-
1
-
-
71549144079
-
Cancers of the ampulla of vater: Demographics, morphology, and survival based on 5, 625 cases from the SEER program
-
Albores-Saavedra J, Schwartz AM, Batich K and Henson DE: Cancers of the ampulla of vater: Demographics, morphology, and survival based on 5, 625 cases from the SEER program. J Surg Oncol 100:598-605, 2009.
-
(2009)
J Surg Oncol
, vol.100
, pp. 598-605
-
-
Albores-Saavedra, J.1
Schwartz, A.M.2
Batich, K.3
Henson, D.E.4
-
2
-
-
84910031461
-
Bile acid dysregulation, gut dysbiosis, and gastrointestinal cancer
-
Tsuei J, Chau T, Mills D and Wan YJ: Bile acid dysregulation, gut dysbiosis, and gastrointestinal cancer. Exp Biol Med 239:1489-1504, 2014.
-
(2014)
Exp Biol Med
, vol.239
, pp. 1489-1504
-
-
Tsuei, J.1
Chau, T.2
Mills, D.3
Wan, Y.J.4
-
3
-
-
0035214782
-
Risk of adenocarcinomas of the esophagus and gastric cardia in patients with gastroesophageal reflux diseases and after antireflux surgery
-
Ye W, Chow WH, Lagergren J, Yin L and Nyrén O: Risk of adenocarcinomas of the esophagus and gastric cardia in patients with gastroesophageal reflux diseases and after antireflux surgery. Gastroenterology 121:1286-1293, 2001.
-
(2001)
Gastroenterology
, vol.121
, pp. 1286-1293
-
-
Ye, W.1
Chow, W.H.2
Lagergren, J.3
Yin, L.4
Nyrén, O.5
-
4
-
-
33645978716
-
Bile acid promotes the proliferation of squamous cell carcinoma of the esophagus, independent of its inducing COX-2 expression
-
Nishioka K, Doki Y, Miyata H, Tamura S, Yasuda T, Kimura Y, Kishi K, Yoshida K, Fujiwara Y, Yano M, et al: Bile acid promotes the proliferation of squamous cell carcinoma of the esophagus, independent of its inducing COX-2 expression. J Surg Res 132:130-135, 2006.
-
(2006)
J Surg Res
, vol.132
, pp. 130-135
-
-
Nishioka, K.1
Doki, Y.2
Miyata, H.3
Tamura, S.4
Yasuda, T.5
Kimura, Y.6
Kishi, K.7
Yoshida, K.8
Fujiwara, Y.9
Yano, M.10
-
5
-
-
84858821206
-
Bile acids: Promoters or carcinogens in colon cancer?
-
Bernstein C, Payne CM and Bernstein H: Bile acids: Promoters or carcinogens in colon cancer? J Carcinogene Mutagene 2:101e. doi:10.4172/2157-2518.1000101e, 2011.
-
(2011)
J Carcinogene Mutagene
, vol.2
, pp. 101e
-
-
Bernstein, C.1
Payne, C.M.2
Bernstein, H.3
-
6
-
-
70349570937
-
Hydrophobic bile acids, genomic instability, Darwinian selection, and colon carcinogenesis
-
Payne CM, Bernstein C, Dvorak K and Bernstein H: Hydrophobic bile acids, genomic instability, Darwinian selection, and colon carcinogenesis. Clin Exp Gastroenterol 1:19-47, 2008.
-
(2008)
Clin Exp Gastroenterol
, vol.1
, pp. 19-47
-
-
Payne, C.M.1
Bernstein, C.2
Dvorak, K.3
Bernstein, H.4
-
7
-
-
27544447260
-
Glycochenodeoxycholate plays a carcinogenic role in immortalized mouse cholangiocytes via oxidative DNA damage
-
Komichi D, Tazuma S, Nishioka T, Hyogo H and Chayama K: Glycochenodeoxycholate plays a carcinogenic role in immortalized mouse cholangiocytes via oxidative DNA damage. Free Radic Biol Med 39:1418-1427, 2005.
-
(2005)
Free Radic Biol Med
, vol.39
, pp. 1418-1427
-
-
Komichi, D.1
Tazuma, S.2
Nishioka, T.3
Hyogo, H.4
Chayama, K.5
-
8
-
-
0036208350
-
Bile acids induce cyclooxygenase-2 expression via the epidermal growth factor receptor in a human cholangiocarcinoma cell line
-
Yoon JH, Higuchi H, Werneburg NW, Kaufmann SH and Gores GJ: Bile acids induce cyclooxygenase-2 expression via the epidermal growth factor receptor in a human cholangiocarcinoma cell line. Gastroenterology 122:985-993, 2002.
-
(2002)
Gastroenterology
, vol.122
, pp. 985-993
-
-
Yoon, J.H.1
Higuchi, H.2
Werneburg, N.W.3
Kaufmann, S.H.4
Gores, G.J.5
-
9
-
-
48749113401
-
Targeting bile-acid signalling for metabolic diseases
-
Thomas C, Pellicciari R, Pruzanski M, Auwerx J and Schoonjans K: Targeting bile-acid signalling for metabolic diseases. Nat Rev Drug Discov 7:678-693, 2008.
-
(2008)
Nat Rev Drug Discov
, vol.7
, pp. 678-693
-
-
Thomas, C.1
Pellicciari, R.2
Pruzanski, M.3
Auwerx, J.4
Schoonjans, K.5
-
10
-
-
84859101637
-
Expression of the nuclear bile acid receptor/farnesoid X receptor is reduced in human colon carcinoma compared to nonneoplastic mucosa independent from site and may be associated with adverse prognosis
-
Lax S, Schauer G, Prein K, Kapitan M, Silbert D, Berghold A, Berger A and Trauner M: Expression of the nuclear bile acid receptor/farnesoid X receptor is reduced in human colon carcinoma compared to nonneoplastic mucosa independent from site and may be associated with adverse prognosis. Int J Cancer 130:2232-2239, 2012.
-
(2012)
Int J Cancer
, vol.130
, pp. 2232-2239
-
-
Lax, S.1
Schauer, G.2
Prein, K.3
Kapitan, M.4
Silbert, D.5
Berghold, A.6
Berger, A.7
Trauner, M.8
-
11
-
-
79951595623
-
Differential expression of the nuclear receptors farnesoid X receptor (FXR) and pregnane X receptor (PXR) for grading dysplasia in patients with Barrett's oesophagus
-
Van De Winkel A, Van Zoest KP, Van Dekken H, Moons LM, Kuipers EJ and Van Der Laan LJ: Differential expression of the nuclear receptors farnesoid X receptor (FXR) and pregnane X receptor (PXR) for grading dysplasia in patients with Barrett's oesophagus. Histopathology 58:246-253, 2011.
-
(2011)
Histopathology
, vol.58
, pp. 246-253
-
-
Van De Winkel, A.1
Van Zoest, K.P.2
Van Dekken, H.3
Moons, L.M.4
Kuipers, E.J.5
Van Der Laan, L.J.6
-
12
-
-
34447098081
-
Spontaneous hepatocarcinogenesis in farnesoid X receptor-null mice
-
Kim I, Morimura K, Shah Y, Yang Q, Ward JM and Gonzalez FJ: Spontaneous hepatocarcinogenesis in farnesoid X receptor-null mice. Carcinogenesis 28:940-946, 2007.
-
(2007)
Carcinogenesis
, vol.28
, pp. 940-946
-
-
Kim, I.1
Morimura, K.2
Shah, Y.3
Yang, Q.4
Ward, J.M.5
Gonzalez, F.J.6
-
13
-
-
79957663467
-
The G protein-coupled bile acid receptor, TGR5, stimulates gallbladder filling
-
Li T, Holmstrom SR, Kir S, Umetani M, Schmidt DR, Kliewer SA and Mangelsdorf DJ: The G protein-coupled bile acid receptor, TGR5, stimulates gallbladder filling. Mol Endocrinol 25:1066-1071, 2011.
-
(2011)
Mol Endocrinol
, vol.25
, pp. 1066-1071
-
-
Li, T.1
Holmstrom, S.R.2
Kir, S.3
Umetani, M.4
Schmidt, D.R.5
Kliewer, S.A.6
Mangelsdorf, D.J.7
-
14
-
-
69149083245
-
TGR5-mediated bile acid sensing controls glucose homeostasis
-
Thomas C, Gioiello A, Noriega L, Strehle A, Oury J, Rizzo G, Macchiarulo A, Yamamoto H, Mataki C, Pruzanski M, et al: TGR5-mediated bile acid sensing controls glucose homeostasis. Cell Metab 10:167-177, 2009.
-
(2009)
Cell Metab
, vol.10
, pp. 167-177
-
-
Thomas, C.1
Gioiello, A.2
Noriega, L.3
Strehle, A.4
Oury, J.5
Rizzo, G.6
Macchiarulo, A.7
Yamamoto, H.8
Mataki, C.9
Pruzanski, M.10
-
15
-
-
84895520482
-
The bile acid TGR5 membrane receptor: From basic research to clinical application
-
Duboc H, Taché Y and Hofmann AF: The bile acid TGR5 membrane receptor: From basic research to clinical application. Dig Liver Dis 46:302-312, 2014.
-
(2014)
Dig Liver Dis
, vol.46
, pp. 302-312
-
-
Duboc, H.1
Taché, Y.2
Hofmann, A.F.3
-
16
-
-
84874082742
-
Expression of bile acid receptor TGR5 in gastric adenocarcinoma
-
Cao W, Tian W, Hong J, Li D, Tavares R, Noble L, Moss SF and Resnick MB: Expression of bile acid receptor TGR5 in gastric adenocarcinoma. Am J Physiol Gastrointest Liver Physiol 304:G322-G327, 2013.
-
(2013)
Am J Physiol Gastrointest Liver Physiol
, vol.304
, pp. G322-G327
-
-
Cao, W.1
Tian, W.2
Hong, J.3
Li, D.4
Tavares, R.5
Noble, L.6
Moss, S.F.7
Resnick, M.B.8
-
17
-
-
77149120776
-
Role of a novel bile acid receptor TGR5 in the development of oesophageal adenocarcinoma
-
Hong J, Behar J, Wands J, Resnick M, Wang LJ, DeLellis RA, Lambeth D, Souza RF, Spechler SJ and Cao W: Role of a novel bile acid receptor TGR5 in the development of oesophageal adenocarcinoma. Gut 59:170-180, 2010.
-
(2010)
Gut
, vol.59
, pp. 170-180
-
-
Hong, J.1
Behar, J.2
Wands, J.3
Resnick, M.4
Wang, L.J.5
De Lellis, R.A.6
Lambeth, D.7
Souza, R.F.8
Spechler, S.J.9
Cao, W.10
-
18
-
-
84864383668
-
Chenodeoxycholic acid through a TGR5-dependent CREB signaling activation enhances cyclin D1 expression and promotes human endometrial cancer cell proliferation
-
Casaburi I, Avena P, Lanzino M, Sisci D, Giordano F, Maris P, Catalano S, Morelli C and Andò S: Chenodeoxycholic acid through a TGR5-dependent CREB signaling activation enhances cyclin D1 expression and promotes human endometrial cancer cell proliferation. Cell Cycle 11:2699-2710, 2012.
-
(2012)
Cell Cycle
, vol.11
, pp. 2699-2710
-
-
Casaburi, I.1
Avena, P.2
Lanzino, M.3
Sisci, D.4
Giordano, F.5
Maris, P.6
Catalano, S.7
Morelli, C.8
Andò, S.9
-
19
-
-
34547092697
-
Bile acid-induced TGR5-dependent c-Jun-N terminal kinase activation leads to enhanced caspase 8 activation in hepatocytes
-
Yang JI, Yoon JH, Myung SJ, Gwak GY, Kim W, Chung GE, Lee SH, Lee SM, Kim CY and Lee HS: Bile acid-induced TGR5-dependent c-Jun-N terminal kinase activation leads to enhanced caspase 8 activation in hepatocytes. Biochem Biophys Res Commun 361:156-161, 2007.
-
(2007)
Biochem Biophys Res Commun
, vol.361
, pp. 156-161
-
-
Yang, J.I.1
Yoon, J.H.2
Myung, S.J.3
Gwak, G.Y.4
Kim, W.5
Chung, G.E.6
Lee, S.H.7
Lee, S.M.8
Kim, C.Y.9
Lee, H.S.10
-
20
-
-
84873294643
-
Deficiency of G-protein-coupled bile acid receptor Gpbar1 (TGR5) enhances chemically induced liver carcinogenesis
-
Chen WD, Yu D, Forman BM, Huang W and Wang YD: Deficiency of G-protein-coupled bile acid receptor Gpbar1 (TGR5) enhances chemically induced liver carcinogenesis. Hepatology 57:656-666, 2013.
-
(2013)
Hepatology
, vol.57
, pp. 656-666
-
-
Chen, W.D.1
Yu, D.2
Forman, B.M.3
Huang, W.4
Wang, Y.D.5
-
21
-
-
79151483638
-
An online survival analysis tool to rapidly assess the effect of 22, 277 genes on breast cancer prognosis using microarray data of 1, 809 patients
-
Györffy B, Lánczky A, Eklund AC, Denkert C, Budczies J, Li Q and Szallasi Z: An online survival analysis tool to rapidly assess the effect of 22, 277 genes on breast cancer prognosis using microarray data of 1, 809 patients. Breast Cancer Res Treat 123:725-731, 2010.
-
(2010)
Breast Cancer Res Treat
, vol.123
, pp. 725-731
-
-
Györffy, B.1
Lánczky, A.2
Eklund, A.C.3
Denkert, C.4
Budczies, J.5
Li, Q.6
Szallasi, Z.7
-
22
-
-
84893181929
-
Online survival analysis software to assess the prognostic value of biomarkers using transcriptomic data in non-small-cell lung cancer
-
Gyorffy B, Surowiak P, Budczies J and Lanczky A: Online survival analysis software to assess the prognostic value of biomarkers using transcriptomic data in non-small-cell lung cancer. PLoS One 8:e82241.1-e82241.8, 2013.
-
(2013)
PLoS One
, vol.8
, pp. e822411-e822418
-
-
Gyorffy, B.1
Surowiak, P.2
Budczies, J.3
Lanczky, A.4
-
23
-
-
84860903681
-
Implementing an online tool for genome-wide validation of survival-associated biomarkers in ovarian-cancer using microarray data from 1287 patients
-
Gyorffy B, Lánczky A and Szállási Z: Implementing an online tool for genome-wide validation of survival-associated biomarkers in ovarian-cancer using microarray data from 1287 patients. Endocr Relat Cancer 19:197-208, 2012.
-
(2012)
Endocr Relat Cancer
, vol.19
, pp. 197-208
-
-
Gyorffy, B.1
Lánczky, A.2
Szállási, Z.3
-
24
-
-
84875740314
-
Integrative analysis of complex cancer genomics and clinical profiles using the cBio-Portal
-
Gao J, Aksoy BA, Dogrusoz U, Dresdner G, Gross B, Sumer SO, Sun Y, Jacobsen A, Sinha R, Larsson E, et al: Integrative analysis of complex cancer genomics and clinical profiles using the cBio-Portal. Sci Signal 6: pl1, 2013.
-
(2013)
Sci Signal
, vol.6
, pp. 1
-
-
Gao, J.1
Aksoy, B.A.2
Dogrusoz, U.3
Dresdner, G.4
Gross, B.5
Sumer, S.O.6
Sun, Y.7
Jacobsen, A.8
Sinha, R.9
Larsson, E.10
-
25
-
-
84866002291
-
The cBio cancer genomics portal: An open platform for exploring multidimensional cancer genomics data
-
Cerami E, Gao J, Dogrusoz U, Gross BE, Sumer SO, Aksoy BA, Jacobsen A, Byrne CJ, Heuer ML, Larsson E, et al: The cBio cancer genomics portal: An open platform for exploring multidimensional cancer genomics data. Cancer Discov 2:401-404, 2012.
-
(2012)
Cancer Discov
, vol.2
, pp. 401-404
-
-
Cerami, E.1
Gao, J.2
Dogrusoz, U.3
Gross, B.E.4
Sumer, S.O.5
Aksoy, B.A.6
Jacobsen, A.7
Byrne, C.J.8
Heuer, M.L.9
Larsson, E.10
-
26
-
-
0027377043
-
Immunohistochemical determination of estrogen and progesterone receptor content in human breast cancer. Computer-assisted image analysis (QIC score) vs. Subjective grading (IRS)
-
Remmele W and Schicketanz KH: Immunohistochemical determination of estrogen and progesterone receptor content in human breast cancer. Computer-assisted image analysis (QIC score) vs. subjective grading (IRS). Pathol Res Pract 189:862-866, 1993.
-
(1993)
Pathol Res Pract
, vol.189
, pp. 862-866
-
-
Remmele, W.1
Schicketanz, K.H.2
-
27
-
-
84938685582
-
Histomorphologic and molecular phenotypes predict gemcitabine response and overall survival in adenocarcinoma of the ampulla of Vater
-
Schiergens TS, Reu S, Neumann J, Renz BW, Niess H, Boeck S, Heinemann V, Bruns CJ, Jauch KW and Kleespies A: Histomorphologic and molecular phenotypes predict gemcitabine response and overall survival in adenocarcinoma of the ampulla of Vater. Surgery 158:151-161, 2015.
-
(2015)
Surgery
, vol.158
, pp. 151-161
-
-
Schiergens, T.S.1
Reu, S.2
Neumann, J.3
Renz, B.W.4
Niess, H.5
Boeck, S.6
Heinemann, V.7
Bruns, C.J.8
Jauch, K.W.9
Kleespies, A.10
-
28
-
-
77950548239
-
Loss of E-cadherin and beta-catenin is correlated with poor prognosis of ampullary neoplasms
-
Hsu HP, Shan YS, Jin YT, Lai MD and Lin PW: Loss of E-cadherin and beta-catenin is correlated with poor prognosis of ampullary neoplasms. J Surg Oncol 101:356-362, 2010.
-
(2010)
J Surg Oncol
, vol.101
, pp. 356-362
-
-
Hsu, H.P.1
Shan, Y.S.2
Jin, Y.T.3
Lai, M.D.4
Lin, P.W.5
-
29
-
-
84916238980
-
Nestin predicts a favorable prognosis in early ampullary adenocarcinoma and functions as a promoter of metastasis in advanced cancer
-
Shan YS, Chen YL, Lai MD and Hsu HP: Nestin predicts a favorable prognosis in early ampullary adenocarcinoma and functions as a promoter of metastasis in advanced cancer. Oncol Rep 33:40-48, 2015.
-
(2015)
Oncol Rep
, vol.33
, pp. 40-48
-
-
Shan, Y.S.1
Chen, Y.L.2
Lai, M.D.3
Hsu, H.P.4
-
30
-
-
84856121002
-
Effect of EpCAM, CD44, CD133 and CD166 expression on patient survival in tumours of the ampulla of Vater
-
Piscuoglio S, Lehmann FS, Zlobec I, Tornillo L, Dietmaier W, Hartmann A, Wünsch PH, Sessa F, Rümmele P, Baumhoer D, et al: Effect of EpCAM, CD44, CD133 and CD166 expression on patient survival in tumours of the ampulla of Vater. J Clin Pathol 65:140-145, 2012.
-
(2012)
J Clin Pathol
, vol.65
, pp. 140-145
-
-
Piscuoglio, S.1
Lehmann, F.S.2
Zlobec, I.3
Tornillo, L.4
Dietmaier, W.5
Hartmann, A.6
Wünsch, P.H.7
Sessa, F.8
Rümmele, P.9
Baumhoer, D.10
-
31
-
-
84905841919
-
Trends in incidence and management of cancer of the ampulla of Vater
-
Rostain F, Hamza S, Drouillard A, Faivre J, Bouvier AM and Lepage C: Trends in incidence and management of cancer of the ampulla of Vater. World J Gastroenterol 20:10144-10150, 2014.
-
(2014)
World J Gastroenterol
, vol.20
, pp. 10144-10150
-
-
Rostain, F.1
Hamza, S.2
Drouillard, A.3
Faivre, J.4
Bouvier, A.M.5
Lepage, C.6
-
32
-
-
33845607709
-
Predictors for patterns of failure after pancreaticoduodenectomy in ampullary cancer
-
Hsu HP, Yang TM, Hsieh YH, Shan YS and Lin PW: Predictors for patterns of failure after pancreaticoduodenectomy in ampullary cancer. Ann Surg Oncol 14:50-60, 2007.
-
(2007)
Ann Surg Oncol
, vol.14
, pp. 50-60
-
-
Hsu, H.P.1
Yang, T.M.2
Hsieh, Y.H.3
Shan, Y.S.4
Lin, P.W.5
-
33
-
-
0031418208
-
Development of esophageal metaplasia and adenocarcinoma in a rat surgical model without the use of a carcinogen
-
Goldstein SR, Yang GY, Curtis SK, Reuhl KR, Liu BC, Mirvish SS, Newmark HL and Yang CS: Development of esophageal metaplasia and adenocarcinoma in a rat surgical model without the use of a carcinogen. Carcinogenesis 18:2265-2270, 1997.
-
(1997)
Carcinogenesis
, vol.18
, pp. 2265-2270
-
-
Goldstein, S.R.1
Yang, G.Y.2
Curtis, S.K.3
Reuhl, K.R.4
Liu, B.C.5
Mirvish, S.S.6
Newmark, H.L.7
Yang, C.S.8
-
34
-
-
79959525960
-
The bile acid membrane receptor TGR5: A valuable metabolic target
-
Pols TW, Noriega LG, Nomura M, Auwerx J and Schoonjans K: The bile acid membrane receptor TGR5: A valuable metabolic target. Dig Dis 29:37-44, 2011.
-
(2011)
Dig Dis
, vol.29
, pp. 37-44
-
-
Pols, T.W.1
Noriega, L.G.2
Nomura, M.3
Auwerx, J.4
Schoonjans, K.5
-
35
-
-
84880907693
-
The bile acid membrane receptor TGR5: A novel pharmacological target in metabolic, inflammatory and neoplastic disorders
-
Stepanov V, Stankov K and Mikov M: The bile acid membrane receptor TGR5: A novel pharmacological target in metabolic, inflammatory and neoplastic disorders. J Recept Signal Transduct Res 33:213-223, 2013.
-
(2013)
J Recept Signal Transduct Res
, vol.33
, pp. 213-223
-
-
Stepanov, V.1
Stankov, K.2
Mikov, M.3
-
36
-
-
84946594940
-
The G-protein-coupled bile acid receptor Gpbar1 (TGR5) suppresses gastric cancer cell proliferation and migration through antagonizing STAT3 signaling pathway
-
Guo C, Su J, Li Z, Xiao R, Wen J, Li Y, Zhang M, Zhang X, Yu D, Huang W, et al: The G-protein-coupled bile acid receptor Gpbar1 (TGR5) suppresses gastric cancer cell proliferation and migration through antagonizing STAT3 signaling pathway. Oncotarget 6:34402-34413, 2015.
-
(2015)
Oncotarget
, vol.6
, pp. 34402-34413
-
-
Guo, C.1
Su, J.2
Li, Z.3
Xiao, R.4
Wen, J.5
Li, Y.6
Zhang, M.7
Zhang, X.8
Yu, D.9
Huang, W.10
-
37
-
-
33846345695
-
Involvement of membrane-type bile acid receptor M-BAR/TGR5 in bile acid-induced activation of epidermal growth factor receptor and mitogen-activated protein kinases in gastric carcinoma cells
-
Yasuda H, Hirata S, Inoue K, Mashima H, Ohnishi H and Yoshiba M: Involvement of membrane-type bile acid receptor M-BAR/TGR5 in bile acid-induced activation of epidermal growth factor receptor and mitogen-activated protein kinases in gastric carcinoma cells. Biochem Biophys Res Commun 354:154-159, 2007.
-
(2007)
Biochem Biophys Res Commun
, vol.354
, pp. 154-159
-
-
Yasuda, H.1
Hirata, S.2
Inoue, K.3
Mashima, H.4
Ohnishi, H.5
Yoshiba, M.6
-
38
-
-
84881464516
-
The bile acid receptor TGR5 does not interact with β-arrestins or traffic to endosomes but transmits sustained signals from plasma membrane rafts
-
Jensen DD, Godfrey CB, Niklas C, Canals M, Kocan M, Poole DP, Murphy JE, Alemi F, Cottrell GS, Korbmacher C, et al: The bile acid receptor TGR5 does not interact with β-arrestins or traffic to endosomes but transmits sustained signals from plasma membrane rafts. J Biol Chem 288:22942-22960, 2013.
-
(2013)
J Biol Chem
, vol.288
, pp. 22942-22960
-
-
Jensen, D.D.1
Godfrey, C.B.2
Niklas, C.3
Canals, M.4
Kocan, M.5
Poole, D.P.6
Murphy, J.E.7
Alemi, F.8
Cottrell, G.S.9
Korbmacher, C.10
|