ^a   Colao, Annamaria ^a   Orio, Francesco ^a,c  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

^c UNIVERSITY OF NAPLES PARTHENOPE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BODY MASS; CARDIOPULMONARY FUNCTION; CARDIOVASCULAR RISK; CONTROLLED STUDY; EXERCISE; FEMALE; HIRSUTISM; HUMAN; INFERTILITY; INSULIN SENSITIVITY; MAJOR CLINICAL STUDY; OBESITY; OLIGOMENORRHEA; OVARY POLYCYSTIC DISEASE; OXYGEN CONSUMPTION; PRIORITY JOURNAL;

EID: 34147135722     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2006-2794     Document Type: Article

References (44)

1. Azziz R, Marin C, Hoq L, Badamgarav E, Song P 2005 Health care-related economic burden of the polycystic ovary syndrome during the reproductive life span. J Clin Endocrinol Metab 90:4650-4658
2. Lobo RA, Carmina E 2000 The importance of diagnosing the polycystic ovary syndrome. Ann Intern Med 132:989-993
3. Orio F, Palomba S, Colao A 2006 Cardiovascular risk in women with polycystic ovary syndrome. Fertil Steril 86:S20-S21
4. Ehrmann DA 2005 Polycystic ovary syndrome. N Engl J Med 352:1223-1236
5. De Fronzo R, Ferranini E 1991 Insulin-resistance: a multifaceted responsible for NIDDM, obesity, hypertension, dyslipidemia and atherosclerotic cardiovascular disease. Diabetes Care 14:173-194
6. Orio Jr F, Palomba S, Spinelli L, Cascella T, Tauchmanovà L, Zullo F, Lombardi G, Colao A 2004 The cardiovascular risk of young women with polycystic ovary syndrome: an observational, analytical, prospective casecontrol study. J Clin Endocrinol Metab 89:3696-3701
7. Orio Jr F, Palomba S, Cascella T, De Simone B, Di Biase S, Russo T, Labella D, Zullo F, Lombardi G, Colao A 2004 Early impairment of endothelial structure and function in young normal-weight women with polycystic ovary syndrome. J Clin Endocrinol Metab 89:4588-4593
8. Moran L, Norman RJ 2004 Understanding and managing disturbances in insulin metabolism and body weight in women with polycystic ovary syndrome. Best Pract Res Clin Obstet Gynaecol 18:719-736
9. Cussons AJ, Stuckey BG, Walsh JP, Burke V, Norman RJ 2005 Polycystic ovarian syndrome: marked differences between endocrinologists and gynaecologists in diagnosis and management. Clin Endocrinol (Oxf) 62:289-295
10. Holte J, Bergh T, Berne C, Wide L, Lithell H 1995 Restored insulin sensitivity but persistently increased early insulin secretion after weight loss in obese women with polycystic ovary syndrome. J Clin Endocrinol Metab 80:2586-2593
11. Andersen P, Seljeflot I, Abdelnoor M, Arnesen H, Dale PO, Lovik A, Birkeland K 1995 Increased insulin sensitivity and fibrinolytic capacity after dietary intervention in obese women with polycystic ovary syndrome. Metabolism 44:611-616
12. Diabetes Prevention Program Research Group 2002 Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 346:393-403
13. 1998 Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults. The evidence report. National Institutes of Health. Obes Res 6:51S-209S
14. Orio Jr F, Giallauria F, Palomba S, Cascella T, Manguso F, Vuolo L, Russo T, Tolino A, Lombardi G, Colao A, Vigorito C 2006 Cardiopulmonary impairment in young women with polycystic ovary syndrome. J Clin Endocrinol Metab 91:2967-2971
15. Blair SN, Kohl 3rd HW, Paffenbarger Jr RS, Clark DG, Cooper KH, Gibbons LW 1989 Physical fitness and all-cause mortality. A prospective study of healthy men and women. JAMA 262:2395-2401
16. Kavanagh T, Mertens DJ,HammLF, Beyene J, Kennedy J, Corey P, Shephard RJ 2003 Peak oxygen intake and cardiac mortality in women referred for cardiac rehabilitation. J Am Coll Cardiol 42:2139-2143
17. Wild S, Pierpoint T, McKeigue P, Jacobs H 2000 Cardiovascular disease in women with polycystic ovary syndrome at long-term follow-up: a retrospective cohort study. Clin Endocrinol (Oxf) 52:595-600
18. Birsdall MA, Farquar CM, White HD 1997 Association between polycystic ovaries and extent of coronary artery disease in women having cardiac catheterization. Ann Intern Med 126:32-35
19. Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group 2004 Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil Steril 81:19-25
20. Carmina E, Orio F, Palomba S, Longo RA, Lombardi G, Lobo RA 2005 Ovarian size and blood flow in women with polycystic ovary syndrome and their correlations with endocrine parameters. Fertil Steril 84:413-419
21. Ferriman D, Gallwey JD 1961 Clinical assessment of body hair growth in women. J Clin Endocrinol Metab 21:1440-1447
22. Roeykens J, Rogers R, Meeusen R, Magnus L, Borms J, de Meirleir K 1998 Validity and reliability in a Flemish population of the WHO-MONICA Optional Study of Physical Activity Questionnaire. Med Sci Sports Exerc 30:1071-1075
23. Tai MM 1994 A mathematic model for the determination of total area under glucose tolerance and other metabolic curves. Diabetes Care 17:152-154
24. Wild RA, Painter PC, Coulson PB, Carruth KB, Ranney GB 1985 Lipoprotein lipid concentrations and cardiovascular risk in women with polycystic ovary syndrome. J Clin Endocrinol Metab 61:946-951
25. Orio Jr F, Palomba S, Cascella T, Di Biase S, Manguso F, Tauchmanova L, Nardo LG, Labella D, Savastano S, Russo T, Zullo F, Colao A, Lombardi G 2005 The increase of leukocytes as a new putative marker of low-grade chronic inflammation and early cardiovascular risk in polycystic ovary syndrome. J Clin Endocrinol Metab 90:2-5
26. Ainsworth BE, Haskell WL, Whitt MC, Irwin ML, Swartz AM, Strath SJ, O'Brien WL, Bassett Jr DR, Schmitz KH, Emplaincourt PO, Jacobs Jr DR, Leon AS 2000 Compendium of physical activities: an update of activity codes and MET intensities. Med Sci Sports Exerc 32:S498-S504
27. Cussons AJ, Stuckey BGA, Watts GF 2006 Cardiovascular disease in the polycystic ovary syndrome: new insights and perspectives. Atherosclerosis 185:227-239
28. Garvey WT, Maianu L, Zhu JH, Brechtel-Hook G, Wallace P, Baron AD 1998 Evidence for defects in the trafficking and translocation of GLUT4 glucose transporters in skeletal muscle as a cause of human insulin-resistance. J Clin Invest 101:2377-2386
29. Boirie Y, Short KR, Ahlman B, Charlton M, Nair KS 2001 Tissue-specific regulation of mitochondrial and cytoplasmic protein synthesis rates by insulin. Diabetes 50:2652-2658
30. Ryder JW, Chibalin AV, Zierath JR 2001 Intracellular mechanisms underlying increases in glucose uptake in response to insulin or exercise in skeletal muscle. Acta Physiol Scand 171:249-257
31. Fleg JL, Pina IL, Balady GJ, Chaitman BR, Fletcher B, Lavie C, Limacher MC, Stein RA, Williams M, Bazzarre T 2000 Assessment of functional capacity in clinical and research applications: an advisory from the Committee on Exercise, Rehabilitation, and Prevention, Council on Clinical Cardiology, American Heart Association. Circulation 102:1591-1597
32. Rosenthal M, Haskell WL, Solomon R, Widstrom A, Reaven GM 1983 Demonstration of a relationship between level of physical training and insulin stimulated glucose utilization in normal humans. Diabetes 32:408-411
33. Clausen JO, Borch-Johnsen K, Ibsen H, Bergman RN, Hougaard P, Winther K, Pedersen O 1996 Insulin sensitivity index, acute insulin response, and glucose effectiveness in a population-based sample of 380 young healthy Caucasians. Analysis of the impact of gender, body fat, physical fitness, and life-style factors. J Clin Invest 98:1195-1209
34. Booth FW, Chakravarty MV, Spangenburg EE 2002 Exercise and gene expression: physiological regulation of the human genome through physical activity. J Physiol 543:399-411
35. Savage BD, Petersen KF, Shulman GI 2005 Mechanisms of insulin-resistance in humans and possible links with inflammation. Hypertension 45:828-833
36. Orio Jr F, Palomba S, Giallauria F, Colao A, Vigorito C 2007 Impaired cardiopulmonary parameters in young women with polycystic ovary syndrome. Clin Endocrinol (Oxf) 66:152-153
37. Bruner B, Chad K, Chizen D 2006 Effects of exercise and nutritional counseling in women with polycystic ovary syndrome. Appl Physiol Nutr Metab 31:384-391
38. Hawley JA 2004 Exercise as a therapeutic intervention for the prevention and treatment of insulin-resistance. Diabetes Metab Res Rev 20:383-393
39. Ridker PM, Rifai N, Rose L, Buring JE, Cook NR 2002 Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events. N Engl J Med 347:1557-1565
40. Lakka TA, Lakka HM, Rankinen T, Leon AS, Rao DC, Skinner JS, Wilmore JH, Bouchard C 2005 Effect of exercise training on plasma levels of C-reactive protein in healthy adults: the HERITAGE Family Study. Eur Heart J 26:2018-2025
41. Kondo N, Nomura M, Nakaya Y, Ito S, Ohguro T 2005 Association of inflammatory marker and highly sensitive C-reactive protein with aerobic exercise capacity, maximum oxygen uptake and insulin-resistance in healthy middle-aged volunteers. Circ J 69:452-457
42. You T, Bernman DM, Ryan AS, Nicklas BJ 2004 Effects of hypocaloric diet and exercise training on inflammation and adipocyte lipolysis in obese postmenopausal women. J Clin Endocrinol Metab 89:1739-1746
43. Stampfer MJ, Hu FB, Manson JE, Rimm EB, Willet WC 2000 Primary prevention of coronary heart disease in women through diet and lifestyle. N Engl J Med 343:16-22
44. Laaksonen DF, Lakka HM, Salonen JT, Niskanen LK, Rauramaa R, Lakka TA 2002 Low levels of leisure-time physical activity and cardiorespiratory fitness predict development of the metabolic syndrome. Diabetes Care 25:1612-1618