Hepatitis B Virus Genotypes and Spontaneous Hepatitis B e Antigen Seroconversion in Taiwanese Hepatitis B Carriers

Journal of Medical Virology

Volumn 72, Issue 3, 2004, Pages 363-369

  Kao, Jia Horng ^a,b   Chen, Pei Jer ^a   Lai, Ming Yang ^a   Chen, Ding Shinn ^a  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Chronic hepatitis; Hepatitis B e antigen; Hepatitis B genotype; Hepatitis B virus; Seroconversion

Indexed keywords

ALANINE AMINOTRANSFERASE; ANTIVIRUS AGENT; HEPATITIS B(E) ANTIGEN;

ADULT; AGE; AGED; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; ASIAN; CONFIDENCE INTERVAL; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE COURSE; FEMALE; FOLLOW UP; GENOTYPE; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; NONHUMAN; SEROCONVERSION; TAIWAN; VIRUS CARRIER;

HEPATITIS B VIRUS;

EID: 84984578737     PISSN: 01466615     EISSN: None     Source Type: Journal    
DOI: 10.1002/jmv.10534     Document Type: Article

References (33)

1. Brook MG, Karayiannis P, Thomas HC. 1989. Which patients with chronic hepatitis B virus infection will respond to α-interferon therapy? A statistical analysis of predictive factors. Hepatology 10:761-763.
2. Chang MH, Sung JL, Lee CY, Chen CJ, Chen JS, Hsu HY, Lee PI, Chen DS. 1989. Factors affecting clearance of hepatitis B e antigen in hepatitis B surface antigen carrier children. J Pediatr 115:385-390.
3. Chisari FV, Ferrari C. 1995. Hepatitis B immunopathogenesis, Annu Rev Immunol 13:29-60.
4. Chu CJ, Lok AS. 2002. Clinical significance of hepatitis B virus genotypes. Hepatology 35:1274-1276.
5. Chu CJ, Hussain M, Lok AS. 2002. Hepatitis B virus genotype B is associated with earlier HBeAg seroconversion compared with hepatitis B virus genotype C. Gastroenterology 122:1756-1762.
6. Farci P, Purcell RH. 2000. Clinical significance of hepatitis C virus genotypes and quasispecies. Semin Liver Dis 20:103-126.
7. Kao JH. 2002a. Clinical relevance of hepatitis B viral genotypes: A case of de1'ja' vu? J Gastroenterol Hepatol 17:113-115.
8. Kao JH. 2002b. Hepatitis B viral genotypes: Clinical relevance and molecular characteristics. J Gastroenterol Hepatol 17:643-650.
9. Kao JH, Chen DS. 2000. Overview of hepatitis B and C viruses, In: Goedert JJ, editor. Infectious causes of cancer: Targets for intervention. Totowa, NJ: Humana Press, Inc. pp 313-330.
10. Kao JH, Chen DS. 2001. Hepatitis B virus genotypes and hepatocellular carcinoma in Japan-reply. Gastroenterology 120:1564-1565.
11. Kao JH, Chen DS. 2002. Global control of hepatitis B virus infection. Lancet Infect Dis 2:395-403.
12. Kao JH, Wood M, Chen PJ, Lai MY, Chen DS. 1999. Comparison of two methods for quantification of hepatitis B viral DNA. J Gastroenterol Hepatol 14:423-426.
13. Kao JH, Wu NH, Chen PJ, Lai MY, Chen DS. 2000a. Hepatitis B genotypes and the response to interferon therapy. J Hepatol 33: 998-1002.
14. Kao JH, Chen PJ, Lai MY, Chen DS. 2000b. Hepatitis B genotypes correlate with clinical outcomes in patients with chronic hepatitis B. Gastroenterology 118:554-559.
15. Kao JH, Chen PJ, Lai MY, Chen DS. 2001. Acute exacerbations of chronic hepatitis B are rarely associated with superinfection of hepatitis B virus. Hepatology 34:817-823,
16. Kao JH, Chen PJ, Lai MY, Chen DS. 2002a. Clinical and virological aspects of blood donors infected with hepatitis B virus genotypes B and C. J Clin Microbiol 40:22-25.
17. Kao JH, Chen PJ, Lai MY, Chen DS. 2002b. Genotypes and clinical phenotypes of hepatitis B virus in patients with chronic hepatitis B virus infection. J Clin Microbiol 40:1207-1209.
18. Kao JH, Chen PJ, Lai MY, Chen DS. 2003. Basal core promoter mutations of hepatitis B virus increase the risk of hepatocellular carcinoma in hepatitis B carriers. Gastroenterology 124:327-334.
19. Kwok S, Higuchi R. 1989. Avoiding false positives with PCR. Nature 339:237-238.
20. Liaw YF. 1997. Current therapeutic trends in therapy for chronic viral hepatitis. J Gastroenterol Hepatol 12:S346-S353.
21. Liaw YF, Chu CM, Su IJ, Huang MJ, Lin DY, Chang-Chien CS. 1983. Clinical and histological events preceding hepatitis B e antigen seroconversion in chronic type B hepatitis. Gastroenterology 84: 216-219.
22. Liaw YF, Tai DI, Chu CM, Chen TJ. 1988. The development of cirrhosis in patients with chronic type B hepatitis: A prospective study. Hepatology 8:493-496.
23. Lindh M, Hannoun C, Dhillon AP, Norkrans G, Horal P. 1999. Core promoter mutations and genotypes in relation to viral replication and liver damage in East Asian hepatitis B virus carriers. J Infect Dis 179:775-782.
24. Lok AS, Lai CL. 1990. Acute exacerbations in Chinese patients with chronic hepatitis B virus (HBV) infection. Incidence, predisposing factors, and etiology. J Hepatol 10:29-34.
25. Lok AS, Lai CL, Wu PC, Leung EK, Lam TS. 1987. Spontaneous hepatitis B e antigen to antibody seroconversion and reversion in Chinese patients with chronic hepatitis B virus infection. Gastroenterology 92:1839-1843.
26. Maddrey WC. 2000. Hepatitis B: An important public health issue. J Med Virol 61:362-366.
27. Magnius LO, Norder H. 1995. Subtypes, genotypes, and molecular epidemiology of the hepatitis B virus as reflected by sequence variability of the S-gene. Intervirology 38:24-34.
28. Orito E, Mizokami M, Sakugawa H, Michitaka K, Ishikawa K, Ichida T, Okanoue T, Yotsuyanagi H, Iino S. 2001a. A case-control study for clinical and molecular biological differences between hepatitis B viruses of genotypes B and C. Japan HBV Genotype Research Group. Hepatology 33:218-223.
29. Orito E, Ichida T, Sakugawa H, Sata M, Horiike N, Hino K, Okita K, Okanoue T, Iino S, Tanaka E, Suzuki K, Watanabe H, Hige S, Mizokami M. 2001b. Geographic distribution of hepatitis B virus (HBV) genotype in patients with chronic HBV infection in Japan. Hepatology 34:590-594.
30. Perrillo RP, Schiff ER, Davis GL, Bodenheimer HC, Lindsay K, Payne J, Dienstag JL. 1990. A randomized, controlled trial of interferon alfa-2b alone and after prednisone withdrawal for the treatment of chronic hepatitis B. N Engl J Med 323:295-301.
31. Realdi G, Fattovich G, Hadziyannis S, Schalm SW, Almasio P, Sanchez-Tapias J, Christensen E, Giustina G, Noventa F. 1994. Survival and prognostic factors in 366 patients with compensated cirrhosis type B: A multicenter study. The Investigators of the European Concerted Action on Viral Hepatitis (EUROHEP). J Hepatol 21:656-666.
32. Stuyver L, De Gendt S, Van Geyt C, Zoulim F, Fried M, Schinazi RF, Rossau R. 2000. A new genotype of hepatitis B virus: Complete genome and phylogenetic relatedness. J Gen Virol 81:67-74.
33. Yang HI, Lu SN, Liaw YF, You SL, Sun CA, Wang LY, Hsiao C, Chen PJ, Chen DS, Chen CJ. 2002. Hepatitis B e antigen and the risk of hepatocellular carcinoma. N Engl J Med 347:168-174.