Euonymus alatus: A Review on Its Phytochemistry and Antidiabetic Activity

Evidence-based Complementary and Alternative Medicine

Volumn 2016, Issue , 2016, Pages

  Zhai, Xifeng ^a,b   Lenon, George Binh ^a   Xue, Charlie C L ^a   Li, Chun Guang ^a,c  

^a RMIT UNIVERSITY   (Australia)

^b XI'AN MEDICAL UNIVERSITY   (China)

^c WESTERN SYDNEY UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALOID DERIVATIVE; CARDENOLIDE DERIVATIVE; FLAVONOID; LIGNAN DERIVATIVE; PHENOL DERIVATIVE; PLANT EXTRACT; STEROID; TERPENOID DERIVATIVE;

ANTIDIABETIC ACTIVITY; ARTICLE; CONTROLLED CLINICAL TRIAL (TOPIC); DRUG IDENTIFICATION; DRUG ISOLATION; DRUG STRUCTURE; EUONYMUS; EUONYMUS ALATUS; HUMAN; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PHYTOCHEMISTRY;

EID: 84985995147     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1155/2016/9425714     Document Type: Article

References (58)

1. Jiangsu New Medical College, Dictionary of Chinese Materia Medica, Guijianyu, Shanghai Scientific and Technical Publishers, Shanghai, China, 1986.
2. Research Group, "The preliminary study on the pharmacological effects Euonymus alatus, " Journal of Traditional Chinese Medicine, vol. 4, pp. 28-30, 1977.
3. S. Kitanaka, M. Takido, K. Mizoue, and S. Nakaike, "Cytotoxic cardenolides from woods of Euonymus alata, " Chemical and Pharmaceutical Bulletin, vol. 44, no. 3, pp. 615-617, 1996.
4. Z. F. Fang, Studies on the Chemical Constituents and Antitumor Activities of Euonymus alatus, Shenyang Pharmaceutical University, Shenyang, China, 2007.
5. W. Wang, J. Wang, D. Zhao, H. Liu, W. Zhou, and K. Chen, "Comparison of Spatholobus suberectus Dum, Euonymus alatus (Thunb.) Sieb. and Eupolyphaga sinensisWalker on regulation of plasma lipid, " China Journal of Chinese Materia Medica, vol. 16, no. 5, pp. 299-320, 1991.
6. F. Qi, G. S. Liu, J. Yu et al., "Euonymus alatus effects on blood glucose and blood lipids of experimental diabetic mice, " Chinese Journal of Information on Traditional Chinese Medicine, vol. 5, no. 7, pp. 19-20, 1998.
7. D.-B. Huang, "An experimental research on inhibition of immediate and delayed type hypersensitivity by the 70% ethanolic extract from euonymus alatus, " Chinese Pharmacological Bulletin, vol. 19, no. 6, pp. 686-688, 2003.
8. S. M. Lang, D. N. Zhu, B.Y. Yu, J. L. Zhao, Q. J. Wang, and Y.Q. Yang, "Hypoglycemic effects of extracts and constituents from Euonymus alatus, " Journal of China Pharmaceutical University, vol. 34, no. 2, pp. 128-131, 2003.
9. Z. L. Qi, M. W. Bai, P. Bai et al., "Observation of Fufang euonymus alatus mixture in the treatment of chronic nephritis, " Henan Journal of Preventive Medicine, vol. 11, no. 1, p. 64, 2000.
10. L. G. Ye and H. G. Zhou, "Examples of Euonymus alatus application, " The Journal of New Chinese Medicine, vol. 35, no. 1, pp. 62-63, 2003.
11. Z. E. Piao, "Clinical observation of Euonymus alatus in the treatment of cor pulmonale, " Heilongjiang Medical Journal, vol. 2, no. 3, pp. 4-6, 1978.
12. Y. P. Yang and Y. M. Xiu, "Synchronous observation of the effects of Juanxiao tang for thromboxane B2/6-keto-PGF1α and superoxide dismutase in patients with asthma, " Journal of Jiangxi University of TraditionalChineseMedicine, vol. 8, pp. 29-30, 1996.
13. X. B. Dong, "Clinical observation of treatment of allergic disease with Euonymus alatus, " Journal of Traditional ChineseMedicine, vol. 4, p. 39, 1978.
14. H. S. Yan, "The clinical application of Euonymus alatus, " Primary Journal of ChineseMaterialMedicine, no. 1, p. 48, 1992.
15. D. Chang, X. L. Li, and J. S. Nan, "Primary observation of clearing heat and freeing strangury effects of Euonymus alatus, " China Journal of Chinese Materia Medica, vol. 25, no. 2, article 125, 2000.
16. L. L. Dong, X. G. Bu, Y. T. Mu et al., "Determination of total flavonoids in different parts of Euonymus alatus, " Information on Traditional Chinese Medicine, no. 6, p. 41, 1997.
17. Y. Zhang, G. Xiao, L. Sun, Y. Wang, Y. Wang, and Y. Wang, "A new flavan-3-ol lactone and other constituents from Euonymus alatus with inhibitory activities on α-glucosidase and differentiation of 3T3-L1 cells, " Natural Product Research, vol. 27, no. 17, pp. 1513-1520, 2013.
18. Y. Y. Ba, R. B. Shi, Q. Y. Liu et al., "Chemical compositions of Guijianyu (Ramulus Euonymi Alatae), " Journal of Beijing University of Chinese Medicine, vol. 35, no. 7, pp. 480-483, 2012.
19. K. Chen, D. J. Pan, and G. Y. Xu, "Flavonoid constituents in Euonymus alatus, " Chinese Traditional and Herbal Drugs, vol. 17, no. 3, pp. 1-3, 1986.
20. Y. F. Shen, K. Q. Lin, D. Y. Zhu et al., "Study on active constituents of euonymus alatus, " Journal of Hebei Medical University, no. 4, pp. 1-3, 1982.
21. Y. Liu, X. Zhou, X. J. Gong et al., "Studies on chemical constituents of Euonymus alatus (Thunb.) Sieb. III, " Chinese Traditional and Herbal Drugs, vol. 41, no. 11, pp. 1780-1781, 2010.
22. S.-Y. Jeong, P.-H. Nguyen, B.-T. Zhao et al., "Chemical constituents of Euonymus alatus (Thunb.) Sieb. and their PTP1B and α-glucosidase inhibitory activities, " Phytotherapy Research, vol. 29, no. 10, pp. 1540-1548, 2015.
23. L. Zhang, Y. Zou, X.-S. Ye, J. Zhang, W.-K. Zhang, and P. Li, "Chemical constituents from twigs of Euonymus alatus, " China Journal of ChineseMateriaMedica, vol. 40, no. 13, pp. 2612-2616, 2015.
24. Y. Liu, X. Zhou, and X. J. Gong, "Studies on chemical constituents of Euonymus alatus (Thunb.) Sieb. I, " West China Journal of Pharmaceutical Sciences, vol. 24, no. 2, pp. 107-109, 2009.
25. X. Zhou, Y. Liu, and X. J. Gong, "Studies on chemical constituents of Euonymus alatus (Thunb.) Sieb. II, " Chinese Pharmaceutical Journal, vol. 44, no. 18, pp. 1375-1377, 2009.
26. H. R. Kang, H. J. Eom, S. R. Lee et al., "Bioassay-guided isolation of antiproliferative triterpenoids from Euonymus alatus twigs, " Natural Product Communications, vol. 10, no. 11, pp. 1929-1932, 2015.
27. Z.-H. Yan, Z.-Z. Han, X.-Q. Hu et al., "Two new sesquiterpenes from Euonymus alatus, " Helvetica Chimica Acta, vol. 96, no. 1, pp. 85-92, 2013.
28. H. Ishiwata, Y. Shizuri, and K. Yamada, "Three sesquiterpene alkaloids from Euonymus alatus forma Striatus, " Phytochemistry, vol. 22, no. 12, pp. 2839-2841, 1983.
29. E. J. Jeong, J. H. Cho, S. H. Sung, S. Y. Kim, and Y. C. Kim, "Inhibition of nitric oxide production in lipopolysaccharidestimulated RAW264.7 macrophage cells by lignans isolated from Euonymus alatus leaves and twigs, " Bioorganic and Medicinal Chemistry Letters, vol. 21, no. 8, pp. 2283-2286, 2011.
30. Y. Liu, X. Zhou, and Z. N. Yang, "Study on chemical components of essential oil from Evonymus alata by GC-MS, " Cjtcmp Magazines, vol. 24, no. 10, pp. 1293-1295, 2009.
31. W. J. Xia, H. B. Cheng, and L. Zhang, "Experimental study on treatment of type-2 diabetes with Euonymus alatus, " Shaanxi Journal of Traditional Chinese Medicine, vol. 22, no. 8, pp. 505-507, 2001.
32. J. E. Li, L. Wang, L. L. Qin et al., "Effects of winged euonymus twig on insulin resisitance and adipo-cytokines in T2DM rats, " Guiding Journal of Traditional Chinese Medicine and Pharmacy, vol. 16, no. 11, pp. 1-3, 2010.
33. S. H. Park, S. K. Ko, and S. H. Chung, "Euonymus alatus prevents the hyperglycemia and hyperlipidemia induced by high-fat diet in ICR mice, " Journal of Ethnopharmacology, vol. 102, no. 3, pp. 326-335, 2005.
34. M. M. Zhao, M. Z. Xie, L. D. Li et al., "Effect of Euonymus alatus on islet β-cell in type 2 diabetic rats, " Journal of Hunan University of Traditional ChineseMedicine, vol. 30, no. 3, pp. 14-16, 2010.
35. B. Chang, C. Jin, W. Zhang et al., "Euonymus alatus in the treatment of diabetic nephropathy in rats, " American Journal of Chinese Medicine, vol. 40, no. 6, pp. 1177-1187, 2012.
36. Y. B. Li, H. T. Chang, P. Li et al., "The inhibitory effect of different extraction parts of 21 kinds of traditional Chinese medicine to human aldose reductase, " Journal of Peking University (Health Sciences), vol. 36, no. 1, pp. 107-108, 2004.
37. X.-K. Fang, Y. Gao, H.-Y. Yang et al., "Alleviating effects of active fraction of Euonymus alatus abundant in flavonoids on diabetic mice, " American Journal of Chinese Medicine, vol. 36, no. 1, pp. 125-140, 2008.
38. Y. J. Li, M. X. Gong, Y. Y. Lai et al., "Pharmacological effects of different extract fractions fromGuijianyu (Euonymus alatus) on diabetic rats, " Journal of Beijing University of Chinese Medicine, vol. 33, no. 3, pp. 179-182, 2010.
39. Y. H. Chen, M. X. Gong, X. R. Lu et al., "Study on the constituents from Euonymus alatus in hypoglycemic effective extract, " Chinese Journal of Experimental Traditional Medical Formulae, vol. 16, no. 7, pp. 42-43, 2010.
40. L. Costantino, G. Rastelli, P. Vianello, G. Cignarella, and D. Barlocco, "Diabetes complications and their potential prevention: aldose reductase inhibition and other approaches, " Medicinal Research Reviews, vol. 19, no. 1, pp. 3-23, 1999.
41. X.-K. Fang, J. Gao, and D.-N. Zhu, "Kaempferol and quercetin isolated from Euonymus alatus improve glucose uptake of 3T3-L1 cells without adipogenesis activity, " Life Sciences, vol. 82, no. 11-12, pp. 615-622, 2008.
42. M. D. Ivorra, M. P. D'Ocon, M. Paya, and A. Villar, "Antihyperglycemic and insulin-releasing effects of β-sitosterol 3-β-D-glucoside and its aglycone, β-sitosterol, " Archives Internationales de Pharmacodynamie et deTherapie, vol. 296, pp. 224-231, 1988.
43. Y. Cai, C. Fan, J. Yan, N. Tian, and X. Ma, "Effects of rutin on the expression of PPARγ in skeletal muscles of db/db mice, " Planta Medica, vol. 78, no. 9, pp. 861-865, 2012.
44. H. M. Li, J. K. Kim, J. M. Jang, C. B. Cui, and S. S. Lim, "Analysis of the inhibitory activity of Abeliophyllum distichum leaf constituents against aldose reductase by using high-speed counter current chromatography, " Archives of Pharmacal Research, vol. 36, no. 9, pp. 1104-1112, 2013.
45. S. D. Varma, I. Mikuni, and J. H. Kinoshita, "Flavonoids as inhibitors of lens aldose reductase, " Science, vol. 188, no. 4194, pp. 1215-1216, 1975.
46. I. Aydogdu, F. Zihnioglu, T. Karayildirim, D. Gülcemal, O. Alankuş-Çalişkan, and E. Bedir, "α-Glucosidase inhibitory constituents of Linaria kurdica subsp. eriocalyx, " Natural Product Communications, vol. 5, no. 6, pp. 841-844, 2010.
47. Z. M. Zhao, "Clinical observation of compound Euonymus alatus preparation in the treatment of patients with impaired glucose tolerance, " HebeiMedical Journal, vol. 34, no. 23, p. 3658, 2012.
48. Z. F. Fang, Z. L. Li, Y. Wang et al., "Studies on chemical constituents fromEuonymus alatus II, " China Journal of Chinese Materia Medica, vol. 33, no. 12, pp. 1422-1424, 2008.
49. E. J. Jeong, H. Yang, S. H. Kim, S. Y. Kang, S. H. Sung, and Y. C. Kim, "Inhibitory constituents of Euonymus alatus leaves and twigs on nitric oxide production in BV2 microglia cells, " Food and Chemical Toxicology, vol. 49, no. 6, pp. 1394-1398, 2011.
50. Y. Y. Ba, Q. Y. Liu, R. B. Shi, and L. Z. Zhang, "Studies on flavonoids from Euonymus alatus, " Chinese Traditional and Herbal Drugs, vol. 43, no. 2, pp. 242-246, 2012.
51. Z. Y. Jiang, W. H. Zhou, S. H. Lu et al., "Studies on the chemical constituents of the Chinese drug 'Gui Jian Yu' I, " Journal of Nanjing College of Pharmacy, vol. 19, no. 2, pp. 93-95, 1982.
52. Z. F. Fang, Z. L. Li, Y. Wang, W. Li, and H. M. Hua, "Chemical constituents from wing twigs of Euonymus alatus, " Chinese Traditional and Herbal Drugs, vol. 38, no. 6, pp. 810-812, 2007.
53. W.-H. Park, S.-H. Kim, and C.-H. Kim, "A new matrix metalloproteinase-9 inhibitor 3, 4-dihydroxycinnamic acid (caffeic acid) from methanol extract of Euonymus alatus: isolation and structure determination, " Toxicology, vol. 207, no. 3, pp. 383-390, 2005.
54. U.-H. Jin, J.-Y. Lee, S.-K. Kang et al., "A phenolic compound, 5-caffeoylquinic acid (chlorogenic acid), is a new type and strong matrix metalloproteinase-9 inhibitor: isolation and identification from methanol extract of Euonymus alatus, " Life Sciences, vol. 77, no. 22, pp. 2760-2769, 2005.
55. S. K. Sui and X. G. Li, "Clinical observation of 57 cases diabetes treated from blood stasis theory, " Chinese Journal of Integrated Traditional andWesternMedicine, vol. 12, no. 1, pp. 43-44, 1992.
56. W. Y. Wu, "8805 Yuxiao powder add and subtract treatment of 58 cases of type 2 diabetes, " Beijing Journal of TraditionalChinese Medicine, no. 3, p. 46, 1992.
57. Y. J. Zhu, "Clinical observation of 100 cases of type 2 diabetes treated fromthe theory of liver, " Shanghai Journal of Traditional Chinese Medicine, no. 7, pp. 19-20, 1999.
58. J. Q. Hu and Y. Zhen, "The treatment of diabetes using Shenqi Maiwei Dihuang decoction with heavy added euonymus alatus, " Chinese Journal of Ethnomedicine and Ethnopharmacy, vol. 9, no. 4, pp. 209-210, 2000.