Dental caries – not just holes in teeth! A perspective

Molecular Oral Microbiology

Volumn 31, Issue 3, 2016, Pages 228-233

  Bowen, W H ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

biofilms; dental caries; diffusion; glucosyltransferase; matrix; saliva

Indexed keywords

BIOLOGICAL MARKER; GLUCOSYLTRANSFERASE;

BIOFILM; CLINICAL RESEARCH; DENTAL CARIES; IN VIVO STUDY; MOUTH; REVIEW; TOOTH;

EID: 84983397968     PISSN: 20411006     EISSN: 20411014     Source Type: Journal    
DOI: 10.1111/omi.12132     Document Type: Review

References (17)

1. Appleton, J.L.T. (1944) Dental Caries. Bacterial Infection, with Special Reference to Dental Practice. London: Henry Kempton, pp. 332.
2. Bowen, W.H. (2013a) The Stephan Curve revisited. Odontology 101: 2–8.
3. Bowen, W.H. (2013b) Rodent model in caries research. Odontology 101: 9–14.
4. Bowen, W.H. and Koo, H. (2011) Biology of Streptococcus mutans-derived glucosyltransferases: role in extracellular matrix formation of cariogenic biofilms. Caries Res 45: 69–86.
5. Bowen, W.H., Amsbaugh, S.M., Monell-Torrens, S. et al. (1980) A method to assess cariogenic potential of foodstuffs. J Am Dent Assoc 100: 677–681.
6. Falsetta, M.L., Klein, M.I., Colonne, P.M. et al. (2014) Symbiotic relationship between Streptococcus mutans and Candida albicans synergizes virulence of plaque biofilms in vivo. Infect Immun 82: 1968–1981.
7. Flemming, H.C. and Wingender, J. (2010) The biofilm matrix. Nat Rev Microbiol 9: 623–633.
8. Horev, B., Klein, M.I., Hwang, G. et al. (2015) pH-activated nanoparticles for controlled topical delivery of farnesol to disrupt oral biofilm virulence. ACS Nano 9: 2390–2404.
9. Köhler, B. and Andréen, I. (2012) Mutans streptococci and caries prevalence in children after early maternal caries prevention: a follow-up at 19 years of age. Caries Res 46: 474–480.
10. Koo, H., Xiao, J., Klein, M.I. and Jeon, J.G. (2010) Exopolysaccharides produced by Streptococcus mutans glucosyltransferases modulate the establishment of microcolonies within multispecies biofilms. J Bacteriol 192: 3024–3032.
11. Liao, S., Klein, M.I., Heim, K.P. et al. (2014) Streptococcus mutans extracellular DNA is upregulated during growth in biofilms, actively released via membrane vesicles, and influenced by components of the protein secretion machinery. J Bacteriol 196: 2355–2366.
12. Meyerowitz, C. and Watson, G.E. (1998) The efficacy of an intraoral fluoride-releasing system in irradiated head and neck cancer patients: a preliminary study. J Am Dent Assoc 129: 1252–1259.
13. Robinson, C. (2011) Mass transfer of therapeutics through natural human plaque biofilms: a model for therapeutic delivery to pathological bacterial biofilms. Arch Oral Biol 56: 829–836.
14. Svensäter, G., Borgström, M., Bowden, G.H. and Edwardsson, S. (2003) The acid-tolerant microbiota associated with plaque from initial caries and healthy tooth surfaces. Caries Res 37: 395–403.
15. Tanzer, J.M., Livingston, J. and Thompson, A.M. (2001) The microbiology of primary dental caries in humans. J Dent Educ 65: 1028–1037.
16. Vacca-Smith, A.M. and Bowen, W.H. (1998) Binding properties of streptococcal glucosyltransferases for hydroxyapatite, saliva-coated hydroxyapatite, and bacterial surfaces. Arch Oral Biol 43: 103–110.
17. Vacca-Smith, A.M., Venkitaraman, A.R., Quivey, R.G. Jr and Bowen, W.H. (1996) Interactions of streptococcal glucosyltransferases with alpha-amylase and starch on the surface of saliva-coated hydroxyapatite. Arch Oral Biol 41: 291–298.