Gene expression profiling of the effects of organic dust in lung epithelial and THP-1 cells reveals inductive effects on inflammatory and immune response genes

Physiological Genomics

Volumn 48, Issue 4, 2016, Pages 281-289

  Boggaram, Vijay ^a   Loose, David S ^b   Gottipati, Koteswara R ^a   Natarajan, Kartiga ^a   Mitchell, Courtney T ^a  

^a UNIVERSITY OF TEXAS HEALTH CENTER   (United States)

^b UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

Cytokines; Dust exposure; Inflammation; Lung epithelium; Occupational lung diseases

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 3; CXCL1 CHEMOKINE; CXCL2 CHEMOKINE; CYSTEINE RICH PROTEIN 61; CYTOCHROME P450 4B1; EARLY GROWTH RESPONSE FACTOR 1; EPITHELIAL DERIVED NEUTROPHIL ACTIVATING FACTOR 78; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 11; INTERLEUKIN 1BETA; INTERLEUKIN 32; INTERLEUKIN 6; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; MANGANESE SUPEROXIDE DISMUTASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; PROSTAGLANDIN ENDOPEROXIDASE SYNTHASE 2; PROSTAGLANDIN SYNTHASE; RANTES; RNA 18S; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR ETS 1; TRANSCRIPTION FACTOR FOSB; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; AUTACOID; CHEMOKINE; CYTOKINE; DUST;

A549 CELL LINE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRONCHUS MUCOSA; CELL DEATH; CELL FUNCTION; CELL MATURATION; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DNA MICROARRAY; DOWN REGULATION; DUST EXPOSURE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE INDUCTION; HUMAN; HUMAN CELL; IMMUNE RESPONSE GENE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INFLAMMATORY CELL; LEUKEMIA CELL LINE; LUNG ALVEOLUS EPITHELIUM CELL; MONOCYTE LIKE CELL; MOUSE; MTS ASSAY; NONHUMAN; NORMAL HUMAN; ORGANIC DUST; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; CYTOLOGY; DRUG EFFECTS; DUST; EPITHELIUM CELL; GENETICS; IMMUNOLOGY; LUNG; METABOLISM; PNEUMONIA; POULTRY; PROCEDURES;

ANIMALS; CHEMOKINES; CYTOKINES; DUST; EPITHELIAL CELLS; FEMALE; GENE EXPRESSION PROFILING; HUMANS; INFLAMMATION MEDIATORS; LUNG; MICE, INBRED C57BL; PNEUMONIA; POULTRY;

EID: 84983804547     PISSN: 10948341     EISSN: 15312267     Source Type: Journal    
DOI: 10.1152/physiolgenomics.00096.2015     Document Type: Article

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