Association of polymorphisms in SPARC and NLRP2 genes with rheumatoid arthritis in a Chinese Han population

Modern Rheumatology

Volumn 25, Issue 1, 2016, Pages 67-71

  Yang, Xing Lin ^a   Hu, Zhong Dan ^a   Wu, Qian ^a   Liu, Xi ^b   Liu, Qi Ji ^c   Zhang, Yuan Chao ^a   Yang, Qing Rui ^a  

^a SHANDONG PROVINCIAL HOSPITAL AFFILIATED TO SHANDONG UNIVERSITY   (China)

^b HANDAN CENTRAL HOSPITAL   (China)

^c SHANDONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

NLRP2; Rheumatoid arthritis; Singlenucleotide polymorphism; SPARC

Indexed keywords

OSTEONECTIN; PEPTIDES AND PROTEINS; PROTEIN NLRP2; UNCLASSIFIED DRUG; NLRP2 PROTEIN, HUMAN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SPARC PROTEIN, HUMAN;

ADULT; ALLELE; ARTICLE; CHINESE; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC RISK; GENOTYPE; HAPLOTYPE; HUMAN; INHERITANCE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SINGLE NUCLEOTIDE POLYMORPHISM; ASIAN CONTINENTAL ANCESTRY GROUP; CASE CONTROL STUDY; GENETIC PREDISPOSITION; GENETICS; MIDDLE AGED;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADULT; ALLELES; ARTHRITIS, RHEUMATOID; ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HAPLOTYPES; HUMANS; MALE; MIDDLE AGED; OSTEONECTIN; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 84983500203     PISSN: 14397595     EISSN: 14397609     Source Type: Journal    
DOI: 10.3109/14397595.2014.903595     Document Type: Article

References (24)

1. Fueki H, H ino R, Y oshioka M, N akamura M, T okura Y. C alcinosis cutis associated with primary Sjogren ’ s syndrome: strong expression of osteonectin and matrix Gla protein. Rheumatology (Oxford). 2011; 50(12): 2318-20.
2. Sharma SM, Choi D, Planck SR, Harrington CA, Austin CR, Lewis JA, et al. Insights in to the pathogenesis of axial spondyloarthropathy based on gene expression profi les. Arthritis Res Ther. 2009; 11(6): 168.
3. Nakamura S, Kamihagi K, Satakeda H, Katayama M, Pan H, Okamoto H, et al. Enhancement of SPARC (osteonectin) synthesis in arthritic cartilage. Increased levels in synovial fl uids from patients with rheumatoid arthritis and regulation by growth factors and cytokines in chondrocyte cultures. Arthritis Rheum. 1996; 39(4): 539-51.
4. Pontillo A, Girardelli M, Kamada A J, Pancotto J A, Donadi E A, Crovella S, Sandrin-Garcia P. Polimorphisms in infl ammasome genes are involved in the predisposition to systemic lupus erythematosus. Autoimmunity. 2012; 45(4): 271-78.
5. Kinoshita T, Wang Y, Hasegawa M, Imamura R, Suda T. PYPAF3, a PYRIN-containing APAF-1-like protein, is a feedback regulator of caspase-1-dependent interleukin-1beta secretion. J Biol Chem. 2005; 280(23): 21720-25.
6. Fontalba A, Gutierrez O, Fernandez-Luna JL. NLRP2, an inhibitor of the NF-kappaB pathway, is transcriptionally activated by NFkappaB and exhibits a nonfunctional allelic variant. J Immunol. 2007; 179(12): 8519-24.
7. Bruey JM, Bruey-Sedano N, Newman R, Chandler S, Stehlik C, Reed JC. PAN1/NALP2/PYPAF2, an inducible infl ammatory mediatorthat regulates NF-kappaB and caspase-1 activation in macrophages. J Biol Chem. 2004; 279(50): 51897-907.
8. Saklatvala J, Sarsfi eld SJ, Townsend Y. Pig interleukin 1. Purifi cation of two immunologically diff erent leukocyte proteins that cause cartilage resorption, lymphocyte activation, and fever. J Exp Med. 1985; 162(4): 1208-22.
9. Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, et al. The American Rheumatism Association 1987 revised criteria for the classifi cation of rheumatoid arthritis. Arthritis Rheum. 1988; 31(3): 315-24.
10. Shi YY, He L. SHEsis, a powerful software platform for analyses of linkage disequilibrium, haplotype construction, and genetic association at polymorphism loci. Cell Res. 2005; 15(2): 97-98.
11. Termine JD, Kleinman HK, Whitson SW, Conn KM, McGarvey ML, Martin GR. Osteonectin, a bone-specifi c protein linking mineral to collagen. Cell. 1981; 26(1 Pt 1): 99-105.
12. Lorenzo J, Horowitz M, Choi Y. Osteoimmunology: interactions of the bone and immune system. Endocr Rev. 2008; 29(4): 403-40.
13. Rempel S A, Hawley R C, Gutierrez J A, Mouzon E, Bobbitt K R, Lemke N, et al. Splenic and immune alterations of the Sparcnull mouse accompany a lack of immune response. Genes Immun. 2007; 8(3): 262-74.
14. Tremble PM, Lane TF, Sage EH, Werb Z. SPARC, a secreted protein associated with morphogenesis and tissue remodeling, induces expression of metalloproteinases in fi broblasts through a novel extracellular matrix-dependent pathway. J Cell Biol. 1993; 121(6): 1433-44.
15. Lane TF, Iruela-Arispe ML, Johnson RS, Sage EH. SPARC is a source of copper-binding peptides that stimulate angiogenesis. J Cell Biol. 1994; 125(4): 929-43.
16. Mundlos S, Schwahn B, Reichert T, Zabel B. Distribution of osteonectin mRNA and protein during human embryonic and fetal development. J Histochem Cytochem. 1992; 40(2): 283-91.
17. Malaval L, Fournier B, Delmas P D. Radioimmunoassay for osteonectin. Concentrations in bone, nonmineralized tissues, and blood. J Bone Miner Res. 1987; 2(5): 457-65.
18. Jundt G, Berghauser K H, Termine J D, Schulz A. O steonectin– a diff erentiation marker of bone cells. Cell Tissue Res. 1987; 248(2): 409-15.
19. Pacifici M, Oshima O, Fisher L W, Young M F, Shapiro I M, Leboy PS. Changes in osteonectin distribution and levels are associated with mineralization of the chicken tibial growth cartilage. Calcif Tissue Int. 1990; 47(1): 51-61.
20. Okada Y, Takeuchi N, Tomita K, Nakanishi I, Nagase H. Immunolocalization of matrix metalloproteinase 3 (stromelysin) in rheumatoid synovioblasts (B cells): correlation with rheumatoid arthritis. Ann Rheum Dis. 1989; 48(8): 645-53.
21. Vuorio T, Kahari VM, Black C, Vuorio E. Expression of osteonectin, decorin, and transforming growth factor-beta 1 genes in fi broblasts cultured from patients with systemic sclerosis and morphea. J Rheumatol. 1991; 18(2): 247-51.
22. Pawlowski K, Pio F, Chu Z, Reed J C, Godzik A. PAAD-a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001; 26(2): 85-7.
23. Iwamoto M, Koike T, Nakashima K, Sato K, Kato Y. I nterleukin 1: a regulator of chondrocyte proliferation. Immunol Lett. 1989; 21(2): 153-56.
24. Goldring M B, Birkhead J, Sandell L J, Kimura T, Krane S M. Interleukin 1 suppresses expression of cartilage-specifi c types II and IX collagens and increases types I and III collagens in human chondrocytes. J Clin Invest. 1988; 82(6): 2026-37.