Ex vivo detection of tumoral lymph nodes of colorectal origin with fluorescence imaging after intraoperative intravenous injection of indocyanine green

Journal of Surgical Oncology

Volumn 114, Issue 3, 2016, Pages 348-353

  Liberale, Gabriel ^a   Galdon, Maria Gomez ^a   Moreau, Michel ^a   Vankerckhove, Sophie ^a   El Nakadi, Issam ^a   Larsimont, Denis ^a   Donckier, Vincent ^a   Bourgeois, Pierre ^a  

^a JULES BORDET INSTITUTE   (Belgium)

Author keywords

colorectal neoplasms; ex vivo; fluorescence imaging; indocyanine green; lymph nodes; metastatic

Indexed keywords

INDOCYANINE GREEN;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; COLON RESECTION; COLORECTAL CANCER; COLORECTAL SURGERY; CYTOREDUCTIVE SURGERY; EX VIVO STUDY; FEMALE; FLUORESCENCE IMAGING; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; INTRAOPERATIVE PERIOD; LYMPH NODE DISSECTION; LYMPH NODE METASTASIS; MALE; MICROMETASTASIS; NEAR INFRARED IMAGING SYSTEM; PERITONEUM METASTASIS; PRIORITY JOURNAL; RECTUM ANTERIOR RESECTION; SENSITIVITY AND SPECIFICITY; TUMOR INVASION;

EID: 84983348006     PISSN: 00224790     EISSN: 10969098     Source Type: Journal    
DOI: 10.1002/jso.24318     Document Type: Article

References (15)

1. Choi J, Oh SN, Yeo DM, et al.: Computed tomography and magnetic resonance imaging evaluation of lymph node metastasis in early colorectal cancer. World J Gastroenterol 2015; 21:556–562.
2. Lu YY, Chen JH, Ding HJ, et al.: A systematic review and meta-analysis of pretherapeutic lymph node staging of colorectal cancer by 18F-FDG PET or PET/CT. Nucl Med Commun 2012; 33:1127–1133.
3. Ishizawa T, Fukushima N, Shibahara J, et al.: Real-time identification of liver cancers by using indocyanine green fluorescent imaging. Cancer 2009; 115:2491–2504.
4. Van der Vorst JR, Schaafsma BE, Hutteman M, et al.: Near-infrared fluorescence-Guided resection of colorectal liver metastases. Cancer 2013; 119:3411–3418.
5. Liberale G, Vankerckhove S, Caldon MG, et al.: Fluorescence imaging after indocyanine green injection for detection of peritoneal metastases in patients undergoing cytoreductive surgery for peritoneal carcinomatosis from colorectal cancer: A pilot study. Ann Surg 2016 [epub ahead of print].
6. Liberale G, Vankerckhove S, Galdon MG, et al.: Fluorescence imaging after intraoperative intravenous injection of indocyanine green for detection of lymph node metastases in colorectal cancer. Eur J Surg Oncol 2015; 41:1256–1260.
7. Schaafsma BE, Mieog JSD, Hutteman M, et al.: The clinical use of indocyanine green as a near-infrared fluorescent contrast agent for image-guided oncologic surgery. J Surg Oncol 2011; 104:323–332.
8. Gulec SA, Hoenie E, Hostetter R, et al.: PET probe-guided surgery: Applications and clinical protocol. World J Surg Oncol 2007; 5:65.
9. Yokoyama J, Fujimaki M, Ohba S, et al.: A feasibility study of NIR fluorescent image-guided surgery in head and neck cancer based on the assessment of optimum surgical time as revealed through dynamic imaging. Onco Targets Ther 2013; 6:325–330.
10. Digonnet A, van Kerckhove S, Moreau M, et al.: Near infrared fluorescent imaging after intravenous injection of indocyanine green during neck dissection in patients with head and neck cancer: A feasibility study. Head Neck 2016; 38:E1833–E1837.
11. Maeda H, Wu J, Sawa T, et al.: Tumor vascular permeability and the EPR effect in macromolecular therapeutics. J Control Release 2000; 65:271–284.
12. Maeda H: The link between infection and cancer: Tumor vasculature, free radicals, and drug delivery to tumors via the EPR effect. Cancer Sci 2013; 104:779–789.
13. Hirche C, Mohr Z, Kneif S, et al.: Ultrastaging of colorectal cancer by sentinel node biopsy using fluorescence navigation with indocyanine green. Int J Colorectal Dis 2012; 27:319–324.
14. van der Pas MH, Ankersmit M, Stockmann HB, et al.: Laparoscopic sentinel lymph node identification in patients with colon carcinoma using a near-infrared dye: Description of a new technique and feasibility study. J Laparoendosc Adv Surg Tech A 2013; 23:367–371.
15. Liberale G, Vankerckhove S, Gomez Galdon M, et al. Sentinel Lymph node detection by indocyanine green fluorescence imaging in primary colorectal cancer. W J Surg (submitted).