메뉴 건너뛰기




Volumn 31, Issue 7, 2016, Pages 1088-1099

Induction of cardiac FGF23/FGFR4 expression is associated with left ventricular hypertrophy in patients with chronic kidney disease

Author keywords

Chronic kidney disease; Fibroblast growth factor 23; Fibroblast growth factor receptor 4; Klotho; Left ventricular hypertrophy

Indexed keywords

CALCINEURIN; FIBROBLAST GROWTH FACTOR 23; FIBROBLAST GROWTH FACTOR RECEPTOR 4; KLOTHO PROTEIN; PHOSPHATE; TRANSCRIPTION FACTOR NFAT; BIOLOGICAL MARKER; FGFR4 PROTEIN, HUMAN; FIBROBLAST GROWTH FACTOR;

EID: 84983740565     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfv421     Document Type: Article
Times cited : (167)

References (55)
  • 1
    • 49249104701 scopus 로고    scopus 로고
    • Fibroblast growth factor 23 and mortality among patients undergoing hemodialysis
    • Gutierrez OM, Mannstadt M, Isakova T et al. Fibroblast growth factor 23 and mortality among patients undergoing hemodialysis. N Engl J Med 2008;359:584-592
    • (2008) N Engl J Med , vol.359 , pp. 584-592
    • Gutierrez, O.M.1    Mannstadt, M.2    Isakova, T.3
  • 2
    • 84880313916 scopus 로고    scopus 로고
    • Evolving importance of kidney disease: From subspecialty to global health burden
    • Eckardt KU, Coresh J, Devuyst O et al. Evolving importance of kidney disease: from subspecialty to global health burden. Lancet 2013;382:158-169
    • (2013) Lancet , vol.382 , pp. 158-169
    • Eckardt, K.U.1    Coresh, J.2    Devuyst, O.3
  • 3
    • 84859831465 scopus 로고    scopus 로고
    • Cardiovascular disease in children with chronic kidney disease
    • Mitsnefes MM. Cardiovascular disease in children with chronic kidney disease. J Am Soc Nephrol 2012;23:578-585
    • (2012) J Am Soc Nephrol , vol.23 , pp. 578-585
    • Mitsnefes, M.M.1
  • 4
    • 4644221457 scopus 로고    scopus 로고
    • Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization
    • Go AS, Chertow GM, Fan D et al. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med 2004;351:1296-1305
    • (2004) N Engl J Med , vol.351 , pp. 1296-1305
    • Go, A.S.1    Chertow, G.M.2    Fan, D.3
  • 5
    • 0036695863 scopus 로고    scopus 로고
    • Cardiovascular mortality in children and young adults with end-stage kidney disease
    • Parekh RS, Carroll CE, Wolfe RA et al. Cardiovascular mortality in children and young adults with end-stage kidney disease. J Pediatr 2002;141:191-197
    • (2002) J Pediatr , vol.141 , pp. 191-197
    • Parekh, R.S.1    Carroll, C.E.2    Wolfe, R.A.3
  • 6
    • 66349097180 scopus 로고    scopus 로고
    • Fibroblast growth factor 23 and left ventricular hypertrophy in chronic kidney disease
    • Gutiérrez OM, Januzzi JL, Isakova T et al. Fibroblast growth factor 23 and left ventricular hypertrophy in chronic kidney disease. Circulation 2009;119:2545-2552
    • (2009) Circulation , vol.119 , pp. 2545-2552
    • Gutiérrez, O.M.1    Januzzi, J.L.2    Isakova, T.3
  • 7
    • 84939847116 scopus 로고    scopus 로고
    • Klotho protects against indoxyl sulphate-induced myocardial hypertrophy
    • Yang K, Wang C, Nie L et al. Klotho protects against indoxyl sulphate-induced myocardial hypertrophy. J Am Soc Nephrol 2015;26:2434-2446
    • (2015) J Am Soc Nephrol , vol.26 , pp. 2434-2446
    • Yang, K.1    Wang, C.2    Nie, L.3
  • 8
    • 80555148939 scopus 로고    scopus 로고
    • FGF23 induces left ventricular hypertrophy
    • Faul C, Amaral AP, Oskouei B et al. FGF23 induces left ventricular hypertrophy. J Clin Invest 2011;121:4393-4408
    • (2011) J Clin Invest , vol.121 , pp. 4393-4408
    • Faul, C.1    Amaral, A.P.2    Oskouei, B.3
  • 9
    • 75149133934 scopus 로고    scopus 로고
    • Masked hypertension associates with left ventricular hypertrophy in children with CKD
    • Mitsnefes MM, Flynn J, Cohn S et al. Masked hypertension associates with left ventricular hypertrophy in children with CKD. J Am Soc Nephrol 2010;21:137-144
    • (2010) J Am Soc Nephrol , vol.21 , pp. 137-144
    • Mitsnefes, M.M.1    Flynn, J.2    Cohn, S.3
  • 10
    • 84871188650 scopus 로고    scopus 로고
    • Multidirectional myocardial systolic function in hemodialysis patients with preserved left ventricular ejection fraction and different left ventricular geometry
    • Wang H, Liu J, Xao XD et al. Multidirectional myocardial systolic function in hemodialysis patients with preserved left ventricular ejection fraction and different left ventricular geometry. Nephrol Dial Transplant 2012;27:4422-4429
    • (2012) Nephrol Dial Transplant , vol.27 , pp. 4422-4429
    • Wang, H.1    Liu, J.2    Xao, X.D.3
  • 11
    • 80051556651 scopus 로고    scopus 로고
    • Cardiac geometry in children receiving chronic peritoneal dialysis: Findings from the International Pediatric Peritoneal Dialysis Network (IPPN) registry
    • Bakkaloglu SA, Borzych D, Soo Ha I et al. Cardiac geometry in children receiving chronic peritoneal dialysis: findings from the International Pediatric Peritoneal Dialysis Network (IPPN) registry. Clin J Am Soc Nephrol 2011;6:1926-1933
    • (2011) Clin J Am Soc Nephrol , vol.6 , pp. 1926-1933
    • Bakkaloglu, S.A.1    Borzych, D.2    Soo Ha, I.3
  • 12
    • 18444375871 scopus 로고    scopus 로고
    • Mutant FGF-23 responsible for autosomal dominant hypophosphatemic rickets is resistant to proteolytic cleavage and causes hypophosphatemia in vivo
    • Shimada T, Muto T, Urakawa I et al. Mutant FGF-23 responsible for autosomal dominant hypophosphatemic rickets is resistant to proteolytic cleavage and causes hypophosphatemia in vivo. Endocrinology 2002;143:3179-3182
    • (2002) Endocrinology , vol.143 , pp. 3179-3182
    • Shimada, T.1    Muto, T.2    Urakawa, I.3
  • 13
    • 27744545673 scopus 로고    scopus 로고
    • Fibroblast growth factor-23 mitigates hyperphosphatemia but accentuates calcitriol deficiency in chronic kidney disease
    • Gutierrez OM, Isakova T, Rhee E et al. Fibroblast growth factor-23 mitigates hyperphosphatemia but accentuates calcitriol deficiency in chronic kidney disease. J Am Soc Nephrol 2005;16:2205-2215
    • (2005) J Am Soc Nephrol , vol.16 , pp. 2205-2215
    • Gutierrez, O.M.1    Isakova, T.2    Rhee, E.3
  • 14
    • 84893560373 scopus 로고    scopus 로고
    • Disordered FGF23 and mineral metabolism in children with CKD
    • Portale AA, Wolf M, Juppner H et al. Disordered FGF23 and mineral metabolism in children with CKD. Clin J Am Soc Nephrol 2014;9:344-353
    • (2014) Clin J Am Soc Nephrol , vol.9 , pp. 344-353
    • Portale, A.A.1    Wolf, M.2    Juppner, H.3
  • 15
  • 16
    • 79957870135 scopus 로고    scopus 로고
    • Fibroblast growth factor 23 is elevated before parathyroid hormone and phosphate in chronic kidney disease
    • Isakova T, Wahl P, Vargas GS et al. Fibroblast growth factor 23 is elevated before parathyroid hormone and phosphate in chronic kidney disease. Kidney Int 2011;79:1370-1378
    • (2011) Kidney Int , vol.79 , pp. 1370-1378
    • Isakova, T.1    Wahl, P.2    Vargas, G.S.3
  • 17
    • 84866366740 scopus 로고    scopus 로고
    • Update on fibroblast growth factor 23 in chronic kidney disease
    • Wolf M. Update on fibroblast growth factor 23 in chronic kidney disease. Kidney Int 2012;7:737-747
    • (2012) Kidney Int , vol.7 , pp. 737-747
    • Wolf, M.1
  • 18
    • 84866396001 scopus 로고    scopus 로고
    • Residual renal function is an independent determinant of serum FGF-23 levels in dialysis patients
    • Viaene L, Bammens B, Meijers BK et al. Residual renal function is an independent determinant of serum FGF-23 levels in dialysis patients. Nephrol Dial Transplant 2012;27:2017-2022
    • (2012) Nephrol Dial Transplant , vol.27 , pp. 2017-2022
    • Viaene, L.1    Bammens, B.2    Meijers, B.K.3
  • 19
    • 80655135433 scopus 로고    scopus 로고
    • Fibroblast growth factor 23 in patients undergoing peritoneal dialysis
    • Isakova T, Xie H, Barchi-Chung A et al. Fibroblast growth factor 23 in patients undergoing peritoneal dialysis. Clin J Am Soc Nephrol 2011;6:2688-2695
    • (2011) Clin J Am Soc Nephrol , vol.6 , pp. 2688-2695
    • Isakova, T.1    Xie, H.2    Barchi-Chung, A.3
  • 20
    • 76149101238 scopus 로고    scopus 로고
    • Circulating fibroblast growth factor 23 in patients with end-stage renal disease treated by peritoneal dialysis is intact and biologically active
    • Shimada T, Urakawa I, Isakova T et al. Circulating fibroblast growth factor 23 in patients with end-stage renal disease treated by peritoneal dialysis is intact and biologically active. J Clin Endocrinol Metab 2010;95:578-585
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 578-585
    • Shimada, T.1    Urakawa, I.2    Isakova, T.3
  • 21
    • 79958724181 scopus 로고    scopus 로고
    • Fibroblast growth factor 23 and risks of mortality and end-stage renal disease in patients with chronic kidney disease
    • Isakova T, Xie H, Yang W et al. Fibroblast growth factor 23 and risks of mortality and end-stage renal disease in patients with chronic kidney disease. JAMA 2011;305:2432-2439
    • (2011) JAMA , vol.305 , pp. 2432-2439
    • Isakova, T.1    Xie, H.2    Yang, W.3
  • 23
    • 79955603792 scopus 로고    scopus 로고
    • Elevated fibroblast growth factor 23 is a risk factor for kidney transplant loss and mortality
    • Wolf M, Molnar MZ, Amaral AP et al. Elevated fibroblast growth factor 23 is a risk factor for kidney transplant loss and mortality. J Am Soc Nephrol 2011;22:956-966
    • (2011) J Am Soc Nephrol , vol.22 , pp. 956-966
    • Wolf, M.1    Molnar, M.Z.2    Amaral, A.P.3
  • 24
    • 33646578195 scopus 로고    scopus 로고
    • Regulation of fibroblast growth factor-23 signaling by Klotho
    • Kurosu H, Ogawa Y, Miyoshi M et al. Regulation of fibroblast growth factor-23 signaling by Klotho. J Biol Chem 2006;281:6120-6123
    • (2006) J Biol Chem , vol.281 , pp. 6120-6123
    • Kurosu, H.1    Ogawa, Y.2    Miyoshi, M.3
  • 25
    • 33845631059 scopus 로고    scopus 로고
    • Klotho converts canonical FGF receptor into a specific receptor for FGF23
    • Urakawa I, Yamazaki Y, Shimada T et al. Klotho converts canonical FGF receptor into a specific receptor for FGF23. Nature 2006;444:770-774
    • (2006) Nature , vol.444 , pp. 770-774
    • Urakawa, I.1    Yamazaki, Y.2    Shimada, T.3
  • 27
    • 84930436563 scopus 로고    scopus 로고
    • Klotho and phosphate are modulators of pathologic uremic cardiac remodeling
    • Hu MC, Shi M, Cho HJ et al. Klotho and phosphate are modulators of pathologic uremic cardiac remodeling. J Am Soc Nephrol 2015;26:1290-1302
    • (2015) J Am Soc Nephrol , vol.26 , pp. 1290-1302
    • Hu, M.C.1    Shi, M.2    Cho, H.J.3
  • 28
    • 84929353472 scopus 로고    scopus 로고
    • Soluble Klotho protects against uremic cardiomyopathy independent of fibroblast growth factor 23 and phosphate
    • Xie J, Yoon J, An SW et al. Soluble Klotho protects against uremic cardiomyopathy independent of fibroblast growth factor 23 and phosphate. J Am Soc Nephrol 2015;26:1150-1160
    • (2015) J Am Soc Nephrol , vol.26 , pp. 1150-1160
    • Xie, J.1    Yoon, J.2    An, S.W.3
  • 29
    • 84878487994 scopus 로고    scopus 로고
    • FGF23 is a novel regulator of intracellular calcium and cardiac contractility in addition to cardiac hypertrophy
    • Touchberry CD, Green TM, Tchikrizov V et al. FGF23 is a novel regulator of intracellular calcium and cardiac contractility in addition to cardiac hypertrophy. Am J Physiol Endocrinol Metab 2013;304:E863-E873
    • (2013) Am J Physiol Endocrinol Metab , vol.304 , pp. E863-E873
    • Touchberry, C.D.1    Green, T.M.2    Tchikrizov, V.3
  • 30
    • 84862122363 scopus 로고    scopus 로고
    • Fibroblast growth factor 23 and the heart
    • Faul C. Fibroblast growth factor 23 and the heart. Curr Opin Nephrol Hypertens 2012;21:369-375
    • (2012) Curr Opin Nephrol Hypertens , vol.21 , pp. 369-375
    • Faul, C.1
  • 31
    • 84945942478 scopus 로고    scopus 로고
    • Activation of cardiac fibroblast growth factor receptor 4 causes left ventricular hypertrophy
    • Grabner A, Amaral AP, Schramm K et al. Activation of cardiac fibroblast growth factor receptor 4 causes left ventricular hypertrophy. Cell Metab 2015;22:1020-1032
    • (2015) Cell Metab , vol.22 , pp. 1020-1032
    • Grabner, A.1    Amaral, A.P.2    Schramm, K.3
  • 32
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in realtime RT-PCR
    • Pfaffl MW. A new mathematical model for relative quantification in realtime RT-PCR. Nucleic Acids Res 2001;29:e45
    • (2001) Nucleic Acids Res , vol.29 , pp. e45
    • Pfaffl, M.W.1
  • 33
    • 0032540267 scopus 로고    scopus 로고
    • A calcineurin-dependent transcriptional pathway for cardiac hypertrophy
    • Molkentin JD, Lu JR, Antos CL et al. A calcineurin-dependent transcriptional pathway for cardiac hypertrophy. Cell 1998;93:215-228
    • (1998) Cell , vol.93 , pp. 215-228
    • Molkentin, J.D.1    Lu, J.R.2    Antos, C.L.3
  • 34
    • 57849107130 scopus 로고    scopus 로고
    • Signaling to gene expression: Calcium, calcineurin and NFAT
    • Rao A. Signaling to gene expression: calcium, calcineurin and NFAT. Nat Immunol 2009;10:3-5
    • (2009) Nat Immunol , vol.10 , pp. 3-5
    • Rao, A.1
  • 35
    • 0032450903 scopus 로고    scopus 로고
    • Cardiomyocytes and non-muscle cells in cardiac hypertrophy: A molecular perspective
    • Gupta M, Gupta MP, Arcilla RA et al. Cardiomyocytes and non-muscle cells in cardiac hypertrophy: a molecular perspective. Prog Pediatr Cardiol 1998;9:183-197
    • (1998) Prog Pediatr Cardiol , vol.9 , pp. 183-197
    • Gupta, M.1    Gupta, M.P.2    Arcilla, R.A.3
  • 36
    • 80052532269 scopus 로고    scopus 로고
    • Clinical significance of FGF-23 measurement in dialysis patients
    • Jongbloed F, Galassi A, Cozzolino M et al. Clinical significance of FGF-23 measurement in dialysis patients. Clin Nephrol 2011;76:201-209
    • (2011) Clin Nephrol , vol.76 , pp. 201-209
    • Jongbloed, F.1    Galassi, A.2    Cozzolino, M.3
  • 37
    • 33646367420 scopus 로고    scopus 로고
    • Fibroblast growth factor 23 is a counterregulatory phosphaturic hormone for vitamin D
    • Liu S, Tang W, Zhou J et al. Fibroblast growth factor 23 is a counterregulatory phosphaturic hormone for vitamin D. J Am Soc Nephrol 2006;17:1305-1315
    • (2006) J Am Soc Nephrol , vol.17 , pp. 1305-1315
    • Liu, S.1    Tang, W.2    Zhou, J.3
  • 38
    • 34948866160 scopus 로고    scopus 로고
    • Parathyroid hormone regulates fibroblast growth factor-23 in a mouse model of primary hyperparathyroidism
    • Kawata T, Imanishi Y, Kobayashi K et al. Parathyroid hormone regulates fibroblast growth factor-23 in a mouse model of primary hyperparathyroidism. J Am Soc Nephrol 2007;18:2683-2688
    • (2007) J Am Soc Nephrol , vol.18 , pp. 2683-2688
    • Kawata, T.1    Imanishi, Y.2    Kobayashi, K.3
  • 39
    • 85047687476 scopus 로고    scopus 로고
    • Roles of phosphate and fibroblast growth factor 23 in cardiovascular disease
    • Scialla JJ, Wolf M. Roles of phosphate and fibroblast growth factor 23 in cardiovascular disease. Nat Rev Nephrol 2014;10:268-278
    • (2014) Nat Rev Nephrol , vol.10 , pp. 268-278
    • Scialla, J.J.1    Wolf, M.2
  • 40
    • 84868119464 scopus 로고    scopus 로고
    • Fibroblast growth factor 23 and left ventricular hypertrophy in children on dialysis
    • Seeherunvong W, Abitbol CL, Chandar J et al. Fibroblast growth factor 23 and left ventricular hypertrophy in children on dialysis. Pediatr Nephrol 2012;27:2129-2136
    • (2012) Pediatr Nephrol , vol.27 , pp. 2129-2136
    • Seeherunvong, W.1    Abitbol, C.L.2    Chandar, J.3
  • 41
    • 84890954922 scopus 로고    scopus 로고
    • Association of novel biomarkers of cardiovascular stress with left ventricular hypertrophy and dysfunction: Implications for screening
    • Xanthakis V, Larson MG, Wollert KC et al. Association of novel biomarkers of cardiovascular stress with left ventricular hypertrophy and dysfunction: implications for screening. J Am Heart Assoc 2013;2:e000399
    • (2013) J Am Heart Assoc , vol.2 , pp. e000399
    • Xanthakis, V.1    Larson, M.G.2    Wollert, K.C.3
  • 42
    • 84870488179 scopus 로고    scopus 로고
    • Circulating alphaKlotho influences phosphate handling by controlling FGF23 production
    • Smith RC, O'Bryan LM, Farrow EG et al. Circulating alphaKlotho influences phosphate handling by controlling FGF23 production. J Clin Invest 2012;122:4710-4715
    • (2012) J Clin Invest , vol.122 , pp. 4710-4715
    • Smith, R.C.1    O'Bryan, L.M.2    Farrow, E.G.3
  • 43
    • 84915782238 scopus 로고    scopus 로고
    • The kidney is the principal organ mediating klotho effects
    • Lindberg K, Amin R, Moe OW et al. The kidney is the principal organ mediating klotho effects. J Am Soc Nephrol 2014;25:2169-2175
    • (2014) J Am Soc Nephrol , vol.25 , pp. 2169-2175
    • Lindberg, K.1    Amin, R.2    Moe, O.W.3
  • 44
    • 84873283825 scopus 로고    scopus 로고
    • The impact of nephrectomy and renal transplantation on serum levels of soluble Klotho protein
    • Akimoto T, Kimura T, Watanabe Y et al. The impact of nephrectomy and renal transplantation on serum levels of soluble Klotho protein. Transplant Proc 2013;45:134-146
    • (2013) Transplant Proc , vol.45 , pp. 134-146
    • Akimoto, T.1    Kimura, T.2    Watanabe, Y.3
  • 45
    • 84870509189 scopus 로고    scopus 로고
    • AlphaKlotho: FGF23 coreceptor and FGF23-regulating hormone
    • Juppner H, Wolf M. alphaKlotho: FGF23 coreceptor and FGF23-regulating hormone. J Clin Invest 2012;122:4336-4339
    • (2012) J Clin Invest , vol.122 , pp. 4336-4339
    • Juppner, H.1    Wolf, M.2
  • 46
    • 0346849707 scopus 로고    scopus 로고
    • Klotho, a gene related to a syndromeresembling human premature aging, functions in a negative regulatory circuit of vitamin D endocrine system
    • Tsujikawa H, Kurotaki Y, Fujimori T et al. Klotho, a gene related to a syndromeresembling human premature aging, functions in a negative regulatory circuit of vitamin D endocrine system. Mol Endocrinol 2003;17:2393-2403
    • (2003) Mol Endocrinol , vol.17 , pp. 2393-2403
    • Tsujikawa, H.1    Kurotaki, Y.2    Fujimori, T.3
  • 47
    • 33744937606 scopus 로고    scopus 로고
    • Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family
    • Zhang X, Ibrahimi OA, Olsen SK et al. Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family. J Biol Chem 2006;281:15694-15700
    • (2006) J Biol Chem , vol.281 , pp. 15694-15700
    • Zhang, X.1    Ibrahimi, O.A.2    Olsen, S.K.3
  • 48
    • 84880278299 scopus 로고    scopus 로고
    • Parsing good versus bad signaling pathways in the heart: Role of calcineurin-nuclear factor of activated T-cells
    • Molkentin JD. Parsing good versus bad signaling pathways in the heart: role of calcineurin-nuclear factor of activated T-cells. Circ Res 2013;113:16-19
    • (2013) Circ Res , vol.113 , pp. 16-19
    • Molkentin, J.D.1
  • 49
    • 84871518109 scopus 로고    scopus 로고
    • Molecular basis of physiological heart growth: Fundamental concepts and new players
    • Maillet M, van Berlo JH, Molkentin JD. Molecular basis of physiological heart growth: fundamental concepts and new players. Nat Rev Mol Cell Biol 2013;14:38-48
    • (2013) Nat Rev Mol Cell Biol , vol.14 , pp. 38-48
    • Maillet, M.1    Van Berlo, J.H.2    Molkentin, J.D.3
  • 50
    • 77949890048 scopus 로고    scopus 로고
    • Heart-specific deletion of CnB1 reveals multiple mechanisms whereby calcineurin regulates cardiac growth and function
    • Maillet M, Davis J, Auger-Messier M et al. Heart-specific deletion of CnB1 reveals multiple mechanisms whereby calcineurin regulates cardiac growth and function. J Biol Chem 2010;285:6716-6724
    • (2010) J Biol Chem , vol.285 , pp. 6716-6724
    • Maillet, M.1    Davis, J.2    Auger-Messier, M.3
  • 51
    • 80051538639 scopus 로고    scopus 로고
    • Cardioprotective effect of calcineurin inhibition in an animal model of renal disease
    • Di Marco GS, Reuter S, Kentrup D et al. Cardioprotective effect of calcineurin inhibition in an animal model of renal disease. Eur Heart J 2011;32:1935-1945
    • (2011) Eur Heart J , vol.32 , pp. 1935-1945
    • Di Marco, G.S.1    Reuter, S.2    Kentrup, D.3
  • 52
    • 84885951113 scopus 로고    scopus 로고
    • FGF23 and mineral metabolism in the early post-renal transplantation period
    • Wesseling-Perry K, Pereira RC, Tsai E et al. FGF23 and mineral metabolism in the early post-renal transplantation period. Pediatr Nephrol 2013;28:2207-2215
    • (2013) Pediatr Nephrol , vol.28 , pp. 2207-2215
    • Wesseling-Perry, K.1    Pereira, R.C.2    Tsai, E.3
  • 53
    • 84869462410 scopus 로고    scopus 로고
    • Serum level of fibroblast growth factor 23 in maintenance renal transplant patients
    • Sanchez Fructuoso AI, Maestro ML, Perez-Flores I et al. Serum level of fibroblast growth factor 23 in maintenance renal transplant patients. Nephrol Dial Transplant 2012;27:4227-4235
    • (2012) Nephrol Dial Transplant , vol.27 , pp. 4227-4235
    • Sanchez Fructuoso, A.I.1    Maestro, M.L.2    Perez-Flores, I.3
  • 54
    • 84986563782 scopus 로고    scopus 로고
    • Treatment of established left ventricular hypertrophy with fibroblast growth factor receptor blockade in an animal model of CKD
    • Di Marco GS, Reuter S, Kentrup D et al. Treatment of established left ventricular hypertrophy with fibroblast growth factor receptor blockade in an animal model of CKD. Nephrol Dial Transplant 2014;29:2028-2035
    • (2014) Nephrol Dial Transplant , vol.29 , pp. 2028-2035
    • Di Marco, G.S.1    Reuter, S.2    Kentrup, D.3
  • 55
    • 84863550146 scopus 로고    scopus 로고
    • FGF23 neutralization improves chronic kidney disease-associated hyperparathyroidism yet increases mortality
    • Shalhoub V, Shatzen EM, Ward SC et al. FGF23 neutralization improves chronic kidney disease-associated hyperparathyroidism yet increases mortality. J Clin Invest 2012;122:2543-2553
    • (2012) J Clin Invest , vol.122 , pp. 2543-2553
    • Shalhoub, V.1    Shatzen, E.M.2    Ward, S.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.